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  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alphaherpesvirus manipulates retinoic acid metabolism for optimal replication
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    1. scibot 14 Jul 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11233922/
  3. May 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NRDE2 deficiency impairs homologous recombination repair and sensitizes hepatocellular carcinoma to PARP inhibitors
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  5. Apr 2024
  6. rupress.org rupress.org
    DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response
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    SETD2 loss and ATR inhibition synergize to promote cGAS signaling and immunotherapy response in renal cell carcinoma
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  8. Mar 2024
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    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
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    sciencedirect.com/science/article/pii/S1097276524001758
  10. Feb 2024
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    RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma
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  12. Jan 2024
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    Targeting DNA Repair and Survival Signaling in Diffuse Intrinsic Pontine Gliomas to Prevent Tumor Recurrence
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  14. Dec 2023
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    Design, synthesis and mechanistic anticancer activity of new acetylated 5-aminosalicylate-thiazolinone hybrid derivatives
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    sciencedirect.com/science/article/pii/S2589004223027360
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    PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition
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  17. Aug 2023
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    SSRN-id4513724-html.html
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  19. May 2023
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    p53-independent tumor suppression by cell-cycle arrest via CREB/ATF transcription factor OASIS
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  21. Apr 2023
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    Nuclear ATR lysine-tyrosylation protects against heart failure by activating DNA damage response
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      DOI: 10.1016/j.celrep.2023.112400

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    sciencedirect.com/science/article/pii/S2211124723004114
  23. Mar 2023
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    VE-822 upregulates the deubiquitinase OTUD1 to stabilize FHL1 to inhibit the progression of lung adenocarcinoma
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      DOI: 10.1007/s13402-023-00793-x

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  25. Aug 2022
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    Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach
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      DOI: 10.1016/j.crmeth.2022.100271

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    sciencedirect.com/science/article/pii/S2667237522001485
  27. Jun 2022
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    Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration
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    sciencedirect.com/science/article/pii/S2589004222007908
  29. Apr 2022
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    Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS
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      DOI: 10.1016/j.molcel.2022.03.034

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    sciencedirect.com/science/article/pii/S1097276522002908
  31. Dec 2021
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of ATM induces hypersensitivity to proton irradiation by upregulating toxic end joining
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      DOI: 10.1158/0008-5472.CAN-20-2960

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  33. Jul 2021
  34. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
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    Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair
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      RRID:AB_10120986

      DOI: 10.1016/j.ccell.2019.01.020

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  36. Jun 2021
  37. www.sciencedirect.com www.sciencedirect.com
    MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway
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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways
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      DOI: 10.3390/cancers13112840

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    ncbi.nlm.nih.gov/pmc/articles/PMC8201054/
  39. Feb 2021
  40. www.sciencedirect.com www.sciencedirect.com
    FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells
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      DOI: 10.1016/j.cell.2020.11.042

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  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The human origin recognition complex is essential for pre-RC assembly, mitosis, and maintenance of nuclear structure
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      DOI: 10.7554/eLife.61797

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  42. Dec 2020
  43. www.sciencedirect.com www.sciencedirect.com
    RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions
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  44. Sep 2020
  45. www.sciencedirect.com www.sciencedirect.com
    Phospho-Ser784-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer
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    sciencedirect.com/science/article/pii/S2211124720307257
  46. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Replication Stress Induces Global Chromosome Breakage in the Fragile X Genome
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      DOI: 10.1016/j.celrep.2020.108179

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    L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis
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      DOI: 10.1016/j.celrep.2020.107974

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    sciencedirect.com/science/article/pii/S2211124720309554
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    Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma
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      DOI: 10.1016/j.ccell.2020.04.002

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    sciencedirect.com/science/article/pii/S1535610820301641
  49. Jan 2020
  50. www.sciencedirect.com www.sciencedirect.com
    Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity
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      DOI: 10.1016/j.celrep.2019.07.070

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    sciencedirect.com/science/article/pii/S221112471930974X
  51. Nov 2018
  52. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S2211124718314529
  53. Nov 2017
  54. www.sciencedirect.com www.sciencedirect.com
    A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development
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    sciencedirect.com/science/article/pii/S1535610817303549
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    Transcription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage Responses
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    sciencedirect.com/science/article/pii/S0092867417308796