433 Matching Annotations
  1. Last 7 days
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    Semaphorin3C identified as mediator of neuroinflammation and microglia polarization after spinal cord injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC11025009/
  3. Apr 2024
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    Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy
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    sciencedirect.com/science/article/pii/S0006295224001813
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    SRRM2 phase separation drives assembly of nuclear speckle subcompartments
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    sciencedirect.com/science/article/pii/S2211124724001554
  6. Mar 2024
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    The RNA binding proteins LARP4A and LARP4B promote sarcoma and carcinoma growth and metastasis
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    Endocytic activation and exosomal secretion of matriptase stimulate the second wave of EGF signaling to promote skin and breast cancer invasion
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    sciencedirect.com/science/article/pii/S2211124724003309
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    ATF4-SLC7A11-GSH axis mediates the acquisition of immunosuppressive properties by activated CD4+ T cells in low arginine condition
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    PRRC2B modulates oligodendrocyte progenitor cell development and myelination by stabilizing Sox2 mRNA
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    sciencedirect.com/science/article/pii/S2211124724002584
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    A unique chaperoning mechanism in class A JDPs recognizes and stabilizes mutant p53
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    sciencedirect.com/science/article/pii/S1097276524001370
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    Pneumococcal sialidase promotes bacterial survival by fine-tuning of pneumolysin-mediated membrane disruption
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    Securin acetylation prevents precocious separase activation and premature sister chromatid separation
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    Rim aperture of yeast autophagic membranes balances cargo inclusion with vesicle maturation
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    Uncovering the BIN1-SH3 interactome underpinning centronuclear myopathy
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      DOI: 10.7554/eLife.95397.1

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    HERC5-catalyzed ISGylation potentiates cGAS-mediated innate immunity
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  17. Feb 2024
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    The differential regulation of placenta trophoblast bisphosphoglycerate mutase in fetal growth restriction: preclinical study in mice and observational histological study of human placenta
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      DOI: 10.7554/eLife.82631

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    Glycolytic enzyme PFKFB3 regulates sphingosinae 1-phosphate receptor 1 in proangiogenic glomerular endothelial cells under diabetic condition
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    Dual roles of CCDC102A in governing centrosome duplication and cohesion
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    PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome
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  22. Jan 2024
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    Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints
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    In silico protein interaction screening uncovers DONSON’s role in replication initiation
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    Vinorelbine causes a neuropathic pain-like state in mice via STING and MNK1 signaling associated with type I interferon induction.
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    cwad087-html.html
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    Protocol to analyze the role of various metabolites in impacting global RNA 5-methylcytosine levels in cultured cells by dot blot
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      DOI: 10.1016/j.xpro.2023.102815

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  28. Dec 2023
  29. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation
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      DOI: 10.1002/advs.202305620

