80 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neddylation and Its Target Cullin 3 Are Essential for Adipocyte Differentiation
    1
    1. scibot 07 Nov 2024
      RRID:AB_2259616

      DOI: 10.3390/cells13191654

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    pmc.ncbi.nlm.nih.gov/articles/PMC11475318/
  3. Sep 2024
  4. link.springer.com link.springer.com
    TRPV4 Blockage Inhibits the Neurogenesis in the Adult Hippocampal Dentate Gyrus Following Pilocarpine‑Induced Status Epilepticus
    1
    1. scibot 27 Sep 2024
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      DOI: 10.1007/s12035-024-04504-x

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    link.springer.com/article/10.1007/s12035-024-04504-x
  5. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    UA influences the progression of breast cancer via the AhR/p27Kip1/cyclin E pathway
    1
    1. scibot 26 Sep 2024
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      DOI: 10.1096/fj.202400938R

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202400938R
  6. www.sciencedirect.com www.sciencedirect.com
    Zdhhc1- and Zdhhc2-mediated Gpm6a palmitoylation is essential for maintenance of mammary stem cell activity
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114762

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    sciencedirect.com/science/article/pii/S2211124724011136
  7. Aug 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRCA Status Dictates Wnt Responsiveness in Epithelial Ovarian Cancer
    1
    1. scibot 22 Aug 2024
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      DOI: 10.1158/2767-9764.CRC-24-0111

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    ncbi.nlm.nih.gov/pmc/articles/PMC11320024/
  9. Jul 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Kinome-Wide Synthetic Lethal CRISPR/Cas9 Screen Reveals That mTOR Inhibition Prevents Adaptive Resistance to CDK4/CDK6 Blockade in HNSCC
    1
    1. scibot 31 Jul 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11284272/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neddylation inhibition prevents acetaminophen-induced liver damage by enhancing the anabolic cardiolipin pathway
    1
    1. scibot 17 Jul 2024
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      DOI: 10.1016/j.xcrm.2024.101653

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    ncbi.nlm.nih.gov/pmc/articles/PMC11293357/
  12. Jun 2024
  13. link.springer.com link.springer.com
    Plexin D1 emerges as a novel target in the development of neural lineage plasticity in treatment-resistant prostate cancer
    1
    1. scibot 28 Jun 2024
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      DOI: 10.1038/s41388-024-03081-6

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    link.springer.com/article/10.1038/s41388-024-03081-6
  14. May 2024
  15. www.sciencedirect.com www.sciencedirect.com
    Molecular subtypes of neuroendocrine carcinomas: A cross-tissue classification framework based on five transcriptional regulators
    1
    1. scibot 24 May 2024
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      DOI: 10.1016/j.ccell.2024.05.002

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    sciencedirect.com/science/article/pii/S1535610824001636
  16. 52.53.155.43 52.53.155.43
    TERC promotes non-small cell lung cancer progression by facilitating the nuclear localization of TERT
    1
    1. scibot 09 May 2024
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    52.53.155.43/761c70660e3a03a822484173742c13c4c44cc6bf/PIIS2589004224010915-html.html
  17. Apr 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
    1
    1. scibot 30 Apr 2024
      RRID:AB_2259616

      DOI: 10.1016/j.celrep.2024.113924

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    ncbi.nlm.nih.gov/pmc/articles/PMC11025316/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Plexin D1 emerges as a novel target in the development of neural lineage plasticity in treatment-resistant prostate cancer
    1
    1. scibot 18 Apr 2024
      RRID:AB_2259616

      DOI: 10.21203/rs.3.rs-4095949/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10996809/
  20. Mar 2024
  21. www.nature.com www.nature.com
    Colorectal cancer cells secreting DKK4 transform fibroblasts to promote tumour metastasis
    1
    1. scibot 26 Mar 2024
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      DOI: 10.1038/s41388-024-03008-1

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    nature.com/articles/s41388-024-03008-1
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
    2
    1. scibot 21 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113924

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    2. scibot 21 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113924

