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  1. Last 7 days
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    The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation
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    1. scibot 14 May 2024
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    sciencedirect.com/science/article/pii/S1074761324002218
  3. Apr 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Edaravone Dexborneol mitigates pathology in animal and cell culture models of Alzheimer’s disease by inhibiting neuroinflammation and neuronal necroptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11056062/
  5. Mar 2024
  6. 52.53.155.43 52.53.155.43
    NLRP6 induces RIP1 kinase-dependent necroptosis via TAK1-mediated p38MAPK/MK2 phosphorylation in S. Typhimurium infection
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    1. scibot 08 Mar 2024
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    52.53.155.43/edc059b1f8d2daaa9b02a6bfc9253e0bab800af6/1-s2.0-S2589004224005601-main-html.html
  7. Feb 2024
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    PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression
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    sciencedirect.com/science/article/pii/S1550413124000056
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    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells
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    1. scibot 03 Feb 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10831336/
  10. Jan 2024
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    PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis
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    1. scibot 25 Jan 2024
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    Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells
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    1. scibot 19 Jan 2024
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    sciencedirect.com/science/article/pii/S2666379123006067
  13. Dec 2023
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    Analysis of multiple programmed cell death-related prognostic genes and functional validations of necroptosis-associated genes in oesophageal squamous cell carcinoma
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    1. scibot 16 Dec 2023
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    sciencedirect.com/science/article/pii/S2352396423004863
  15. Nov 2023
  16. www.biorxiv.org www.biorxiv.org
    An immunohistochemical atlas of necroptotic pathway expression
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    1. scibot 10 Nov 2023
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      DOI: 10.1101/2023.10.31.565039

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    biorxiv.org/content/10.1101/2023.10.31.565039v1
  17. Oct 2023
  18. 52.53.155.43 52.53.155.43
    BPS Publications
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    1. scibot 06 Oct 2023
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    52.53.155.43/6079453bbbf12bd08872d5439d37d8b14bece994/British J Pharmacology - 2023 - Chen - DADLE promotes motor function recovery by inhibiting cytosolic phospholipase A2-html.html
  19. Sep 2023
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic Carbon Disulfide Exposure Induces Parkinsonian Pathology via α-Synuclein Aggregation and Necrosome Complex Interaction
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    1. scibot 22 Sep 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10507234/
  21. Aug 2023
  22. www.nature.com www.nature.com
    Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2
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    1. scibot 01 Aug 2023
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    nature.com/articles/s41594-023-01044-1
  23. Jul 2023
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    Nucleoporin Seh1 maintains Schwann cell homeostasis by regulating genome stability and necroptosis
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    1. scibot 21 Jul 2023
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    sciencedirect.com/science/article/pii/S2211124723008136
  25. Apr 2023
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    PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1
    1
    1. scibot 08 Apr 2023
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    sciencedirect.com/science/article/pii/S2211124723003510
  27. Feb 2023
  28. www.sciencedirect.com www.sciencedirect.com
    Direct activation of microglia by β-glucosylceramide causes phagocytosis of neurons that exacerbates Gaucher disease
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    sciencedirect.com/science/article/pii/S1074761323000183
  29. Jan 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D pore-forming activity is redox-sensitive
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    sciencedirect.com/science/article/pii/S2211124723000190
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    SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD
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      DOI: 10.1016/j.celrep.2022.111961

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    sciencedirect.com/science/article/pii/S2211124722018654
  32. Oct 2022
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIRPα maintains macrophage homeostasis by interacting with PTK2B kinase in Mycobacterium tuberculosis infection and through autophagy and necroptosis
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    1. scibot 12 Oct 2022
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    ncbi.nlm.nih.gov/pmc/articles/PMC9535427/
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    Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation
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    sciencedirect.com/science/article/pii/S221112472201275X
  35. Aug 2022
  36. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis
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    sciencedirect.com/science/article/pii/S0092867422007905
  37. Jul 2022
  38. www.sciencedirect.com www.sciencedirect.com
    Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death
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    sciencedirect.com/science/article/pii/S258900422200904X
  39. Jun 2022
  40. www.sciencedirect.com www.sciencedirect.com
    RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells
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    sciencedirect.com/science/article/pii/S2666379122001872
  41. Oct 2021
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    Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains
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    sciencedirect.com/science/article/pii/S2211124721012316
  43. Sep 2021
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD4+ T cell-mimicking nanoparticles encapsulating DIABLO/SMAC mimetics broadly neutralize HIV-1 and selectively kill HIV-1-infected cells
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      DOI: 10.7150/thno.59728

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    ncbi.nlm.nih.gov/pmc/articles/PMC8419049/
  45. Aug 2021
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma
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      DOI: 10.1158/1078-0432.CCR-18-3683

