27 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Discovery and preclinical validation of a translationally optimized mitochondrial complex I modulator for Alzheimer’s disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC13538682/
  3. Jul 2026
  4. www.sciencedirect.com www.sciencedirect.com
    NAT10 inhibition corrects nuclear defects in tau mutant human neurons and extends lifespan in a Drosophila tauopathy model
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S258900422602239X
  5. Apr 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Recapitulation of plaque formation, tau pathology, and neurodegeneration in a human 3D matrix model of Alzheimer’s disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC13106978/
  7. www.biorxiv.org www.biorxiv.org
    Discovery and Preclinical Validation of a Clinically Optimized Mitochondrial Complex I Modulator for Alzheimer’s Disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.64898/2026.04.10.717554v1
  8. www.biorxiv.org www.biorxiv.org
    Autophagy activators normalize aberrant Tau proteostasis and rescue synapses in human familial Alzheimer’s disease iPSC-derived cortical organoids
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2025.06.25.661453v2
  9. Mar 2026
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Alzheimer’s disease pathology degrades an NMDA receptor-dependent spontaneous activity pattern in cortico-hippocampal circuits
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC13045655/
  11. Dec 2025
  12. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Oxidized MIF is an Alzheimer’s disease drug target relaying external risk factors to tau pathology
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com:5037/science/article/pii/S2666379125005932
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PP2A methylesterase, PME‐1, and PP2A methyltransferase, LCMT‐1, control sensitivity to impairments caused by injury‐related oligomeric tau
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12701366/
  14. Sep 2025
  15. www.sciencedirect.com www.sciencedirect.com
    Biomarker-related phospho-tau217 appears in synapses around Aβ plaques prior to tau tangle in cerebral cortex of preclinical Alzheimer’s disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S221112472500974X
  16. May 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dysregulated calcium signaling in the aged macaque entorhinal cortex associated with tau hyperphosphorylation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12069431/
  18. Jan 2025
  19. dx.doi.org dx.doi.org
    Intramural hematomas and astrocytic infiltration precede perivascular inflammation in a rat model of repetitive low-level blast injury
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    dx.doi.org/10.1093/jnen/nlaf003
  20. Apr 2024
  21. www.sciencedirect.com www.sciencedirect.com
    Human iPSC 4R tauopathy model uncovers modifiers of tau propagation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867424003064
  22. Oct 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Cerebral organoids derived from patients with Alzheimer’s disease with PSEN1/2 mutations have defective tissue patterning and altered development
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124723013220
  24. Aug 2023
  25. www.sciencedirect.com www.sciencedirect.com
    IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124723009002
  26. Jun 2023
  27. www.biorxiv.org www.biorxiv.org
    KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2023.06.12.543777v1
  28. Aug 2022
  29. alz-journals.onlinelibrary.wiley.com alz-journals.onlinelibrary.wiley.com
    Phosphorylated tau sites that are elevated in Alzheimer's disease fluid biomarkers are visualized in early neurofibrillary tangle maturity levels in the post mortem brain
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.12749
  30. May 2022
  31. link.springer.com link.springer.com
    Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1186/s13024-022-00526-y
  32. Mar 2022
  33. www.sciencedirect.com www.sciencedirect.com
    Familial natural short sleep mutations reduce Alzheimer pathology in mice
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004222002346
  34. Sep 2021
  35. www.sciencedirect.com www.sciencedirect.com
    Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S089662732100578X
  36. Aug 2021
  37. www.sciencedirect.com www.sciencedirect.com
    Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276521006225
  38. Jul 2021
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Conserved Cytoskeletal Signaling Cascade Mediates Neurotoxicity of FTDP-17 Tau Mutations In Vivo
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC5761430/
  40. Oct 2020
  41. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Tau phosphorylation by glycogen synthase kinase 3β modulates AChE expression
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/10.1111/jnc.15189
  42. link.springer.com link.springer.com
    Plasma Leptin Reflects Progression of Neurofibrillary Pathology in Animal Model of Tauopathy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1007/s10571-020-00972-6
  43. Sep 2020
  44. www.jneurosci.org www.jneurosci.org
    AMPK Preferentially Depresses Retrograde Transport of Axonal Mitochondria during Localized Nutrient Deprivation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    jneurosci.org/content/40/25/4798
  45. Jan 2020
  46. onlinelibrary.wiley.com onlinelibrary.wiley.com
    High specificity of widely used phospho‐tau antibodies validated using a quantitative whole‐cell based assay
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/10.1111/jnc.14830
  47. Nov 2018
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Conserved Cytoskeletal Signaling Cascade Mediates Neurotoxicity of FTDP-17 Tau Mutations In Vivo
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC5761430/
  49. Nov 2017
  50. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Physiologically relevant factors influence tau phosphorylation by leucine‐rich repeat kinase 2
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/10.1002/jnr.23614/full