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  1. Last 7 days
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    SARS-CoV-2 variant of concern fitness and adaptation in primary human airway epithelia
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    sciencedirect.com/science/article/pii/S2211124724004042
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    Olfactory bulb anomalies in KBG syndrome mouse model and patients
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    ncbi.nlm.nih.gov/pmc/articles/PMC11017579/
  4. Apr 2024
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    Generation of a human iPSC line from a Parkinson’s disease patient with a novel CHCHD2 mutation (R145Q)
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    Tamoxifen exerts direct and microglia-mediated effects preventing neuroinflammatory changes in the adult mouse hippocampal neurogenic niche
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    Regulation of muscle hypertrophy through granulin: Relayed communication among mesenchymal progenitors, macrophages, and satellite cells
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    Vangl-dependent mesenchymal thinning shapes the distal lung during murine sacculation
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    sciencedirect.com/science/article/pii/S1534580724001783
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    Extrasynaptic distribution of NMDA receptors in cochlear inner hair cell afferent signaling complex
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    sciencedirect.com/science/article/pii/S0891061824000309
  10. Mar 2024
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    Generation of KCNH2 heterozygous knockout induced pluripotent stem cell (iPSC) line (Long and Short QT Syndrome)
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    sciencedirect.com/science/article/pii/S1873506124000989
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    Nausea-induced suppression of feeding is mediated by central amygdala Dlk1-expressing neurons
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    sciencedirect.com/science/article/pii/S2211124724003188
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    Spatial patterning controls neuron numbers in the Drosophila visual system
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    Notch signaling and Bsh homeodomain activity are integrated to diversify Drosophila lamina neuron types
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    1. scibot 23 Mar 2024
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      DOI: 10.7554/eLife.90136

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    ncbi.nlm.nih.gov/pmc/articles/PMC10945509/
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    Homeodomain proteins hierarchically specify neuronal diversity and synaptic connectivity
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    Generation of a human induced pluripotent stem cell line harboring heteroplasmic m.3243A > G mutation in MT-TL1 gene
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    sciencedirect.com/science/article/pii/S1873506124000850
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    Infraorbital nerve injury triggers sex-specific neuroimmune responses in the peripheral trigeminal pathway and common pain behaviours
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    sciencedirect.com/science/article/pii/S0889159124003039
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    Development of activity-based anorexia requires PKC-δ neurons in two central extended amygdala nuclei
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    sciencedirect.com/science/article/pii/S2211124724002614
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    Immunohistochemical localization of P2Y12 purinoceptors in the rat carotid body
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    sciencedirect.com/science/article/pii/S1566070224000122
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    Generation of human induced pluripotent stem cell line from a patient with restrictive cardiomyopathy
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  21. Feb 2024
  22. 52.53.155.43 52.53.155.43
    Lesion of NPY Receptor-expressing Neurons in Perifornical Lateral Hypothalamus Attenuates Glucoprivic Feeding
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    A novel irreversible TEAD inhibitor, SWTX-143, blocks Hippo pathway transcriptional output and causes tumor regression in preclinical mesothelioma models
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    aacrjournals.org/mct/article/23/1/3/732154/A-Novel-Irreversible-TEAD-Inhibitor-SWTX-143
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    Neonatal brain injury unravels transcriptional and signaling changes underlying the reactivation of cortical progenitors
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    Redistribution of the glycocalyx exposes phagocytic determinants on apoptotic cells
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    Movement-related increases in subthalamic activity optimize locomotion
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      DOI: 10.1101/2023.12.07.570617

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    biorxiv.org/content/10.1101/2023.12.07.570617v2
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    Cost-effective strategies to knock down genes of interest in the retinas of adult zebrafish
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    Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity
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    Microglia maintain structural integrity during fetal brain morphogenesis
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    Ventral hippocampal cholecystokinin interneurons gate contextual reward memory
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  31. Jan 2024
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    Neonatal treatment with para-chlorophenylalanine (pCPA) induces adolescent hyperactivity associated with changes in the paraventricular nucleus Crh and Trh expressions
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    Lineage regulators TFAP2C and NR5A2 function as bipotency activators in totipotent embryos
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      DOI: 10.1038/s41594-023-01199-x

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    Sucrose overconsumption impairs AgRP neuron dynamics and promotes palatable food intake
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    Exercise-induced Musclin determines the fate of fibro-adipogenic progenitors to control muscle homeostasis
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      DOI: 10.1016/j.stem.2023.12.011