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    ncbi.nlm.nih.gov/pmc/articles/PMC7887036/
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    Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death
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    sciencedirect.com/science/article/pii/S0092867421008850
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    Axonal Activation of the Unfolded Protein Response Promotes Axonal Regeneration Following Peripheral Nerve Injury
    1
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    sciencedirect.com/science/article/pii/S0306452218301118
  49. Jul 2021
  50. www.sciencedirect.com www.sciencedirect.com
    A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development
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    1. scibot 28 Jul 2021
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    sciencedirect.com/science/article/pii/S1535610817303549
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    Axonal Activation of the Unfolded Protein Response Promotes Axonal Regeneration Following Peripheral Nerve Injury
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    sciencedirect.com/science/article/pii/S0306452218301118
  52. May 2021
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes prostaglandin2α-induced corpus luteum regression
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    1. scibot 28 May 2021
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      DOI: 10.7554/eLife.67409

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    ncbi.nlm.nih.gov/pmc/articles/PMC8143796/
  54. www.sciencedirect.com www.sciencedirect.com
    RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis
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    sciencedirect.com/science/article/pii/S2211124721004460
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    A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade
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      DOI: 10.1016/j.molcel.2020.09.004

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    sciencedirect.com/science/article/pii/S1097276520306122
  56. Apr 2021
  57. www.sciencedirect.com www.sciencedirect.com
    Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells
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      DOI: 10.1016/j.cmet.2020.10.017

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    sciencedirect.com/science/article/pii/S1550413120305507
  58. Dec 2020
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes
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    1. scibot 10 Dec 2020
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      DOI: 10.1016/j.cell.2020.11.025

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    ncbi.nlm.nih.gov/pmc/articles/PMC7674074/
  60. Nov 2020
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Casein kinase 1G2 suppresses necroptosis-promoted testis aging by inhibiting receptor-interacting kinase 3
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    1. scibot 26 Nov 2020
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      DOI: 10.7554/eLife.61564

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    ncbi.nlm.nih.gov/pmc/articles/PMC7673785/
  62. Sep 2020
  63. www.sciencedirect.com www.sciencedirect.com
    The Autophagy-Initiating Kinase ULK1 Controls RIPK1-Mediated Cell Death
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      DOI: 10.1016/j.celrep.2020.107547

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    sciencedirect.com/science/article/pii/S2211124720304575
  64. www.cell.com www.cell.com
    Survival of Single Positive Thymocytes Depends upon Developmental Control of RIPK1 Kinase Signaling by the IKK Complex Independent of NF-κB
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      DOI: 10.1016/j.immuni.2019.01.004

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    cell.com/immunity/abstract/S1074-7613(19)30004-4
  65. www.sciencedirect.com www.sciencedirect.com
    OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis
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    sciencedirect.com/science/article/pii/S2211124720300371
  66. www.sciencedirect.com www.sciencedirect.com
    Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
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    1. scibot 17 Sep 2020
      RRID:AB_2305314

      DOI: 10.1016/j.cell.2020.03.040

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    sciencedirect.com/science/article/pii/S0092867420303330
  67. www.sciencedirect.com www.sciencedirect.com
    Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis
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    1. scibot 16 Sep 2020
      RRID:AB_2305314

      DOI: 10.1016/j.immuni.2020.02.007

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    sciencedirect.com/science/article/pii/S1074761320300789
  68. www.nature.com www.nature.com
    Necroptosis in head and neck squamous cell carcinoma: characterization of clinicopathological relevance and in vitro cell model
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      RRID:AB_2305314

      DOI: 10.1038/s41419-020-2538-5

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      Curator: @evieth

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  69. www.sciencedirect.com www.sciencedirect.com
    Constitutive Interferon Attenuates RIPK1/3-Mediated Cytokine Translation
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    1. scibot 03 Sep 2020
      RRID:AB_2305314

      DOI: 10.1016/j.celrep.2019.12.073

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    sciencedirect.com/science/article/pii/S2211124719317309
  70. Jan 2020
  71. www.sciencedirect.com www.sciencedirect.com
    TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL
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      RRID:AB_2305314

      DOI: 10.1016/j.molcel.2019.05.022

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    sciencedirect.com/science/article/pii/S1097276519303946
  72. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3
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    1. scibot 13 Jan 2020
      RRID:AB_2305314

      DOI: 10.1016/j.immuni.2019.01.007

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    sciencedirect.com/science/article/pii/S1074761319300305
  73. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 12 Jan 2020
      RRID:AB_2305314

      DOI: 10.1016/j.immuni.2019.01.004

      Resource: (Cell Signaling Technology Cat# 3493, RRID:AB_2305314)

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    sciencedirect.com/science/article/pii/S1074761319300044
  74. Nov 2018
  75. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      RRID:AB_2305314

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1931312818304918
  76. www.sciencedirect.com www.sciencedirect.com
    TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
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    1. scibot 05 Nov 2018
      RRID:AB_2305314

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      RRID:AB_2305314
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    sciencedirect.com/science/article/pii/S0092867418309693