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Multiomic characterization of microsatellite-stable colorectal cancer reveals distinct biology and targetable vulnerabilities

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sciencedirect.com/science/article/pii/S1535610826004332
Aug 2026
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Periostin drives psoriasis progression through the stimulation of cutaneous nerve fibers

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JI017 Sensitizes EGFR-T790M NSCLC to Erlotinib by Extinguishing the STAT3–Survivin Axis

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BPS Publications

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  DOI: 10.1111/bph.15472
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15472
Jul 2026
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Trans-synaptic signaling through GRID1/glutamate receptor delta-1 and CBLN1/cerebellin-1 facilitates autophagic flux in central amygdala and prevents chronic pain

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pmc.ncbi.nlm.nih.gov/articles/PMC12758341/
May 2026
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Maternal hyperglycemia disrupts cardiomyocyte maturation via aberrant nucleotide metabolism and suppression of AMPK signaling

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sciencedirect.com/science/article/pii/S2211124726003992
Mar 2026
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Targeting the ferritinophagy-lysosome axis as a therapeutic vulnerability in gastroenteropancreatic neuroendocrine tumors

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sciencedirect.com/science/article/pii/S2666379126001126
Jan 2026
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Blood-flow restriction resistance training improves skeletal muscle mitochondrial capacity and cardiovascular risk factors in type 2 diabetes

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sciencedirect.com/science/article/pii/S1550413125005479
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Metabolic reprogramming during human neuron differentiation indicates glutaminase as a key determinant in Fragile X syndrome

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sciencedirect.com/science/article/pii/S2211124725016298
Dec 2025
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BPS Publications

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  DOI: 10.1111/bph.70258
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70258
Jul 2025
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The planar cell polarity (PCP) protein Fat 1 in Sertoli cell function

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  DOI: 10.1210/endocr/bqae041
  
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dx.doi.org/10.1210/endocr/bqae041
Mar 2025
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Cytotoxic Autophagy: A Novel Treatment Paradigm against Breast Cancer Using Oleanolic Acid and Ursolic Acid

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  DOI: 10.3390/cancers16193367
  
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mdpi.com/2072-6694/16/19/3367
Dec 2024
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The cGAS-STING pathway activates transcription factor TFEB to stimulate lysosome biogenesis and pathogen clearance

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1. scibot 17 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.017
  
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sciencedirect.com/science/article/pii/S1074761324005326
Nov 2024
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Lysosomal damage triggers a p38 MAPK-dependent phosphorylation cascade to promote lysophagy via the small heat shock protein HSP27

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1. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.cub.2024.10.061
  
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sciencedirect.com/science/article/pii/S096098222401457X
Aug 2024
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Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies

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1. scibot 22 Aug 2024
  
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  DOI: 10.1016/j.cell.2020.02.019
  
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cell.com/cell/fulltext/S0092-8674(20)30163-X
Apr 2024
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12958_2024_1204_MOESM1_ESM-html.html

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1. scibot 05 Apr 2024
  
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  DOI: 10.1186/s12958-024-01204-y
  
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52.53.155.43/d3bb518aa444c98d6cfb77a0666830bf57a4ed47/12958_2024_1204_MOESM1_ESM-html.html
Mar 2024
www.biorxiv.org www.biorxiv.org

Stabilization of AMPK/PFKL/RPIA in the Glycolytic Bodies Transduces IL6/STAT3 Signal in Hepatocarcinogenesis

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1. scibot 21 Mar 2024
  
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  DOI: 10.1101/2024.02.29.582877
  
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biorxiv.org/content/10.1101/2024.02.29.582877v1
Feb 2024
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mTOR regulates mineralocorticoid receptor transcriptional activity by ULK1- dependent and independent mechanisms

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1. scibot 15 Feb 2024
  
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  DOI: 10.1210/endocr/bqae015
  
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52.53.155.43/6951e0010ae4c14df11b3315f954e81c6a9c88a4/bqae015-html.html
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Endothelial cell-specific mineralocorticoid receptor activation promotes diastolic dysfunction in diet induced obese male mice

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  DOI: 10.1152/ajpregu.00274.2021
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9799154/
Nov 2023
52.53.155.43 52.53.155.43

s11684-022-0959-5 (1)-html.html

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  DOI: 10.3389/fncel.2020.552213
  
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52.53.155.43/248247a6c473b6538a75d1aee7982a849ed2ea8a/s11684-022-0959-5 (2)-html.html
Aug 2023
52.53.155.43 52.53.155.43

PIIS2589004223017029-html.html

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52.53.155.43/258d74bd1c79cf4d725c254c0f9188b69c056c90/PIIS2589004223017029-html.html
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Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting

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ncbi.nlm.nih.gov/pmc/articles/PMC10432853/
Jul 2023
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Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cells

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  DOI: 10.1016/j.celrep.2023.112794
  
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sciencedirect.com/science/article/pii/S2211124723008057
May 2023
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s11684-022-0959-5-html.html

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1. scibot 27 May 2023
  
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  RRID:AB_2262884
  
  DOI: 10.1016/j.lungcan.2010.01.001
  
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  DOI: 10.1016/j.lungcan.2010.01.001
  
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  DOI: 10.1007/s11684-022-0959-5
  
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52.53.155.43/2a5df239930e05a1fe550ae7329d1c04600de669/s11684-022-0959-5 (1)-html.html
Jan 2023
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mTORC2 loss in oligodendrocyte progenitor cells results in regional hypomyelination in the central nervous system

