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54.241.53.176 54.241.53.176

2026.02.11.705361v1.full-html.html

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1. scibot 19 Feb 2026
  
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  RRID:AB_2280448
  
  DOI: 10.64898/2026.02.11.705361
  
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54.241.53.176/5c618bd82011554652ee37be2d6b5f0590a656fa/2026.02.11.705361v1.full-html.html
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Identifying antisense oligonucleotides for targeted inhibition of insulin receptor isoform A

1
1. scibot 21 May 2025
  
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  DOI: 10.3389/fonc.2025.1563985
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12038057/
Apr 2025
52.53.155.43 52.53.155.43

1-s2.0-S2212877825000584-main-html.html

1
1. scibot 19 Apr 2025
  
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  RRID:AB_2280448
  
  DOI: 10.1016/j.molmet.2025.102151
  
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52.53.155.43/284b8517565b9764dbe5c0470f72829f488a110b/1-s2.0-S2212877825000584-main-html.html
www.sciencedirect.com www.sciencedirect.com

Ceramide-induced FGF13 impairs systemic metabolic health

1
1. scibot 01 Apr 2025
  
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  RRID:AB_2280448
  
  DOI: 10.1016/j.cmet.2025.03.002
  
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sciencedirect.com/science/article/pii/S1550413125001056
Mar 2025
52.53.155.43 52.53.155.43

PDF-html.html

2
1. scibot 25 Mar 2025
  
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  RRID:AB_2280448
  
  DOI: 10.1210/endocr/bqaf051
  
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2. scibot 24 Mar 2025
  
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  RRID:AB_2280448
  
  DOI: 10.1210/endocr/bqaf051
  
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52.53.155.43/53309e2192e51912992203fea9560cdb3f219267/bqaf051-html.html
biosignaling.biomedcentral.com biosignaling.biomedcentral.com

Emerging role of IGF1R and IR expression and localisation in adrenocortical carcinomas

1
1. scibot 06 Mar 2025
  
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  RRID: AB_2280448
  
  DOI: 10.1186/s12964-025-02115-0
  
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biosignaling.biomedcentral.com/articles/10.1186/s12964-025-02115-0
Feb 2025
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Leptin enhances the intracellular thyroid hormone activation in skeletal muscle to boost energy balance

1
1. scibot 25 Feb 2025
  
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  DOI: 10.1016/j.cmet.2025.01.025
  
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sciencedirect.com/science/article/pii/S1550413125000257
dx.doi.org dx.doi.org

The roles of Growth Hormone dependent JAK-STAT5 and Lyn kinase signalling in determining lifespan and cancer incidence

1
1. scibot 20 Feb 2025
  
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  AB_2280448
  
  DOI: 10.1210/endocr/bqae136
  
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dx.doi.org/10.1210/endocr/bqae136
Dec 2024
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FcRn-dependent IgG accumulation in adipose tissue unmasks obesity pathophysiology

1
1. scibot 19 Dec 2024
  
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  RRID:AB_2280448
  
  DOI: 10.1016/j.cmet.2024.11.001
  
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sciencedirect.com/science/article/pii/S1550413124004479
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DEP-1 is a brain insulin receptor phosphatase that prevents the simultaneous activation of counteracting metabolic pathways

1
1. scibot 02 Dec 2024
  
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  RRID:AB_2280448
  
  DOI: 10.1016/j.celrep.2024.114984
  
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sciencedirect.com/science/article/pii/S2211124724013354
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Proteolethargy is a pathogenic mechanism in chronic disease

1
1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.cell.2024.10.051
  
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sciencedirect.com/science/article/pii/S0092867424012741
Sep 2024
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Ceramide synthesis inhibitors prevent lipid-induced insulin resistance through the DAG-PKCε-insulin receptorT1150 phosphorylation pathway

1
1. scibot 25 Sep 2024
  
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  AB_2280448
  
  DOI: 10.1016/j.celrep.2024.114746
  
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sciencedirect.com/science/article/pii/S2211124724010970
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m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1

1
1. scibot 10 Sep 2024
  
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  RRID:AB_2280448
  
  DOI: 10.1016/j.cmet.2024.08.006
  
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sciencedirect.com/science/article/pii/S1550413124003334
Jul 2024
dx.doi.org dx.doi.org

Cenicriviroc Suppresses and Reverses Steatohepatitis by Regulating Macrophage Infiltration and M2 Polarization in Mice

1
1. scibot 18 Jul 2024
  
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  AB_2280448
  
  DOI: 10.1210/endocr/bqae069
  
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dx.doi.org/10.1210/endocr/bqae069
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Multi-step regulation of microRNA expression and secretion into small extracellular vesicles by insulin

1
1. scibot 16 Jul 2024
  
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  AB_2280448
  
  DOI: 10.1016/j.celrep.2024.114491
  
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sciencedirect.com/science/article/pii/S2211124724008209
Jun 2024
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Insulin and leptin oscillations license food-entrained browning and metabolic flexibility

