202 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    O-GlcNAcylation of circadian clock protein Bmal1 impairs cognitive function in diabetic mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11574178/
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    Netrin1 patterns the dorsal spinal cord through modulation of Bmp signaling
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    Porcine NLRC3 specially binds short dsDNA to regulate cGAS activation
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  5. Oct 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The AGEs/RAGE Signaling Pathway Regulates NLRP3-Mediated Neuronal Pyroptosis After MCAO Injury in Lepr−/− Obese Rats
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    Genetic deletion of the apoptosis associated speck like protein containing a card in LysM+ macrophages attenuates spinal cord injury by regulating M1/M2 polarization through ASC-dependent inflammasome signaling axis
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    Leucine restriction ameliorates Fusobacterium nucleatum-driven malignant progression and radioresistance in nasopharyngeal carcinoma
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    sciencedirect.com/science/article/pii/S266637912400483X
  9. Sep 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HIF‐1α knockdown attenuates inflammation and oxidative stress in ischemic stroke male rats via CXCR4/NF‐κB pathway
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    Divergent input patterns to the central lateral amygdala play a duet in fear memory formation
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    TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival
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    Conditional ablation of MCU exacerbated cardiac pathology in a genetic arrhythmic model of CPVT
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    SGLT2 inhibitor promotes ketogenesis to improve MASH by suppressing CD8+ T cell activation
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    Lipolysis engages CD36 to promote ZBP1-mediated necroptosis-impairing lung regeneration in COPD
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    Molecular basis of CX-5461-induced DNA damage response in primary vascular smooth muscle cells
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  17. Aug 2024
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    MiR-137-3p mechanisms of action and blood-brain barrier penetrating and neuron-targeting lipid nanoparticles deliver miR-137-3p for the treatment of Alzheimer's disease
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    Overexpression of microRNA-611 inhibits TGF-β-induced epithelial-mesenchymal transition and migration in lung cancer cells through MAPKAP1
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    Ubiquitin-specific peptidase 22 controls integrin-dependent cancer cell stemness and metastasis
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    Nuclear retention coupled with sequential polyadenylation dictates post-transcriptional m6A modification in the nucleus
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    Anticancer effects of Erzhimaoling decoction in high-grade serous ovarian cancer in vitro and in vivo
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    ST6GALNAC1-mediated sialylation in uterine endometrial epithelium facilitates the epithelium-embryo attachment
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    CircMAPK9 promotes adipogenesis through modulating hsa-miR-1322/FTO axis in obesity
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    NPC1 regulates the distribution of phosphatidylinositol 4-kinases at Golgi and lysosomal membranes
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  26. Jul 2024
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    Genome-scale exon perturbation screens uncover exons critical for cell fitness
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    Bombinin-BO1 induces hepatocellular carcinoma cell-cycle arrest and apoptosis via the HSP90A-Cdc37-CDK1 axis
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    ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells
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  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling
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    SWI/SNF chromatin remodeling factor BAF60b restrains inflammatory diseases by affecting regulatory T cell migration
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  32. Jun 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP36 inhibits apoptosis by deubiquitinating cIAP1 and survivin in colorectal cancer cells
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    Exosomes derived from vMIP-II-Lamp2b gene-modified M2 cells provide neuroprotection by targeting the injured spinal cord, inhibiting chemokine signals and modulating microglia/macrophage polarization in mice
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    DL-3-n-Butylphthalide Ameliorates Post-stroke Emotional Disorders by Suppressing Neuroinflammation and PANoptosis
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  36. May 2024
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LncRNA IRAIN overcomes imatinib resistance in chronic myeloid leukemia via NF-κB/CD44 pathway inhibition
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  38. www.biorxiv.org www.biorxiv.org
    IFIT1 is rapidly evolving and exhibits disparate antiviral activities across 11 mammalian orders
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    Intersectin1 promotes clathrin-mediated endocytosis by organizing and stabilizing endocytic protein interaction networks
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    Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia
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    Single-cell transcriptomic analysis of decidual immune cell landscape in the occurrence of adverse pregnancy outcomes induced by Toxoplasma gondii infection
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    USP7 promotes IgA class switching through stabilizing RUNX3 for germline transcription activation
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    Positive and negative feedback regulation of the TGF-β1 explains two equilibrium states in skin aging
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    AdipoRon promotes amyloid-β clearance through enhancing autophagy via nuclear GAPDH-induced sirtuin 1 activation in Alzheimer's disease
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    A dynamin superfamily-like pseudoenzyme coordinates with MICOS to promote cristae architecture
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  46. Apr 2024
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    Candesartan upregulates angiotensin-converting enzyme 2 in kidneys of male animals by decreased ubiquitination
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    Ubiquitin ligase TRIM15 promotes the progression of pancreatic cancer via the upregulation of the IGF2BP2-TLR4 axis
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    hnRNPU is required for spermatogonial stem cell pool establishment in mice
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    Islet resident macrophage-derived miR-155 promotes β-cell decompensation via targeting PDX1
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    Characterization of novel PHEX variants in X-linked hypophosphatemic rickets and genotype-PHEX activity correlation
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    Aging-induced tRNAGlu-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization
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    Dietary elaidic acid boosts tumoral antigen presentation and cancer immunity via ACSL5
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    Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells
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  68. Jan 2024
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    ZFP281 controls transcriptional and epigenetic changes promoting mouse pluripotent state transitions via DNMT3 and TET1
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  73. Dec 2023
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    Translocation of telomerase reverse transcriptase coincided with ATP release in postnatal cochlear supporting cells
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    Preclinical characterization of danatinib as a novel FLT3 inhibitor with excellent efficacy against resistant acute myeloid leukemia
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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteostasis is differentially modulated by inhibition of translation initiation or elongation
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    The Effects of Chronic Unpredictable Mild Stress and Semi-Pure Diets on the Brain, Gut and Adrenal Medulla in C57BL6 Mice
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    Phosphoribosyl-linked serine ubiquitination of USP14 by the SidE family effectors of Legionella excludes p62 from the bacterial phagosome
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    Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice
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    R17C Mutation in Photoreceptor Disc-Specific Protein, PRCD, Results in Additional Lipidation Altering Protein Stability and Subcellular Localization
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  184. Nov 2021
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  186. Oct 2021
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    Deficiency of ER Ca2+ sensor STIM1 in AgRP neurons confers protection against dietary obesity
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    PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation
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  189. Sep 2021
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    The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation
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    Clemastine Fumarate Attenuates Myocardial Ischemia Reperfusion Injury Through Inhibition of Mast Cell Degranulation
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  192. Aug 2021
  193. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ponesimod protects against neuronal death by suppressing the activation of A1 astrocytes in early brain injury after experimental subarachnoid hemorrhage
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  194. Jul 2021
  195. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Activation of spinal PDGFRβ in microglia promotes neuronal autophagy via p38 MAPK pathway in morphine-tolerant rats
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  197. elifesciences.org elifesciences.org
    USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication
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      Rabbit Polyclonal Anti-GAPDH Antibody

