85 Matching Annotations
  1. Jul 2025
  2. www.biorxiv.org www.biorxiv.org
    Integrated genetic screening reveals FEN1 as a driver of stemness and temozolomide resistance in glioblastoma
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    biorxiv.org/content/10.1101/2025.06.18.660339v1
  3. May 2025
  4. www.sciencedirect.com www.sciencedirect.com
    Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target
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    sciencedirect.com/science/article/pii/S1535610825001734
  5. Mar 2025
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    CDK4 selective inhibition improves preclinical anti-tumor efficacy and safety
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    sciencedirect.com/science/article/pii/S1535610825000583
  7. Feb 2025
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    Spatiotemporal analysis of ratiometric biosensors in live multicellular spheroids using SPoRTS
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    sciencedirect.com/science/article/pii/S2667237525000232
  9. Jan 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Accelerated production of human epithelial organoids in a miniaturized spinning bioreactor
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    pmc.ncbi.nlm.nih.gov/articles/PMC11705766/
  11. Dec 2024
  12. www.cell.com www.cell.com
    Hyperreactive B cells instruct their elimination by T cells to curb autoinflammation and lymphomagenesis
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    cell.com/immunity/abstract/S1074-7613(24)00538-7
  13. Sep 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis
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    sciencedirect.com/science/article/pii/S1934590919301055
  15. Aug 2024
  16. www.nature.com www.nature.com
    Motor innervation directs the correct development of the mouse sympathetic nervous system
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    nature.com/articles/s41467-024-51290-0
  17. Jul 2024
  18. www.science.org www.science.org
    Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer
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    science.org/doi/10.1126/science.adh4567
  19. Jun 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRX4204 Induces Senescence and Cell Death in HER2-positive Breast Cancer and Synergizes with Anti-HER2 Therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11145169/
  21. May 2024
  22. www.sciencedirect.com www.sciencedirect.com
    A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1
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    sciencedirect.com/science/article/pii/S1550413124001359
  23. Apr 2024
  24. www.sciencedirect.com www.sciencedirect.com
    NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo
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    sciencedirect.com/science/article/pii/S1934590924000845
  25. Nov 2023
  26. www.sciencedirect.com www.sciencedirect.com
    p120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP
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    sciencedirect.com/science/article/pii/S2211124723014985
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    Extensive elimination of acinar cells during normal postnatal pancreas growth
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    sciencedirect.com/science/article/pii/S2211124723014699
  28. www.sciencedirect.com www.sciencedirect.com
    p57Kip2 acts as a transcriptional corepressor to regulate intestinal stem cell fate and proliferation
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    sciencedirect.com/science/article/pii/S2211124723006708
  29. www.sciencedirect.com www.sciencedirect.com
    Insulin receptor loss impairs mammary tumorigenesis in mice
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    sciencedirect.com/science/article/pii/S2211124723012639
  30. Oct 2023
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatiotemporal Regulation of De Novo and Salvage Purine Synthesis during Brain Development
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    ncbi.nlm.nih.gov/pmc/articles/PMC10566546/
  32. Sep 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Effects of butyl benzyl phthalate exposure during pregnancy and lactation on the post-involution mammary gland
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    sciencedirect.com/science/article/pii/S0890623823001442
  34. Aug 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Dual role of the adhesion G-protein coupled receptor ADRGE5/CD97 in glioblastoma invasion and proliferation
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    sciencedirect.com/science/article/pii/S0021925823021336
  36. Jul 2023
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATF6-mediated signaling contributes to PARP Inhibitor Resistance in Ovarian Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9812934/
  38. Jun 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Sublethal necroptosis signaling promotes inflammation and liver cancer
