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AMBRA1 enhances Sonic Hedgehog signaling during cerebellar development and in medulloblastoma

1
1. scibot 16 Apr 2026
  
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  RRID:AB_2294746
  
  DOI: 10.1016/j.devcel.2026.03.008
  
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sciencedirect.com/science/article/pii/S1534580726001206
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Multiple modes of cholesterol translocation in the human Smoothened receptor

1
1. scibot 18 Mar 2026
  
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  RRID:AB_2294746
  
  DOI: 10.7554/eLife.108030
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12978703/
Jan 2025
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Non-cell-autonomous regulation of mTORC2 by Hedgehog signaling maintains lipid homeostasis

1
1. scibot 09 Jan 2025
  
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  RRID:AB_2294746
  
  DOI: 10.1016/j.celrep.2024.115191
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
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sciencedirect.com/science/article/pii/S2211124724015420
Dec 2024
www.biorxiv.org www.biorxiv.org

Energetics of cholesterol perception and translocation in the human Smoothened receptor

1
1. scibot 06 Dec 2024
  
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  RRID: AB 2294746
  
  DOI: 10.1101/2024.11.25.625241
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
  Curator: @AlecAsdourian
  
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biorxiv.org/content/10.1101/2024.11.25.625241v2
Mar 2024
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A sterol analog inhibits hedgehog pathway by blocking cholesterylation of smoothened

3
1. scibot 05 Mar 2024
  
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  RRID:AB_2294746
  
  DOI: 10.1016/j.chembiol.2024.02.002
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
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2. scibot 05 Mar 2024
  
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  RRID:AB_2294746
  
  DOI: 10.1016/j.chembiol.2024.02.002
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
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3. scibot 05 Mar 2024
  
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  RRID:AB_2294746
  
  DOI: 10.1016/j.chembiol.2024.02.002
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
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sciencedirect.com/science/article/pii/S245194562400076X
Oct 2023
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Towards modular engineering of cell signalling: Topographically-textured microparticles induce osteogenesis via activation of canonical hedgehog signalling

1
1. scibot 14 Oct 2023
  
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  RRID:AB_2294746
  
  DOI: 10.1016/j.bioadv.2023.213652
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
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sciencedirect.com/science/article/pii/S2772950823003758
Dec 2022
www.embopress.org www.embopress.org

GRAMD1/ASTER-mediated cholesterol transport promotes Smoothened cholesterylation at the endoplasmic reticulum

1
1. scibot 20 Dec 2022
  
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  RRID:AB_2294746
  
  DOI: 10.15252/embj.2022111513
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
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embopress.org/doi/10.15252/embj.2022111513
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Lhx2 is a progenitor-intrinsic modulator of Sonic Hedgehog signaling during early retinal neurogenesis

1
1. scibot 06 Dec 2022
  
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  RRID:AB_2294746
  
  DOI: 10.7554/eLife.78342
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9718532/
Nov 2022
aacrjournals.org aacrjournals.org

A druggable UHRF1/DNMT1/GLI complex regulates Sonic hedgehog dependent tumor growth

1
1. scibot 22 Nov 2022
  
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  RRID:AB_2294746
  
  DOI: 10.1158/1541-7786.MCR-22-0182
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
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aacrjournals.org/mcr/article/20/11/1598/709855/A-Druggable-UHRF1-DNMT1-GLI-Complex-Regulates
Oct 2022
52.53.155.43 52.53.155.43

mcr-22-0182-html.html

1
1. scibot 29 Oct 2022
  
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  RRID:AB_2294746
  
  DOI: 10.1158/1541-7786.mcr-22-0182
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
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52.53.155.43/736c3e45aba95f2b9e7e9af3df073f3bca899f3f/mcr-22-0182-html.html
Jun 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain

1
1. scibot 22 Jun 2022
  
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  RRID:AB_2294746
  
  DOI: 10.1126/sciadv.abm5563
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9166294/
www.science.org www.science.org

Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain

1
1. scibot 07 Jun 2022
  
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  RRID:AB_2294746
  
  DOI: 10.1126/sciadv.abm5563
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
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science.org/doi/full/10.1126/sciadv.abm5563
Dec 2021
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Yap-Myc signaling induces pancreatic stellate cell activation through regulating glutaminolysis

1
1. scibot 28 Dec 2021
  
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  2643
  
  DOI: 10.1016/j.yexcr.2021.113000
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
  Curator: @Naa003
  
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  RRID:AB_2294746 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S0014482721005565
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Ciliary and extraciliary Gpr161 pools repress hedgehog signaling in a tissue-specific manner

1
1. scibot 25 Aug 2021
  
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  RRID:AB_2294746
  
  DOI: 10.7554/eLife.67121
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8378848/
May 2021
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A Membrane-Tethered Ubiquitination Pathway Regulates Hedgehog Signaling and Heart Development

1
1. scibot 05 May 2021
  
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  RRID:AB_2294746
  
  DOI: 10.1016/j.devcel.2020.08.012
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1534580720306705
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Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling

1
1. scibot 05 May 2021
  
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  RRID:AB_2294746
  
  DOI: 10.1016/j.devcel.2020.06.034
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1534580720305426
Sep 2020
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H1N1 Influenza Virus Cross-Activates Gli1 to Disrupt the Intercellular Junctions of Alveolar Epithelial Cells

1
1. scibot 26 Sep 2020
  
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  RRID:AB_2294746
  
  DOI: 10.1016/j.celrep.2020.107801
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2294746
  
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  RRID:AB_2294746 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720307828
academic.oup.com academic.oup.com

Hedgehog signaling enables repair of ribosomal DNA double-strand breaks

1
1. scibot 13 Sep 2020
  
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  GLI1
  
  DOI: 10.1093/nar/gkaa733
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2294746
  
  Curator comments: GLI1 (L42B10) Mouse mAb antibody Cell Signaling Technology Cat# 2643
  
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  RRID:AB_2294746 RRIDCUR:Missing
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academic.oup.com/nar/advance-article/doi/10.1093/nar/gkaa733/5902436
www.sciencedirect.com www.sciencedirect.com

Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module

1
1. scibot 03 Sep 2020
  
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  RRID:AB_2294746
  
  DOI: 10.1016/j.celrep.2020.01.024
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2294746
  
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  RRID:AB_2294746 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720300334
Jan 2020
www.sciencedirect.com www.sciencedirect.com

MicroRNA inhibition upregulates hippocampal A-type potassium current and reduces seizure frequency in a mouse model of epilepsy

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2294746
  
  DOI: 10.1016/j.nbd.2019.104508
  
  Resource: (Cell Signaling Technology Cat# 2643, RRID:AB_2294746)
  
  Curator: @Naa003
  
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  RRID:AB_2294746 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0969996119301688
Nov 2018
www.sciencedirect.com www.sciencedirect.com

https://www.ncbi.nlm.nih.gov/pubmed/29290584

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2294746
  
  Curator: @evieth
  
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  (Cell Signaling Technology Cat# 2643S, RRID:AB_2294746)
  
  SciCrunch record: RRID:AB_2294746
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_2294746 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1534580717309887