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    sciencedirect.com/science/article/pii/S1934590923004411
  36. www.jneurosci.org www.jneurosci.org
    Notch Signaling Plays a Dual Role in Regulating the Neuron-to-Oligodendrocyte Switch in the Developing Dorsal Forebrain
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      DOI: 10.1523/JNEUROSCI.0144-23.2023

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    jneurosci.org/content/43/41/6854
  37. 52.53.155.43 52.53.155.43
    Reproductive Profile of Neuronal Androgen Receptor Knockout Female Mice with Low Dose of DHT
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      DOI: 10.1210/endocr/bqad199

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    Hypothalamic CRF neurons facilitate brain reward function
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      DOI: 10.1016/j.cub.2023.12.046

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    sciencedirect.com/science/article/pii/S0960982223017463
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    Altered gene expression linked to germline dysfunction following exposure to DEET
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    sciencedirect.com/science/article/pii/S2589004223027761
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    The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling
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      DOI: 10.1016/j.devcel.2023.12.002

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    Embryonic temporal-spatial delineation of excitatory spinal V3 interneuron diversity
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  42. Dec 2023
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    Mesoaccumbal glutamate neurons drive reward via glutamate release but aversion via dopamine co-release
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    Reduced lysosomal density in neuronal dendrites mediates deficits in synaptic plasticity in Huntington’s disease
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    Astrocyte growth is driven by the Tre1/S1pr1 phospholipid-binding G protein-coupled receptor
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    Endosomal dysfunction contributes to cerebellar deficits in spinocerebellar ataxia type 6
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    Nfia is Critical for AII Amacrine Cell Production: Selective Bipolar Cell Dependencies and Diminished ERG
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    Sexually Dimorphic Effects of Histamine Degradation by Enteric Glial Histamine N-Methyltransferase (HNMT) on Visceral Hypersensitivity
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  49. Nov 2023
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    Extensive elimination of acinar cells during normal postnatal pancreas growth
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    Role of ST6GAL1 in Thyroid Cancers: Insights from Tissue Analysis and Genomic Datasets
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    Live birth of chimeric monkey with high contribution from embryonic stem cells
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    Generation of the induced pluripotent stem cell line ESi108-A from a familial atrial fibrillation patient
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    Integrative multi-omic profiling of adult mouse brain endothelial cells and potential implications in Alzheimer’s disease
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    Acid-base homeostasis orchestrated by NHE1 defines the pancreatic stellate cell phenotype in pancreatic cancer
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  56. Oct 2023
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    Generation of an Alagille syndrome (ALGS) patient-derived induced pluripotent stem cell line (TRNDi032-A) carrying a heterozygous mutation (p.Cys682Leufs*7) in the JAG1 gene
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  58. www.biorxiv.org www.biorxiv.org
    Notch signaling and Bsh homeodomain activity are integrated to diversify Drosophila lamina neuron types
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    Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses
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    The mesodermal and myogenic specification of hESCs depend on ZEB1 and are inhibited by ZEB2
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    Determinants of astrocytic pathology in stem cell models of primary tauopathies
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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct SAP102 and PSD-95 nano-organization defines multiple types of synaptic scaffold protein domains at single synapses
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    A Carbonic Anhydrase IX/SLC1A5 Axis Regulates Glutamine Metabolism Dependent Ferroptosis in Hypoxic Tumor Cells
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  65. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Three-dimensional architecture of the subepithelial corpuscular nerve ending in the rat epiglottis reconstructed by array tomography with scanning electron microscopy
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  66. Sep 2023
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    Protective effects of low-intensity pulsed ultrasound (LIPUS) against cerebral ischemic stroke in mice by promoting brain vascular remodeling via the inhibition of ROCK1/p-MLC2 signaling pathway
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    Cross-species analysis and comparison of the inner ear between chickens and mice
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  69. rupress.org rupress.org
    Maternal diet during early gestation influences postnatal taste activity–dependent pruning by microglia
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stromal cells-specific retinoic acid determines parturition timing at single-cell and spatial-temporal resolution
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    Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation
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  72. Aug 2023
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    Defining the identity and the niches of epithelial stem cells with highly pleiotropic multilineage potency in the human thymus
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    CD31 signaling promotes the detachment at the uropod of extravasating neutrophils allowing their migration to sites of inflammation
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    In vivo spontaneous activity and coital-evoked inhibition of mouse accessory olfactory bulb output neurons
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    Lateral preoptic area glutamate neurons relay nociceptive information to the ventral tegmental area
