62 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Residue Y362 is crucial for FLIPL to impart catalytic activity to pro-caspase-8 to suppress necroptosis
    1
    1. scibot 11 Nov 2024
      RRID:AB_2305314

      DOI: 10.1016/j.celrep.2024.114966

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    sciencedirect.com/science/article/pii/S2211124724013172
  3. Oct 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Rift Valley fever virus coordinates the assembly of a programmable E3 ligase to promote viral replication
    1
    1. scibot 04 Oct 2024
      AB_2305314

      DOI: 10.1016/j.cell.2024.09.008

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    sciencedirect.com/science/article/pii/S0092867424010262
  5. Sep 2024
  6. www.nature.com www.nature.com
    Activation of the NLRP1B inflammasome by caspase-8
    1
    1. scibot 25 Sep 2024
      RRID:AB_2305314

      DOI: 10.1038/s42003-024-06882-3

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    nature.com/articles/s42003-024-06882-3
  7. www.sciencedirect.com www.sciencedirect.com
    Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis
    1
    1. scibot 11 Sep 2024
      RRID:AB_2305314

      DOI: 10.1016/j.celrep.2024.114728

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    sciencedirect.com/science/article/pii/S2211124724010799
  8. www.sciencedirect.com www.sciencedirect.com
    CD14 is a decision-maker between Fas-mediated death and inflammation
    1
    1. scibot 04 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114685

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    sciencedirect.com/science/article/pii/S2211124724010362
  9. Aug 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection
    1
    1. scibot 22 Aug 2024
      RRID:AB_2305314

      DOI: 10.1016/j.celrep.2024.114641

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    sciencedirect.com/science/article/pii/S2211124724009914
  11. www.sciencedirect.com www.sciencedirect.com
    Protocol for analyzing TRAIL- and Fas-induced signaling complexes by immunoprecipitation from human cells
    1
    1. scibot 19 Aug 2024
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      DOI: 10.1016/j.xpro.2024.103126

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    sciencedirect.com/science/article/pii/S2666166724002910
  12. www.cell.com www.cell.com
    RIPK1 Promotes Energy Sensing by the mTORC1 Pathway
    1
    1. scibot 02 Aug 2024
      RIPK1

      DOI: 10.1016/j.molcel.2020.11.008

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    cell.com/molecular-cell/fulltext/S1097-2765(20)30786-3
  13. Jul 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Targeting type I DED interactions at the DED filament serves as a sensitive switch for cell fate decisions
    1
    1. scibot 25 Jul 2024
      RRID:AB_2305314

      DOI: 10.1016/j.chembiol.2024.06.014

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    sciencedirect.com/science/article/pii/S2451945624002745
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An immunohistochemical atlas of necroptotic pathway expression
    1
    1. scibot 18 Jul 2024
      RRID:AB_2305314

      DOI: 10.1038/s44321-024-00074-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11250867/
  16. www.cell.com www.cell.com
    Extracellular vesicles from alveolar macrophages harboring phagocytosed methicillin-resistant Staphylococcus aureus induce necroptosis
    1
    1. scibot 12 Jul 2024
      RRID:AB_2305314

      DOI: 10.1016/j.celrep.2024.114453

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    cell.com/cell-reports/fulltext/S2211-1247(24)00782-4
  17. Jun 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The interaction between RIPK1 and FADD controls perinatal lethality and inflammation
    1
    1. scibot 21 Jun 2024
      RRID:AB_2305314

      DOI: 10.1016/j.celrep.2024.114335

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    ncbi.nlm.nih.gov/pmc/articles/PMC11256114/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hippo-PKCζ-NFκB signaling axis: A druggable modulator of chondrocyte responses to mechanical stress
    1
    1. scibot 03 Jun 2024
      RRID:AB_2305314

      DOI: 10.1016/j.isci.2024.109983

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    ncbi.nlm.nih.gov/pmc/articles/PMC11140209/
  20. May 2024
  21. www.sciencedirect.com www.sciencedirect.com
    A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
    1
    1. scibot 24 May 2024
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      DOI: 10.1016/j.immuni.2024.04.025

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    sciencedirect.com/science/article/pii/S1074761324002309
  22. www.sciencedirect.com www.sciencedirect.com
    The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation
    1
    1. scibot 14 May 2024
      Cat# 3493, RRID:AB_2305314

      DOI: 10.1016/j.immuni.2024.04.016

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    sciencedirect.com/science/article/pii/S1074761324002218
  23. Apr 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Edaravone Dexborneol mitigates pathology in animal and cell culture models of Alzheimer’s disease by inhibiting neuroinflammation and neuronal necroptosis
    1
    1. scibot 30 Apr 2024
      RRID:AB_2305314

      DOI: 10.1186/s13578-024-01230-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC11056062/
  25. Mar 2024
  26. 52.53.155.43 52.53.155.43
    NLRP6 induces RIP1 kinase-dependent necroptosis via TAK1-mediated p38MAPK/MK2 phosphorylation in S. Typhimurium infection
    1
    1. scibot 08 Mar 2024
      AB_2305314

