40 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    FoxA1/2-dependent epigenomic reprogramming drives lineage switching in lung adenocarcinoma
    1
    1. scibot 11 Nov 2024
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      DOI: 10.1016/j.devcel.2024.10.009

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    sciencedirect.com/science/article/pii/S1534580724006282
  3. May 2024
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    Molecular subtypes of neuroendocrine carcinomas: A cross-tissue classification framework based on five transcriptional regulators
    1
    1. scibot 24 May 2024
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      DOI: 10.1016/j.ccell.2024.05.002

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    sciencedirect.com/science/article/pii/S1535610824001636
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    Modeling alcohol-associated liver disease in humans using adipose stromal or stem cell-derived organoids
    1
    1. scibot 16 May 2024
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      DOI: 10.1016/j.crmeth.2024.100778

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    sciencedirect.com/science/article/pii/S266723752400122X
  6. Apr 2024
  7. www.sciencedirect.com www.sciencedirect.com
    NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo
    1
    1. scibot 05 Apr 2024
      RRID:AB_2295208

      DOI: 10.1016/j.stem.2024.03.003

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    sciencedirect.com/science/article/pii/S1934590924000845
  8. Oct 2023
  9. www.sciencedirect.com www.sciencedirect.com
    Spatial-temporal proliferation of hepatocytes during pregnancy revealed by genetic lineage tracing
    1
    1. scibot 14 Oct 2023
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      DOI: 10.1016/j.stem.2023.09.002

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    sciencedirect.com/science/article/pii/S1934590923003235
  10. Jul 2023
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    Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation
    1
    1. scibot 27 Jul 2023
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      DOI: 10.1016/j.devcel.2023.07.001

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    sciencedirect.com/science/article/pii/S1534580723003313
  12. Jun 2023
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    Loss of Mettl3 enhances liver tumorigenesis by inducing hepatocyte dedifferentiation and hyperproliferation
    1
    1. scibot 28 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112704

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    sciencedirect.com/science/article/pii/S2211124723007155
  14. www.nature.com www.nature.com
    Genetic recording of in vivo cell proliferation by ProTracer
    1
    1. scibot 04 Jun 2023
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      DOI: 10.1038/s41596-023-00833-8

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    nature.com/articles/s41596-023-00833-8
  15. Mar 2023
  16. www.embopress.org www.embopress.org
    Two Hippo signaling modules orchestrate liver size and tumorigenesis
    2
    1. scibot 16 Mar 2023
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      DOI: 10.15252/embj.2022112126

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    2. scibot 16 Mar 2023
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      DOI: 10.15252/embj.2022112126

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    embopress.org/doi/10.15252/embj.2022112126
  17. www.sciencedirect.com www.sciencedirect.com
    Genotype-phenotype mapping of a patient-derived lung cancer organoid biobank identifies NKX2-1-defined Wnt dependency in lung adenocarcinoma
    1
    1. scibot 11 Mar 2023
      RRID:AB_2295208

      DOI: 10.1016/j.celrep.2023.112212

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    sciencedirect.com/science/article/pii/S2211124723002231
  18. Dec 2022
  19. www.sciencedirect.com www.sciencedirect.com
    Embryogenic stem cell-derived intestinal crypt fission directs de novo crypt genesis
    1
    1. scibot 18 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111796

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    sciencedirect.com/science/article/pii/S2211124722016849
  20. www.sciencedirect.com www.sciencedirect.com
    CRISPR/Cas9 mediated approach to generate YAP-depleted human embryonic stem cell line (MUSIe002-A-1)
    1
    1. scibot 06 Dec 2022
      AB_2295208

      DOI: 10.1016/j.scr.2022.102990

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    sciencedirect.com/science/article/pii/S1873506122003397
  21. Sep 2022
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A scalable and tunable thermoreversible polymer for 3D human pluripotent stem cell biomanufacturing
    1
    1. scibot 22 Sep 2022
      RRID:AB_2295208

      DOI: 10.1016/j.isci.2022.104971

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    ncbi.nlm.nih.gov/pmc/articles/PMC9485071/
  23. Aug 2022
  24. www.sciencedirect.com www.sciencedirect.com
    Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development
    1
    1. scibot 23 Aug 2022
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      DOI: 10.1016/j.isci.2022.104905

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    sciencedirect.com/science/article/pii/S2589004222011774
  25. Jul 2022
  26. www.sciencedirect.com www.sciencedirect.com
    FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma
    1
    1. scibot 15 Jul 2022
      RRID:AB_2295208

      DOI: 10.1016/j.devcel.2022.06.017

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    sciencedirect.com/science/article/pii/S1534580722004580
  27. Apr 2022
  28. www.sciencedirect.com www.sciencedirect.com
    The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes
    1
    1. scibot 22 Apr 2022
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      DOI: 10.1016/j.stem.2022.03.015

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    sciencedirect.com/science/article/pii/S1934590922001503
  29. www.sciencedirect.com www.sciencedirect.com
    WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy
    1
    1. scibot 20 Apr 2022
      RRID:AB_2295208

      DOI: 10.1016/j.molcel.2022.03.027

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    sciencedirect.com/science/article/pii/S1097276522002659
  30. Jan 2022
  31. www.sciencedirect.com www.sciencedirect.com
    Derivation of the MUSIe002-A human embryonic stem cell line
    1
    1. scibot 11 Jan 2022
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      DOI: 10.1016/j.scr.2022.102660