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    Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis
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    Pib2 is a cysteine sensor involved in TORC1 activation in Saccharomyces cerevisiae
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    Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts
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    Prothymosin α accelerates dengue virus-induced thrombocytopenia
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    Sequestration of translation initiation factors in p62 condensates
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    Smad4 sequestered in SFPQ condensates prevents TGF-β tumor-suppressive signaling
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    Proteomics analysis of the brain from a Gaucher disease mouse identifies pathological pathways including a possible role for transglutaminase 1
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    Identification of ZIP8-induced ferroptosis as a major type of cell death in monocytes under sepsis conditions
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    SYK ubiquitination by CBL E3 ligases restrains cross-presentation of dead cell-associated antigens by type 1 dendritic cells
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    Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability
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    sciencedirect.com/science/article/pii/S2211124723015152
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    Nutrient-regulated control of lysosome function by signaling lipid conversion
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    sciencedirect.com/science/article/pii/S0092867423010814
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    NAAG synthetase deficiency has only low influence on pathogenesis in a Canavan disease mouse model
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    onlinelibrary.wiley.com/doi/10.1002/jimd.12693
  42. Nov 2023
  43. www.sciencedirect.com www.sciencedirect.com
    MiR-337-3p improves metabolic-associated fatty liver disease through regulation of glycolipid metabolism
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    p120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP
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    Unbiased interrogation of functional lysine residues in human proteome
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    Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities
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    Biophysical properties of NaV1.5 channels from atrial-like and ventricular-like cardiomyocytes derived from human induced pluripotent stem cells
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    Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma
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  50. Oct 2023
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    PRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors
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    CPT1C is required for synaptic plasticity and oscillatory activity that supports motor, associative, and non-associative learning
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    The histone chaperone ANP32B regulates chromatin incorporation of the atypical human histone variant macroH2A
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    Identification of hyperoxidized PRDX3 as a ferroptosis marker reveals ferroptotic damage in chronic liver diseases
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    Antibody-directed extracellular proximity biotinylation reveals that Contactin-1 regulates axo-axonic innervation of axon initial segments
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    Heterozygous NF1 dermal fibroblasts modulate exosomal content to promote angiogenesis in a tissue-engineered skin model of neurofibromatosis type-1
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    Endothelial barrier dysfunction in systemic inflammation is mediated by soluble VE-cadherin interfering VE-PTP signaling
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    Gcn5- and Bre1-mediated Set2 degradation promotes chronological aging of Saccharomyces cerevisiae
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    Exposure to high-sugar diet induces transgenerational changes in sweet sensitivity and feeding behavior via H3K27me3 reprogramming
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    The heat shock protein Hsp27 controls mitochondrial function by modulating ceramide generation
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cardiac involvement in patient-specific induced pluripotent stem cells of myotonic dystrophy type 1: unveiling the impact of voltage-gated sodium channels
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    Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein
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    Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate
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  77. Jul 2023
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    PGAM5 is an MFN2 phosphatase that plays an essential role in the regulation of mitochondrial dynamics
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    Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer
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    SARS-CoV-2 ORF3c impairs mitochondrial respiratory metabolism, oxidative stress, and autophagic flux
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    Glutamine supplementation reverses manganese neurotoxicity by eliciting the mitochondrial unfolded protein response
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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression
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  89. 52.53.155.43 52.53.155.43
    The Journal of Physiology - 2023 - Iborra‐L zaro - CPT1C is required for synaptic plasticity and oscillatory activity that-html.html
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Co-translational binding of importins to nascent proteins
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    USP10 regulates ZEB1 ubiquitination and protein stability to inhibit ZEB1-mediated colorectal cancer metastasis
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    A Drosophila model of diabetic neuropathy reveals a role of proteasome activity in the glia
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    Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation
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    Deneddylating enzyme SENP8 regulates neuronal development
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    Alpha 7-nicotinic cholinergic regulation of pericyte-containing retinal capillaries
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  96. May 2023
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inflammatory and alternatively activated macrophages independently induce metaplasia but cooperatively drive pancreatic precancerous lesion growth
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  98. www.sciencedirect.com www.sciencedirect.com
    Heat shock factor 1 (HSF1) specifically potentiates c-MYC-mediated transcription independently of the canonical heat shock response
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    Depletion of CUL4B in macrophages ameliorates diabetic kidney disease via miR-194-5p/ITGA9 axis
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    Ubiquitin-independent proteasomal degradation driven by C-degron pathways
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    The mitochondrial intermembrane space protein mitofissin drives mitochondrial fission required for mitophagy
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    Kappa Opioid Receptor Antagonism Rescues Genetic Perturbation of Dopamine Homeostasis: Molecular, Physiological and Behavioral Consequences
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    Phosphorylation of neuroligin-2 by PKA regulates its cell surface abundance and synaptic stabilization
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  104. Apr 2023
  105. www.sciencedirect.com www.sciencedirect.com
    Thymidine kinase 1 drives hepatocellular carcinoma in enzyme-dependent and -independent manners
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    Antibody-directed extracellular proximity biotinylation reveals Contactin-1 regulates axo-axonic innervation of axon initial segments
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    Affinity-ranking BIN1 interactions and screening natural BIN1 variants that may cause neuromuscular disorders
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    STING activation in platelets aggravates septic thrombosis by enhancing platelet activation and granule secretion
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    Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS
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    Topological regulation of a transmembrane protein by luminal-to-cytosolic retrotranslocation of glycosylated sequence
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    Non-muscle myosin II drives critical steps of nematocyst morphogenesis
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    Two Hippo signaling modules orchestrate liver size and tumorigenesis
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    A spinal muscular atrophy modifier implicates the SMN protein in SNARE complex assembly at neuromuscular synapses
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    Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise
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    TRIM21-dependent target protein ubiquitination mediates cell-free Trim-Away
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    A concerted mechanism involving ACAT and SREBPs by which oxysterols deplete accessible cholesterol to restrict microbial infection
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    Mechanism of signal-anchor triage during early steps of membrane protein insertion
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    Clonal hematopoiesis driven by chromosome 1q/MDM4 trisomy defines a canonical route toward leukemia in Fanconi anemia
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    N-glycosylated intestinal protein BCF-1 shapes microbial colonization by binding bacteria via its fimbrial protein
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    Gasdermin D pore-forming activity is redox-sensitive
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    Immunohistochemical localisation of vasopressin/oxytocin-type, corazonin-type and luqin-type neuropeptide expression in the starfish Asterias rubens using antibodies to the C-terminal region of precursor proteins
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  126. aacrjournals.org aacrjournals.org
    Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells
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    Brain-derived neurotrophic factor (BDNF) induces antagonistic action to Nogo signaling by the upregulation of lateral olfactory tract usher substance (LOTUS) expression
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    RNA methylation influences TDP43 binding and disease pathogenesis in models of amyotrophic lateral sclerosis and frontotemporal dementia
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  143. Oct 2022
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    PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease
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    Fringe-positive Golgi outposts unite temporal Furin 2 convertase activity and spatial Delta signal to promote dendritic branch retraction
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    Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers
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    Cocaine preference and neuroadaptations are maintained by astrocytic NMDA receptors in the nucleus accumbens
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    The epilepsy-associated protein PCDH19 undergoes NMDA receptor-dependent proteolytic cleavage and regulates the expression of immediate-early genes
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    A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling
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    Age-Dependent Increase in Schmidt-Lanterman Incisures and a Cadm4-Associated Membrane Skeletal Complex in Fatty Acid 2-hydroxylase Deficient Mice: a Mouse Model of Spastic Paraplegia SPG35
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    CDYL1-dependent decrease in lysine crotonylation at DNA double-strand break sites functionally uncouples transcriptional silencing and repair
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    RBD trimer mRNA vaccine elicits broad and protective immune responses against SARS-CoV-2 variants
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    Lipid droplet dynamics regulate adult muscle stem cell fate
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    Clathrin-independent endocytic retrieval of SV proteins mediated by the clathrin adaptor AP-2 at mammalian central synapses
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  218. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Allele-specific endogenous tagging and quantitative analysis of β-catenin in colorectal cancer cells
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    1. scibot 15 Jan 2022
      RRID:AB_2313567

      DOI: 10.7554/eLife.64498

      Resource: (Jackson ImmunoResearch Labs Cat# 111-035-003, RRID:AB_2313567)

      Curator: @scibot

      SciCrunch record: RRID:AB_2313567

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      RRID:AB_2313567
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    ncbi.nlm.nih.gov/pmc/articles/PMC8752093/