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Opposing lineage specifiers induce a protumor hybrid identity state in lung adenocarcinoma

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1. scibot 03 Mar 2026
  
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  DOI: 10.1101/gad.352742.125
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12404196/
Oct 2025
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The validation of quality attributes in Primary Human Hepatocytes Standard

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  DOI: 10.1186/s13619-025-00258-6
  
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link.springer.com/article/10.1186/s13619-025-00258-6
Aug 2025
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Hepatocyte metabolic adaptations during pregnancy and lactation

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  DOI: 10.1016/j.cell.2025.08.007
  
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Differential control of growth and identity by HNF4α isoforms in pancreatic ductal adenocarcinoma

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pmc.ncbi.nlm.nih.gov/articles/PMC12333154/
May 2025
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Integrating collecting systems in human kidney organoids through fusion of distal nephron to ureteric bud

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sciencedirect.com/science/article/pii/S1934590925001432
Feb 2025
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EHBP1 suppresses liver fibrosis in metabolic dysfunction-associated steatohepatitis

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Jan 2025
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Spatiotemporal and genetic cell lineage tracing of endodermal organogenesis at single-cell resolution

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Nov 2024
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FoxA1/2-dependent epigenomic reprogramming drives lineage switching in lung adenocarcinoma

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1. scibot 11 Nov 2024
  
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May 2024
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Molecular subtypes of neuroendocrine carcinomas: A cross-tissue classification framework based on five transcriptional regulators

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sciencedirect.com/science/article/pii/S1535610824001636
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Modeling alcohol-associated liver disease in humans using adipose stromal or stem cell-derived organoids

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  DOI: 10.1016/j.crmeth.2024.100778
  
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Apr 2024
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NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo

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sciencedirect.com/science/article/pii/S1934590924000845
Oct 2023
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Spatial-temporal proliferation of hepatocytes during pregnancy revealed by genetic lineage tracing

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1. scibot 14 Oct 2023
  
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  DOI: 10.1016/j.stem.2023.09.002
  
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sciencedirect.com/science/article/pii/S1934590923003235
Jul 2023
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Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation

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1. scibot 27 Jul 2023
  
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  DOI: 10.1016/j.devcel.2023.07.001
  
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Jun 2023
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Loss of Mettl3 enhances liver tumorigenesis by inducing hepatocyte dedifferentiation and hyperproliferation

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1. scibot 28 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112704
  
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sciencedirect.com/science/article/pii/S2211124723007155
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Genetic recording of in vivo cell proliferation by ProTracer

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1. scibot 04 Jun 2023
  
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  DOI: 10.1038/s41596-023-00833-8
  
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nature.com/articles/s41596-023-00833-8
Mar 2023
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Two Hippo signaling modules orchestrate liver size and tumorigenesis

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  DOI: 10.15252/embj.2022112126
  
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  DOI: 10.15252/embj.2022112126
  
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embopress.org/doi/10.15252/embj.2022112126
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Genotype-phenotype mapping of a patient-derived lung cancer organoid biobank identifies NKX2-1-defined Wnt dependency in lung adenocarcinoma

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1. scibot 11 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112212
  
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sciencedirect.com/science/article/pii/S2211124723002231
Dec 2022
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Embryogenic stem cell-derived intestinal crypt fission directs de novo crypt genesis

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1. scibot 18 Dec 2022
  
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sciencedirect.com/science/article/pii/S2211124722016849
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CRISPR/Cas9 mediated approach to generate YAP-depleted human embryonic stem cell line (MUSIe002-A-1)

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1. scibot 06 Dec 2022
  
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sciencedirect.com/science/article/pii/S1873506122003397
Sep 2022
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A scalable and tunable thermoreversible polymer for 3D human pluripotent stem cell biomanufacturing

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  DOI: 10.1016/j.isci.2022.104971
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9485071/
Aug 2022
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Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development

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sciencedirect.com/science/article/pii/S2589004222011774
Jul 2022
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FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma

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1. scibot 15 Jul 2022
  
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sciencedirect.com/science/article/pii/S1534580722004580
Apr 2022
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The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes

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1. scibot 22 Apr 2022
  
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  DOI: 10.1016/j.stem.2022.03.015
  
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WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy

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1. scibot 20 Apr 2022
  
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  DOI: 10.1016/j.molcel.2022.03.027
  
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sciencedirect.com/science/article/pii/S1097276522002659
Jan 2022
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Derivation of the MUSIe002-A human embryonic stem cell line

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sciencedirect.com/science/article/pii/S1873506122000095
Nov 2021
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Genome-wide screening in human kidney organoids identifies developmental and disease-related aspects of nephrogenesis

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1. scibot 30 Nov 2021
  
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Modeling population size independent tissue epigenomes by ChIL‐seq with single thin sections

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1. scibot 15 Nov 2021
  
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  DOI: 10.15252/msb.202110323
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8564819/
Sep 2021
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Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation

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1. scibot 08 Sep 2021
  
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  DOI: 10.1016/j.celrep.2021.109659
  
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sciencedirect.com/science/article/pii/S2211124721011037
Jul 2021
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Untitled document

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  DOI: 10.1016/j.cell.2017.11.018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5786493/
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Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors

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  DOI: 10.1016/j.celrep.2021.109310
  
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sciencedirect.com/science/article/pii/S2211124721006860
May 2021
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A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting

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1. scibot 09 May 2021
  
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sciencedirect.com/science/article/pii/S1934590921000072
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The Dynamics of Transcriptional Activation by Hepatic Reprogramming Factors

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  DOI: 10.1016/j.molcel.2020.07.012
  
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sciencedirect.com/science/article/pii/S1097276520305025
Feb 2021
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Bookmarking by Non-pioneer Transcription Factors during Liver Development Establishes Competence for Future Gene Activation

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1. scibot 24 Feb 2021
  
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  DOI: 10.1016/j.celrep.2020.01.006
  
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cell.com/cell-reports/abstract/S2211-1247(20)30015-2
Dec 2020
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Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids

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1. scibot 13 Dec 2020
  
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  DOI: 10.1016/j.cels.2020.11.002
  
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sciencedirect.com/science/article/pii/S2405471220304208
Sep 2020
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Bookmarking by Non-pioneer Transcription Factors during Liver Development Establishes Competence for Future Gene Activation

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  DOI: 10.1016/j.celrep.2020.01.006
  
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cell.com/cell-reports/abstract/S2211-1247(20)30015-2
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BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells

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  DOI: 10.1038/s41419-020-2589-7
  
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HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer

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1. scibot 09 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107625
  
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AXIN2+ Pericentral Hepatocytes Have Limited Contributions to Liver Homeostasis and Regeneration

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.stem.2019.10.011
  
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FoxA1 and FoxA2 drive gastric differentiation and suppress squamous identity in NKX2-1-negative lung cancer

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1. scibot 13 Jan 2020
  
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  DOI: 10.7554/eLife.38579
  
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Untitled document

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  DOI: 10.1016/j.celrep.2019.02.035
  
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sciencedirect.com/science/article/pii/S2211124719302062
Nov 2018
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iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications

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1. scibot 05 Nov 2018
  
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The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment

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1. scibot 05 Nov 2018
  
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Untitled document

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onlinelibrary.wiley.com/doi/full/10.1002/jcb.27407
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Selective Inhibition of FOXO1 Activator/Repressor Balance Modulates Hepatic Glucose Handling

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Generation of human embryonic stem cell line with heterozygous RB1 deletion by CRIPSR/Cas9 nickase

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1. scibot 05 Nov 2018
  
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Intrinsic Immunity Shapes Viral Resistance of Stem Cells

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