42 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alzheimer’s disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling
    1
    1. scibot 23 Jul 2024
      RRID:AB_2289606

      DOI: 10.7554/eLife.90690

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    ncbi.nlm.nih.gov/pmc/articles/PMC11259434/
  3. May 2024
  4. www.mdpi.com www.mdpi.com
    Transcranial Magneto-Acoustic Stimulation Protects Synaptic Rehabilitation from Amyloid-Beta Plaques via Regulation of Microglial Functions
    1
    1. scibot 03 May 2024
      RRID:AB_2289606

      DOI: 10.3390/ijms25094651

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    mdpi.com/1422-0067/25/9/4651
  5. Oct 2023
  6. www.sciencedirect.com www.sciencedirect.com
    Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis
    1
    1. scibot 28 Oct 2023
      RRID:AB_2289606

      DOI: 10.1016/j.celrep.2023.113240

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    sciencedirect.com/science/article/pii/S2211124723012524
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Visualizing Wallerian degeneration in the corticospinal tract after sensorimotor cortex ischemia in mice
    1
    1. scibot 20 Oct 2023
      RRID:AB_2289606

      DOI: 10.4103/1673-5374.380903

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    ncbi.nlm.nih.gov/pmc/articles/PMC10581571/
  8. Sep 2023
  9. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Plk2 promotes synaptic destabilization through disruption of N-cadherin adhesion complexes during homeostatic adaptation to hyperexcitation
    1
    1. scibot 06 Sep 2023
      RRID:AB_2289606

      DOI: 10.1111/jnc.15948

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15948
  10. Aug 2023
  11. www.sciencedirect.com www.sciencedirect.com
    Neuronal γ-secretase regulates lipid metabolism, linking cholesterol to synaptic dysfunction in Alzheimer’s disease
    1
    1. scibot 05 Aug 2023
      RRID:AB_2289606

      DOI: 10.1016/j.neuron.2023.07.005

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    sciencedirect.com/science/article/pii/S0896627323005135
  12. Jul 2023
  13. www.sciencedirect.com www.sciencedirect.com
    Evidence for a clathrin-independent endocytic pathway for APP internalization in the neuronal somatodendritic compartment
    1
    1. scibot 13 Jul 2023
      RRID:AB_2289606

      DOI: 10.1016/j.celrep.2023.112774

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    sciencedirect.com/science/article/pii/S2211124723007854
  14. www.sciencedirect.com www.sciencedirect.com
    Hepatic soluble epoxide hydrolase activity regulates cerebral Aβ metabolism and the pathogenesis of Alzheimer’s disease in mice
    1
    1. scibot 06 Jul 2023
      RRID:AB_2289606

      DOI: 10.1016/j.neuron.2023.06.002

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    sciencedirect.com/science/article/pii/S0896627323004373
  15. Jun 2023
  16. www.sciencedirect.com www.sciencedirect.com
    ArhGAP11A mediates amyloid-β generation and neuropathology in an Alzheimer’s disease-like mouse model
    1
    1. scibot 16 Jun 2023
      RRID:AB_2289606

      DOI: 10.1016/j.celrep.2023.112624

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    sciencedirect.com/science/article/pii/S2211124723006356
  17. Apr 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Differential and substrate-specific inhibition of γ-secretase by the C-terminal region of ApoE2, ApoE3, and ApoE4
    1
    1. scibot 12 Apr 2023
      RRID:AB_2289606

      DOI: 10.1016/j.neuron.2023.03.024

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    sciencedirect.com/science/article/abs/pii/S0896627323002209
  19. Mar 2023
  20. journals.lww.com journals.lww.com
    Inhibiting 5-hydroxytryptamine receptor 3 alleviates... : Neural Regeneration Research
    1
    1. scibot 11 Mar 2023
      RRID:AB_2289606

