Hypothesis

17 Matching Annotations

Jan 2026
www.sciencedirect.com www.sciencedirect.com

Inhibition of PAK2 in endothelial cells suppresses tumor angiogenesis and promotes immune sensitization through CXCL10

1
1. scibot 06 Jan 2026
  
  in Public
  
  RRID:AB_2299279
  
  DOI: 10.1016/j.celrep.2025.116840
  
  Resource: (Cell Signaling Technology Cat# 2606, RRID:AB_2299279)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2299279
  
  What is this?
  
  RRID:AB_2299279
Visit annotations in context

Tags

RRID:AB_2299279

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124725016122
May 2025
www.sciencedirect.com www.sciencedirect.com

An integrated proteomics approach identifies phosphorylation sites on viral and host proteins that regulate West Nile virus infection

1
1. scibot 17 May 2025
  
  in Public
  
  RRID:AB_2299279
  
  DOI: 10.1016/j.celrep.2025.115728
  
  Resource: (Cell Signaling Technology Cat# 2606, RRID:AB_2299279)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2299279
  
  What is this?
  
  RRID:AB_2299279
Visit annotations in context

Tags

RRID:AB_2299279

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124725004991
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells

1
1. scibot 23 Aug 2024
  
  in Public
  
  RRID:AB_2299279
  
  DOI: 10.7554/eLife.76940
  
  Resource: (Cell Signaling Technology Cat# 2606, RRID:AB_2299279)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2299279
  
  What is this?
  
  RRID:AB_2299279
Visit annotations in context

Tags

RRID:AB_2299279

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11333044/
Jul 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Loss of the polarity protein Par3 promotes dendritic spine neoteny and enhances learning and memory

1
1. scibot 18 Jul 2024
  
  in Public
  
  AB_2299279
  
  DOI: 10.1016/j.isci.2024.110308
  
  Resource: (Cell Signaling Technology Cat# 2606, RRID:AB_2299279)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2299279
  
  What is this?
  
  RRID:AB_2299279
Visit annotations in context

Tags

RRID:AB_2299279

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11263792/
Jan 2024
www.science.org www.science.org

RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling

3
1. scibot 20 Jan 2024
  
  in Public
  
  AB_2299279
  
  DOI: 10.1126/scisignal.adg5289
  
  Resource: (Cell Signaling Technology Cat# 2606, RRID:AB_2299279)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2299279
  
  What is this?
  
  RRID:AB_2299279
2. scibot 12 Jan 2024
  
  in Public
  
  AB_2299279
  
  DOI: 10.1126/scisignal.adg5289
  
  Resource: (Cell Signaling Technology Cat# 2606, RRID:AB_2299279)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2299279
  
  What is this?
  
  RRID:AB_2299279
3. scibot 12 Jan 2024
  
  in Public
  
  AB_2299279
  
  DOI: 10.1126/scisignal.adg5289
  
  Resource: (Cell Signaling Technology Cat# 2606, RRID:AB_2299279)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2299279
  
  What is this?
  
  RRID:AB_2299279
Visit annotations in context

Tags

RRID:AB_2299279

Annotators

scibot

URL

science.org/doi/10.1126/scisignal.adg5289
Nov 2023
www.sciencedirect.com www.sciencedirect.com

PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis

1
1. scibot 28 Nov 2023
  
  in Public
  
  RRID:AB_2299279
  
  DOI: 10.1016/j.celrep.2023.113414
  
  Resource: (Cell Signaling Technology Cat# 2606, RRID:AB_2299279)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2299279
  
  What is this?
  
  RRID:AB_2299279
Visit annotations in context

Tags

RRID:AB_2299279

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723014262
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The Evaluation of Rac1 Signaling as a Potential Therapeutic Target of Alzheimer’s Disease

1
1. scibot 16 Aug 2023
  
  in Public
  
  RRID:AB_2299279
  
  DOI: 10.3390/ijms241511880
  
  Resource: (Cell Signaling Technology Cat# 2606, RRID:AB_2299279)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2299279
  
  What is this?
  