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    ncbi.nlm.nih.gov/pmc/articles/PMC11025316/
  23. www.sciencedirect.com www.sciencedirect.com
    Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice
    2
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113875

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      DOI: 10.1016/j.celrep.2024.113875

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    sciencedirect.com/science/article/pii/S2211124724002031
  24. Feb 2024
  25. www.sciencedirect.com www.sciencedirect.com
    Sphingolipid metabolism controls mammalian heart regeneration
    1
    1. scibot 21 Feb 2024
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      DOI: 10.1016/j.cmet.2024.01.017

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    sciencedirect.com/science/article/pii/S1550413124000172
  26. Jan 2024
  27. www.sciencedirect.com www.sciencedirect.com
    Mechanism of GW117 antidepressant action: melatonin receptor-mediated regulation of sleep rhythm
    1
    1. scibot 06 Jan 2024
      RRID:AB_2259616

      DOI: 10.1016/j.ejphar.2023.176299

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    sciencedirect.com/science/article/pii/S0014299923008130
  28. Dec 2023
  29. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation
    1
    1. scibot 29 Dec 2023
      RRID:AB_2259616

      DOI: 10.1002/advs.202305620

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    onlinelibrary.wiley.com/doi/10.1002/advs.202305620
  30. Nov 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Lidocaine induces apoptosis in head and neck squamous cell carcinoma through activation of bitter taste receptor T2R14
    1
    1. scibot 28 Nov 2023
      RRID:AB_2259616

      DOI: 10.1016/j.celrep.2023.113437

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    sciencedirect.com/science/article/pii/S2211124723014493
  32. www.sciencedirect.com www.sciencedirect.com
    Pan-cancer tRNA-derived fragment CAT1 coordinates RBPMS to stabilize NOTCH2 mRNA to promote tumorigenesis
    1
    1. scibot 17 Nov 2023
      RRID:AB_2259616

      DOI: 10.1016/j.celrep.2023.113408

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    sciencedirect.com/science/article/pii/S2211124723014201
  33. Aug 2023
  34. www.science.org www.science.org
    A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis
    1
    1. scibot 29 Aug 2023
      RRID:AB_2259616

      DOI: 10.1126/scisignal.ade6737

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    science.org/doi/10.1126/scisignal.ade6737
  35. Jul 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer
    1
    1. scibot 14 Jul 2023
      RRID:AB_2259616

      DOI: 10.1016/j.xcrm.2023.101120

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    sciencedirect.com/science/article/pii/S2666379123002483
  37. May 2023
  38. www.sciencedirect.com www.sciencedirect.com
    Modeling breast cancer proliferation, drug synergies, and alternating therapies
    1
    1. scibot 19 May 2023
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      DOI: 10.1016/j.isci.2023.106714

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    sciencedirect.com/science/article/pii/S2589004223007915
  39. www.sciencedirect.com www.sciencedirect.com
    KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells
    1
    1. scibot 05 May 2023
      RRID:AB_2259616

      DOI: 10.1016/j.celrep.2022.111077

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    sciencedirect.com/science/article/pii/S2211124722008750
  40. Feb 2023
  41. aacrjournals.org aacrjournals.org
    Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells
    1
    1. scibot 18 Feb 2023
      RRID: AB_2259616

      DOI: 10.1158/1541-7786.MCR-21-1000

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    aacrjournals.org/mcr/article/20/12/1785/710999/Loss-of-VOPP1-Contributes-to-BET-Inhibitor
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Goji berry (Lycium barbarum) inhibits the proliferation, adhesion, and migration of oral cancer cells by inhibiting the ERK, AKT, and CyclinD cell signaling pathways: an in-vitro study
    1
    1. scibot 10 Feb 2023
      RRID: AB_2259616

      DOI: 10.12688/f1000research.129250.2

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    ncbi.nlm.nih.gov/pmc/articles/PMC9887205/
  43. www.sciencedirect.com www.sciencedirect.com
    Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    1
    1. scibot 03 Feb 2023
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      DOI: 10.1016/j.molcel.2023.01.015