      DOI: 10.4103/1673-5374.366492

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    journals.lww.com/nrronline/Fulltext/2023/09000/Inhibiting_5_hydroxytryptamine_receptor_3.30.aspx
  21. Oct 2022
  22. www.sciencedirect.com www.sciencedirect.com
    SYK coordinates neuroprotective microglial responses in neurodegenerative disease
    1
    1. scibot 20 Oct 2022
      RRID:AB_2289606

      DOI: 10.1016/j.cell.2022.09.030

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    sciencedirect.com/science/article/pii/S0092867422012491
  23. Sep 2022
  24. www.sciencedirect.com www.sciencedirect.com
    Molecular convergence between Down syndrome and fragile X syndrome identified using human pluripotent stem cell models
    1
    1. scibot 08 Sep 2022
      RRID:AB_2289606

      DOI: 10.1016/j.celrep.2022.111312

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    sciencedirect.com/science/article/pii/S2211124722011366
  25. Aug 2022
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of A Disintegrin and Metalloproteinase with Thrombospondin motifs 1 by a rare variant or cognitive activities reduces hippocampal amyloid-β and consequent Alzheimer’s disease risk
    1
    1. scibot 26 Aug 2022
      RRID:AB_2289606

      DOI: 10.3389/fnagi.2022.896522

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    ncbi.nlm.nih.gov/pmc/articles/PMC9395645/
  27. Jul 2022
  28. www.sciencedirect.com www.sciencedirect.com
    Inhibition of SIRT2 promotes APP acetylation and ameliorates cognitive impairment in APP/PS1 transgenic mice
    1
    1. scibot 13 Jul 2022
      AB_2289606

      DOI: 10.1016/j.celrep.2022.111062

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    sciencedirect.com/science/article/pii/S2211124722008609
  29. Jun 2022
  30. journals.lww.com journals.lww.com
    Icariin ameliorates memory deficits through regulating... : Neural Regeneration Research
    1
    1. scibot 24 Jun 2022
      RRID:AB_2289606

      DOI: 10.4103/1673-5374.344840

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    journals.lww.com/nrronline/Fulltext/2023/01000/Icariin_ameliorates_memory_deficits_through.39.aspx
  31. Apr 2022
  32. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 28 Apr 2022
      RRID:AB_2289606

      DOI: 10.1111/bph.15836

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15836
  33. Jan 2022
  34. www.sciencedirect.com www.sciencedirect.com
    The neuronal retromer can regulate both neuronal and microglial phenotypes of Alzheimer's disease
    1
    1. scibot 19 Jan 2022
      RRID:AB_2289606

      DOI: 10.1016/j.celrep.2021.110262

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    sciencedirect.com/science/article/pii/S2211124721017745
  35. Nov 2021
  36. www.sciencedirect.com www.sciencedirect.com
    Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells
    1
    1. scibot 19 Nov 2021
      RRID:AB_2289606

      DOI: 10.1016/j.neuron.2021.10.036

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    sciencedirect.com/science/article/pii/S0896627321008667
  37. Aug 2021
  38. www.nature.com www.nature.com
    Untitled document
    1
    1. scibot 03 Aug 2021
      RRID:AB_2289606

      DOI: 10.1038/s41598-019-39494-7

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    nature.com/articles/s41598-019-39494-7
  39. www.sciencedirect.com www.sciencedirect.com
    Increased P2×2 receptors induced by amyloid-β peptide participates in the neurotoxicity in alzheimer’s disease
    1
    1. scibot 03 Aug 2021
      RRID:AB_2289606

      DOI: 10.1016/j.biopha.2021.111968

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    sciencedirect.com/science/article/pii/S0753332221007502
  40. Jul 2021
  41. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Who's in, who's out? Re-evaluation of lipid raft residents
    1
    1. scibot 02 Jul 2021
      RRID:AB_2289606