  RRID:AB_2299279
Visit annotations in context

Tags

RRID:AB_2299279

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10418761/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PAK1 contributes to cerebral ischemia/reperfusion injury by regulating the blood-brain barrier integrity

1
1. scibot 02 Aug 2023
  
  in Public
  
  RRID:AB_2299279
  
  DOI: 10.1016/j.isci.2023.107333
  
  Resource: (Cell Signaling Technology Cat# 2606, RRID:AB_2299279)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2299279
  
  What is this?
  
  RRID:AB_2299279
Visit annotations in context

Tags

RRID:AB_2299279

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10387573/
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways

1
1. scibot 21 Jun 2023
  
  in Public
  
  RRID:AB_2299279
  
  DOI: 10.1016/j.cmet.2023.05.007
  
  Resource: (Cell Signaling Technology Cat# 2606, RRID:AB_2299279)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2299279
  
  What is this?
  
  RRID:AB_2299279
Visit annotations in context

Tags

RRID:AB_2299279

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413123001845
Jun 2022
www.nature.com www.nature.com

Phosphoproteomic of the acetylcholine pathway enables discovery of the PKC-β-PIX-Rac1-PAK cascade as a stimulatory signal for aversive learning

1
1. scibot 04 Jun 2022
  
  in Public
  
  RRID:AB_2299279
  
  DOI: 10.1038/s41380-022-01643-2
  
  Resource: (Cell Signaling Technology Cat# 2606, RRID:AB_2299279)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2299279
  
  What is this?
  
  RRID:AB_2299279
Visit annotations in context

Tags

RRID:AB_2299279

Annotators

scibot

URL

nature.com/articles/s41380-022-01643-2
Apr 2022
www.sciencedirect.com www.sciencedirect.com

Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation

1
1. scibot 13 Apr 2022
  
  in Public
  
  RRID:AB_2299279
  
  DOI: 10.1016/j.molcel.2022.03.026
  
  Resource: (Cell Signaling Technology Cat# 2606, RRID:AB_2299279)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2299279
  
  What is this?
  
  RRID:AB_2299279
Visit annotations in context

Tags

RRID:AB_2299279

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276522002647
Jul 2021
mbio.asm.org mbio.asm.org

Pathogenic Escherichia coli Hijacks GTPase-Activated p21-Activated Kinase for Actin Pedestal Formation

1
1. scibot 29 Jul 2021
  
  in Public
  
  phospho-PAK1 [Ser144]/PAK2 [Ser141]
  
  DOI: 10.1128/mBio.01876-19
  
  Resource: (Cell Signaling Technology Cat# 2606, RRID:AB_2299279)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2299279
  
  What is this?
  
  RRID:AB_2299279 RRIDCUR:Missing
Visit annotations in context

Tags

RRID:AB_2299279

RRIDCUR:Missing

Annotators

scibot

URL

mbio.asm.org/content/10/4/e01876-19
Jan 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mice carrying a schizophrenia-associated mutation of the Arhgap10 gene are vulnerable to the effects of methamphetamine treatment on cognitive function: association with morphological abnormalities in striatal neurons

1
1. scibot 28 Jan 2021
  
  in Public
  
  RRID:AB_2299279
  
  DOI: 10.1186/s13041-021-00735-4
  
  Resource: (Cell Signaling Technology Cat# 2606, RRID:AB_2299279)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2299279
  
  What is this?
  
  RRID:AB_2299279 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_2299279

RRIDCUR:Validated

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7821731/
Jan 2020
www.sciencedirect.com www.sciencedirect.com

EGFR-Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2299279
  
  DOI: 10.1016/j.devcel.2019.05.043
  
  Resource: (Cell Signaling Technology Cat# 2606, RRID:AB_2299279)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2299279
  
  What is this?
  
  RRID:AB_2299279 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_2299279

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S153458071930485X
Nov 2017
elifesciences.org elifesciences.org

p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_2299279
  
  Curator: @kaitlinsung
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2606S, RRID:AB_2299279)
  
  SciCrunch record: RRID:AB_2299279
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2299279 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_2299279

RRIDCUR:Validated

Annotators

scibot

URL

elifesciences.org/content/6/e22207