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    Protein profile of mouse endolymph suggests a role in controlling cochlear homeostasis
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    Profound synthetic lethality between SMARCAL1 and FANCM
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    Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair
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  5. Nov 2024
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    Differential contributions of fetal mononuclear phagocytes to Zika virus neuroinvasion versus neuroprotection during congenital infection
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    Insulin Mediates Lipopolysaccharide-Induced Inflammatory Responses and Oxidative Stress in BV2 Microglia
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    Dynamic roles of neutrophil extracellular traps in cancer cell adhesion and activation of Notch 1-mediated epithelial-to-mesenchymal transition in EGFR-driven lung cancer cells
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  9. Oct 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Moesin contributes to heat shock gene response through direct binding to the Med15 subunit of the Mediator complex in the nucleus
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    CTNND2 moderates the pace of synaptic maturation and links human evolution to synaptic neoteny
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    RNA polymerase II transcription initiation in holo-TFIID-depleted mouse embryonic stem cells
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    Alzheimer’s disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model
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  14. Sep 2024
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    LM11a-31 Inhibits p75 Neurotrophin Receptor (p75NTR) Cleavage and is Neuroprotective in a Cell Culture Model of Parkinson’s Disease
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    ProSAAS is preferentially up-regulated during homeostatic scaling and reduces amyloid plaque burden in the 5xFAD mouse hippocampus
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    Atypical cellular responses mediated by intracellular constitutive active TrkB (NTRK2) kinase domains and a solely intracellular NTRK2-fusion oncogene
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    “β-Hydroxybutyrate Recapitulates the Beneficial Effects of Ketogenic Metabolic Therapy in Polycystic Kidney Disease”
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    Microbiota regulates neonatal disease tolerance to virus-evoked necrotizing enterocolitis by shaping the STAT1-NLRC5 axis in the intestinal epithelium
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    Cannabinoid combination targets NOTCH1-mutated T-cell acute lymphoblastic leukemia through the integrated stress response pathway
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    S-acylation of NLRP3 provides a nigericin sensitive gating mechanism that controls access to the Golgi
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    Input-specific localization of NMDA receptor GluN2 subunits in thalamocortical neurons
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    Dynamic remodeling of Septin structures fine-tunes myogenic differentiation
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  24. Aug 2024
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    Non-canonical function of ADAM10 in presynaptic plasticity
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    Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation
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    Identification of the zebrafish homologues of IMPG2, a retinal proteoglycan
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    Galactosidase-catalyzed fluorescence amplification method (GAFAM): sensitive fluorescent immunohistochemistry using novel fluorogenic β-galactosidase substrates and its application in multiplex immunostaining
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  29. journals.physiology.org journals.physiology.org
    Progesterone and estrogen regulate NALCN expression in human myometrial smooth muscle cells | American Journal of Physiology-Endocrinology and Metabolism
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    A Brucella effector modulates the Arf6-Rab8a GTPase cascade to promote intravacuolar replication
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  31. Jul 2024
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    A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins
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    Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral sensitization
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    Exosomal miRNA 16-5p/29a-3p from pancreatic cancer induce adipose atrophy by inhibiting adipogenesis and promoting lipolysis
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    Inhalation of hydrogen gas mitigates sevoflurane-induced neuronal apoptosis in the neonatal cortex and is associated with changes in protein phosphorylation
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  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Wnt/β-catenin signaling within multiple cell types dependent upon kramer regulates Drosophila intestinal stem cell proliferation
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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A phosphorylation-controlled switch confers cell cycle-dependent protein relocalization
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  38. Jun 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetyl-NPKY of Integrin-beta 1 binds KINDLIN2 to control endothelial cell proliferation and junctional integrity.
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    ncbi.nlm.nih.gov/pmc/articles/PMC11187247/
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    EYA protein complex is required for Wntless retrograde trafficking from endosomes to Golgi
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    sciencedirect.com/science/article/pii/S1534580724003393
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    Neuronal activity-driven O-GlcNAcylation promotes mitochondrial plasticity
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    sciencedirect.com/science/article/pii/S1534580724003253
  42. May 2024
  43. link.springer.com link.springer.com
    Prolactin is an Endogenous Antioxidant Factor in Astrocytes That Limits Oxidative Stress-Induced Astrocytic Cell Death via the STAT3/NRF2 Signaling Pathway
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    SARS-CoV-2 infection exacerbates the cellular pathology of Parkinson’s disease in human dopaminergic neurons and a mouse model
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  45. www.biorxiv.org www.biorxiv.org
    Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model
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  46. www.biorxiv.org www.biorxiv.org
    ProSAAS is Preferentially Secreted from Neurons During Homeostatic Scaling and Reduces Amyloid Plaque Size in the 5xFAD Mouse Hippocampus
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  47. Apr 2024
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    New Loss-of-Function Mutations in PCSK9 Reduce Plasma LDL Cholesterol
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    New Loss-of-Function Mutations in PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Reduce Plasma LDL (Low-Density Lipoprotein) Cholesterol
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  88. Oct 2023
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    ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct
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  90. Sep 2023
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fluid shear stress-modulated chromatin accessibility reveals the mechano-dependency of endothelial SMAD1/5-mediated gene transcription
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    Mechanism and evolutionary origins of alanine-tail C-degron recognition by E3 ligases Pirh2 and CRL2-KLHDC10
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  94. Aug 2023
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    The apoptotic, inflammatory, and fibrinolytic actions of vasoinhibin are in a motif different from its antiangiogenic HGR motif
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    NLRP11 is a pattern recognition receptor for bacterial lipopolysaccharide in the cytosol of human macrophages
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    The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr
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    Overexpression of NT-3 in the hippocampus suppresses the early phase of the adult neurogenic process
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    Senescent cells form nuclear foci that contain the 26S proteasome
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  100. Jul 2023
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    The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina
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  105. Jun 2023
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    The intracellular C-terminal domain of mGluR6 contains ER retention motifs