      DOI: 10.1111/jnc.15446

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15446
  42. Jun 2021
  43. www.liebertpub.com www.liebertpub.com
    Antisense Oligonucleotide-Induced Amyloid Precursor Protein Splicing Modulation as a Therapeutic Approach for Dutch-Type Cerebral Amyloid Angiopathy
    1
    1. scibot 05 Jun 2021
      RRID:AB_2289606

      DOI: 10.1089/nat.2021.0005

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    liebertpub.com/doi/abs/10.1089/nat.2021.0005
  44. Mar 2021
  45. www.tandfonline.com www.tandfonline.com
    Ketogenic diet protects myelin and axons in diffuse axonal injury
    2
    1. scibot 15 Mar 2021
      RRID:AB_2289606

      DOI: 10.1080/1028415X.2021.1875300

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    2. scibot 10 Mar 2021
      RRID:AB_2289606

      DOI: 10.1080/1028415X.2021.1875300

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    tandfonline.com/doi/full/10.1080/1028415X.2021.1875300
  46. Feb 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial fission is a critical modulator of mutant APP-induced neural toxicity
    1
    1. scibot 26 Feb 2021
      RRID:AB_2289606

      DOI: 10.1016/j.jbc.2021.100469

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    sciencedirect.com/science/article/pii/S0021925821002428
  48. portlandpress.com portlandpress.com
    The cellular expression and proteolytic processing of the amyloid precursor protein is independent of TDP-43
    1
    1. scibot 25 Feb 2021
      RRID:AB_2289606

      DOI: 10.1042/BSR20200435

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    portlandpress.com/bioscirep/article/40/4/BSR20200435/222674/The-cellular-expression-and-proteolytic-processing
  49. Jan 2021
  50. www.sciencedirect.com www.sciencedirect.com
    Small Molecule SARM1 Inhibitors Recapitulate the SARM1−/− Phenotype and Allow Recovery of a Metastable Pool of Axons Fated to Degenerate
    1
    1. scibot 07 Jan 2021
      RRID:AB_2289606

      DOI: 10.1016/j.celrep.2020.108588

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    sciencedirect.com/science/article/pii/S2211124720315771
  51. Dec 2020
  52. www.cell.com www.cell.com
    APP Family Regulates Neuronal Excitability and Synaptic Plasticity but Not Neuronal Survival
    1
    1. scibot 19 Dec 2020
      RRID:AB_2289606

      DOI: 10.1016/j.neuron.2020.08.011

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    cell.com/neuron/abstract/S0896-6273(20)30642-5
  53. www.sciencedirect.com www.sciencedirect.com
    Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer’s Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals
    1
    1. scibot 16 Dec 2020
      RRID:AB_2289606

      DOI: 10.1016/j.cels.2020.11.007

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    sciencedirect.com/science/article/pii/S2405471220304580
  54. link.springer.com link.springer.com
    Cell-autonomous role of Presenilin in age-dependent survival of cortical interneurons
    1
    1. scibot 11 Dec 2020
      RRID:AB_2289606

      DOI: 10.1186/s13024-020-00419-y

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    link.springer.com/article/10.1186/s13024-020-00419-y
  55. Sep 2020
  56. www.sciencedirect.com www.sciencedirect.com
    Depletion of the AD Risk Gene SORL1 Selectively Impairs Neuronal Endosomal Traffic Independent of Amyloidogenic APP Processing
    1
    1. scibot 26 Sep 2020
      RRID:AB_2289606

      DOI: 10.1016/j.celrep.2020.107719

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    sciencedirect.com/science/article/pii/S2211124720306963
  57. www.sciencedirect.com www.sciencedirect.com
    Detection of Deleterious On-Target Effects after HDR-Mediated CRISPR Editing
    1
    1. scibot 25 Sep 2020
      RRID:AB_2289606

      DOI: 10.1016/j.celrep.2020.107689

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    sciencedirect.com/science/article/pii/S2211124720306422
  58. www.sciencedirect.com www.sciencedirect.com
    Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration
    1
    1. scibot 17 Sep 2020
      RRID:AB_2289606