1
1. scibot 21 Jun 2024
  
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  RRID:AB_2280448
  
  DOI: 10.1016/j.celrep.2024.114390
  
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sciencedirect.com/science/article/pii/S2211124724007186
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Contrasting consequences of podocyte IGF1R inhibition

1
1. scibot 09 May 2024
  
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  RRID:AB_2280448
  
  DOI: 10.1016/j.isci.2024.109749
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11068853/
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Islet resident macrophage-derived miR-155 promotes β-cell decompensation via targeting PDX1

1
1. scibot 11 Apr 2024
  
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  RRID:AB_2280448
  
  DOI: 10.1016/j.isci.2024.109540
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10993184/
Nov 2023
www.sciencedirect.com www.sciencedirect.com

HOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway by regulating MSK1 and PPP2R2B

1
1. scibot 17 Nov 2023
  
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  RRID:AB_2280448
  
  DOI: 10.1016/j.xcrm.2023.101285
  
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sciencedirect.com/science/article/pii/S2666379123004792
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hippocampus Insulin Receptors Regulate Episodic and Spatial Memory Through Excitatory/Inhibitory Balance

3
1. scibot 09 Nov 2023
  
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  RRID:AB_2280448
  
  DOI: 10.1177/17590914231206657
  
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2. scibot 09 Nov 2023
  
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  RRID:AB_2280448
  
  DOI: 10.1177/17590914231206657
  
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3. scibot 09 Nov 2023
  
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  RRID:AB_2280448
  
  DOI: 10.1177/17590914231206657
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10621302/
Sep 2023
dx.doi.org dx.doi.org

Insulin Signaling Is Preserved in Skeletal Muscle During Early Diabetic Ketoacidosis

1
1. scibot 14 Sep 2023
  
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  AB_2280448
  
  DOI: 10.1210/clinem/dgad464
  
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dx.doi.org/10.1210/clinem/dgad464
Aug 2023
www.sciencedirect.com www.sciencedirect.com

PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate

1
1. scibot 11 Aug 2023
  
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  RRID:AB_2280448
  
  DOI: 10.1016/j.molcel.2023.07.015
  
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sciencedirect.com/science/article/pii/S1097276523005580
Jul 2023
dx.doi.org dx.doi.org

Pigment Epithelium-Derived Factor, a Novel Adipokine, Contributes to Gestational Diabetes Mellitus

1
1. scibot 29 Jul 2023
  
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  RRID:AB_2280448
  
  DOI: 10.1210/clinem/dgad413
  
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dx.doi.org/10.1210/clinem/dgad413
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mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching

1
1. scibot 27 Jul 2023
  
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  RRID:AB_2280448
  
  DOI: 10.1016/j.celrep.2023.112868
  
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sciencedirect.com/science/article/pii/S2211124723008793
52.53.155.43 52.53.155.43

PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate

1
1. scibot 18 Jul 2023
  
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  RRID:AB_2280448
  
  DOI: 10.1101/2023.05.18.541123
  
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52.53.155.43/47cafcf0b0c101b9655865f446b83a64cc86d1a1/2023.05.18.541123v1.full-html.html
May 2023
www.nature.com www.nature.com

Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease

1
1. scibot 06 May 2023
  
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  RRID:AB_2280448
  
  DOI: 10.1038/s41467-023-38165-6
  
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nature.com/articles/s41467-023-38165-6
Apr 2023
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CD36 regulates diurnal glucose metabolism and hepatic clock to maintain glucose homeostasis in mice

1
1. scibot 23 Apr 2023
  
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  RRID:AB_2280448
  
  DOI: 10.1016/j.isci.2023.106524
  
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sciencedirect.com/science/article/pii/S2589004223006016
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma

1
1. scibot 05 Mar 2023
  
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  RRID:AB_2280448
  
  DOI: 10.1158/1541-7786.MCR-22-0090
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9444924/
Jan 2023
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SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2

1
1. scibot 12 Jan 2023
  
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  RRID:AB_2280448
  
  DOI: 10.1016/j.celrep.2022.111984
  
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sciencedirect.com/science/article/pii/S2211124722018885
Dec 2022
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Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis

1
1. scibot 24 Dec 2022
  
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  RRID:AB_2280448
  
  DOI: 10.1016/j.celrep.2022.111834
  
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sciencedirect.com/science/article/pii/S2211124722017260
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Discovery of a potent allosteric activator of DGKQ that ameliorates obesity-induced insulin resistance via the sn-1,2-DAG-PKCε signaling axis

1
1. scibot 17 Dec 2022
  
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  RRID:AB_2280448
  
  DOI: 10.1016/j.cmet.2022.11.012
  
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sciencedirect.com/science/article/pii/S1550413122005034
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The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC

