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Tumors hijack macrophages for iron supply to promote bone metastasis and anemia

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1. scibot 04 Sep 2025
  
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  DOI: 10.1016/j.cell.2025.08.013
  
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sciencedirect.com/science/article/pii/S0092867425009274
Aug 2025
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Long-range deployment of tumor-antigen-specific cytotoxic T lymphocytes inhibits lung metastasis of breast cancer

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1. scibot 28 Aug 2025
  
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  DOI: 10.1016/j.devcel.2025.08.003
  
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sciencedirect.com/science/article/pii/S1534580725005039
Jul 2025
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Differential substrate degradation by super-degron: EGFP in wild-type mouse cells, PD-1 requires CRBN humanization

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.112992
  
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sciencedirect.com/science/article/pii/S2589004225012532
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tumor integrin-targeted glucose oxidase enzyme promotes ROS-mediated cell death that combines with interferon alpha therapy for tumor control

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1. scibot 04 Jul 2025
  
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  DOI: 10.1158/1535-7163.MCT-24-0163
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11695183/
Jun 2025
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Cisplatin and temozolomide combinatorial treatment triggers hypermutability and immune surveillance in experimental cancer models

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1. scibot 13 Jun 2025
  
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  DOI: 10.1016/j.ccell.2025.05.014
  
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sciencedirect.com/science/article/pii/S1535610825002235
May 2025
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Protocol for assessing mobilization of peritoneal B cells to the pre-metastatic omentum in an orthotopic mouse model of ovarian cancer

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1. scibot 19 May 2025
  
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  DOI: 10.1016/j.xpro.2025.103806
  
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sciencedirect.com/science/article/pii/S2666166725002126
Apr 2025
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PPARγ-dependent remodeling of translational machinery in adipose progenitors is impaired in obesity

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1. scibot 18 Apr 2025
  
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  DOI: 10.1016/j.celrep.2024.114945
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12002411/
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Rorγt-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens

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1. scibot 05 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.03.020
  
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sciencedirect.com/science/article/pii/S0092867425002934
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BPS Publications

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1. scibot 01 Apr 2025
  
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  DOI: 10.1111/bph.70025
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70025
Mar 2025
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Metallophilic marginal zone macrophages cross-prime CD8+ T cell-mediated protective immunity against blood-borne tumors

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.02.027
  
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sciencedirect.com/science/article/pii/S1074761325000949
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Immunotherapy with low-dose IL-2 attenuates vascular injury in mice with diabetic and neovascular retinopathy by restoring the balance between Foxp3+ Tregs and CD8+ T cells

1
1. scibot 29 Mar 2025
  
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  DOI: 10.1007/s00125-025-06412-8
  
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link.springer.com/article/10.1007/s00125-025-06412-8
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Splenic TNF-α signaling potentiates the innate-to-adaptive transition of antiviral NK cells

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1. scibot 04 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.02.012
  
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sciencedirect.com/science/article/pii/S1074761325000792
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Inflammatory cytokines mediate the induction of and awakening from metastatic dormancy

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1. scibot 04 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115388
  
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sciencedirect.com/science/article/pii/S2211124725001597
Feb 2025
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A microRNA-regulated transcriptional state defines intratumoral CD8+ T cells that respond to immunotherapy

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1. scibot 14 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115301
  
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sciencedirect.com/science/article/pii/S2211124725000725
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Rev-erb-α antagonism in alveolar macrophages protects against pneumococcal infection in elderly mice

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1. scibot 06 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115273
  
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sciencedirect.com/science/article/pii/S2211124725000440
Dec 2024
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Vimentin modulates regulatory T cell receptor-ligand interactions at distal pole complex, leading to dysregulated host response to viral pneumonia

1
1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115056
  
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sciencedirect.com/science/article/pii/S2211124724014074
Sep 2024
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H3K9 lactylation in malignant cells facilitates CD8+ T cell dysfunction and poor immunotherapy response

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1. scibot 04 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114686
  
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sciencedirect.com/science/article/pii/S2211124724010374
Aug 2024
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Nuclear HMGB1 is critical for CD8 T cell IFN-γ production and anti-tumor immunity

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1. scibot 20 Aug 2024
  
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  AB_2242784
  
  DOI: 10.1016/j.celrep.2024.114591
  
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sciencedirect.com/science/article/pii/S2211124724009203
Jul 2024
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Lymphatic-localized Treg-mregDC crosstalk limits antigen trafficking and restrains anti-tumor immunity

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.ccell.2024.06.014
  
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sciencedirect.com/science/article/pii/S1535610824002393
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PARP11 inhibition inactivates tumor-infiltrating regulatory T cells and improves the efficacy of immunotherapies

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1. scibot 17 Jul 2024
  
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  DOI: 10.1016/j.xcrm.2024.101649
  
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sciencedirect.com/science/article/pii/S266637912400363X
Apr 2024
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Claudin-2 upregulation enhances intestinal permeability, immune activation, dysbiosis, and mortality in sepsis

