94 Matching Annotations
  1. Apr 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rab7-dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis
    1
    1. scibot 11 Apr 2024
      RRID:AB_2339149

      DOI: 10.7554/eLife.89776

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    ncbi.nlm.nih.gov/pmc/articles/PMC11003743/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Galectin-1 mediates chronic STING activation in tumors to promote metastasis through MDSC recruitment
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    1. scibot 03 Apr 2024
      RRID:AB_2339149

      DOI: 10.1158/0008-5472.CAN-23-0046

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    ncbi.nlm.nih.gov/pmc/articles/PMC10592379/
  4. Mar 2024
  5. www.sciencedirect.com www.sciencedirect.com
    RPGR is a guanine nucleotide exchange factor for the small GTPase RAB37 required for retinal function via autophagy regulation
    1
    1. scibot 28 Mar 2024
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      DOI: 10.1016/j.celrep.2024.114010

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    sciencedirect.com/science/article/pii/S2211124724003383
  6. Feb 2024
  7. www.sciencedirect.com www.sciencedirect.com
    ABHD7-mediated depalmitoylation of lamin A promotes myoblast differentiation
    1
    1. scibot 09 Feb 2024
      AB_2339149

      DOI: 10.1016/j.celrep.2024.113720

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    sciencedirect.com/science/article/pii/S2211124724000482
  8. Jan 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In silico protein interaction screening uncovers DONSON’s role in replication initiation
    1
    1. scibot 24 Jan 2024
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      DOI: 10.1126/science.adi3448

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    ncbi.nlm.nih.gov/pmc/articles/PMC10801813/
  10. Dec 2023
  11. www.sciencedirect.com www.sciencedirect.com
    SYK ubiquitination by CBL E3 ligases restrains cross-presentation of dead cell-associated antigens by type 1 dendritic cells
    1
    1. scibot 02 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113506

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    sciencedirect.com/science/article/pii/S2211124723015188
  12. Sep 2023
  13. 52.53.155.43 52.53.155.43
    Adipocyte glucocorticoid receptor inhibits immune regulatory genes to maintain immune cell homeostasis in adipose tissue
    1
    1. scibot 30 Sep 2023
      RRID:AB_2339149

      DOI: 10.1210/endocr/bqad143

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    52.53.155.43/25cb166ca2846e48613c47bb2324d21f264fec8b/bqad143-html.html
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    Estradiol and 3β-diol protect female cortical astrocytes by regulating connexin 43 Gap Junctions
    1
    1. scibot 29 Sep 2023
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      DOI: 10.1016/j.mce.2023.112045

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    sciencedirect.com/science/article/pii/S030372072300196X
  15. Aug 2023
  16. www.science.org www.science.org
    In silico protein interaction screening uncovers DONSON’s role in replication initiation
    1
    1. scibot 29 Aug 2023
      RRID:AB_2339149

      DOI: 10.1126/science.adi3448

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    science.org/doi/10.1126/science.adi3448
  17. Jun 2023
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Detection of Arc/Arg3.1 oligomers in rat brain: constitutive and synaptic activity-evoked dimer expression in vivo
    1
    1. scibot 27 Jun 2023
      RRID:AB_2339149

      DOI: 10.3389/fnmol.2023.1142361

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    ncbi.nlm.nih.gov/pmc/articles/PMC10289200/
  19. www.sciencedirect.com www.sciencedirect.com
    Acetylation halts missense mutant p53 aggregation and rescues tumor suppression in non-small cell lung cancers
    1
    1. scibot 16 Jun 2023
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      DOI: 10.1016/j.isci.2023.107003

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    sciencedirect.com/science/article/pii/S2589004223010805
  20. dx.doi.org dx.doi.org
    Novel MKRN3 Missense Mutations Associated with Central Precocious Puberty Reveal Distinct Effects on Ubiquitination
    1
    1. scibot 10 Jun 2023
      RRID:AB_2339149

      DOI: 10.1210/clinem/dgad151

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    dx.doi.org/10.1210/clinem/dgad151
  21. dx.doi.org dx.doi.org
    (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers
    1
    1. scibot 10 Jun 2023
      RRID:AB_2339149

      DOI: 10.1158/2159-8290.CD-22-0825

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    dx.doi.org/10.1158/2159-8290.CD-22-0825
  22. May 2023
  23. www.sciencedirect.com www.sciencedirect.com
    ESCRT recruitment to SARS-CoV-2 spike induces virus-like particles that improve mRNA vaccines
    1
    1. scibot 06 May 2023
      RRID:AB_2339149

      DOI: 10.1016/j.cell.2023.04.024

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    sciencedirect.com/science/article/pii/S0092867423004208
  24. Apr 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Glioma epileptiform activity and progression are driven by IGSF3-mediated potassium dysregulation
    1
    1. scibot 27 Apr 2023
      RRID:AB_2339149

