53 Matching Annotations
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    Hormetic fasting extends Caenorhabditis elegans lifespan via H3K27 acetylation of lipid catabolism and antioxidant genes
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    sciencedirect.com/science/article/pii/S2211124726005966
  3. May 2026
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    A human corticospinal organoid-slice connectoid model informs enhancer strategies for post-injury axon regrowth
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    sciencedirect.com/science/article/pii/S2211124726004778
  5. Apr 2026
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    Adenosine A2A Receptors Control the Mis-Localization of Aquaporin-4 in Rats Subject to Repeated Restraint Stress
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70450
  7. Mar 2026
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    ER-tethering directs TREX1 penetration of a BAF-dependent barrier at micronuclei
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    sciencedirect.com/science/article/pii/S1097276526001267
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    2026.02.25.707907.full-html.html
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  10. Jan 2026
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    Multimodal profiling of pancreatic cancer reveals a TIMP-1-dominated secretory profile determining pro-tumor immunoinstruction in human cancers
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    sciencedirect.com/science/article/pii/S2666379125006196
  12. Dec 2025
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    Combination of the MTA-Cooperative PRMT5 Inhibitor BMS-986504 and KRAS Inhibitors is an Effective Treatment Strategy for MTAP-Deleted KRAS-Mutant Pancreatic Cancer
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  14. Oct 2025
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    Defining the MYC-regulated transcriptome and kinome that support KRAS- and ERK-dependent growth of pancreatic cancer
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    science.org/doi/10.1126/scisignal.adu7145
  16. Sep 2025
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    The nuclear pore complex connects energy sensing to transcriptional plasticity in longevity
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  18. Jul 2025
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    FMRP drives mRNP targets into translationally silenced complexes
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    Chromosomal tethering and mitotic transcription promote ecDNA nuclear inheritance
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  21. Mar 2025
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    The nuclear pore complex connects energy sensing to transcriptional plasticity in longevity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11870510/
  24. Feb 2025
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    Taming interleukin-12: Engineering of bispecific antibody-based IL-12 mimetics with biased agonism capacities
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    onlinelibrary.wiley.com/doi/10.1002/pro.70072
  26. Dec 2024
  27. elifesciences.org elifesciences.org
    Full-length direct RNA sequencing uncovers stress granule-dependent RNA decay upon cellular stress
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    elifesciences.org/articles/96284
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    African ancestry neurodegeneration risk variant disrupts an intronic branchpoint in GBA1
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    link.springer.com/article/10.1038/s41594-024-01423-2
  29. Oct 2024
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NAPRT silencing in FH-deficient renal cell carcinoma confers therapeutic vulnerabilities via NAD+ depletion
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    ncbi.nlm.nih.gov/pmc/articles/PMC11445649/
  31. May 2024
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    Activation of M4 muscarinic receptors in the striatum reduces tic-like behaviours in two distinct murine models of Tourette syndrome
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16392
  33. Feb 2024
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    The clustered gamma protocadherin PcdhγC4 isoform regulates cortical interneuron programmed cell death in the mouse cortex
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  35. Nov 2023
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    Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies
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    sciencedirect.com/science/article/pii/S1535610823003665
  37. Oct 2023
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modification of astrocytic Cx43 hemichannel activity in animal models of AD: modulation by adenosine A2A receptors
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    pmc.ncbi.nlm.nih.gov/articles/PMC10613596/
  39. Aug 2023
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRAF7 is an essential regulator of blood vessel integrity during mouse embryonic and neonatal development
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    ncbi.nlm.nih.gov/pmc/articles/PMC10424150/
  41. May 2023
  42. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Astrocytic A2A receptors silencing negatively impacts hippocampal synaptic plasticity and memory of adult mice
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    onlinelibrary.wiley.com/doi/10.1002/glia.24384
  43. Mar 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of karyopherin β1-mediated nuclear import disrupts oncogenic lineage- defining transcription factor activity in small cell lung cancer
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  45. Feb 2023
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    Enhanced Expression of Plasminogen Activators and Inhibitor in the Healing of Tympanic Membrane Perforation in Rats