      DOI: 10.1016/j.isci.2024.109339

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    52.53.155.43/edc059b1f8d2daaa9b02a6bfc9253e0bab800af6/1-s2.0-S2589004224005601-main-html.html
  27. Feb 2024
  28. www.sciencedirect.com www.sciencedirect.com
    PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression
    1
    1. scibot 06 Feb 2024
      RRID:AB_2305314

      DOI: 10.1016/j.cmet.2024.01.006

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    sciencedirect.com/science/article/pii/S1550413124000056
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells
    1
    1. scibot 03 Feb 2024
      RRID:AB_2305314

      DOI: 10.1158/0008-5472.CAN-23-1632

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    ncbi.nlm.nih.gov/pmc/articles/PMC10831336/
  30. Jan 2024
  31. www.sciencedirect.com www.sciencedirect.com
    PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis
    1
    1. scibot 25 Jan 2024
      RRID:AB_2305314

      DOI: 10.1016/j.molcel.2023.12.041

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    sciencedirect.com/science/article/pii/S1097276523011218
  32. www.sciencedirect.com www.sciencedirect.com
    Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells
    1
    1. scibot 19 Jan 2024
      RRID:AB_2305314

      DOI: 10.1016/j.xcrm.2023.101377

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    sciencedirect.com/science/article/pii/S2666379123006067
  33. Dec 2023
  34. www.sciencedirect.com www.sciencedirect.com
    Analysis of multiple programmed cell death-related prognostic genes and functional validations of necroptosis-associated genes in oesophageal squamous cell carcinoma
    1
    1. scibot 16 Dec 2023
      RRID:AB_2305314

      DOI: 10.1016/j.ebiom.2023.104920

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    sciencedirect.com/science/article/pii/S2352396423004863
  35. Nov 2023
  36. www.biorxiv.org www.biorxiv.org
    An immunohistochemical atlas of necroptotic pathway expression
    1
    1. scibot 10 Nov 2023
      RRID:AB_2305314

      DOI: 10.1101/2023.10.31.565039

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    biorxiv.org/content/10.1101/2023.10.31.565039v1
  37. Oct 2023
  38. 52.53.155.43 52.53.155.43
    BPS Publications
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    1. scibot 06 Oct 2023
      RRID:AB_2305314

      DOI: 10.1111/bph.16255

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    52.53.155.43/6079453bbbf12bd08872d5439d37d8b14bece994/British J Pharmacology - 2023 - Chen - DADLE promotes motor function recovery by inhibiting cytosolic phospholipase A2-html.html
  39. Sep 2023
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic Carbon Disulfide Exposure Induces Parkinsonian Pathology via α-Synuclein Aggregation and Necrosome Complex Interaction
    1
    1. scibot 22 Sep 2023
      RRID:AB_2305314

      DOI: 10.1016/j.isci.2023.107787

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    ncbi.nlm.nih.gov/pmc/articles/PMC10507234/
  41. Aug 2023
  42. www.nature.com www.nature.com
    Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2
    1
    1. scibot 01 Aug 2023
      RRID:AB_2305314

      DOI: 10.1038/s41594-023-01044-1

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    nature.com/articles/s41594-023-01044-1
  43. Jul 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Nucleoporin Seh1 maintains Schwann cell homeostasis by regulating genome stability and necroptosis
    1
    1. scibot 21 Jul 2023
      RRID:AB_2305314

      DOI: 10.1016/j.celrep.2023.112802

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    sciencedirect.com/science/article/pii/S2211124723008136
  45. Apr 2023
  46. www.sciencedirect.com www.sciencedirect.com
    PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1
    1
    1. scibot 08 Apr 2023
      RRID:AB_2305314

      DOI: 10.1016/j.celrep.2023.112340

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    sciencedirect.com/science/article/pii/S2211124723003510
  47. Feb 2023
  48. www.sciencedirect.com www.sciencedirect.com
    Direct activation of microglia by β-glucosylceramide causes phagocytosis of neurons that exacerbates Gaucher disease
    1
    1. scibot 03 Feb 2023
      RRID:AB_2305314

      DOI: 10.1016/j.immuni.2023.01.008

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    sciencedirect.com/science/article/pii/S1074761323000183
  49. Jan 2023
  50. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D pore-forming activity is redox-sensitive
    1
    1. scibot 21 Jan 2023
      RRID:AB_2305314

      DOI: 10.1016/j.celrep.2023.112008

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    sciencedirect.com/science/article/pii/S2211124723000190
  51. www.sciencedirect.com www.sciencedirect.com
    SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD
    1
    1. scibot 19 Jan 2023
      RRID:AB_2305314

      DOI: 10.1016/j.celrep.2022.111961

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    sciencedirect.com/science/article/pii/S2211124722018654
  52. Oct 2022
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIRPα maintains macrophage homeostasis by interacting with PTK2B kinase in Mycobacterium tuberculosis infection and through autophagy and necroptosis
    1
    1. scibot 12 Oct 2022
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      DOI: 10.1016/j.ebiom.2022.104278