      DOI: 10.1016/j.neuron.2023.01.013

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    sciencedirect.com/science/article/pii/S0896627323000375
  26. Mar 2023
  27. www.embopress.org www.embopress.org
    Two Hippo signaling modules orchestrate liver size and tumorigenesis
    2
    1. scibot 16 Mar 2023
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      DOI: 10.15252/embj.2022112126

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      DOI: 10.15252/embj.2022112126

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    embopress.org/doi/10.15252/embj.2022112126
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CHD1 promotes sensitivity to Aurora kinase inhibitors by suppressing interaction of AURKA with its coactivator TPX2
    1
    1. scibot 05 Mar 2023
      RRID:AB_2339149

      DOI: 10.1158/0008-5472.CAN-22-0631

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    ncbi.nlm.nih.gov/pmc/articles/PMC9444962/
  29. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 03 Mar 2023
      RRID:AB_2339149

      DOI: 10.1111/bph.16035

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16035
  30. Feb 2023
  31. www.sciencedirect.com www.sciencedirect.com
    TRIM21-dependent target protein ubiquitination mediates cell-free Trim-Away
    2
    1. scibot 23 Feb 2023
      RRID:AB_2339149

      DOI: 10.1016/j.celrep.2023.112125

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    2. scibot 23 Feb 2023
      RRID:AB_2339149

      DOI: 10.1016/j.celrep.2023.112125

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    sciencedirect.com/science/article/pii/S2211124723001365
  32. Jan 2023
  33. 52.53.155.43 52.53.155.43
    SSRN-id4254517-html.html
    1
    1. scibot 14 Jan 2023
      AB_2339149

      DOI: 10.3389/fncel.2013.00159

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    52.53.155.43/2e4506235f9c936cffbdc170be9afd0cc4c958b9/SSRN-id4254517-html.html
  34. Nov 2022
  35. www.sciencedirect.com www.sciencedirect.com
    Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins
    1
    1. scibot 24 Nov 2022
      RRID:AB_2339149

      DOI: 10.1016/j.celrep.2022.111675

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    sciencedirect.com/science/article/pii/S2211124722015492
  36. www.sciencedirect.com www.sciencedirect.com
    Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis
    1
    1. scibot 18 Nov 2022
      RRID:AB_2339149

      DOI: 10.1016/j.molcel.2022.10.027

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    sciencedirect.com/science/article/pii/S1097276522010553
  37. Aug 2022
  38. www.sciencedirect.com www.sciencedirect.com
    Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers
    1
    1. scibot 31 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111296

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    sciencedirect.com/science/article/pii/S2211124722011160
  39. 52.53.155.43 52.53.155.43
    can-22-0631-html.html
    1
    1. scibot 27 Aug 2022
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      DOI: 10.1158/0008-5472.CAN-22-0631

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    52.53.155.43/eb3d97bd3689fdec423c36bb1ce8ba7443cda401/can-22-0631-html.html
  40. www.sciencedirect.com www.sciencedirect.com
    Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development
    1
    1. scibot 23 Aug 2022
      RRID:AB_2339149

      DOI: 10.1016/j.isci.2022.104905

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    sciencedirect.com/science/article/pii/S2589004222011774
  41. May 2022
  42. www.sciencedirect.com www.sciencedirect.com
    NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition
    1
    1. scibot 12 May 2022
      RRID:AB_2339149

      DOI: 10.1016/j.molcel.2022.04.015

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    sciencedirect.com/science/article/pii/S1097276522003264
  43. www.sciencedirect.com www.sciencedirect.com
    The Mettl3 epitranscriptomic writer amplifies p53 stress responses
    1
    1. scibot 05 May 2022
      RRID:AB_2339149

      DOI: 10.1016/j.molcel.2022.04.010

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    sciencedirect.com/science/article/pii/S1097276522003215
  44. Apr 2022
  45. www.sciencedirect.com www.sciencedirect.com
    WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy
    1
    1. scibot 20 Apr 2022
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      DOI: 10.1016/j.molcel.2022.03.027

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    sciencedirect.com/science/article/pii/S1097276522002659
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ACTL6a coordinates axonal caliber recognition and myelination in the peripheral nerve.
    1
    1. scibot 19 Apr 2022
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      DOI: 10.1016/j.isci.2022.104132

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    ncbi.nlm.nih.gov/pmc/articles/PMC9010646/
  47. www.sciencedirect.com www.sciencedirect.com
    Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure
    1
    1. scibot 07 Apr 2022
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      DOI: 10.1016/j.cmet.2022.03.005

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    sciencedirect.com/science/article/pii/S1550413122000936
  48. Mar 2022
  49. link.springer.com link.springer.com
    Development and Validation of Arc Nanobodies: New Tools for Probing Arc Dynamics and Function
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    1. scibot 22 Mar 2022
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      DOI: 10.1007/s11064-022-03573-5

