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Mask protein keeps NF-κB precursor inactive by inducing a closed conformation and isolating it in biomolecular condensates

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1. scibot 06 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116225
  
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sciencedirect.com/science/article/pii/S2211124725009969
Aug 2025
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Plasma extracellular vesicle surface-located GAS6/PROS1 and CD39/CD73 attenuate inflammation

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  DOI: 10.1016/j.celrep.2025.116096
  
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sciencedirect.com/science/article/pii/S2211124725008678
Jul 2025
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The Hippo pathway kinase MST1 mediates a feedback loop to maintain NLRP3 inflammasome homeostasis

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1. scibot 29 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116076
  
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Endolysosomal damage surveillance enables rapid inflammasome sensing of pathogens

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1. scibot 16 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116002
  
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May 2025
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Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk-stimulated mouse MA-10 Leydig cells

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1. scibot 20 May 2025
  
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  DOI: 10.1111/andr.70051
  
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onlinelibrary.wiley.com/doi/10.1111/andr.70051
Apr 2025
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Type I interferons induce guanylate-binding proteins and lysosomal defense in hepatocytes to control malaria

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  DOI: 10.1016/j.chom.2025.03.008
  
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sciencedirect.com/science/article/pii/S1931312825000915
Mar 2025
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GEF-H1 drives breast cancer cells to tumor progression

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1. scibot 28 Mar 2025
  
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  DOI: 10.1016/j.bbadis.2025.167816
  
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sciencedirect.com/science/article/pii/S0925443925001619
Dec 2024
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Durable lymphocyte subset elimination upon a single dose of AAV-delivered depletion antibody dissects immune control of chronic viral infection

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1. scibot 24 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.021
  
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Molecular details and phospho-regulation of the CENP-T-Mis12 complex interaction during mitosis in DT40 cells

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1. scibot 13 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111295
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11612794/
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CRL3ARMC5 ubiquitin ligase and Integrator phosphatase form parallel mechanisms to control early stages of RNA Pol II transcription

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1. scibot 12 Dec 2024
  
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  DOI: 10.1016/j.molcel.2024.11.024
  
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sciencedirect.com/science/article/pii/S1097276524009493
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Microvilli control the morphogenesis of the tectorial membrane extracellular matrix

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1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.devcel.2024.11.011
  
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sciencedirect.com/science/article/pii/S1534580724006932
Nov 2024
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A shorter splicing isoform antagonizes ZBP1 to modulate cell death and inflammatory responses

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1. scibot 08 Nov 2024
  
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  DOI: 10.1038/s44318-024-00238-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11535224/
Oct 2024
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The TMEM132B-GABAA receptor complex controls alcohol actions in the brain

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1. scibot 02 Oct 2024
  
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  AB_2338128
  
  DOI: 10.1016/j.cell.2024.09.006
  
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sciencedirect.com/science/article/pii/S0092867424010249
Sep 2024
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Nuclear actin is a critical regulator of Drosophila female germline stem cell maintenance

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1. scibot 18 Sep 2024
  
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  DOI: 10.1101/2024.08.27.609996
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11383290/
Aug 2024
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Aerobic glycolysis but not GLS1-dependent glutamine metabolism is critical for anti-tumor immunity and response to checkpoint inhibition

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1. scibot 22 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114632
  
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sciencedirect.com/science/article/pii/S2211124724009823
May 2024
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A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death

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1. scibot 24 May 2024
  
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  DOI: 10.1016/j.immuni.2024.04.025
  
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Glial fibrillary acidic protein is pathologically modified in Alexander disease

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1. scibot 23 May 2024
  
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  AB_2338128
  
  DOI: 10.1016/j.jbc.2024.107402
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11259701/
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The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation

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1. scibot 14 May 2024
  
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  DOI: 10.1016/j.immuni.2024.04.016
  
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Unprocessed Genomic Uracil as a Source of DNA Replication Stress in Cancer Cells

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1. scibot 10 May 2024
  
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  DOI: 10.1101/2024.02.05.578390
  
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52.53.155.43/d52a41e1a3d17093378781ca7887483638d670e8/2024.02.05.578390.full-html.html
Apr 2024
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Unprocessed genomic uracil as a source of DNA replication stress in cancer cells