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    sciencedirect.com/science/article/pii/S1074761323002340
  40. aacrjournals.org aacrjournals.org
    Olig1/2-expressing intermediate lineage progenitors are predisposed to PTEN/p53-loss-induced gliomagenesis and harbor specific therapeutic vulnerabilities
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    aacrjournals.org/cancerres/article/83/6/890/718574/Olig1-2-Expressing-Intermediate-Lineage
  41. May 2023
  42. www.mdpi.com www.mdpi.com
    Hedgehog Signaling Pathway Orchestrates Human Lung Branching Morphogenesis
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    mdpi.com/1422-0067/23/9/5265/htm
  43. Apr 2023
  44. www.biorxiv.org www.biorxiv.org
    Combination CDC-like kinase inhibition (CLK)/Dual-specificity tyrosine-regulated kinase (DYRK) and taxane therapy in CTNNB1-mutated endometrial cancer
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    biorxiv.org/content/10.1101/2023.04.04.535570v1
  45. Local file Local file
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  46. Jan 2023
  47. www.sciencedirect.com www.sciencedirect.com
    GSNOR deficiency promotes tumor growth via FAK1 S-nitrosylation
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    sciencedirect.com/science/article/pii/S2211124723000086
  48. Dec 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Glycemic control releases regenerative potential of pancreatic beta cells blocked by severe hyperglycemia
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    sciencedirect.com/science/article/pii/S2211124722015972
  50. Nov 2022
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell-intrinsic differences between human airway epithelial cells from children and adults
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    ncbi.nlm.nih.gov/pmc/articles/PMC9664344/
  52. www.sciencedirect.com www.sciencedirect.com
    Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma
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    sciencedirect.com/science/article/pii/S1535610822005001
  53. Oct 2022
  54. www.liebertpub.com www.liebertpub.com
    Mild Traumatic Brain Injury/Concussion Initiates an Atypical Astrocyte Response Caused by Blood–Brain Barrier Dysfunction
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    liebertpub.com/doi/10.1089/neu.2021.0204
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Smooth muscle Acid-sensing ion channel 1a as a therapeutic target to reverse hypoxic pulmonary hypertension
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    ncbi.nlm.nih.gov/pmc/articles/PMC9581175/
  56. Jul 2022
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decoding the activated stem cell phenotype of the neonatally maturing pituitary
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    ncbi.nlm.nih.gov/pmc/articles/PMC9333987/
  58. link.springer.com link.springer.com
    Tbr1 Misexpression Alters Neuronal Development in the Cerebral Cortex
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    link.springer.com/article/10.1007/s12035-022-02936-x
  59. Jun 2022
  60. www.sciencedirect.com www.sciencedirect.com
    R-SPONDIN2+ mesenchymal cells form the bud tip progenitor niche during human lung development
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    sciencedirect.com/science/article/pii/S1534580722003677
  61. May 2022
  62. www.sciencedirect.com www.sciencedirect.com
    Therapeutic development for Canavan disease using patient iPSCs introduced with the wild-type ASPA gene
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    sciencedirect.com/science/article/pii/S2589004222006629
  63. academic.oup.com academic.oup.com
    Dietary supplementation with lysine (protein) stimulates mammary development in late-pregnant gilts
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    academic.oup.com/jas/article/100/5/skac051/6532658
  64. Apr 2022
  65. journals.physiology.org journals.physiology.org
    Hypoxia-inducible factor protects against acute kidney injury via the Wnt/β-catenin signaling pathway
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    journals.physiology.org/doi/full/10.1152/ajprenal.00023.2022
  66. aacrjournals.org aacrjournals.org
    Loss of Claudin-4 Reduces DNA Damage Repair and Increases Sensitivity to PARP Inhibitors
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    aacrjournals.org/mct/article/21/4/647/689566/Loss-of-Claudin-4-Reduces-DNA-Damage-Repair-and
  67. Mar 2022
  68. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    PTENα regulates endocytosis and modulates olfactory function
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.201900588RR
  69. www.sciencedirect.com www.sciencedirect.com
    Central dopaminergic control of cell proliferation in the colonic epithelium
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    sciencedirect.com/science/article/pii/S0168010222000736
  70. Feb 2022
  71. www.sciencedirect.com www.sciencedirect.com