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  DOI: 10.1523/JNEUROSCI.0010-22.2022
  
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pmc.ncbi.nlm.nih.gov/articles/PMC9888514/
Nov 2022
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mTOR inhibition decreases angiotensin II-induced steroidogenesis in HAC15 human adrenocortical carcinoma cells

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1. scibot 19 Nov 2022
  
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  DOI: 10.1210/endocr/bqac185
  
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academic.oup.com/endo/article/164/1/bqac185/6793711
May 2022
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Localization of a TORC1-eIF4F translation complex during CD8+ T cell activation drives divergent cell fate

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  DOI: 10.1016/j.molcel.2022.04.016
  
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sciencedirect.com/science/article/pii/S1097276522003276
Mar 2022
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Selenoprotein P-mediated reductive stress impairs cold-induced thermogenesis in brown fat

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  DOI: 10.1016/j.celrep.2022.110566
  
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sciencedirect.com/science/article/pii/S2211124722003102
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Undercarboxylated Osteocalcin Improves Insulin-Stimulated Glucose Uptake in Muscles of Corticosterone-Treated Mice

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  DOI: 10.1002/jbmr.3731
  
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asbmr.onlinelibrary.wiley.com/doi/10.1002/jbmr.3731
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F-box protein FBXO41 plays vital role in arsenic trioxide-mediated autophagic death of cancer cells

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  DOI: 10.1016/j.taap.2022.115973
  
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sciencedirect.com/science/article/pii/S0041008X22001181
Jan 2022
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mTOR inhibition impairs extinction memory reconsolidation

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  DOI: 10.1101/lm.052068.120
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7747651/
Nov 2021
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Electroconvulsive seizure inhibits the mTOR signaling pathway via AMPK in the rat frontal cortex

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1. scibot 02 Nov 2021
  
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  DOI: 10.1007/s00213-021-06015-2
  
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link.springer.com/article/10.1007/s00213-021-06015-2
Aug 2021
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Untitled document

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  DOI: 10.1016/j.celrep.2018.11.018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6302735/
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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  RRID:AB_2262884
  
  DOI: 10.1016/j.cmet.2018.08.013
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6331339/
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1. scibot 30 Jul 2021
  
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  DOI: 10.1016/j.celrep.2018.11.018
  
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Multisite Phosphorylation of S6K1 Directs a Kinase Phospho-code that Determines Substrate Selection

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1. scibot 27 Jul 2021
  
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  DOI: 10.1016/j.molcel.2018.11.017
  
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Programmed PPAR-α downregulation induces inflammaging by suppressing fatty acid catabolism in monocytes

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  DOI: 10.1016/j.isci.2021.102766
  
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Thyroid hormone receptor beta inhibits the PI3K-Akt-mTOR signaling axis in anaplastic thyroid cancer cell lines via genomic mechanisms

1
1. scibot 14 Jul 2021
  
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  DOI: 10.1210/jendso/bvab102
  
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A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes

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1. scibot 29 Apr 2021
  
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  DOI: 10.1016/j.cmet.2020.08.007
  
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Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons

1
1. scibot 28 Apr 2021
  
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  DOI: 10.1016/j.celrep.2021.109034
  
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Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer

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  DOI: 10.1016/j.chembiol.2020.06.011
  
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Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2

1
1. scibot 07 Dec 2020
  
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  DOI: 10.1016/j.molcel.2020.11.028
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7674017/
Oct 2020
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The mTORC1/S6K/PDCD4/eIF4A Axis Determines Outcome of Mitotic Arrest

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1. scibot 07 Oct 2020
  
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sciencedirect.com/science/article/pii/S2211124720312195
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Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies

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  DOI: 10.1016/j.cell.2020.02.019
  
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cell.com/cell/fulltext/S0092-8674(20)30163-X
Jan 2020
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Deletion of Fmr1 from Forebrain Excitatory Neurons Triggers Abnormal Cellular, EEG, and Behavioral Phenotypes in the Auditory Cortex of a Mouse Model of Fragile X Syndrome

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1093/cercor/bhz141
  
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academic.oup.com/cercor/advance-article-abstract/doi/10.1093/cercor/bhz141/5540232
cancerres.aacrjournals.org cancerres.aacrjournals.org

Inhibition of Dipeptidyl Peptidase-4 Accelerates Epithelial–Mesenchymal Transition and Breast Cancer Metastasis via the CXCL12/CXCR4/mTOR Axis

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1158/0008-5472.CAN-18-0620
  
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cancerres.aacrjournals.org/content/79/4/735
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12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.cmet.2019.07.001
  
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Interaction of Discoidin Domain Receptor 1 with a 14-3-3-Beclin-1-Akt1 Complex Modulates Glioblastoma Therapy Sensitivity

1
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Nov 2018
onlinelibrary.wiley.com onlinelibrary.wiley.com

Genetic Removal of eIF2α Kinase PERK in Mice Enables Hippocampal L‐LTP Independent of mTORC1 Activity

1
1. scibot 05 Nov 2018
  
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onlinelibrary.wiley.com/doi/full/10.1111/jnc.14306
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Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A

1
1. scibot 05 Nov 2018
  
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Nov 2017
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Stabilization of the c-Myc Protein by CAMKIIγ Promotes T Cell Lymphoma

1
1. scibot 08 Nov 2017
  
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