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    ncbi.nlm.nih.gov/pmc/articles/PMC9535427/
  54. www.sciencedirect.com www.sciencedirect.com
    Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation
    1
    1. scibot 05 Oct 2022
      RRID:AB_2305314

      DOI: 10.1016/j.celrep.2022.111434

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    sciencedirect.com/science/article/pii/S221112472201275X
  55. Aug 2022
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis
    1
    1. scibot 02 Aug 2022
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      DOI: 10.1016/j.cell.2022.06.038

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    ncbi.nlm.nih.gov/pmc/articles/PMC9531054/
  57. Jul 2022
  58. www.sciencedirect.com www.sciencedirect.com
    Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death
    1
    1. scibot 08 Jul 2022
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      DOI: 10.1016/j.isci.2022.104632

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    sciencedirect.com/science/article/pii/S258900422200904X
  59. Jun 2022
  60. www.sciencedirect.com www.sciencedirect.com
    RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells
    1
    1. scibot 10 Jun 2022
      RRID:AB_2305314

      DOI: 10.1016/j.xcrm.2022.100655

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    sciencedirect.com/science/article/pii/S2666379122001872
  61. Oct 2021
  62. www.sciencedirect.com www.sciencedirect.com
    Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains
    1
    1. scibot 06 Oct 2021
      RRID:AB_2305314

      DOI: 10.1016/j.celrep.2021.109777

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    sciencedirect.com/science/article/pii/S2211124721012316
  63. Sep 2021
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD4+ T cell-mimicking nanoparticles encapsulating DIABLO/SMAC mimetics broadly neutralize HIV-1 and selectively kill HIV-1-infected cells
    1
    1. scibot 18 Sep 2021
      RRID:AB_2305314

      DOI: 10.7150/thno.59728

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    ncbi.nlm.nih.gov/pmc/articles/PMC8419049/
  65. Aug 2021
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma
    1
    1. scibot 17 Aug 2021
      RRID:AB_2305314

      DOI: 10.1158/1078-0432.CCR-18-3683

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  67. www.sciencedirect.com www.sciencedirect.com
    Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death
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    Axonal Activation of the Unfolded Protein Response Promotes Axonal Regeneration Following Peripheral Nerve Injury
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  69. Jul 2021
  70. www.sciencedirect.com www.sciencedirect.com
    A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development
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  71. www.sciencedirect.com www.sciencedirect.com
    Axonal Activation of the Unfolded Protein Response Promotes Axonal Regeneration Following Peripheral Nerve Injury
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  72. May 2021
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes prostaglandin2α-induced corpus luteum regression
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  74. www.sciencedirect.com www.sciencedirect.com
    RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis
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    A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade
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  76. Apr 2021
  77. www.sciencedirect.com www.sciencedirect.com
    Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells
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    sciencedirect.com/science/article/pii/S1550413120305507
  78. Dec 2020
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes
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  80. Nov 2020
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Casein kinase 1G2 suppresses necroptosis-promoted testis aging by inhibiting receptor-interacting kinase 3
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  82. Sep 2020
  83. www.sciencedirect.com www.sciencedirect.com
    The Autophagy-Initiating Kinase ULK1 Controls RIPK1-Mediated Cell Death
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  84. www.cell.com www.cell.com
    Survival of Single Positive Thymocytes Depends upon Developmental Control of RIPK1 Kinase Signaling by the IKK Complex Independent of NF-κB
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      DOI: 10.1016/j.immuni.2019.01.004

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  85. www.sciencedirect.com www.sciencedirect.com
    OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis
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    Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
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      DOI: 10.1016/j.cell.2020.03.040

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    Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis
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    sciencedirect.com/science/article/pii/S1074761320300789
  88. www.nature.com www.nature.com
    Necroptosis in head and neck squamous cell carcinoma: characterization of clinicopathological relevance and in vitro cell model
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      DOI: 10.1038/s41419-020-2538-5

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    nature.com/articles/s41419-020-2538-5
  89. www.sciencedirect.com www.sciencedirect.com
    Constitutive Interferon Attenuates RIPK1/3-Mediated Cytokine Translation
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      RRID:AB_2305314

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    sciencedirect.com/science/article/pii/S2211124719317309
  90. Jan 2020
  91. www.sciencedirect.com www.sciencedirect.com
    TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL
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      RRID:AB_2305314

      DOI: 10.1016/j.molcel.2019.05.022

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    sciencedirect.com/science/article/pii/S1097276519303946
  92. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3
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    1. scibot 13 Jan 2020
      RRID:AB_2305314

      DOI: 10.1016/j.immuni.2019.01.007

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    sciencedirect.com/science/article/pii/S1074761319300305
  93. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 12 Jan 2020
      RRID:AB_2305314

      DOI: 10.1016/j.immuni.2019.01.004

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    sciencedirect.com/science/article/pii/S1074761319300044
  94. Nov 2018
  95. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S1931312818304918
  96. www.sciencedirect.com www.sciencedirect.com
    TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
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