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    Glycerol-3-phosphate biosynthesis regenerates cytosolic NAD+ to alleviate mitochondrial disease
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    W246G Mutant ELOVL4 Impairs Synaptic Plasticity in Parallel and Climbing Fibers and Causes Motor Defects in a Rat Model of SCA34
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  200. Jun 2021
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    Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation
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  202. May 2021
  203. journals.sagepub.com journals.sagepub.com
    Human Umbilical Cord Mesenchymal Stem Cells-Secreted TSG-6 Is Anti-Inflammatory and Promote Tissue Repair After Spinal Cord Injury - Ziling Liao, Wei Wang, Weiyue Deng, Yuying Zhang, Aishi Song, Sihao Deng, Huifang Zhao, Shusheng Zhang, Zhiyuan Li, 2021
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  205. Apr 2021
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    Social context-dependent singing alters molecular markers of synaptic plasticity signaling in finch basal ganglia Area X
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  207. Mar 2021
  208. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrative identification of the pathogenic role of a novel G6PD missense mutation c.697G>C
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  209. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pin1 Promotes NLRP3 Inflammasome Activation by Phosphorylation of p38 MAPK Pathway in Septic Shock
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    In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs
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    Transcription of MRPL12 regulated by Nrf2 contributes to the mitochondrial dysfunction in diabetic kidney disease
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    An integrated network pharmacology and transcriptomic method to explore the mechanism of the total Rhizoma Coptidis alkaloids in improving diabetic nephropathy
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  214. Feb 2021
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    Structure of the catalytic core of the Integrator complex
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  216. Jan 2021
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    Protective effect of hydrogen sulfide on endothelial cells through Sirt1-FoxO1-mediated autophagy
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  218. Dec 2020
  219. link.springer.com link.springer.com
    Overexpression of thioredoxin reductase 1 can reduce DNA damage, mitochondrial autophagy and endoplasmic reticulum stress in Parkinson's disease
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      GAPDH