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  DOI: 10.1016/j.molcel.2024.04.004
  
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Adipocyte-Released Adipomes in Chagas Cardiomyopathy: Impact on Cardiac Metabolic and Immune Regulation

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1. scibot 28 Apr 2024
  
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  DOI: 10.1016/j.isci.2024.109672
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11039351/
Feb 2024
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Kin17 regulates proper cortical localization of Miranda in Drosophila neuroblasts by regulating Flfl expression

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1. scibot 23 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113823
  
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sciencedirect.com/science/article/pii/S2211124724001517
Jan 2024
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Rapamycin-sensitive mechanisms confine the growth of fission yeast below the temperatures detrimental to cell physiology

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1. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.isci.2023.108777
  
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Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells

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1. scibot 04 Jan 2024
  
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  DOI: 10.1016/j.devcel.2023.07.025
  
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  DOI: 10.1016/j.devcel.2023.07.025
  
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sciencedirect.com/science/article/pii/S1534580723003945
Sep 2023
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Oligodendrocyte precursor cells stop sensory axons regenerating into the spinal cord

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  DOI: 10.1016/j.celrep.2023.113068
  
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Jun 2023
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Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression

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1. scibot 17 Jun 2023
  
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  DOI: 10.1158/0008-5472.CAN-22-3848
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10267679/
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The Cdc48 N-terminal domain has a molecular switch that mediates the Npl4-Ufd1-Cdc48 complex formation

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1. scibot 16 Jun 2023
  
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  DOI: 10.1016/j.str.2023.05.014
  
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sciencedirect.com/science/article/pii/S0969212623001697
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Centromere/kinetochore is assembled through CENP-C oligomerization

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  DOI: 10.1016/j.molcel.2023.05.023
  
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sciencedirect.com/science/article/pii/S1097276523003799
Mar 2023
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Interaction between PI3K and the VDAC2 channel tethers Ras-PI3K-positive endosomes to mitochondria and promotes endosome maturation

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  DOI: 10.1016/j.celrep.2023.112229
  
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A spinal muscular atrophy modifier implicates the SMN protein in SNARE complex assembly at neuromuscular synapses

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  DOI: 10.1016/j.neuron.2023.02.004
  
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sciencedirect.com/science/article/pii/S089662732300082X
Feb 2023
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The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection

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1. scibot 23 Feb 2023
  
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  DOI: 10.1016/j.immuni.2023.01.029
  
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XCR1+ DCs are critical for T cell-mediated immunotherapy of chronic viral infections

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1. scibot 16 Feb 2023
  
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  DOI: 10.1016/j.celrep.2023.112123
  
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sciencedirect.com/science/article/pii/S2211124723001341
Aug 2022
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Ubiquitination of phosphatidylethanolamine in organellar membranes

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1. scibot 31 Aug 2022
  
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  DOI: 10.1016/j.molcel.2022.08.008
  
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sciencedirect.com/science/article/pii/S1097276522007614
Jun 2022
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MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression

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Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals

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Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway

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Antibody bivalency improves antiviral efficacy by inhibiting virion release independently of Fc gamma receptors

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ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder

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Defective brown adipose tissue thermogenesis and impaired glucose metabolism in mice lacking Letmd1

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Vectored antibody gene delivery restores host B and T cell control of persistent viral infection

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Fascin limits Myosin activity within Drosophila border cells to control substrate stiffness and promote migration

1
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ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis

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Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed

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SCAF4 and SCAF8, mRNA Anti-Terminator Proteins

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Untitled document

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Untitled document

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NMDA receptor blockade ameliorates abnormalities of spike firing of subthalamic nucleus neurons in a parkinsonian nonhuman primate

3
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Untitled document

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Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway

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IL-17 Inhibits Oligodendrocyte Progenitor Cell Proliferation and Differentiation by Increasing K+ Channel Kv1.3

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Transforming growth factor-β-regulated mTOR activity preserves cellular metabolism to maintain long-term T cell responses in chronic infection

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RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes

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Mitotic ER Exit Site Disassembly and Reassembly Are Regulated by the Phosphorylation Status of TANGO1