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    Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response
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    Centromere/kinetochore is assembled through CENP-C oligomerization
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    Endonuclease VIII-like 1 deficiency potentiates nigrostriatal dopaminergic neuron degeneration in a male mouse model of Parkinson's disease
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  112. May 2023
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    EWSR1 maintains centromere identity
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    Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex
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    Venlafaxine antagonizes the noradrenaline-promoted colon cancer progression by inhibiting the norepinephrine transporter
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    Plasma membrane preassociation drives β-arrestin coupling to receptors and activation
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    Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells
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  118. Apr 2023
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    RNA Pol II preferentially regulates ribosomal protein expression by trapping disassociated subunits
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    Fanconi anemia-associated chromosomal radial formation is dependent on POLθ-mediated alternative end joining
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    Identifying signatures of EV secretion in metastatic breast cancer through functional single-cell profiling
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    INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model
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    In-depth molecular profiling of an intronic GNAO1 mutant as the basis for personalized high-throughput drug screening
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  126. Mar 2023
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    FSBP suppresses tumor cell migration by inhibiting the JNK pathway
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    Selective dysfunction of fast-spiking inhibitory interneurons and disruption of perineuronal nets in a tauopathy mouse model
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    The ion channel CALHM6 controls bacterial infection-induced cellular cross-talk at the immunological synapse
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    H2-induced transient upregulation of phospholipids with suppression of energy metabolism
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    COP I and II dependent trafficking controls ER-associated degradation in mammalian cells
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    Concomitant inhibition of PPARγ and mTORC1 induces the differentiation of human monocytes into highly immunogenic dendritic cells
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  133. Feb 2023
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  135. Jan 2023
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    SARS-CoV-2 variants induce distinct disease and impact in the bone marrow and thymus of mice
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    Structurally distinct PARP7 inhibitors provide new insights into the function of PARP7 in regulating nucleic acid-sensing and IFN-β signaling
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    Galactosidase-catalyzed fluorescence amplification method (GAFAM): sensitive fluorescent immunohistochemistry using novel fluorogenic β-galactosidase substrates and its application in multiplex immunostaining
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    Granulosa Cell Dysfunction Is Associated with Diminished Ovarian Response in FMR1 Premutation Carriers
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    Table 2 | Autophagy-Mediated Inflammatory Cytokine Secretion in Sporadic ALS Patient iPSC-Derived Astrocytes
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    The Mettl3 epitranscriptomic writer amplifies p53 stress responses
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    The GADD45G/p38 MAPK/CDC25B signaling pathway enhances neurite outgrowth by promoting microtubule polymerization
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    Comparative distribution of Arcadlin/Protocadherin-8 mRNA in the intact and ischemic brains of adult mice
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  180. Mar 2022
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    Human Placental Tissue Contains a Placental Lactogen Derived Vasoinhibin
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    Mutant CHCHD10 causes an extensive metabolic rewiring that precedes OXPHOS dysfunction in a murine model of mitochondrial cardiomyopathy
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    RIF1 acts in DNA repair through phosphopeptide recognition of 53BP1
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    Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy
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    Alzheimer’s disease and cerebrovascular pathology alter brain endothelial inward rectifier potassium (KIR2.1) channels
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    An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function
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    Competition between type I activin and BMP receptors for binding to ACVR2A regulates signaling to distinct Smad pathways
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    Dual Sensing of Physiologic pH and Calcium by EFCAB9 Regulates Sperm Motility
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  190. Jan 2022
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    Histone Acetylation Defects in Brain Precursor Cells: A Potential Pathogenic Mechanism Causing Proliferation and Differentiation Dysfunctions in Mitochondrial Aspartate-Glutamate Carrier Isoform 1 Deficiency
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    C2cd6-encoded CatSperτ targets sperm calcium channel to Ca2+ signaling domains in the flagellar membrane
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  196. Dec 2021
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    Ocimum basilicum but not Ocimum gratissimum present cytotoxic effects on human breast cancer cell line MCF-7, inducing apoptosis and triggering mTOR/Akt/p70S6K pathway
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    Disrupted expression of mitochondrial NCLX sensitizes neuroglial networks to excitotoxic stimuli and renders synaptic activity toxic
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    Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity
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    Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson’s disease
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    Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction
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  209. Oct 2021
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    Munc13-1 is a Ca2+-phospholipid-dependent vesicle priming hub that shapes synaptic short-term plasticity and enables sustained neurotransmission
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    ABL allosteric inhibitors synergize with statins to enhance apoptosis of metastatic lung cancer cells
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    Cell geometry, signal dampening, and a bimodal transcriptional response underlie the spatial precision of an ERK-mediated embryonic induction
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    Cholecystokinin 1 receptor activation restores normal mTORC1 signaling and is protective to Purkinje cells of SCA mice
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    Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway
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    Secreted retrovirus-like GAG-domain-containing protein PEG10 is regulated by UBE3A and is involved in Angelman syndrome pathophysiology
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    Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed
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    Spatially Restricted Regulation of Spätzle/Toll Signaling during Cell Competition
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    1. scibot 06 Aug 2021
      RRID:AB_2307391

      DOI: 10.1016/j.immuni.2018.10.008

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    FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue
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    1. scibot 05 Aug 2021
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      DOI: 10.1016/j.celrep.2021.109481

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    ZBTB32 performs crosstalk with the glucocorticoid receptor and is crucial in glucocorticoid responses to starvation
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    1. scibot 05 Aug 2021
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      DOI: 10.1016/j.isci.2021.102790

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    ncbi.nlm.nih.gov/pmc/articles/PMC8324811/