60 Matching Annotations
  1. Aug 2024
  2. www.sciencedirect.com www.sciencedirect.com
    RTEL1 helicase counteracts RAD51-mediated homologous recombination and fork reversal to safeguard replicating genomes
    1
    1. scibot 20 Aug 2024
      AB_2253533

      DOI: 10.1016/j.celrep.2024.114594

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    sciencedirect.com/science/article/pii/S2211124724009239
  3. Feb 2024
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    SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability
    1
    1. scibot 13 Feb 2024
      RRID:AB_2253533

      DOI: 10.1016/j.celrep.2024.113778

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    sciencedirect.com/science/article/pii/S2211124724001062
  5. Oct 2023
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    Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages
    1
    1. scibot 28 Oct 2023
      RRID:AB_2253533

      DOI: 10.1016/j.celrep.2023.113256

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    sciencedirect.com/science/article/pii/S2211124723012688
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    An activity-based functional test for identifying homologous recombination deficiencies across cancer types in real time
    1
    1. scibot 27 Oct 2023
      RRID:AB_2253533

      DOI: 10.1016/j.xcrm.2023.101247

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    sciencedirect.com/science/article/pii/S266637912300424X
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    TERRA R-loops connect and protect sister telomeres in mitosis
    1
    1. scibot 17 Oct 2023
      RRID:AB_2253533

      DOI: 10.1016/j.celrep.2023.113235

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    sciencedirect.com/science/article/pii/S2211124723012470
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    Replication stress and defective checkpoints make fallopian tube epithelial cells putative drivers of high-grade serous ovarian cancer
    1
    1. scibot 01 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113144

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    sciencedirect.com/science/article/pii/S2211124723011567
  10. Jun 2023
  11. www.sciencedirect.com www.sciencedirect.com
    PTBP1 enforces ATR-CHK1 signalling determining the potency of CDC7 inhibitors
    1
    1. scibot 09 Jun 2023
      RRID:AB_2253533

      DOI: 10.1016/j.isci.2023.106951

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    sciencedirect.com/science/article/pii/S2589004223010283
  12. May 2023
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    MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells
    2
    1. scibot 10 May 2023
      RRID: AB_2253533

      DOI: 10.1016/j.celrep.2023.112484

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    2. scibot 10 May 2023
      RRID:AB_2253533

      DOI: 10.1016/j.celrep.2023.112484

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    sciencedirect.com/science/article/pii/S2211124723004953
  14. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    PPP2R1B is modulated by ubiquitination and is essential for spermatogenesis
    1
    1. scibot 05 May 2023
      RAD51

      DOI: 10.1096/fj.202002810R

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    faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202002810R
  15. Apr 2023
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    Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair
    1
    1. scibot 14 Apr 2023
      RRID:AB_2253533

      DOI: 10.1016/j.molcel.2023.03.021

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    sciencedirect.com/science/article/pii/S1097276523002113
  17. Dec 2022
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    Quantification of protein enrichment at site-specific DNA double-strand breaks by chromatin immunoprecipitation in cultured human cells
    1
    1. scibot 17 Dec 2022
      RRID:AB_2253533

      DOI: 10.1016/j.xpro.2022.101917

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    sciencedirect.com/science/article/pii/S2666166722007973
  19. Aug 2022
  20. www.sciencedirect.com www.sciencedirect.com
    CHAMP1 binds to REV7/FANCV and promotes homologous recombination repair
    1
    1. scibot 31 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111297

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    sciencedirect.com/science/article/pii/S2211124722011172
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    Phosphorylation of BRCA1 by ATM upon double-strand breaks impacts ATM function in end-resection: A potential feedback loop
    1
    1. scibot 30 Aug 2022
      AB_2253533

      DOI: 10.1016/j.isci.2022.104944

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    sciencedirect.com/science/article/pii/S2589004222012160
  22. Mar 2022
  23. www.sciencedirect.com www.sciencedirect.com
    BMI-1 regulates DNA end resection and homologous recombination repair
    1
    1. scibot 23 Mar 2022
      RRID:AB_2253533

      DOI: 10.1016/j.celrep.2022.110536

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    sciencedirect.com/science/article/pii/S2211124722002777
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis
    1
    1. scibot 23 Mar 2022
      RRID:AB_2253533

      DOI: 10.1016/j.isci.2022.104008

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    ncbi.nlm.nih.gov/pmc/articles/PMC8931362/
  25. Jan 2022
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair
    1
    1. scibot 05 Jan 2022
      RRID:AB_2253533

      DOI: 10.1016/j.ccell.2019.04.011

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    ncbi.nlm.nih.gov/pmc/articles/PMC8717880/
  27. Dec 2021
  28. www.sciencedirect.com www.sciencedirect.com
    EMSY inhibits homologous recombination repair and the interferon response, promoting lung cancer immune evasion
    1
    1. scibot 28 Dec 2021
      RRID:AB_2253533

      DOI: 10.1016/j.cell.2021.12.005

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    sciencedirect.com/science/article/pii/S0092867421014276
  29. Aug 2021
  30. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 10 Aug 2021
      RRID:AB_2253533

      DOI: 10.1016/j.molcel.2018.11.003

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    sciencedirect.com/science/article/pii/S1097276518309456
  31. europepmc.org europepmc.org
    Untitled document
    1
    1. scibot 05 Aug 2021
      RRID:AB_2253533

      DOI: 10.7554/eLife.38771

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    europepmc.org/articles/PMC6037479/
  32. Jul 2021
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 29 Jul 2021
      RRID:AB_2253533

      DOI: 10.1016/j.molcel.2018.08.020

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    ncbi.nlm.nih.gov/pmc/articles/PMC6202423/
  34. May 2021
  35. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    PPP2R1B is modulated by ubiquitination and is essential for spermatogenesis
    1
    1. scibot 04 May 2021
      RRID:AB_2253533