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    Stress-mediated dysregulation of the Rap1 small GTPase impairs hippocampal structure and function
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    Unique functional responses differentially map onto genetic subtypes of dopamine neurons
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    Single-cell analysis of the developing human ovary defines distinct insights into ovarian somatic and germline progenitors
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    Human microglia maturation is underpinned by specific gene regulatory networks
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    A neural circuit for male sexual behavior and reward
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  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuropeptide Y-expressing dorsal horn inhibitory interneurons gate spinal pain and itch signalling
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  83. Jul 2023
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy
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    Generation of gene corrected human isogenic iPSC lines (IDVi003-A_CR13, IDVi003-A_CR21, IDVi003-A_CR24) from an inherited retinal dystrophy patient-derived IPSC line ITM2B-5286-3 (IDVi003-A) carrying the ITM2B c.782A > C variant using CRISPR/Cas9
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    Contact sites between endoplasmic reticulum sheets and mitochondria regulate mitochondrial DNA replication and segregation
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    Paracingulin recruits CAMSAP3 to tight junctions and regulates microtubule and polarized epithelial organization
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  88. Jun 2023
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dysregulation of Metabolism and Proteostasis in Skeletal Muscle of a Presymptomatic Pompe Mouse Model
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    Uterine-specific Ezh2 deletion enhances stromal cell senescence and impairs placentation, resulting in pregnancy loss
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    Astrocytic α4-containing nAChR signaling in the hippocampus governs the formation of temporal association memory
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    Repurposing of the multiciliation gene regulatory network in fate specification of Cajal-Retzius neurons
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    Generation of an induced pluripotent stem cell line, ZIPi021-A, from fibroblasts of a Prader-Willi syndrome patient with maternal uniparental disomy (mUPD)
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    Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration
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    Quantitative biochemical phenotypic heterogeneity of macrophages after myelin debris phagocytosis at a single cell level by synchrotron radiation fourier transform infrared microspectroscopy
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  98. May 2023
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    Immunohistochemical analysis of glutamatergic and serotonergic signaling pathways in chemosensory cell clusters in the pharynx and larynx of rats
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    DRD1 signaling modulates TrkB turnover and BDNF sensitivity in direct pathway striatal medium spiny neurons
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    Post-weaning social isolation in male mice leads to abnormal aggression and disrupted network organization in the prefrontal cortex: Contribution of parvalbumin interneurons with or without perineuronal nets
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    Chemical-induced epigenome resetting for regeneration program activation in human cells
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    NS5806 reduces carrageenan-evoked inflammation by suppressing extracellular signal-regulated kinase activation in primary sensory neurons and immune cells
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    Single-cell transcriptomics of human-skin-equivalent organoids
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    A conditional strategy for cell-type-specific labeling of endogenous excitatory synapses in Drosophila
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    Vitamin K-dependent carboxylation regulates Ca2+ flux and adaptation to metabolic stress in β cells
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    An in vivo neuroimmune organoid model to study human microglia phenotypes
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  108. journals.lww.com journals.lww.com
    Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research
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    Diversity within olfactory sensory derivatives revealed by the contribution of Dbx1 lineages
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  110. Apr 2023
  111. www.sciencedirect.com www.sciencedirect.com
    Stress granule formation inhibits stress-induced apoptosis by selectively sequestering executioner caspases
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    A tissue injury sensing and repair pathway distinct from host pathogen defense
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    Axonal mRNA binding of hnRNP A/B is crucial for axon targeting and maturation of olfactory sensory neurons
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    Axon targeting of Drosophila medulla projection neurons requires diffusible Netrin and is coordinated with neuroblast temporal patterning
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    Notch-dependent binary fate choice regulates the Netrin pathway to control axon guidance of Drosophila visual projection neurons
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    Inflammatory signals from fatty bone marrow support DNMT3A driven clonal hematopoiesis
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    Plasticity in ventral pallidal cholinergic neuron-derived circuits contributes to comorbid chronic pain-like and depression-like behaviour in male mice
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    PPRX-1701, a nanoparticle formulation of 6′-bromoindirubin acetoxime, improves delivery and shows efficacy in preclinical GBM models
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    Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes
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    Cynomolgus monkey embryo model captures gastrulation and early pregnancy
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    SLFN5-mediated chromatin dynamics sculpt higher-order DNA repair topology
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    FGF21/FGFR1-β-KL cascade in cardiomyocytes modulates angiogenesis and inflammation under metabolic stress