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    link.springer.com/article/10.1007/s11064-022-03573-5
  50. www.sciencedirect.com www.sciencedirect.com
    Lipid flippase dysfunction as a therapeutic target for endosomal anomalies in Alzheimer’s disease
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    1. scibot 02 Mar 2022
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      DOI: 10.1016/j.isci.2022.103869

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    sciencedirect.com/science/article/pii/S2589004222001390
  51. Dec 2021
  52. www.sciencedirect.com www.sciencedirect.com
    Calpain-2 regulates hypoxia/HIF-induced plasticity toward amoeboid cancer cell migration and metastasis
    1
    1. scibot 09 Dec 2021
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      DOI: 10.1016/j.cub.2021.11.040

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    sciencedirect.com/science/article/pii/S0960982221015992
  53. Nov 2021
  54. www.sciencedirect.com www.sciencedirect.com
    Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1
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    1. scibot 12 Nov 2021
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      DOI: 10.1016/j.molcel.2021.10.015

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    sciencedirect.com/science/article/pii/S1097276521009072
  55. Oct 2021
  56. www.sciencedirect.com www.sciencedirect.com
    Cardiac proteomics reveals sex chromosome-dependent differences between males and females that arise prior to gonad formation
    1
    1. scibot 16 Oct 2021
      RRID:AB_2339149

      DOI: 10.1016/j.devcel.2021.09.022

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    sciencedirect.com/science/article/pii/S1534580721007668
  57. www.embopress.org www.embopress.org
    Promyelocytic leukemia protein targets MK2 to promote cytotoxicity
    1
    1. scibot 12 Oct 2021
      RRID:AB_2339149

      DOI: 10.15252/embr.202052254

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    embopress.org/doi/abs/10.15252/embr.202052254
  58. Sep 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Dynamic interplay of two molecular switches enabled by the MEK1/2-ERK1/2 and IL-6-STAT3 signaling axes controls epithelial cell migration in response to growth factors
    1
    1. scibot 04 Sep 2021
      211-032-171

      DOI: 10.1016/j.jbc.2021.101161

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    sciencedirect.com/science/article/pii/S0021925821009637
  60. Aug 2021
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer
    1
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  63. Jul 2021
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    Thyroid Hormone Receptor β Suppression of RUNX2 is Mediated by Brahma Related Gene 1 Dependent Chromatin Remodeling
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    ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer
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    Site-specific O-GlcNAcylation of Psme3 maintains mouse stem cell pluripotency by impairing P-body homeostasis
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  68. Jun 2021
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    STIM1 Mediates Calcium-dependent Epigenetic Reprogramming in Pancreatic Cancer
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  70. May 2021
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    Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging
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    A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation
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    TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate
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    SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy
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    Pimavanserin, a 5HT2A receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer’s disease
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    The tumor suppressor LATS2 reduces v‐Src‐induced membrane blebs in a kinase activity‐independent manner
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    Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit
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    Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma
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  88. Dec 2020
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    Slc26a6 is an apical membrane anion exchanger that drives HCO3−-dependent fluid secretion in murine pancreatic acinar cells
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    MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARγ-Dependent Gene Expression
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    An Essential and Cell-Cycle-Dependent ORC Dimerization Cycle Regulates Eukaryotic Chromosomal DNA Replication
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    FMRP Control of Ribosome Translocation Promotes Chromatin Modifications and Alternative Splicing of Neuronal Genes Linked to Autism
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    Site-Specific Photo-Crosslinking Proteomics Reveal Regulation of IFITM3 Trafficking and Turnover by VCP/p97 ATPase
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    Slc26a6 is an apical membrane anion exchanger that drives HCO3−-dependent fluid secretion in murine pancreatic acinar cells | American Journal of Physiology-Cell Physiology
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  102. Jan 2020
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    CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation
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    KAE1 Allelic Variants Affect TORC1 Activation and Fermentation Kinetics in Saccharomyces cerevisiae
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    TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer
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      DOI: 10.1016/j.stem.2019.02.017

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    FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer
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      DOI: 10.1016/j.celrep.2019.02.054

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  113. Nov 2018
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    WDR5 Stabilizes Actin Architecture to Promote Multiciliated Cell Formation
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    Hsp90 Mediates Membrane Deformation and Exosome Release
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    The THO Complex Coordinates Transcripts for Synapse Development and Dopamine Neuron Survival
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    Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures
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    DUB3 Promotes BET Inhibitor Resistance and Cancer Progression by Deubiquitinating BRD4
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    TALE factors use two distinct functional modes to control an essential zebrafish gene expression program
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    ER Lipid Defects in Neuropeptidergic Neurons Impair Sleep Patterns in Parkinson’s Disease
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    Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding
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    RAPGEF5 Regulates Nuclear Translocation of β-Catenin
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    MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma
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  126. Nov 2017
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    p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway
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    Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory “FADDosome” Complex upon TRAIL Stimulation
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