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    sciencedirect.com/science/article/pii/S1873506122000095
  32. Nov 2021
  33. www.sciencedirect.com www.sciencedirect.com
    Genome-wide screening in human kidney organoids identifies developmental and disease-related aspects of nephrogenesis
    1
    1. scibot 30 Nov 2021
      RRID:AB_2295208

      DOI: 10.1016/j.stem.2021.11.001

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    sciencedirect.com/science/article/pii/S1934590921004495
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modeling population size independent tissue epigenomes by ChIL‐seq with single thin sections
    1
    1. scibot 15 Nov 2021
      RRID:AB_2295208

      DOI: 10.15252/msb.202110323

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    ncbi.nlm.nih.gov/pmc/articles/PMC8564819/
  35. Sep 2021
  36. www.sciencedirect.com www.sciencedirect.com
    Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation
    1
    1. scibot 08 Sep 2021
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      DOI: 10.1016/j.celrep.2021.109659

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    sciencedirect.com/science/article/pii/S2211124721011037
  37. Jul 2021
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 30 Jul 2021
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      DOI: 10.1016/j.cell.2017.11.018

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    ncbi.nlm.nih.gov/pmc/articles/PMC5786493/
  39. www.sciencedirect.com www.sciencedirect.com
    Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors
    1
    1. scibot 07 Jul 2021
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      DOI: 10.1016/j.celrep.2021.109310

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    sciencedirect.com/science/article/pii/S2211124721006860
  40. May 2021
  41. www.sciencedirect.com www.sciencedirect.com
    A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting
    1
    1. scibot 09 May 2021
      RRID:AB_2295208

      DOI: 10.1016/j.stem.2021.01.007

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    sciencedirect.com/science/article/pii/S1934590921000072
  42. www.sciencedirect.com www.sciencedirect.com
    The Dynamics of Transcriptional Activation by Hepatic Reprogramming Factors
    1
    1. scibot 07 May 2021
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      DOI: 10.1016/j.molcel.2020.07.012

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    sciencedirect.com/science/article/pii/S1097276520305025
  43. Feb 2021
  44. www.cell.com www.cell.com
    Bookmarking by Non-pioneer Transcription Factors during Liver Development Establishes Competence for Future Gene Activation
    1
    1. scibot 24 Feb 2021
      RRID:AB_2295208

      DOI: 10.1016/j.celrep.2020.01.006

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    cell.com/cell-reports/abstract/S2211-1247(20)30015-2
  45. Dec 2020
  46. www.sciencedirect.com www.sciencedirect.com
    Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids
    1
    1. scibot 13 Dec 2020
      RRID:AB_2295208

      DOI: 10.1016/j.cels.2020.11.002

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    sciencedirect.com/science/article/pii/S2405471220304208
  47. Sep 2020
  48. www.cell.com www.cell.com
    Bookmarking by Non-pioneer Transcription Factors during Liver Development Establishes Competence for Future Gene Activation
    1
    1. scibot 26 Sep 2020
      RRID:AB_2295208

      DOI: 10.1016/j.celrep.2020.01.006

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    cell.com/cell-reports/abstract/S2211-1247(20)30015-2
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells
    1
    1. scibot 23 Sep 2020
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      DOI: 10.1038/s41419-020-2589-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC7235254/
  50. www.sciencedirect.com www.sciencedirect.com
    HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer
    1
    1. scibot 09 Sep 2020
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      DOI: 10.1016/j.celrep.2020.107625

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    sciencedirect.com/science/article/pii/S2211124720305787
  51. Jan 2020
  52. www.sciencedirect.com www.sciencedirect.com
    AXIN2+ Pericentral Hepatocytes Have Limited Contributions to Liver Homeostasis and Regeneration
    1
    1. scibot 13 Jan 2020
      RRID:AB_2295208

      DOI: 10.1016/j.stem.2019.10.011

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    sciencedirect.com/science/article/pii/S1934590919304321
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FoxA1 and FoxA2 drive gastric differentiation and suppress squamous identity in NKX2-1-negative lung cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_2295208

      DOI: 10.7554/eLife.38579

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    ncbi.nlm.nih.gov/pmc/articles/PMC6303105/
  54. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.celrep.2019.02.035

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    sciencedirect.com/science/article/pii/S2211124719302062
  55. Nov 2018
  56. www.sciencedirect.com www.sciencedirect.com
    iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications
    1
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      3113S

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    sciencedirect.com/science/article/pii/S0092867418302903
  57. www.sciencedirect.com www.sciencedirect.com
    The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment
    1
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    sciencedirect.com/science/article/pii/S1074761318304357
  58. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    1. scibot 05 Nov 2018
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    onlinelibrary.wiley.com/doi/full/10.1002/jcb.27407
  59. www.sciencedirect.com www.sciencedirect.com
    Selective Inhibition of FOXO1 Activator/Repressor Balance Modulates Hepatic Glucose Handling
    1
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    sciencedirect.com/science/article/pii/S009286741731139X
  60. www.sciencedirect.com www.sciencedirect.com
    Generation of human embryonic stem cell line with heterozygous RB1 deletion by CRIPSR/Cas9 nickase
    1
    1. scibot 05 Nov 2018
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      Curator: @evieth

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    sciencedirect.com/science/article/pii/S1873506118300278
  61. www.sciencedirect.com www.sciencedirect.com
    Intrinsic Immunity Shapes Viral Resistance of Stem Cells
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    sciencedirect.com/science/article/pii/S009286741731365X