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    link.springer.com/article/10.1007/s10162-023-00891-5
  47. Dec 2022
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    Dephosphorylation of the pre-initiation complex is critical for origin firing
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    sciencedirect.com/science/article/pii/S1097276522011364
  49. Nov 2022
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    Mechanisms governing target search and binding dynamics of hypoxia-inducible factors
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    Integrative omics indicate FMRP sequesters mRNA from translation and deadenylation in human neuronal cells
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  52. Oct 2022
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    Targeting RTN4/NoGo-Receptor reduces levels of ALS protein ataxin-2
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    sciencedirect.com/science/article/pii/S2211124722013559
  54. Sep 2022
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    CCT196969 effectively inhibits growth and survival of melanoma brain metastasis cells
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  56. Aug 2022
  57. link.springer.com link.springer.com
    Aβ1-42 peptides blunt the adenosine A2A receptor-mediated control of the interplay between P2X7 and P2Y1 receptors mediated calcium responses in astrocytes
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    link.springer.com/article/10.1007/s00018-022-04492-y
  58. Jul 2022
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Corticosterone antagonist or TrkB agonist attenuates schizophrenia-like behavior in a mouse model combining Bdnf-e6 deficiency and developmental stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC9250029/
  60. Oct 2021
  61. www.nature.com www.nature.com
    SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion
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    nature.com/articles/s41586-021-03944-y
  62. Sep 2021
  63. link.springer.com link.springer.com
    Association Between Adenosine A2A Receptors and Connexin 43 Regulates Hemichannels Activity and ATP Release in Astrocytes Exposed to Amyloid-β Peptides
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    link.springer.com/article/10.1007/s12035-021-02538-z
  64. Jul 2021
  65. molecularbrain.biomedcentral.com molecularbrain.biomedcentral.com
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    molecularbrain.biomedcentral.com/articles/10.1186/s13041-018-0408-1
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    l-α-aminoadipate causes astrocyte pathology with negative impact on mouse hippocampal synaptic plasticity and memory
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202100336R
  68. Apr 2021
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    Argonaute-CLIP delineates versatile, functional RNAi networks in Aedes aegypti, a major vector of human viruses
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    sciencedirect.com/science/article/pii/S1931312821001323
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    Serotypic evolution of measles virus is constrained by multiple co-dominant B cell epitopes on its surface glycoproteins
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  71. Feb 2021
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    Targeting EphA2 suppresses hepatocellular carcinoma initiation and progression by dual inhibition of JAK1/STAT3 and AKT signaling
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    sciencedirect.com/science/article/pii/S2211124721000784
  73. www.cell.com www.cell.com
    TMEM41B IS A PAN-FLAVIVIRUS HOST FACTOR
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    cell.com/cell/abstract/S0092-8674(20)31627-5
  74. Jan 2021
  75. link.springer.com link.springer.com
    Motor Deficits Coupled to Cerebellar and Striatal Alterations in Ube3a m−/p+ Mice Modelling Angelman Syndrome Are Attenuated by Adenosine A 2A Receptor Blockade
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  76. Oct 2020
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TMEM41B is a pan-flavivirus host factor
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    ncbi.nlm.nih.gov/pmc/articles/PMC7553181/
  78. Sep 2020
  79. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Melatonin alters neuronal architecture and increases cysteine‐rich protein 1 signaling in the male mouse hippocampus
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    onlinelibrary.wiley.com/doi/10.1002/jnr.24708
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    Toll-like Receptor 5 Activation by the CagY Repeat Domains of Helicobacter pylori
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    sciencedirect.com/science/article/pii/S2211124720311487
  81. Jan 2020
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    Meiotic Kinetochores Fragment into Multiple Lobes upon Cohesin Loss in Aging Eggs
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    sciencedirect.com/science/article/pii/S0960982219311662
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    Plasma kallikrein‐kinin system contributes to peripheral inflammation in temporal lobe epilepsy
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14793
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  85. Nov 2018
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    Retrograde Degenerative Signaling Mediated by the p75 Neurotrophin Receptor Requires p150Glued Deacetylation by Axonal HDAC1
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    An RNAi screen of Rho signalling networks identifies RhoH as a regulator of Rac1 in prostate cancer cell migration
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    ncbi.nlm.nih.gov/pmc/articles/PMC5840776/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Method for the Acute and Rapid Degradation of Endogenous Proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC5733393/