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Scaffolding-dependent CASP1 constrains excessive cell-intrinsic inflammatory signaling in leukemia

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1. scibot 09 Jan 2026
  
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  RRID:AB_2243894
  
  DOI: 10.1016/j.chembiol.2025.12.002
  
  Resource: (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
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sciencedirect.com/science/article/pii/S2451945625003952
Mar 2025
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Visualization of calpain-1 activation during cell death and its role in GSDMD cleavage using chemical probes

1
1. scibot 29 Mar 2025
  
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  RRID:AB_2243894
  
  DOI: 10.1016/j.chembiol.2025.03.002
  
  Resource: (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2451945625000686
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

T3SS translocon induces pyroptosis by direct interaction with NLRC4/NAIP inflammasome

1
1. scibot 16 Feb 2025
  
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  RRID:AB_2243894
  
  DOI: 10.7554/eLife.100820
  
  Resource: (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11828483/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Viral oncogene EBNALP regulates YY1 DNA binding and alters host 3D genome organization

1
1. scibot 13 Feb 2025
  
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  RRID:AB_2243894
  
  DOI: 10.1038/s44319-024-00357-6
  
  Resource: (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11811279/
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 07 Feb 2025
  
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  RRID:AB_2243894
  
  DOI: 10.1111/bph.17344
  
  Resource: (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17344
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

FUBP3 mediates the amyloid-β-induced neuronal NLRP3 expression

1
1. scibot 03 Jan 2025
  
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  RRID:AB_2243894
  
  DOI: 10.4103/NRR.NRR-D-23-01799
  
  Resource: (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11691456/
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Entrectinib inhibits NLRP3 inflammasome and inflammatory diseases by directly targeting NEK7

1
1. scibot 12 Jan 2024
  
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  RRID:AB_2243894
  
  DOI: 10.1016/j.xcrm.2023.101310
  
  Resource: (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10772347/
Dec 2023
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Aedes aegypti saliva modulates inflammasome activation and facilitates flavivirus infection in vitro

1
1. scibot 21 Dec 2023
  
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  RRID:AB_2243894
  
  DOI: 10.1016/j.isci.2023.108620
  
  Resource: (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2589004223026974
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The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases

1
1. scibot 20 Dec 2023
  
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  RRID:AB_2243894
  
  DOI: 10.1016/j.celrep.2023.113581
  
  Resource: (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124723015930
Apr 2023
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The orphan receptor Nur77 binds cytoplasmic LPS to activate the non-canonical NLRP3 inflammasome

1
1. scibot 06 Apr 2023
  
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  RRID:AB_2243894
  
  DOI: 10.1016/j.immuni.2023.03.003
  
  Resource: (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1074761323001231
Jan 2023
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The NLRP1 and CARD8 inflammasomes detect reductive stress

1
1. scibot 19 Jan 2023
  
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  RRID:AB_2243894
  
  DOI: 10.1016/j.celrep.2022.111966
  
  Resource: (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124722018708
Jun 2022
academic.oup.com academic.oup.com

Elevated levels of follicular fatty acids induce ovarian inflammation via ERK1/2 and inflammasome activation in PCOS

1
1. scibot 03 Jun 2022
  
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  RRID:AB_2243894
  
  DOI: 10.1210/clinem/dgac281
  
  Resource: (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
  Curator: @scibot
  
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academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac281/6581607
Jan 2022
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Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1β to downregulate PPARα and FOXO3

1
1. scibot 26 Jan 2022
  
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  RRID:AB_2243894
  
  DOI: 10.1016/j.celrep.2021.110284
  
  Resource: (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S221112472101799X
Jul 2021
rupress.org rupress.org

Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination

1
1. scibot 23 Jul 2021
  
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  2225S
  
  DOI: 10.1083/jcb.202006043
  
  Resource: (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
  Curator: @Naa003
  
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  RRID:AB_2243894 RRIDCUR:Missing
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rupress.org/jcb/article/220/6/e202006043/211984/Parkin-independent-mitophagy-via-Drp1-mediated
May 2021
www.cell.com www.cell.com

Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment

1
1. scibot 21 May 2021
  
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  RRID:AB_2243894
  
  DOI: 10.1016/j.immuni.2021.04.024
  
  Resource: (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
  Curator: @scibot
  
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cell.com/immunity/fulltext/S1074-7613(21)00186-2
Sep 2020
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hGBP1 Coordinates Chlamydia Restriction and Inflammasome Activation through Sequential GTP Hydrolysis

1
1. scibot 13 Sep 2020
  
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  RRID:AB_2243894
  
  DOI: 10.1016/j.celrep.2020.107667
  
  Resource: (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2243894
  
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  RRIDCUR:Validated RRID:AB_2243894
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RRIDCUR:Validated

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sciencedirect.com/science/article/pii/S2211124720306203
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TMEM173 Drives Lethal Coagulation in Sepsis

1
1. scibot 09 Sep 2020
  
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  RRID:AB_2243894
  
  DOI: 10.1016/j.chom.2020.02.004
  
  Resource: (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2243894
  
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  RRIDCUR:Validated RRID:AB_2243894
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RRIDCUR:Validated

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sciencedirect.com/science/article/pii/S1931312820301128
onlinelibrary.wiley.com onlinelibrary.wiley.com

Occludin degradation makes brain microvascular endothelial cells more vulnerable to reperfusion injury in vitro

1
1. scibot 07 Sep 2020
  
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  RRID:AB_2243894
  
  DOI: 10.1111/jnc.15102
  
  Resource: (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2243894
  
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  RRIDCUR:Validated RRID:AB_2243894
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onlinelibrary.wiley.com/doi/10.1111/jnc.15102
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SFTSV Infection Induces BAK/BAX-Dependent Mitochondrial DNA Release to Trigger NLRP3 Inflammasome Activation

1
1. scibot 06 Sep 2020
  
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  RRID:AB_2243894
  
  DOI: 10.1016/j.celrep.2020.02.105
  
  Resource: (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2243894
  
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  RRID:AB_2243894 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720302862
Nov 2017
www.sciencedirect.com www.sciencedirect.com

An Essential Role for SHARPIN in the Regulation of Caspase 1 Activity in Sepsis

1
1. scibot 08 Nov 2017
  
  in Public
  
  caspase 1 p20 antibody (#2225; Cell Signaling Technology
  
  Curator: @bandrow
  
  Curator note: Cell Signaling Technology Cat# 2225, RRID:AB_2243894
  
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  (Cell Signaling Technology Cat# 2225, RRID:AB_2243894)
  
  SciCrunch record: RRID:AB_2243894
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_2243894
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sciencedirect.com/science/article/pii/S0002944016000985