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Programmable apoptosis circuits enable subtractive engineering of stem cell-derived organoids and embryoids

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1. scibot 24 Oct 2026
  
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  DOI: 10.1016/j.stem.2026.09.015
  
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sciencedirect.com/science/article/pii/S1934590926003796
Oct 2026
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Enhanced liver regeneration via targeted mRNA delivery for partial in vivo reprogramming

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1. scibot 03 Oct 2026
  
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  DOI: 10.1016/j.xcrm.2026.103084
  
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sciencedirect.com/science/article/pii/S266637912600501X
Sep 2026
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IGF2 acts downstream of Hippo signaling to regulate organ growth and restore liver regeneration in aging

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1. scibot 09 Sep 2026
  
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  DOI: 10.1016/j.stem.2026.08.006
  
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sciencedirect.com/science/article/pii/S1934590926003073
Jul 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

KLF4 Promotes a KRT13+ Hillock-Like State in Lung Squamous Cell Carcinoma

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1. scibot 17 Jul 2026
  
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  DOI: 10.1158/0008-5472.CAN-26-0531
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13371669/
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Setdb1 safeguards proper differentiation of adult intestinal stem cells by controlling chromatin accessibility and transcriptome variability

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1. scibot 11 Jul 2026
  
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  DOI: 10.1016/j.isci.2026.116731
  
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sciencedirect.com/science/article/pii/S2589004226021097
May 2026
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Epigenomic profiling of neuroendocrine lung cancers identifies a classical-neuroendocrine ASCL1/NKX2-1 subtype and a SOX11-associated differentiation axis linked to reduced immunogenicity

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1. scibot 19 May 2026
  
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  DOI: 10.1016/j.lungcan.2026.109464
  
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sciencedirect.com/science/article/pii/S0169500226005258
Apr 2026
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The robust, high-throughput, and temporally regulated roxCre and loxCre reporting systems for genetic modifications in vivo

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1. scibot 25 Apr 2026
  
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  DOI: 10.7554/eLife.97717
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13095210/
Mar 2026
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Opposing lineage specifiers induce a protumor hybrid identity state in lung adenocarcinoma

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1. scibot 03 Mar 2026
  
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  DOI: 10.1101/gad.352742.125
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12404196/
Oct 2025
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The validation of quality attributes in Primary Human Hepatocytes Standard

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1. scibot 21 Oct 2025
  
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  DOI: 10.1186/s13619-025-00258-6
  
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link.springer.com/article/10.1186/s13619-025-00258-6
Aug 2025
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Hepatocyte metabolic adaptations during pregnancy and lactation

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1. scibot 29 Aug 2025
  
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  DOI: 10.1016/j.cell.2025.08.007
  
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sciencedirect.com/science/article/pii/S0092867425009213
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Differential control of growth and identity by HNF4α isoforms in pancreatic ductal adenocarcinoma

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1. scibot 10 Aug 2025
  
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  DOI: 10.1158/1541-7786.MCR-25-0175
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12333154/
May 2025
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Integrating collecting systems in human kidney organoids through fusion of distal nephron to ureteric bud

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1. scibot 18 May 2025
  
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  DOI: 10.1016/j.stem.2025.04.008
  
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sciencedirect.com/science/article/pii/S1934590925001432
Feb 2025
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EHBP1 suppresses liver fibrosis in metabolic dysfunction-associated steatohepatitis

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1. scibot 27 Feb 2025
  
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  RRID:AB_2295208
  
  DOI: 10.1016/j.cmet.2025.01.020
  
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sciencedirect.com/science/article/pii/S1550413125000191
Jan 2025
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Spatiotemporal and genetic cell lineage tracing of endodermal organogenesis at single-cell resolution

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1. scibot 17 Jan 2025
  
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  DOI: 10.1016/j.cell.2024.12.012
  
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sciencedirect.com/science/article/pii/S0092867424014259
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PDF-html.html

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1. scibot 05 Jan 2025
  
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  DOI: 10.1242/dev.203033
  
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52.53.155.43/0a0e2be3fd070b626490de805f839f32bed421ca/PDF-html.html
Nov 2024
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FoxA1/2-dependent epigenomic reprogramming drives lineage switching in lung adenocarcinoma

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1. scibot 11 Nov 2024
  
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  DOI: 10.1016/j.devcel.2024.10.009
  
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sciencedirect.com/science/article/pii/S1534580724006282
May 2024
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Molecular subtypes of neuroendocrine carcinomas: A cross-tissue classification framework based on five transcriptional regulators

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1. scibot 24 May 2024
  
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  RRID:AB_2295208
  
  DOI: 10.1016/j.ccell.2024.05.002
  
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sciencedirect.com/science/article/pii/S1535610824001636
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Modeling alcohol-associated liver disease in humans using adipose stromal or stem cell-derived organoids

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1. scibot 16 May 2024
  
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  RRID:AB_2295208
  
  DOI: 10.1016/j.crmeth.2024.100778
  
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sciencedirect.com/science/article/pii/S266723752400122X
Apr 2024
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NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo