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    sciencedirect.com/science/article/pii/S1097276523000382
  44. Jan 2023
  45. www.sciencedirect.com www.sciencedirect.com
    Plakophilin 3 facilitates G1/S phase transition and enhances proliferation by capturing RB protein in the cytoplasm and promoting EGFR signaling
    1
    1. scibot 24 Jan 2023
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      DOI: 10.1016/j.celrep.2023.112031

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    sciencedirect.com/science/article/pii/S2211124723000426
  46. Nov 2022
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intracellular TMEM16A is necessary for myogenesis of skeletal muscle
    1
    1. scibot 17 Nov 2022
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      DOI: 10.1016/j.isci.2022.105446

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    ncbi.nlm.nih.gov/pmc/articles/PMC9647518/
  48. www.sciencedirect.com www.sciencedirect.com
    Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis
    1
    1. scibot 05 Nov 2022
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      DOI: 10.1016/j.ebiom.2022.104312

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    sciencedirect.com/science/article/pii/S2352396422004947
  49. Sep 2022
  50. www.sciencedirect.com www.sciencedirect.com
    TGF-β generates a population of cancer cells residing in G1 phase with high motility and metastatic potential via KRTAP2-3
    1
    1. scibot 29 Sep 2022
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      DOI: 10.1016/j.celrep.2022.111411

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    sciencedirect.com/science/article/pii/S2211124722012529
  51. Aug 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways
    1
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      DOI: 10.1016/j.celrep.2022.111181

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    sciencedirect.com/science/article/pii/S2211124722009949
  53. Jul 2022
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficacy of Combined Use of Everolimus and Second-Generation Pan-EGRF Inhibitors in KRAS Mutant Non-Small Cell Lung Cancer Cell Lines
    1
    1. scibot 31 Jul 2022
      RRID:AB_2259616

      DOI: 10.3390/ijms23147774

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    ncbi.nlm.nih.gov/pmc/articles/PMC9317664/
  55. www.sciencedirect.com www.sciencedirect.com
    GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment
    1
    1. scibot 15 Jul 2022
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      DOI: 10.1016/j.cmet.2022.06.010

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    sciencedirect.com/science/article/pii/S1550413122002303
  56. Mar 2022
  57. www.sciencedirect.com www.sciencedirect.com
    Moderate heart rate reduction promotes cardiac regeneration through stimulation of the metabolic pattern switch
    1
    1. scibot 09 Mar 2022
      RRID:AB_2259616

      DOI: 10.1016/j.celrep.2022.110468

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    sciencedirect.com/science/article/pii/S2211124722002017
  58. Dec 2021
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2
    1
    1. scibot 17 Dec 2021
      RRID:AB_2259616

      DOI: 10.7554/eLife.70691

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    ncbi.nlm.nih.gov/pmc/articles/PMC8670743/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Halofuginone Sensitizes Lung Cancer Organoids to Cisplatin via Suppressing PI3K/AKT and MAPK Signaling Pathways
    1
    1. scibot 11 Dec 2021
      RRID:AB_2259616

      DOI: 10.3389/fcell.2021.773048

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    ncbi.nlm.nih.gov/pmc/articles/PMC8652204/
  61. Oct 2021
  62. mct.aacrjournals.org mct.aacrjournals.org
    Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma
    1
    1. scibot 20 Oct 2021
      RRID:AB_2259616

      DOI: 10.1158/1535-7163.MCT-20-1126

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  63. www.sciencedirect.com www.sciencedirect.com
    Proteome-wide mapping of short-lived proteins in human cells
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      RRID:AB_2259616

      DOI: 10.1016/j.molcel.2021.09.015

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  64. Sep 2021
  65. www.sciencedirect.com www.sciencedirect.com
    Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells
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      RRID:AB_2259616

      DOI: 10.1016/j.celrep.2021.109639

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  66. Aug 2021
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      RRID:AB_2259616

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  68. Jul 2021
  69. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      2978