      DOI: 10.1096/fj.202002810R

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    faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202002810R
  36. Apr 2021
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance
    1
    1. scibot 13 Apr 2021
      RRID:AB_2253533

      DOI: 10.1016/j.molcel.2021.03.032

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    ncbi.nlm.nih.gov/pmc/articles/PMC8153251/
  38. Jan 2021
  39. www.sciencedirect.com www.sciencedirect.com
    RAD52 Adjusts Repair of Single-Strand Breaks via Reducing DNA-Damage-Promoted XRCC1/LIG3α Co-localization
    1
    1. scibot 22 Jan 2021
      RRID:AB_2253533

      DOI: 10.1016/j.celrep.2020.108625

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    sciencedirect.com/science/article/pii/S2211124720316144
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    Proteome dynamics at broken replication forks reveal a distinct ATM-directed repair response suppressing DNA double-strand break ubiquitination
    1
    1. scibot 21 Jan 2021
      RRID:AB_2253533

      DOI: 10.1016/j.molcel.2020.12.025

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    sciencedirect.com/science/article/pii/S1097276520309461
  41. Dec 2020
  42. www.sciencedirect.com www.sciencedirect.com
    TREX2 Exonuclease Causes Spontaneous Mutations and Stress-Induced Replication Fork Defects in Cells Expressing RAD51K133A
    1
    1. scibot 23 Dec 2020
      RRID:AB_2253533

      DOI: 10.1016/j.celrep.2020.108543

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    sciencedirect.com/science/article/pii/S2211124720315321
  43. Oct 2020
  44. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment
    1
    1. scibot 08 Oct 2020
      RRID:AB_2253533

      DOI: 10.1016/j.celrep.2020.108221

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    pubmed.ncbi.nlm.nih.gov/33027668/
  45. Sep 2020
  46. www.sciencedirect.com www.sciencedirect.com
    The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells
    1
    1. scibot 26 Sep 2020
      RRID:AB_2253533

      DOI: 10.1016/j.celrep.2020.107849

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    sciencedirect.com/science/article/pii/S2211124720308305
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    The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates
    1
    1. scibot 04 Sep 2020
      RRID:AB_2253533

      DOI: 10.1016/j.molcel.2020.06.015

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    sciencedirect.com/science/article/pii/S1097276520304007
  48. www.sciencedirect.com www.sciencedirect.com
    Meiosis-Specific C19orf57/4930432K21Rik/BRME1 Modulates Localization of RAD51 and DMC1 to DSBs in Mouse Meiotic Recombination
    1
    1. scibot 03 Sep 2020
      RRID:AB_2253533

      DOI: 10.1016/j.celrep.2020.107686

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    sciencedirect.com/science/article/pii/S2211124720306392
  49. Jan 2020
  50. www.sciencedirect.com www.sciencedirect.com
    PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells
    1
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      RRID:AB_2253533

      DOI: 10.1016/j.molcel.2019.10.008

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    sciencedirect.com/science/article/pii/S1097276519307683
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    The Replisome Mediates A-NHEJ Repair of Telomeres Lacking POT1-TPP1 Independently of MRN Function
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      RRID:AB_2253533

      DOI: 10.1016/j.celrep.2019.11.012

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    sciencedirect.com/science/article/pii/S2211124719314834
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    RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.molcel.2019.06.043

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    sciencedirect.com/science/article/pii/S1097276519305003
  53. www.sciencedirect.com www.sciencedirect.com
    Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium
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      DOI: 10.1016/j.celrep.2019.06.043

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    sciencedirect.com/science/article/pii/S2211124719308162
  54. www.sciencedirect.com www.sciencedirect.com
    LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL
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      DOI: 10.1016/j.ccell.2019.07.007

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    sciencedirect.com/science/article/pii/S1535610819303344
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    ATR Signaling Uncouples the Role of RAD51 Paralogs in Homologous Recombination and Replication Stress Response
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      DOI: 10.1016/j.celrep.2019.09.008

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    sciencedirect.com/science/article/pii/S2211124719311854
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    Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops
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      RRID:AB_2253533

      DOI: 10.1016/j.molcel.2019.10.026

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    sciencedirect.com/science/article/pii/S1097276519308044
  57. www.embopress.org www.embopress.org
    The p97–Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8
    1
    1. scibot 13 Jan 2020
      RRID:AB_2253533

      DOI: 10.15252/embj.2019102361

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    embopress.org/doi/10.15252/embj.2019102361
  58. www.sciencedirect.com www.sciencedirect.com
    Therapeutic Targeting of CDK12/CDK13 in Triple-Negative Breast Cancer
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    1. scibot 13 Jan 2020
      RRID:AB_2253533

      DOI: 10.1016/j.ccell.2019.09.004

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    Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair
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    Alternative Lengthening of Telomeres through Two Distinct Break-Induced Replication Pathways
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      DOI: 10.1016/j.celrep.2018.12.102

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    Human RIF1-Protein Phosphatase 1 Prevents Degradation and Breakage of Nascent DNA on Replication Stalling
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    ATR-Mediated Global Fork Slowing and Reversal Assist Fork Traverse and Prevent Chromosomal Breakage at DNA Interstrand Cross-Links
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    Histone Ubiquitination by the DNA Damage Response Is Required for Efficient DNA Replication in Unperturbed S Phase
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    The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair
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    BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency
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    SMC1α Substitutes for Many Meiotic Functions of SMC1β but Cannot Protect Telomeres from Damage
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  75. Nov 2017
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    ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks
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    RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks
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    RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis
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    A Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic Reprogramming
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    A Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic Reprogramming
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