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IL-1-mediated sex differences in Kawasaki Disease vasculitis development and response to treatment

1
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Mapping of the contraction-induced phosphoproteome identifies TRIM28 as a significant regulator of skeletal muscle size and function

1
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Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses

1
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The Histone Methyltransferase DOT1L Is Essential for Humoral Immune Responses

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Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes

1
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Shigella flexneri Disruption of Cellular Tension Promotes Intercellular Spread

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Essentiality of CENP-A Depends on Its Binding Mode to HJURP

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isoTarget: A Genetic Method for Analyzing the Functional Diversity of Splicing Isoforms In Vivo

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Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses

1
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FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells

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The Requirement for US28 During Cytomegalovirus Latency Is Independent of US27 and US29 Gene Expression

1
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Nucleotide inhibition of the pancreatic ATP-sensitive K+ channel explored with patch-clamp fluorometry

1
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ncbi.nlm.nih.gov/pmc/articles/PMC7004565/
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Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

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1. scibot 15 Sep 2020
  
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  RRID:AB_2338128
  
  DOI: 10.1016/j.cell.2020.02.009
  
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sciencedirect.com/science/article/pii/S0092867420301537
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Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription

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1. scibot 15 Sep 2020
  
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  RRID:AB_2338128
  
  DOI: 10.1016/j.stem.2020.03.002
  
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sciencedirect.com/science/article/pii/S1934590920300941
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A Mutation in Hnrnph1 That Decreases Methamphetamine-Induced Reinforcement, Reward, and Dopamine Release and Increases Synaptosomal hnRNP H and Mitochondrial Proteins

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1. scibot 13 Sep 2020
  
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  RRID:AB_2338128
  
  DOI: 10.1523/JNEUROSCI.1808-19.2019
  
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jneurosci.org/content/40/1/107
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Expression of different L1 isoforms of Mastomys natalensis papillomavirus as mechanism to circumvent adaptive immunity

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  DOI: 10.7554/eLife.57626
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7402679/
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Landscape of Exhausted Virus-Specific CD8 T Cells in Chronic LCMV Infection

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1. scibot 10 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.108078
  
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sciencedirect.com/science/article/pii/S2211124720310639
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Niemann-Pick C1 Heterogeneity of Bat Cells Controls Filovirus Tropism

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1. scibot 10 Sep 2020
  
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  DOI: 10.1016/j.celrep.2019.12.042
  
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sciencedirect.com/science/article/pii/S2211124719316997
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Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition

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  DOI: 10.1016/j.celrep.2020.107783
  
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sciencedirect.com/science/article/pii/S2211124720307634
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Heat Shock Factor 1 Is a Direct Antagonist of AMP-Activated Protein Kinase

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.molcel.2019.08.021
  
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sciencedirect.com/science/article/pii/S1097276519306604
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Untitled document

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  DOI: 10.7554/eLife.39637
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6301793/
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Salt-Responsive Metabolite, β-Hydroxybutyrate, Attenuates Hypertension

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1. scibot 13 Jan 2020
  
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  RRID:AB_2338128
  
  DOI: 10.1016/j.celrep.2018.09.058
  
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Untitled document

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  DOI: 10.7554/eLife.41103
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6400584/
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Untitled document

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  DOI: 10.1016/j.cell.2019.04.038
  
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sciencedirect.com/science/article/pii/S009286741930457X
Nov 2018
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5-HT 2A receptor-dependent phosphorylation of mGlu 2 receptor at Serine 843 promotes mGlu 2 receptor-operated G i/o signaling

1
1. scibot 05 Nov 2018
  
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  112-035-003
  
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nature.com/articles/s41380-018-0069-6
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The Soluble Form of LOTUS inhibits Nogo Receptor-Mediated Signaling by Interfering with the Interaction Between Nogo Receptor Type 1 and p75 Neurotrophin Receptor

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1. scibot 05 Nov 2018
  
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jneurosci.org/content/38/10/2589
Nov 2017
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Interferon-γ-Driven iNOS: A Molecular Pathway to Terminal Shock in Arenavirus Hemorrhagic Fever

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1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S1931312817302913

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