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L-asparaginase treatment induces a tumor metabolic plasticity and reveals a vulnerability to PARP1/2 inhibitor Olaparib, in B-cell lymphomas

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1. scibot 30 Oct 2025
  
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  RRID:AB_2290281
  
  DOI: 10.1101/2025.10.24.683536
  
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biorxiv.org/content/10.1101/2025.10.24.683536v1
Aug 2025
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PARP inhibitors potentiate proton therapy end-of-range effects by accelerating replication forks and promoting transcription conflict

1
1. scibot 28 Aug 2025
  
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  DOI: 10.1016/j.ijrobp.2025.08.049
  
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sciencedirect.com/science/article/pii/S0360301625061978
Apr 2025
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Halting hepatocellular carcinoma: Identifying intercellular crosstalk in HBV-driven disease

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1. scibot 01 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115457
  
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sciencedirect.com/science/article/pii/S2211124725002281
Nov 2024
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A p38 MAPK-ROS axis fuels proliferation stress and DNA damage during CRISPR-Cas9 gene editing in hematopoietic stem and progenitor cells

1
1. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.xcrm.2024.101823
  
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sciencedirect.com/science/article/pii/S2666379124005949
Sep 2024
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Molecular basis of CX-5461-induced DNA damage response in primary vascular smooth muscle cells

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1. scibot 04 Sep 2024
  
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  DOI: 10.1016/j.heliyon.2024.e37227
  
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sciencedirect.com/science/article/pii/S2405844024132586
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Alphaherpesvirus manipulates retinoic acid metabolism for optimal replication

1
1. scibot 14 Jul 2024
  
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  RRID:AB_2290281
  
  DOI: 10.1016/j.isci.2024.110144
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11233922/
May 2024
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NRDE2 deficiency impairs homologous recombination repair and sensitizes hepatocellular carcinoma to PARP inhibitors

1
1. scibot 02 May 2024
  
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  RRID:AB_2290281
  
  DOI: 10.1016/j.xgen.2024.100550
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11099347/
Apr 2024
rupress.org rupress.org

DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response

2
1. scibot 25 Apr 2024
  
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  RRID:AB_2290281
  
  DOI: 10.1083/jcb.202303141
  
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2. scibot 25 Apr 2024
  
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  RRID:AB_2290281
  
  DOI: 10.1083/jcb.202303141
  
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rupress.org/jcb/article/223/5/e202303141/276604/DUX4-induced-HSATII-transcription-causes-KDM2A-B
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SETD2 loss and ATR inhibition synergize to promote cGAS signaling and immunotherapy response in renal cell carcinoma

1
1. scibot 03 Apr 2024
  
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  RRID:AB_2290281
  
  DOI: 10.1158/1078-0432.CCR-23-1003
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10592192/
Mar 2024
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Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape

1
1. scibot 29 Mar 2024
  
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  AB_2290281
  
  DOI: 10.1016/j.molcel.2024.02.032
  
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sciencedirect.com/science/article/pii/S1097276524001758
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma

1
1. scibot 08 Feb 2024
  
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  RRID:AB_2290281
  
  DOI: 10.1016/j.isci.2024.108925
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10844834/
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting DNA Repair and Survival Signaling in Diffuse Intrinsic Pontine Gliomas to Prevent Tumor Recurrence

1
1. scibot 05 Jan 2024
  
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  RRID:AB_2290281
  
  DOI: 10.1158/1535-7163.MCT-23-0026
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10762335/
Dec 2023
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Design, synthesis and mechanistic anticancer activity of new acetylated 5-aminosalicylate-thiazolinone hybrid derivatives

1
1. scibot 29 Dec 2023
  
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  RRID:AB_2290281
  
  DOI: 10.1016/j.isci.2023.108659
  
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sciencedirect.com/science/article/pii/S2589004223027360
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PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition

1
1. scibot 20 Dec 2023
  
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  RRID:AB_2290281
  
  DOI: 10.1016/j.xcrm.2023.101326
  
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sciencedirect.com/science/article/pii/S2666379123005438
Aug 2023
52.53.155.43 52.53.155.43

SSRN-id4513724-html.html

1
1. scibot 10 Aug 2023
  
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  RRID:AB_2290281
  
  DOI: 10.2139/ssrn.4513724
  
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52.53.155.43/5f78fb6f419d1fcb5e4cfbd3ef5a02650af33ba6/SSRN-id4513724-html.html
May 2023
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p53-independent tumor suppression by cell-cycle arrest via CREB/ATF transcription factor OASIS

1
1. scibot 13 May 2023
  
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  RRID:AB_2290281
  
  DOI: 10.1016/j.celrep.2023.112479
  
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sciencedirect.com/science/article/pii/S2211124723004904
Apr 2023
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Nuclear ATR lysine-tyrosylation protects against heart failure by activating DNA damage response

1
1. scibot 20 Apr 2023
  
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  RRID:AB_229028
  
  DOI: 10.1016/j.celrep.2023.112400
  
  Resource: (Cell Signaling Technology Cat# 2853, RRID:AB_2290281)
  
  Curator: @sofiakhan13
  
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  RRIDCUR:Unresolved RRID:AB_2290281
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sciencedirect.com/science/article/pii/S2211124723004114
Mar 2023
link.springer.com link.springer.com

VE-822 upregulates the deubiquitinase OTUD1 to stabilize FHL1 to inhibit the progression of lung adenocarcinoma

