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Basal body docking failure triggers centriole clustering and elimination in mammalian spermatogenesis

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1. scibot 22 Jul 2026
  
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  AB_2238184
  
  DOI: 10.1038/s44319-026-00872-8
  
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link.springer.com/article/10.1038/s44319-026-00872-8
Jun 2026
aacrjournals.org aacrjournals.org

Targeting SUV4-20H Epigenetic Enzymes Enhances Topoisomerase II Poisoning in Prostate Cancer

1
1. scibot 30 Jun 2026
  
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  RRID:AB_2238184
  
  DOI: 10.1158/0008-5472.CAN-24-3974
  
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aacrjournals.org/cancerres/article/86/1/236/771157/Targeting-SUV4-20H-Epigenetic-Enzymes-Enhances
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Overexpression of the ERG oncogene in prostate cancer identifies candidates for PARP inhibitor-based radiosensitization

1
1. scibot 18 Mar 2026
  
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  RRID:AB_2238184
  
  DOI: 10.1172/JCI194949
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12987654/
Mar 2025
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Targeting Replication Fork Processing Synergizes with PARP Inhibition to Potentiate Lethality in Homologous Recombination Proficient Ovarian Cancers

1
1. scibot 20 Mar 2025
  
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  RRID:AB_2238184
  
  DOI: 10.1002/advs.202410718
  
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advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202410718
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SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair

1
1. scibot 07 Mar 2025
  
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  RRID:AB_2238184
  
  DOI: 10.1016/j.molcel.2025.02.004
  
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sciencedirect.com/science/article/pii/S1097276525001091
Sep 2024
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Transient splicing inhibition causes persistent DNA damage and chemotherapy vulnerability in triple-negative breast cancer

1
1. scibot 17 Sep 2024
  
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  AB_2238184
  
  DOI: 10.1016/j.celrep.2024.114751
  
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sciencedirect.com/science/article/pii/S2211124724011021
Feb 2024
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β1 integrin mediates unresponsiveness to PI3Kα inhibition for radiochemosensitization of 3D HNSCC models

1
1. scibot 02 Feb 2024
  
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  RRID:AB_2238184
  
  DOI: 10.1016/j.biopha.2024.116217
  
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sciencedirect.com/science/article/pii/S0753332224000982
Jan 2024
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BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair

1
1. scibot 20 Jan 2024
  
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  RRID:AB_2238184
  
  DOI: 10.1016/j.molcel.2023.12.025
  
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sciencedirect.com/science/article/pii/S1097276523010717
Feb 2023
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PARylation of BRCA1 limits DNA break resection through BRCA2 and EXO1

1
1. scibot 03 Feb 2023
  
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  RRID:AB_2238184
  
  DOI: 10.1016/j.celrep.2023.112060
  
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sciencedirect.com/science/article/pii/S2211124723000712
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Temporal phosphoproteomics reveals WEE1-dependent control of 53BP1 pathway

1
1. scibot 11 Jan 2023
  
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  RRID:AB_2238184
  
  DOI: 10.1016/j.isci.2022.105806
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9827073/
Dec 2022
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The EMT transcription factor ZEB1 governs a fitness-promoting but vulnerable DNA replication stress response

1
1. scibot 18 Dec 2022
  
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  RRID:AB_2238184
  
  DOI: 10.1016/j.celrep.2022.111819
  
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sciencedirect.com/science/article/pii/S2211124722017119
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors

1
1. scibot 16 Dec 2022
  
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  RRID:AB_2238184
  
  DOI: 10.1126/sciadv.abq0648
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9733930/
www.science.org www.science.org

NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors

1
1. scibot 13 Dec 2022
  
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  RRID:AB_2238184
  
  DOI: 10.1126/sciadv.abq0648
  
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science.org/doi/10.1126/sciadv.abq0648
Apr 2022
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H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ

1
1. scibot 21 Apr 2022
  
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  RRID:AB_2238184
  
  DOI: 10.1016/j.molcel.2022.03.030
  
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sciencedirect.com/science/article/pii/S1097276522002684
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Heterochromatic repeat clustering imposes a physical barrier on homologous recombination to prevent chromosomal translocations

1
1. scibot 21 Apr 2022
  
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  RRID:AB_2238184
  
  DOI: 10.1016/j.molcel.2022.03.033
  
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sciencedirect.com/science/article/pii/S1097276522002891
Feb 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis

1
1. scibot 12 Feb 2022
  
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  RRID:AB_2238184
  
  DOI: 10.7554/eLife.68677
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8824475/
Nov 2021
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A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization

1
1. scibot 18 Nov 2021
  
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  RRID:AB_2238184
  
  DOI: 10.1016/j.molcel.2021.10.017
  
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sciencedirect.com/science/article/pii/S1097276521009096
Aug 2021
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UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

1
1. scibot 07 Aug 2021
  
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  RRID:AB_2238184
  
  DOI: 10.1016/j.cell.2018.11.024
  
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sciencedirect.com/science/article/pii/S0092867418315162
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 05 Aug 2021
  
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  AB_2238184
  
  DOI: 10.1016/j.devcel.2018.10.004
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6286383/
Jun 2021
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The nuclear kinesin KIF18B promotes 53BP1-mediated DNA double-strand break repair

1
1. scibot 30 Jun 2021
  
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  RRID:AB_2238184
  
  DOI: 10.1016/j.celrep.2021.109306
  
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sciencedirect.com/science/article/pii/S2211124721006823
Jan 2021
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A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans

1
1. scibot 05 Jan 2021
  
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  RRID:AB_2238184
  
  DOI: 10.1016/j.celrep.2020.108559
  
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  RRID:AB_2238184 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720315485
Jan 2020
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Acquired Resistance of EGFR-Mutated Lung Cancer to Tyrosine Kinase Inhibitor Treatment Promotes PARP Inhibitor Sensitivity

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2238184
  
  DOI: 10.1016/j.celrep.2019.05.058
  
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sciencedirect.com/science/article/pii/S2211124719306874
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The Initiation of Meiotic Sex Chromosome Inactivation Sequesters DNA Damage Signaling from Autosomes in Mouse Spermatogenesis

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2238184
  
  DOI: 10.1016/j.cub.2019.11.064
  
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sciencedirect.com/science/article/pii/S0960982219315660
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PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2238184
  
  DOI: 10.1016/j.molcel.2019.10.008
  
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sciencedirect.com/science/article/pii/S1097276519307683
Nov 2018
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Untitled document

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sciencedirect.com/science/article/pii/S1534580718308256
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The BRCT Domains of the BRCA1 and BARD1 Tumor Suppressors Differentially Regulate Homology-Directed Repair and Stalled Fork Protection

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2238184
  
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  RRID:AB_2238184 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276518306762
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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ncbi.nlm.nih.gov/pmc/articles/PMC6039718/
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Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1097276518303927
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Targeting p38α Increases DNA Damage, Chromosome Instability, and the Anti-tumoral Response to Taxanes in Breast Cancer Cells

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1535610818301818
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BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1535610818300199
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe

2
1. scibot 05 Nov 2018
  
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  RRID:AB_2238184
  
  Curator: @evieth
  
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  RRID:AB_2238184 RRIDCUR:Validated
2. scibot 05 Nov 2018
  
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  RRID:AB_2238184
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5786504/