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    Generation of two human NRF2 knockout iPSC clones using CRISPR/Cas9 editing
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  124. Mar 2023
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    Pain related neuronal ensembles in the primary somatosensory cortex contribute to hyperalgesia and anxiety
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    Highly efficient and rapid generation of human pluripotent stem cells by chemical reprogramming
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    Vascular and perivascular cell profiling reveals the molecular and cellular bases of blood-brain barrier heterogeneity
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    Salmonella infection induces the reorganization of follicular dendritic cell networks concomitant with the failure to generate germinal centers
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    Endothelial and Leptin Receptor+ cells promote the maintenance of stem cells and hematopoiesis in early postnatal murine bone marrow
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    Adult hippocampal neurogenesis and social behavioural deficits in the R451C Neuroligin3 mouse model of autism are reverted by the antidepressant Fluoxetine
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    Disturbed rhythmicity of intestinal hydrogen peroxide alters gut microbial oscillations in BMAL1-deficient monkeys
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    Differential remodeling of subthalamic projections to basal ganglia output nuclei and locomotor deficits in 6-OHDA-induced hemiparkinsonian mice
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    Stimulator of interferon genes (STING) expression in the enteric nervous system and contributions of glial STING in disease
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    Spinal VGLUT3 lineage neurons drive visceral mechanical allodynia but not sensitized visceromotor reflexes
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    Meiotic DNA exchanges in C. elegans are promoted by proximity to the synaptonemal complex
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    Microbiota-dependent and -independent postnatal development of salivary immunity
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    In vivo optogenetic inhibition of striatal parvalbumin-reactive interneurons induced genotype-specific changes in neuronal activity without dystonic signs in male DYT1 knock-in mice
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    Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer’s disease
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    Embryogenic stem cell-derived intestinal crypt fission directs de novo crypt genesis
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    Astrocyte heterogeneity within white matter tracts and a unique subpopulation of optic nerve head astrocytes
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    Dentate gyrus astrocytes exhibit layer-specific molecular, morphological and physiological features
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    Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies
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    CyclinD2-mediated regulation of neurogenic output from the retinal ciliary margin is perturbed in albinism
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    Protocol to image and quantify nucleocytoplasmic transport in cultured cells using fluorescent in situ hybridization and a dual reporter system
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    Alpha cell TXNIP deletion improves diabetes-associated hyperglycemia and hyperglucagonemia
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    Embryonic Deletion of TXNIP in GABAergic Neurons Enhanced Oxidative Stress in PV+ Interneurons in Primary Somatosensory Cortex of Aging Mice: Relevance to Schizophrenia
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    De novo establishment of circuit modules restores locomotion after spinal cord injury in adult zebrafish
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    Different priming states of synaptic vesicles underlie distinct release probabilities at hippocampal excitatory synapses
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    Somatotopy of mouse spinothalamic innervation and the localisation of a noxious stimulus requires DCC expression by Phox2a neurons
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    In situ cell-type-specific cell-surface proteomic profiling in mice
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    Efficient and reversible Cas13d-mediated knockdown with an all-in-one lentivirus-vector
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    Endothelial caveolin-1 regulates cerebral thrombo-inflammation in acute ischemia/reperfusion injury
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    SMN controls neuromuscular junction integrity through U7 snRNP
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    Generation of two TMEM16A knockout iPSC clones each from a healthy human iPSC line, from a Cystic Fibrosis patient specific line with p.Phe508del mutation and from the gene corrected iPSC line
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    Immunohistochemical localization of vesicular nucleotide transporter in small intensely fluorescent (SIF) cells of the rat superior cervical ganglion
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    Generation of an induced pluripotent stem cell lines HMSCASTi002-A from peripheral blood mononuclear cells of a 38-year-old healthy female individual
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    Molecular characteristics and laminar distribution of prefrontal neurons projecting to the mesolimbic system
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    Table 2 | Autophagy-Mediated Inflammatory Cytokine Secretion in Sporadic ALS Patient iPSC-Derived Astrocytes
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    Autophagy-Mediated Inflammatory Cytokine Secretion in Sporadic ALS Patient iPSC-Derived Astrocytes
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  177. Aug 2022
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    Dscam1 Has Diverse Neuron Type-Specific Functions in the Developing Drosophila CNS
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    Analysis of the distribution of vagal afferent projections from different peripheral organs to the nucleus of the solitary tract in rats
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    Serotonin Receptor 5-HT2A Regulates TrkB Receptor Function in Heteroreceptor Complexes
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    Temporal control of PDGFRα regulates the fibroblast-to-myofibroblast transition in wound healing