1
1. scibot 17 Mar 2023
  
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  RRID:AB_2290281
  
  DOI: 10.1007/s13402-023-00793-x
  
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link.springer.com/article/10.1007/s13402-023-00793-x
Aug 2022
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Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach

1
1. scibot 23 Aug 2022
  
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  RRID:AB_2290281
  
  DOI: 10.1016/j.crmeth.2022.100271
  
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sciencedirect.com/science/article/pii/S2667237522001485
Jun 2022
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Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration

1
1. scibot 17 Jun 2022
  
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  RRID:AB_2290281
  
  DOI: 10.1016/j.isci.2022.104519
  
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sciencedirect.com/science/article/pii/S2589004222007908
Apr 2022
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Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS

1
1. scibot 27 Apr 2022
  
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  RRID:AB_2290281
  
  DOI: 10.1016/j.molcel.2022.03.034
  
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sciencedirect.com/science/article/pii/S1097276522002908
Dec 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inhibition of ATM induces hypersensitivity to proton irradiation by upregulating toxic end joining

1
1. scibot 17 Dec 2021
  
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  RRID:AB_2290281
  
  DOI: 10.1158/0008-5472.CAN-20-2960
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8260463/
Jul 2021
physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com

Untitled document

1
1. scibot 31 Jul 2021
  
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  RRID:AB_2290281
  
  DOI: 10.1113/JP277367
  
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physoc.onlinelibrary.wiley.com/doi/full/10.1113/JP277367
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Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair

1
1. scibot 27 Jul 2021
  
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  RRID:AB_10120986
  
  DOI: 10.1016/j.ccell.2019.01.020
  
  Resource: (Cell Signaling Technology Cat# 2853, RRID:AB_2290281)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2290281
  
  Curator comments: Anti-ATR, Phospho (Ser428) Antibody, Unconjugated Cell Signaling Technology Cat# 2853 also 2853S, 2853P
  
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  RRID:AB_2290281 RRIDCUR:Unresolved RRIDCUR:Incorrect
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sciencedirect.com/science/article/pii/S1535610819300546
Jun 2021
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MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway

1
1. scibot 23 Jun 2021
  
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  AB_2290281
  
  DOI: 10.1016/j.ebiom.2021.103441
  
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sciencedirect.com/science/article/pii/S2352396421002346
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways

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1. scibot 16 Jun 2021
  
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  RRID:AB_2290281
  
  DOI: 10.3390/cancers13112840
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8201054/
Feb 2021
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FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

1
1. scibot 27 Feb 2021
  
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  RRID:AB_2290281
  
  DOI: 10.1016/j.cell.2020.11.042
  
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sciencedirect.com/science/article/pii/S0092867420316147
elifesciences.org elifesciences.org

The human origin recognition complex is essential for pre-RC assembly, mitosis, and maintenance of nuclear structure

1
1. scibot 24 Feb 2021
  
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  RRID:AB_2290281
  
  DOI: 10.7554/eLife.61797
  
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  Curator: @evieth
  
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  RRID:AB_2290281 RRIDCUR:Validated
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elifesciences.org/articles/61797
Dec 2020
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RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions

1
1. scibot 23 Dec 2020
  
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  RRID:AB_2290281
  
  DOI: 10.1016/j.celrep.2020.108546
  
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  RRID:AB_2290281 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720315357
Sep 2020
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Phospho-Ser784-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer

1
1. scibot 25 Sep 2020
  
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  RRID:AB_2290281
  
  DOI: 10.1016/j.celrep.2020.107745
  
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  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2290281
  
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  RRIDCUR:Validated RRID:AB_2290281
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sciencedirect.com/science/article/pii/S2211124720307257
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Replication Stress Induces Global Chromosome Breakage in the Fragile X Genome

1
1. scibot 25 Sep 2020
  
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  RRID:AB_2290281
  
  DOI: 10.1016/j.celrep.2020.108179
  
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  RRIDCUR:Validated RRID:AB_2290281
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pubmed.ncbi.nlm.nih.gov/32966779/
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L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis

1
1. scibot 17 Sep 2020
  
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  RRID:AB_2290281
  
  DOI: 10.1016/j.celrep.2020.107974
  
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  RRIDCUR:Validated RRID:AB_2290281
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sciencedirect.com/science/article/pii/S2211124720309554
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Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma

1
1. scibot 12 Sep 2020
  
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  RRID:AB_2290281
  
  DOI: 10.1016/j.ccell.2020.04.002
  
  Resource: (Cell Signaling Technology Cat# 2853, RRID:AB_2290281)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2290281
  
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  RRID:AB_2290281 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610820301641
Jan 2020
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Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2290281
  
  DOI: 10.1016/j.celrep.2019.07.070
  
  Resource: (Cell Signaling Technology Cat# 2853, RRID:AB_2290281)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2290281
  
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  RRID:AB_2290281 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S221112471930974X
Nov 2018
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Untitled document

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1. scibot 05 Nov 2018
  
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  RRID:AB_2290281
  
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  (Cell Signaling Technology Cat# 2853, RRID:AB_2290281)
  
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sciencedirect.com/science/article/pii/S2211124718314529
Nov 2017
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A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development

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1. scibot 08 Nov 2017
  
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  Curator: @Jmenke
  
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  RRID:AB_2290281 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610817303549
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Transcription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage Responses

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1. scibot 08 Nov 2017
  
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  RRID:AB_2290281
  
  Curator: @Jmenke
  
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  (Cell Signaling Technology Cat# 2853, RRID:AB_2290281)
  
  SciCrunch record: RRID:AB_2290281
  
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  RRID:AB_2290281 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867417308796