      DOI: 10.1016/j.celrep.2020.107796

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    sciencedirect.com/science/article/pii/S2211124720307774
  59. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Necrostatin‐1 prevents the proapoptotic protein Bcl‐2/adenovirus E1B 19‐kDa interacting protein 3 from integration into mitochondria
    1
    1. scibot 15 Sep 2020
      RRID:AB_2289606

      DOI: 10.1111/jnc.14993

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14993
  60. link.springer.com link.springer.com
    Increased levels of Stress-inducible phosphoprotein-1 accelerates amyloid-β deposition in a mouse model of Alzheimer’s disease
    1
    1. scibot 12 Sep 2020
      RRID:AB_2289606

      DOI: 10.1186/s40478-020-01013-5

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    link.springer.com/article/10.1186/s40478-020-01013-5
  61. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 03 Sep 2020
      APP

      DOI: 10.1111/bph.15131

      Resource: (Abcam Cat# ab32136, RRID:AB_2289606)

      Curator: @Naa003

      SciCrunch record: RRID:AB_2289606

      Curator comments: Amyloid beta precursor protein antibody [Y188] Abcam Cat# ab32136

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      RRID:AB_2289606 RRIDCUR:Missing
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15131
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sodium butyrate inhibits high cholesterol-induced neuronal amyloidogenesis by modulating NRF2 stabilization-mediated ROS levels: involvement of NOX2 and SOD1
    1
    1. scibot 03 Sep 2020
      APP

      DOI: 10.1038/s41419-020-2663-1

      Resource: (Abcam Cat# ab32136, RRID:AB_2289606)

      Curator: @Naa003

      SciCrunch record: RRID:AB_2289606

      Curator comments: Amyloid beta precursor protein antibody [Y188] Abcam Cat# ab32136

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      RRID:AB_2289606 RRIDCUR:Missing
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    ncbi.nlm.nih.gov/pmc/articles/PMC7303181/
  63. Aug 2020
  64. elifesciences.org elifesciences.org
    Opposite changes in APP processing and human Aβ levels in rats carrying either a protective or a pathogenic APP mutation
    1
    1. scibot 14 Aug 2020
      RRID:AB_2289606

      DOI: 10.7554/eLife.52612

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      Curator: @evieth

      SciCrunch record: RRID:AB_2289606

      Curator comments: Abcam Cat# ab32136, Amyloid beta precursor protein antibody [Y188]

      What is this?
      RRID:AB_2289606
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    URL

    elifesciences.org/articles/52612
  65. Jan 2020
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic cerebral hypoperfusion shifts the equilibrium of amyloid β oligomers to aggregation-prone species with higher molecular weight
    1
    1. scibot 13 Jan 2020
      RRID:AB_2289606

      DOI: 10.1038/s41598-019-39494-7

      Resource: (Abcam Cat# ab32136, RRID:AB_2289606)

      Curator: @evieth

      SciCrunch record: RRID:AB_2289606

      What is this?

      RRID:AB_2289606 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6391466/
  67. www.jneurosci.org www.jneurosci.org
    Untitled document
    1
    1. scibot 13 Jan 2020
      RRID:AB_2289606

      DOI: 10.1523/JNEUROSCI.1280-17.2018

      Resource: (Abcam Cat# ab32136, RRID:AB_2289606)

      Curator: @Naa003

      SciCrunch record: RRID:AB_2289606

      What is this?

      RRID:AB_2289606 RRIDCUR:Validated
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    jneurosci.org/content/38/18/4288
  68. Nov 2018
  69. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The conformational epitope for a new Aβ42 protofibril‐selective antibody partially overlaps with the peptide N‐terminal region
    1
    1. scibot 05 Nov 2018
      RRID:AB_2289606

      Resource used:

      (Abcam Cat# ab32136, RRID:AB_2289606)

      SciCrunch record: RRID:AB_2289606

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2289606
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14211/full