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1. scibot 05 Apr 2024
  
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  RRID:AB_2295208
  
  DOI: 10.1016/j.stem.2024.03.003
  
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sciencedirect.com/science/article/pii/S1934590924000845
Oct 2023
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Spatial-temporal proliferation of hepatocytes during pregnancy revealed by genetic lineage tracing

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1. scibot 14 Oct 2023
  
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  DOI: 10.1016/j.stem.2023.09.002
  
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sciencedirect.com/science/article/pii/S1934590923003235
Jul 2023
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Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation

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1. scibot 27 Jul 2023
  
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  DOI: 10.1016/j.devcel.2023.07.001
  
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sciencedirect.com/science/article/pii/S1534580723003313
Jun 2023
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Loss of Mettl3 enhances liver tumorigenesis by inducing hepatocyte dedifferentiation and hyperproliferation

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1. scibot 28 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112704
  
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sciencedirect.com/science/article/pii/S2211124723007155
www.nature.com www.nature.com

Genetic recording of in vivo cell proliferation by ProTracer

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1. scibot 04 Jun 2023
  
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  DOI: 10.1038/s41596-023-00833-8
  
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nature.com/articles/s41596-023-00833-8
Mar 2023
www.embopress.org www.embopress.org

Two Hippo signaling modules orchestrate liver size and tumorigenesis

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1. scibot 16 Mar 2023
  
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  DOI: 10.15252/embj.2022112126
  
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2. scibot 16 Mar 2023
  
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  DOI: 10.15252/embj.2022112126
  
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embopress.org/doi/10.15252/embj.2022112126
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Genotype-phenotype mapping of a patient-derived lung cancer organoid biobank identifies NKX2-1-defined Wnt dependency in lung adenocarcinoma

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1. scibot 11 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112212
  
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sciencedirect.com/science/article/pii/S2211124723002231
Dec 2022
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Embryogenic stem cell-derived intestinal crypt fission directs de novo crypt genesis

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1. scibot 18 Dec 2022
  
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  DOI: 10.1016/j.celrep.2022.111796
  
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sciencedirect.com/science/article/pii/S2211124722016849
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CRISPR/Cas9 mediated approach to generate YAP-depleted human embryonic stem cell line (MUSIe002-A-1)

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1. scibot 06 Dec 2022
  
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  DOI: 10.1016/j.scr.2022.102990
  
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sciencedirect.com/science/article/pii/S1873506122003397
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A scalable and tunable thermoreversible polymer for 3D human pluripotent stem cell biomanufacturing

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1. scibot 22 Sep 2022
  
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  DOI: 10.1016/j.isci.2022.104971
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9485071/
Aug 2022
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Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development

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1. scibot 23 Aug 2022
  
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  DOI: 10.1016/j.isci.2022.104905
  
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sciencedirect.com/science/article/pii/S2589004222011774
Jul 2022
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FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma

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1. scibot 15 Jul 2022
  
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  DOI: 10.1016/j.devcel.2022.06.017
  
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sciencedirect.com/science/article/pii/S1534580722004580
Apr 2022
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The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes

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1. scibot 22 Apr 2022
  
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  DOI: 10.1016/j.stem.2022.03.015
  
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sciencedirect.com/science/article/pii/S1934590922001503
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WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy

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1. scibot 20 Apr 2022
  
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  DOI: 10.1016/j.molcel.2022.03.027
  
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sciencedirect.com/science/article/pii/S1097276522002659
Jan 2022
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Derivation of the MUSIe002-A human embryonic stem cell line

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1. scibot 11 Jan 2022
  
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  DOI: 10.1016/j.scr.2022.102660
  
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sciencedirect.com/science/article/pii/S1873506122000095
Nov 2021
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Genome-wide screening in human kidney organoids identifies developmental and disease-related aspects of nephrogenesis

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1. scibot 30 Nov 2021
  
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  DOI: 10.1016/j.stem.2021.11.001
  
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sciencedirect.com/science/article/pii/S1934590921004495
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Modeling population size independent tissue epigenomes by ChIL‐seq with single thin sections

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1. scibot 15 Nov 2021
  
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  DOI: 10.15252/msb.202110323
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8564819/
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Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation

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Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors

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A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting

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The Dynamics of Transcriptional Activation by Hepatic Reprogramming Factors

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Bookmarking by Non-pioneer Transcription Factors during Liver Development Establishes Competence for Future Gene Activation

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Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids

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Bookmarking by Non-pioneer Transcription Factors during Liver Development Establishes Competence for Future Gene Activation

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BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells

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HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer

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AXIN2+ Pericentral Hepatocytes Have Limited Contributions to Liver Homeostasis and Regeneration

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FoxA1 and FoxA2 drive gastric differentiation and suppress squamous identity in NKX2-1-negative lung cancer

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iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications

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The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment

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Selective Inhibition of FOXO1 Activator/Repressor Balance Modulates Hepatic Glucose Handling

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Generation of human embryonic stem cell line with heterozygous RB1 deletion by CRIPSR/Cas9 nickase

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Intrinsic Immunity Shapes Viral Resistance of Stem Cells

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