1
1. scibot 08 Dec 2022
  
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  RRID:AB_2280448
  
  DOI: 10.1016/j.celrep.2022.111759
  
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sciencedirect.com/science/article/pii/S2211124722016424
Nov 2022
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Simultaneous SGLT2 inhibition and caloric restriction improves insulin resistance and kidney function in OLETF rats

1
1. scibot 03 Nov 2022
  
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  RRID:AB_2280448
  
  DOI: 10.1016/j.mce.2022.111811
  
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sciencedirect.com/science/article/pii/S0303720722002593
Aug 2022
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Deletion of serine racemase reverses neuronal insulin signaling inhibition by amyloid-β oligomers

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Icariin ameliorates memory deficits through regulating... : Neural Regeneration Research

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Hypothalamic miR-1983 targets insulin receptor beta and the insulin-mediated miR-1983 increase is blocked by metformin

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TOX4, an insulin receptor-independent regulator of hepatic glucose production, is activated in diabetic liver

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A MET-PTPRK kinase-phosphatase rheostat controls ZNRF3 and Wnt signaling

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Neuronal XRN1 is required for maintenance of whole-body metabolic homeostasis

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Pericyte Insulin Receptors Modulate Retinal Vascular Remodeling and Endothelial Angiopoietin Signaling

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GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK

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Untitled document

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Renal Metabolic Programming Is Linked to the Dynamic Regulation of a Leptin-Klf15 Axis and Akt/AMPKα Signaling in Male Offspring of Obese Dams

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Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1

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Untitled document

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Lack of Lrp5 Signaling in Osteoblasts Sensitizes Male Mice to Diet-Induced Disturbances in Glucose Metabolism

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Glucose Transporter-4 Facilitates Insulin-Stimulated Glucose Uptake in Osteoblasts

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Endothelial insulin receptors promote VEGF-A signaling via ERK1/2 and sprouting angiogenesis

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CX3CL1–CX3CR1 signalling deficiency exacerbates obesity-induced inflammation and insulin resistance in male mice

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Dissociation of Muscle Insulin Resistance from Alterations in Mitochondrial Substrate Preference

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A Membrane-Bound Diacylglycerol Species Induces PKCϵ-Mediated Hepatic Insulin Resistance

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The cytoskeleton actin binding protein filamin A impairs both IGF2 mitogenic effects and the efficacy of IGF1R inhibitors in adrenocortical cancer cells

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Negative regulation of AMPK signaling by high glucose via E3 ubiquitin ligase MG53

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Expression of miRNA-29 in Pancreatic β Cells Promotes Inflammation and Diabetes via TRAF3

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The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development

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Reducing NADPH Synthesis Counteracts Diabetic Nephropathy through Restoration of AMPK Activity in Type 1 Diabetic Rats

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Astroglial biotin deprivation under endoplasmic reticulum stress uncouples BCAA‐mTORC1 role in lipid synthesis to prolong autophagy inhibition in the aging brain

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Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet–induced hepatic steatosis and insulin resistance by elevating IL-18 levels

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DPP-4 inhibition with anagliptin reduces lipotoxicity-induced insulin resistance and steatohepatitis in male mice

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Lactational metformin exposure programs offspring white adipose tissue glucose homeostasis and resilience to metabolic stress in a sex-dependent manner | American Journal of Physiology-Endocrinology and Metabolism

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  monoclonal rabbit insulin receptor-β
  
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Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease

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Identification of a Paracrine Signaling Mechanism Linking CD34high Progenitors to the Regulation of Visceral Fat Expansion and Remodeling

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Hepatic nitric oxide synthase 1 adaptor protein regulates glucose homeostasis and hepatic insulin sensitivity in obese mice depending on its PDZ binding domain

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Role of hepatic glucocorticoid receptor in metabolism in models of 5αR1 Deficiency in Male Mice

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Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer

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  DOI: 10.1016/j.celrep.2019.09.004
  
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Betulinic acid alleviates endoplasmic reticulum stress‐mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice

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  DOI: 10.1016/j.cell.2019.02.030
  
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Lysosome Positioning Influences mTORC2 and AKT Signaling

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  DOI: 10.1016/j.molcel.2019.05.009
  
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Protein Kinase C Epsilon Deletion in Adipose Tissue, but Not in Liver, Improves Glucose Tolerance

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Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells

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A Loss of Epigenetic Control Can Promote Cell Death through Reversing the Balance of Pathways in a Signaling Network

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COMMD5/HCaRG Hooks Endosomes on Cytoskeleton and Coordinates EGFR Trafficking

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In Vivo Decoding Mechanisms of the Temporal Patterns of Blood Insulin by the Insulin-AKT Pathway in the Liver

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Systematic Functional Annotation of Somatic Mutations in Cancer

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Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation

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Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance

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