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  220. Sep 2020
  221. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      DOI: 10.1111/bph.14912

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    Herpes Simplex Virus 1-Induced Blood-Brain Barrier Damage Involves Apoptosis Associated With GM130-Mediated Golgi Stress
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      RRID:AB_2263076

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    RACGAP1 is transcriptionally regulated by E2F3, and its depletion leads to mitotic catastrophe in esophageal squamous cell carcinoma
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    Wdr47 Controls Neuronal Polarization through the Camsap Family Microtubule Minus-End-Binding Proteins
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    A novel function of R-spondin1 in regulating estrogen receptor expression independent of Wnt/β-catenin signaling
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  227. onlinelibrary.wiley.com onlinelibrary.wiley.com
    microRNA‐9‐5p alleviates blood‐brain barrier damage and neuroinflammation after traumatic brain injury
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      rabbit anti‐GAPDH

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  229. Jan 2020
  230. www.sciencedirect.com www.sciencedirect.com
    Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation
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    In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8–16-mer Oligomer Species
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    PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways
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      RRID:AB_2263076

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    Biglycan Regulates Neuroinflammation by Promoting M1 Microglial Activation in Early Brain Injury after Experimental Subarachnoid Hemorrhage
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      DOI: 10.1111/jnc.14926

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  234. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      RRID:AB_2263076

      DOI: 10.1016/j.bbr.2018.12.004

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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0166432818312336
  236. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      RRID:AB_2263076

      DOI: 10.7554/eLife.42426

      Resource: (Proteintech Cat# 10494-1-AP, RRID:AB_2263076)

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC6361614/
  237. Nov 2018
  238. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Antagonizing peroxisome proliferator‐activated receptor γ facilitates M1‐to‐M2 shift of microglia by enhancing autophagy via the LKB1–AMPK signaling pathway
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      Curator: @anp055

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    onlinelibrary.wiley.com/doi/full/10.1111/acel.12774
  239. elifesciences.org elifesciences.org
    SPIN1 promotes tumorigenesis by blocking the uL18 (universal large ribosomal subunit protein 18)-MDM2-p53 pathway in human cancer
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      Curator: @evieth

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    elifesciences.org/articles/31275
  240. europepmc.org europepmc.org
    Zfp281 is essential for mouse epiblast maturation through transcriptional and epigenetic control of Nodal signaling
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    1. scibot 05 Nov 2018
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      Curator: @evieth

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      (Proteintech Group Cat# 10494-1-AP, RRID:AB_2263076)

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      RRID:AB_2263076 RRIDCUR:Validated
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    europepmc.org/articles/PMC5708896/