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    Single-cell transcriptome analysis of regenerating RGCs reveals potent glaucoma neural repair genes
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    Generation of TSC1 Knockout induced pluripotent stem cell (iPSC) line
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  184. Jul 2022
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    Anesthetic loss of consciousness induced by chemogenetic excitation of mesopontine effector neurons.
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  186. journals.lww.com journals.lww.com
    Nicotinic acetylcholine signaling is required for motor... : Neural Regeneration Research
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    Intersectional mapping of multi-transmitter neurons and other cell types in the brain
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  188. Jun 2022
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    SARS-CoV-2 infects an in vitro model of the human developing pancreas through endocytosis
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    Generation of four induced pluripotent stem cell lines from a family harboring a single nucleotide variant in SCN5A
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    Fast and high-fidelity in situ 3D imaging protocol for stem cells and niche components for mouse organs and tissues
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  192. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Structural arrangement of auditory brainstem nuclei in the bats Phyllostomus discolor and Carollia perspicillata
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    Neural activation associated with outgroup helping in adolescent rats
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    Cholinergic interneurons mediate cocaine extinction in male mice through plasticity across medium spiny neuron subtypes
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    γ-secretase promotes Drosophila postsynaptic development through the cleavage of a Wnt receptor
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  196. May 2022
  197. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    5-HT7 receptors expressed in the mouse parafacial region are not required for respiratory chemosensitivity
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    Non-canonical function of AGO2 augments T-cell receptor signaling in T-cell prolymphocytic leukemiaNovel non-canonical function of AGO2 in T-PLL
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    Choice-selective sequences dominate in cortical relative to thalamic inputs to NAc to support reinforcement learning
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    Cranial irradiation impairs intrinsic excitability and synaptic plasticity of hippocampal CA1 pyramidal neurons with implications for cognitive function
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  201. Apr 2022
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    Differential activation of pain circuitry neuron populations in a mouse model of spinal cord injury induced neuropathic pain
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  203. www.embopress.org www.embopress.org
    Astrogenesis in the murine dentate gyrus is a life-long and dynamic process
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    Treg tissue stability depends on lymphotoxin beta-receptor- and adenosine-receptor-driven lymphatic endothelial cell responses
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    Dorsal clock networks drive temperature preference rhythms in Drosophila
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    Dysregulation of the basal ganglia indirect pathway in early symptomatic Q175 Huntington’s disease mice
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    Quantitative super-resolution microscopy reveals promoting mitochondrial interconnectivity protects against AKI
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  208. Mar 2022
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    The TFIIH complex is required to establish and maintain mitotic chromosome structure
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    Positive feedback regulation of microglial glucose metabolism by histone H4 lysine 12 lactylation in Alzheimer’s disease
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    Midbrain projection to the basolateral amygdala encodes anxiety-like but not depression-like behaviors
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  212. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PBN-PVT projections modulate negative affective states in mice
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    Motoneuronal inflammasome activation triggers excessive neuroinflammation and impedes regeneration after sciatic nerve injury
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    Generation of the induced pluripotent stem cell line UKWNLi005-A derived from a patient with the GLA mutation c.376A>G of unknown pathogenicity in Fabry disease
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    Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease and dementia with Lewy bodies
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    link.springer.com/article/10.1186/s40478-022-01342-7
  216. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A cell-based system combined with flow cytometry to evaluate antibody responses against SARS-CoV-2 transmembrane proteins in patients with COVID-19
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    1. scibot 17 Mar 2022
      RRID:AB_2313584

      DOI: 10.1016/j.xpro.2022.101229

      Resource: (Jackson ImmunoResearch Labs Cat# 711-545-152, RRID:AB_2313584)

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    ncbi.nlm.nih.gov/pmc/articles/PMC8860709/
  217. www.sciencedirect.com www.sciencedirect.com
    P2X7-dependent constitutive Interleukin-1β release from pyramidal neurons of the normal mouse hippocampus: Evidence for a role in maintenance of the innate seizure threshold
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    1. scibot 13 Mar 2022
      RRID:AB_2313584

      DOI: 10.1016/j.nbd.2022.105689

      Resource: (Jackson ImmunoResearch Labs Cat# 711-545-152, RRID:AB_2313584)

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    sciencedirect.com/science/article/pii/S0969996122000808
  218. www.sciencedirect.com www.sciencedirect.com
    Generation of highly pure motor neurons from human induced pluripotent stem cells
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    1. scibot 11 Mar 2022
      RRID:AB_2313584

      DOI: 10.1016/j.xpro.2022.101223

      Resource: (Jackson ImmunoResearch Labs Cat# 711-545-152, RRID:AB_2313584)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S2666166722001034