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  1. Last 7 days
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    NRDE2 deficiency impairs homologous recombination repair and sensitizes hepatocellular carcinoma to PARP inhibitors
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    sciencedirect.com/science/article/pii/S2666979X2400106X
  3. Apr 2024
  4. rupress.org rupress.org
    DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response
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    rupress.org/jcb/article/223/5/e202303141/276604/DUX4-induced-HSATII-transcription-causes-KDM2A-B
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    SETD2 loss and ATR inhibition synergize to promote cGAS signaling and immunotherapy response in renal cell carcinoma
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  6. Mar 2024
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    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
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    sciencedirect.com/science/article/pii/S1097276524001758
  8. Feb 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844834/
  10. Jan 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting DNA Repair and Survival Signaling in Diffuse Intrinsic Pontine Gliomas to Prevent Tumor Recurrence
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  12. Dec 2023
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    Design, synthesis and mechanistic anticancer activity of new acetylated 5-aminosalicylate-thiazolinone hybrid derivatives
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    sciencedirect.com/science/article/pii/S2589004223027360
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    PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition
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    1. scibot 20 Dec 2023
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  15. Aug 2023
  16. 52.53.155.43 52.53.155.43
    SSRN-id4513724-html.html
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  17. May 2023
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    p53-independent tumor suppression by cell-cycle arrest via CREB/ATF transcription factor OASIS
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    1. scibot 13 May 2023
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    sciencedirect.com/science/article/pii/S2211124723004904
  19. Apr 2023
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    Nuclear ATR lysine-tyrosylation protects against heart failure by activating DNA damage response
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    1. scibot 20 Apr 2023
      RRID:AB_229028

      DOI: 10.1016/j.celrep.2023.112400

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    sciencedirect.com/science/article/pii/S2211124723004114
  21. Mar 2023
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    VE-822 upregulates the deubiquitinase OTUD1 to stabilize FHL1 to inhibit the progression of lung adenocarcinoma
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    1. scibot 17 Mar 2023
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      DOI: 10.1007/s13402-023-00793-x

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  23. Aug 2022
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    Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach
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      DOI: 10.1016/j.crmeth.2022.100271

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    sciencedirect.com/science/article/pii/S2667237522001485
  25. Jun 2022
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    Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration
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      DOI: 10.1016/j.isci.2022.104519

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    sciencedirect.com/science/article/pii/S2589004222007908
  27. Apr 2022
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    Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS
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      DOI: 10.1016/j.molcel.2022.03.034

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    sciencedirect.com/science/article/pii/S1097276522002908
  29. Dec 2021
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of ATM induces hypersensitivity to proton irradiation by upregulating toxic end joining
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      DOI: 10.1158/0008-5472.CAN-20-2960

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    ncbi.nlm.nih.gov/pmc/articles/PMC8260463/
  31. Jul 2021
  32. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
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    1. scibot 31 Jul 2021
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      DOI: 10.1113/JP277367

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    physoc.onlinelibrary.wiley.com/doi/full/10.1113/JP277367
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    Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair
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    1. scibot 27 Jul 2021
      RRID:AB_10120986

      DOI: 10.1016/j.ccell.2019.01.020

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    sciencedirect.com/science/article/pii/S1535610819300546
  34. Jun 2021
  35. www.sciencedirect.com www.sciencedirect.com
    MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway
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    sciencedirect.com/science/article/pii/S2352396421002346
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways
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    1. scibot 16 Jun 2021
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      DOI: 10.3390/cancers13112840

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    ncbi.nlm.nih.gov/pmc/articles/PMC8201054/
  37. Feb 2021
  38. www.sciencedirect.com www.sciencedirect.com
    FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells
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      DOI: 10.1016/j.cell.2020.11.042

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    sciencedirect.com/science/article/pii/S0092867420316147
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The human origin recognition complex is essential for pre-RC assembly, mitosis, and maintenance of nuclear structure
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      DOI: 10.7554/eLife.61797

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  40. Dec 2020
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    RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions
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      DOI: 10.1016/j.celrep.2020.108546

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    sciencedirect.com/science/article/pii/S2211124720315357
  42. Sep 2020
  43. www.sciencedirect.com www.sciencedirect.com
    Phospho-Ser784-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer
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      DOI: 10.1016/j.celrep.2020.107745

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    sciencedirect.com/science/article/pii/S2211124720307257
  44. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Replication Stress Induces Global Chromosome Breakage in the Fragile X Genome
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    1. scibot 25 Sep 2020
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      DOI: 10.1016/j.celrep.2020.108179

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    pubmed.ncbi.nlm.nih.gov/32966779/
  45. www.sciencedirect.com www.sciencedirect.com
    L ARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis
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      DOI: 10.1016/j.celrep.2020.107974

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    sciencedirect.com/science/article/pii/S2211124720309554
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    Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma
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    1. scibot 12 Sep 2020
      RRID:AB_2290281

      DOI: 10.1016/j.ccell.2020.04.002

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    sciencedirect.com/science/article/pii/S1535610820301641
  47. Jan 2020
  48. www.sciencedirect.com www.sciencedirect.com
    Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity
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      RRID:AB_2290281

      DOI: 10.1016/j.celrep.2019.07.070

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    sciencedirect.com/science/article/pii/S221112471930974X
  49. Nov 2018
  50. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S2211124718314529
  51. Nov 2017
  52. www.sciencedirect.com www.sciencedirect.com
    A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development
    1
    1. scibot 08 Nov 2017
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1535610817303549
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    Transcription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage Responses
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    1. scibot 08 Nov 2017
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    sciencedirect.com/science/article/pii/S0092867417308796