17 Matching Annotations
  1. Nov 2023
  2. www.sciencedirect.com www.sciencedirect.com
    Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML
    1
    1. scibot 22 Nov 2023
      RRID:AB_2281980

      DOI: 10.1016/j.xcrm.2023.101290

      Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S2666379123004846
  3. Jan 2023
  4. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Artesunate, a new antimalarial clinical drug, exhibits potent anti-AML activity by targeting the ROS/Bim and TFRC/Fe2+ pathways
    1
    1. scibot 14 Jan 2023
      RRID:AB_2281980

      DOI: 10.1111/bph.15986

      Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)

      Curator: @scibot

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15986
  5. Sep 2022
  6. www.sciencedirect.com www.sciencedirect.com
    BET inhibition induces vulnerability to MCL1 targeting through upregulation of fatty acid synthesis pathway in breast cancer
    1
    1. scibot 15 Sep 2022
      RRID:AB_2281980

      DOI: 10.1016/j.celrep.2022.111304

      Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S2211124722011287
  7. Mar 2022
  8. elifesciences.org elifesciences.org
    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness
    1
    1. scibot 11 Mar 2022
      RRID:AB_2281980

      DOI: 10.7554/eLife.73150

      Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)

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    elifesciences.org/articles/73150
  9. Feb 2022
  10. www.sciencedirect.com www.sciencedirect.com
    A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells
    1
    1. scibot 23 Feb 2022
      RRID:AB_2281980

      DOI: 10.1016/j.molcel.2022.01.022

      Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)

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    sciencedirect.com/science/article/pii/S1097276522000879
  11. www.sciencedirect.com www.sciencedirect.com
    BCL-XL inhibition induces an FGFR4-mediated rescue response in colorectal cancer
    1
    1. scibot 16 Feb 2022
      AB_2281980

      DOI: 10.1016/j.celrep.2022.110374

      Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)

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    sciencedirect.com/science/article/pii/S221112472200095X
  12. Jul 2021
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined inhibition of the PI3K/mTOR/MEK pathway induces Bim/Mcl-1-regulated apoptosis in pancreatic cancer cells
    1
    1. scibot 29 Jul 2021
      AB_2281980

      DOI: 10.1080/15384047.2018.1504718

      Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)

      Curator: @bandrow

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      RRID:AB_2281980 RRIDCUR:Unrecognized
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    ncbi.nlm.nih.gov/pmc/articles/PMC6343713/
  14. www.sciencedirect.com www.sciencedirect.com
    Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer
    1
    1. scibot 22 Jul 2021
      RRID:AB_2281980

      DOI: 10.1016/j.celrep.2021.109394

      Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)

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    sciencedirect.com/science/article/pii/S2211124721007920
  15. May 2021
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ethanol Enhances Hyperthermia-Induced Cell Death in Human Leukemia Cells
    1
    1. scibot 19 May 2021
      RRID:AB_2281980

      DOI: 10.3390/ijms22094948

      Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)

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    ncbi.nlm.nih.gov/pmc/articles/PMC8125413/
  17. Feb 2021
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells
    1
    1. scibot 25 Feb 2021
      RRID:AB_2281980

      DOI: 10.1038/s41419-020-2589-7

      Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)

      Curator: @scibot

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    ncbi.nlm.nih.gov/pmc/articles/PMC7235254/
  19. Oct 2020
  20. www.sciencedirect.com www.sciencedirect.com
    The mTORC1/S6K/PDCD4/eIF4A Axis Determines Outcome of Mitotic Arrest
    1
    1. scibot 07 Oct 2020
      RRID:AB_2281980

      DOI: 10.1016/j.celrep.2020.108230

      Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)

      Curator: @Naa003

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      RRIDCUR:Validated RRID:AB_2281980
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    sciencedirect.com/science/article/pii/S2211124720312195
  21. Sep 2020
  22. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Synthesis, biological evaluation and toxicity of novel tetrandrine analogues
    1
    1. scibot 09 Sep 2020
      Mcl-1

      DOI: 10.1016/j.ejmech.2020.112810

      Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)

      Curator: @Naa003

      SciCrunch record: RRID:AB_2281980

      Curator comments: Mcl-1 Antibody Cell Signaling Technology Cat# 4572

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      RRID:AB_2281980 RRIDCUR:Missing
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    pubmed.ncbi.nlm.nih.gov/32942071/
  23. Jan 2020
  24. www.sciencedirect.com www.sciencedirect.com
    The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death
    1
    1. scibot 13 Jan 2020
      RRID:AB_2281980

      DOI: 10.1016/j.cell.2019.05.035

      Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)

      Curator: @ethanbadger

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      RRID:AB_2281980 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S009286741930563X
  25. www.nature.com www.nature.com
    ATG5 cancer mutations and alternative mRNA splicing reveal a conjugation switch that regulates ATG12–ATG5-ATG16L1 complex assembly and autophagy
    1
    1. scibot 13 Jan 2020
      RRID:AB_2281980

      DOI: 10.1038/s41421-019-0110-1

      Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)

      Curator: @Naa003

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      RRID:AB_2281980 RRIDCUR:Validated
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    nature.com/articles/s41421-019-0110-1
  26. www.sciencedirect.com www.sciencedirect.com
    Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity
    1
    1. scibot 13 Jan 2020
      RRID:AB_2281980

      DOI: 10.1016/j.celrep.2019.07.070

      Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)

      Curator: @ethanbadger

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      RRID:AB_2281980 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S221112471930974X
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells
    1
    1. scibot 13 Jan 2020
      RRID:AB_2281980

      DOI: 10.1038/s41408-018-0165-5

      Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)

      Curator: @evieth

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      RRID:AB_2281980 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6333829/
  28. Nov 2018
  29. www.tandfonline.com www.tandfonline.com
    Combined inhibition of the PI3K/mTOR/MEK pathway induces Bim/Mcl-2-regulated apoptosis in pancreatic cancer cells
    1
    1. scibot 05 Nov 2018
      AB_2281980

      Curator: @bandrow

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      (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)

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    tandfonline.com/doi/full/10.1080/15384047.2018.1504718