      DOI: 10.1111/bph.15434

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  70. link.springer.com link.springer.com
    RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway
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      cyclin D1

      DOI: 10.1186/s40659-019-0268-x

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  71. www.sciencedirect.com www.sciencedirect.com
    Midkine promotes articular chondrocyte proliferation through the MK-LRP1-nucleolin signaling pathway
    1
    1. scibot 31 Jul 2021
      rabbit anti-cyclin D1 monoclonal antibody

      DOI: 10.1016/j.cellsig.2019.109423

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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      RRID:AB_2259616

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  73. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SARNP, a participant in mRNA splicing and export, negatively regulates E‐cadherin expression via interaction with pinin
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      cyclin D1

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  74. Jun 2021
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular docking-aided identification of small molecule inhibitors targeting β-catenin-TCF4 interaction
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      RRID:AB_2259616

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  76. May 2021
  77. www.sciencedirect.com www.sciencedirect.com
    Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK
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  78. www.sciencedirect.com www.sciencedirect.com
    Proline Hydroxylation Primes Protein Kinases for Autophosphorylation and Activation
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      DOI: 10.1016/j.molcel.2020.06.021

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    Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer
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  80. Feb 2021
  81. www.sciencedirect.com www.sciencedirect.com
    Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1
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      RRID:AB_2259616

      DOI: 10.1016/j.celrep.2021.108749

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  82. Jan 2021
  83. link.springer.com link.springer.com
    A novel ligand of the translationally controlled tumor protein (TCTP) identified by virtual drug screening for cancer differentiation therapy
    1
    1. scibot 28 Jan 2021
      RRID:AB_2259616

      DOI: 10.1007/s10637-020-01042-w

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  84. Nov 2020
  85. link.springer.com link.springer.com
    p75NTR Promotes Astrocyte Proliferation in Response to Cortical Stab Wound
    1
    1. scibot 25 Nov 2020
      anti-Cyclin D1

      DOI: 10.1007/s10571-020-01006-x

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  86. Oct 2020
  87. www.sciencedirect.com www.sciencedirect.com
    A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis
    1
    1. scibot 27 Oct 2020
      RRID:AB_2259616

      DOI: 10.1016/j.celrep.2020.108284

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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis
    1
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      DOI: 10.7554/eLife.59442

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  89. Sep 2020
  90. www.sciencedirect.com www.sciencedirect.com
    Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation
    1
    1. scibot 25 Sep 2020
      RRID:AB_2259616

      DOI: 10.1016/j.celrep.2019.12.075

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  91. onlinelibrary.wiley.com onlinelibrary.wiley.com
    KIF15 promotes the evolution of gastric cancer cells through inhibition of reactive oxygen species‐mediated apoptosis
    1
    1. scibot 14 Sep 2020
      RRID:AB_2259616

      DOI: 10.1002/jcp.29743

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  92. www.sciencedirect.com www.sciencedirect.com
    Suppression of Membranous LRP5 Recycling, Wnt/β-Catenin Signaling, and Colon Carcinogenesis by 15-LOX-1 Peroxidation of Linoleic Acid in PI3P
    1
    1. scibot 09 Sep 2020
      RRID:AB_2259616

      DOI: 10.1016/j.celrep.2020.108049

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  93. www.sciencedirect.com www.sciencedirect.com
    Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR
    1
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      AB_2259616

      DOI: 10.1016/j.celrep.2020.107571

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  94. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Long noncoding RNA SOX2OT promotes the proliferation of pancreatic cancer by binding to FUS
    1
    1. scibot 04 Sep 2020
      CCND1

      DOI: 10.1002/ijc.32827

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  95. www.sciencedirect.com www.sciencedirect.com
    GATA-4, a potential novel therapeutic target for high-grade meningioma, regulates miR-497, a potential novel circulating biomarker for high-grade meningioma
    1
    1. scibot 03 Sep 2020
      anti-Cyclin D1