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1. scibot 25 Apr 2024
  
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  DOI: 10.1073/pnas.2217877121
  
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pnas.org/doi/abs/10.1073/pnas.2217877121
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A dopamine D1-like receptor-specific agonist improves the survival of septic mice

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1. scibot 18 Apr 2024
  
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  DOI: 10.1016/j.isci.2024.109587
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11016908/
Mar 2024
www.nature.com www.nature.com

Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease

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1. scibot 08 Mar 2024
  
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  DOI: 10.1038/s41564-024-01617-w
  
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nature.com/articles/s41564-024-01617-w
Feb 2024
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Stem-like progenitor and terminally differentiated TFH-like CD4+ T cell exhaustion in the tumor microenvironment

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1. scibot 16 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113797
  
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sciencedirect.com/science/article/pii/S2211124724001256
Jan 2024
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Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells

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1. scibot 19 Jan 2024
  
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  DOI: 10.1016/j.xcrm.2023.101377
  
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sciencedirect.com/science/article/pii/S2666379123006067
Dec 2023
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IL-18-induced HIF-1α in ILC3s ameliorates the inflammation of C. rodentium-induced colitis

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1. scibot 02 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113508
  
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sciencedirect.com/science/article/pii/S2211124723015206
Oct 2023
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Supplementation with a high-glucose drink stimulates anti-tumor immune responses to glioblastoma via gut microbiota modulation

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113220
  
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sciencedirect.com/science/article/pii/S2211124723012329
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

In vivo modeling of CLL transformation to Richter’s syndrome reveals convergent evolutionary paths and therapeutic vulnerabilities

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1. scibot 07 Sep 2023
  
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  DOI: 10.1158/2643-3230.BCD-22-0082
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9975769/
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Reduced smooth muscle-fibroblasts transformation potentially decreases intestinal wound healing and colitis-associated cancer in ageing mice

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1. scibot 12 Aug 2023
  
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  DOI: 10.1038/s41392-023-01554-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10409725/
Jul 2023
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Liver sinusoidal endothelial cells orchestrate NK cell recruitment and activation in acute inflammatory liver injury

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1. scibot 21 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112836
  
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sciencedirect.com/science/article/pii/S2211124723008471
Jun 2023
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METTL3-mediated m6A methylation orchestrates mRNA stability and dsRNA contents to equilibrate γδ T1 and γδ T17 cells

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1. scibot 27 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112684
  
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sciencedirect.com/science/article/pii/S2211124723006952
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Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration

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1. scibot 21 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112647
  
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sciencedirect.com/science/article/pii/S2211124723006587
Apr 2023
52.53.155.43 52.53.155.43

An immune cell lipid atlas reveals the basis of susceptibility to ferroptosis

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1. scibot 05 Apr 2023
  
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  RRID:AB_2242784
  
  DOI: 10.1101/2023.02.10.528075
  
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52.53.155.43/7b3ec2d05d846404e9e7aaf3ab1e37fa63827484/2023.02.10.528075v1.full-html.html
Mar 2023
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T helper 2 cells control monocyte to tissue-resident macrophage differentiation during nematode infection of the pleural cavity

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1. scibot 28 Mar 2023
  
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  DOI: 10.1016/j.immuni.2023.02.016
  
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sciencedirect.com/science/article/pii/S1074761323000900
Feb 2023
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Repression of the aryl-hydrocarbon receptor prevents oxidative stress and ferroptosis of intestinal intraepithelial lymphocytes

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1. scibot 17 Feb 2023
  
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  DOI: 10.1016/j.immuni.2023.01.023
  
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  DOI: 10.1158/2643-3230.bcd-22-0082
  
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Dec 2022
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Across-cancer immune responses induced by nanovaccines or microvaccines to prevent different cancers and cancer metastasis

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  DOI: 10.1016/j.isci.2022.105511
  
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Nov 2022
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Identification of hematopoietic stem cells residing in the meninges of adult mice at steady state

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Jun 2022
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PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment

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Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity

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Feb 2022
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Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy

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Candida albicans elicits protective allergic responses via platelet mediated T helper 2 and T helper 17 cell polarization

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CXCL10/CXCR3 signaling contributes to an inflammatory microenvironment and its blockade enhances progression of murine pancreatic precancerous lesions

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Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity

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Reticular Fibroblasts Expressing the Transcription Factor WT1 Define a Stromal Niche That Maintains and Replenishes Splenic Red Pulp Macrophages

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Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections

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Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer

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Feb 2021
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Depletion of Toll-Like Receptor-9 Attenuates Renal Tubulointerstitial Fibrosis After Ischemia-Reperfusion Injury

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Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration

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Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis

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Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity

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PD-1 Imposes Qualitative Control of Cellular Transcriptomes in Response to T Cell Activation

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Untitled document

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Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging

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Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms

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