      DOI: 10.1016/j.ebiom.2020.102941

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    sciencedirect.com/science/article/pii/S2352396420303170
  96. Jan 2020
  97. www.sciencedirect.com www.sciencedirect.com
    Identification of a Small Compound Targeting PKM2-Regulated Signaling Using 2D Gel Electrophoresis-Based Proteome-wide CETSA
    1
    1. scibot 13 Jan 2020
      RRID:AB_2259616

      DOI: 10.1016/j.chembiol.2019.11.010

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  98. onlinelibrary.wiley.com onlinelibrary.wiley.com
    MicroRNA‐487a‐3p functions as a new tumor suppressor in prostate cancer by targeting CCND1
    1
    1. scibot 13 Jan 2020
      AB_10839128

      DOI: 10.1002/jcp.29078

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  99. academic.oup.com academic.oup.com
    Synergistic Highly Potent Targeted Drug Combinations in different Pheochromocytoma Models including Human Tumor Cultures
    1
    1. scibot 13 Jan 2020
      RRID:AB_2259616

      DOI: 10.1210/en.2019-00410

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  100. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_2259616

      DOI: 10.1016/j.chembiol.2019.03.012

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  101. www.sciencedirect.com www.sciencedirect.com
    Shortening the Half-Life of Cas9 Maintains Its Gene Editing Ability and Reduces Neuronal Toxicity
    1
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      RRID:AB_2259616

      DOI: 10.1016/j.celrep.2018.11.019

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  102. elifesciences.org elifesciences.org
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      RRID:AB_2259616

      DOI: 10.7554/eLife.40396

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  103. www.sciencedirect.com www.sciencedirect.com
    De Novo PITX1 Expression Controls Bi-Stable Transcriptional Circuits to Govern Self-Renewal and Differentiation in Squamous Cell Carcinoma
    1
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      RRID:AB_2259616

      DOI: 10.1016/j.stem.2019.01.003

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  104. Nov 2018
  105. www.sciencedirect.com www.sciencedirect.com
    Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC
    1
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      RRID:AB_2259616

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  106. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Testosterone regulates myosin II isoforms expression and functional activity in the rat prostate
    1
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      AB_2259616

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  107. www.sciencedirect.com www.sciencedirect.com
    PAF-Myc-Controlled Cell Stemness Is Required for Intestinal Regeneration and Tumorigenesis
    1
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      RRID:AB_10839128

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    NRF1 Is an ER Membrane Sensor that Is Central to Cholesterol Homeostasis
    1
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    Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas
    1
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  110. academic.oup.com academic.oup.com
    Canonical Wnt/β-Catenin Signaling Regulates Postnatal Mouse Epididymal Development But Does Not Affect Epithelial Cell Differentiation
    1
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      AB_2259616

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  111. Nov 2017
  112. www.sciencedirect.com www.sciencedirect.com
    Differential Wnt signaling activity limits epithelial gland development to the anti-mesometrial side of the mouse uterus - ScienceDirect
    1
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      Cyclin D1 (1:100, 2978, Cell Signaling Technology: CST

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  113. www.jneurosci.org www.jneurosci.org
    TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway
    1
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      AB_2259616

      Curator: @Zeljana_Babic

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  114. academic.oup.com academic.oup.com
    Maternal Low Protein Isocaloric Diet Suppresses Pancreatic β-Cell Proliferation in Mouse Offspring via miR-15b
    1
    1. scibot 08 Nov 2017
      Cell Signalling Technology; number 2978 

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      RRID:AB_2259616
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    academic.oup.com/endo/article/157/12/4782/2758433/Maternal-Low-Protein-Isocaloric-Diet-Suppresses
  115. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The antiviral cytokine interferon‐gamma restricts neural stem/progenitor cell proliferation through activation of STAT1 and modulation of retinoblastoma protein phosphorylation
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    1. scibot 08 Nov 2017
      AB_2259616

      Curator: @chewbeccax

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      (Cell Signaling Technology Cat# 2978, RRID:AB_2259616)

      SciCrunch record: RRID:AB_2259616

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      RRID:AB_2259616
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    onlinelibrary.wiley.com/doi/10.1002/jnr.23987/full