    Suspension culture promotes serosal mesothelial development in human intestinal organoids
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    sciencedirect.com/science/article/pii/S2211124722001000
  72. www.sciencedirect.com www.sciencedirect.com
    Image-guided surgery with a new tumour-targeting probe improves the identification of positive margins
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    sciencedirect.com/science/article/pii/S2352396422000342
  73. Jan 2022
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Triple targeting of breast tumors driven by hormonal receptors and HER2
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    ncbi.nlm.nih.gov/pmc/articles/PMC8742793/
  75. Dec 2021
  76. www.sciencedirect.com www.sciencedirect.com
    NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis
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    sciencedirect.com/science/article/pii/S1550413121005398
  77. Oct 2021
  78. mct.aacrjournals.org mct.aacrjournals.org
    Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor–Resistant Melanoma
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    mct.aacrjournals.org/content/20/10/2049
  79. academic.oup.com academic.oup.com
    Uterine epithelial LIF receptors contribute to implantation chamber formation in blastocyst attachment
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    academic.oup.com/endo/article/162/11/bqab169/6353290
  80. Sep 2021
  81. www.sciencedirect.com www.sciencedirect.com
    A hydride transfer complex reprograms NAD metabolism and bypasses senescence
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    sciencedirect.com/science/article/pii/S109727652100695X
  82. www.sciencedirect.com www.sciencedirect.com
    Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging
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    sciencedirect.com/science/article/pii/S2211124721011360
  83. www.sciencedirect.com www.sciencedirect.com
    Genomic and functional characterization of a mucosal symbiont involved in early-stage colorectal cancer
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    sciencedirect.com/science/article/pii/S1931312821003899
  84. Aug 2021
  85. www.sciencedirect.com www.sciencedirect.com
    Functional diagnostics using fresh uncultured lung tumor cells to guide personalized treatments
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    sciencedirect.com/science/article/pii/S2666379121002275
  86. www.sciencedirect.com www.sciencedirect.com
    Geographic differences in gut microbiota composition impact susceptibility to enteric infection
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    sciencedirect.com/science/article/pii/S2211124721008743
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cyclophosphamide and the taste system: Effects of dose fractionation and amifostine on taste cell renewal
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    ncbi.nlm.nih.gov/pmc/articles/PMC6448888/
  88. europepmc.org europepmc.org
    Cellular mechanisms of cyclophosphamide-induced taste loss in mice.
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    europepmc.org/articles/PMC5614555/
  89. www.fasebj.org www.fasebj.org
    PTENα regulates endocytosis and modulates olfactory function
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    fasebj.org/doi/abs/10.1096/fj.201900588RR
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6220985/
  91. Jul 2021
  92. www.sciencedirect.com www.sciencedirect.com
    AXIN2+ Pericentral Hepatocytes Have Limited Contributions to Liver Homeostasis and Regeneration
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    sciencedirect.com/science/article/pii/S1934590919304321
  93. europepmc.org europepmc.org
    Cellular mechanisms of cyclophosphamide-induced taste loss in mice.
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    europepmc.org/articles/PMC5614555/
  94. Feb 2021
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS
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    ncbi.nlm.nih.gov/pmc/articles/PMC7909318/
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Niche-derived soluble DLK1 promotes glioma growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC7587507/
  97. Oct 2020
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Niche-derived soluble DLK1 promotes glioma growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC7587507/
  99. Sep 2020
  100. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Δ9‐Tetrahydrocannabinol promotes oligodendrocyte development and CNS myelination in vivo
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    onlinelibrary.wiley.com/doi/10.1002/glia.23911
  101. academic.oup.com academic.oup.com
    Transient effects of cyclophosphamide on basal cell proliferation of olfactory epithelia
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    academic.oup.com/chemse/advance-article/doi/10.1093/chemse/bjaa039/5856619
  102. academic.oup.com academic.oup.com
    Cyclophosphamide has Long-Term Effects on Proliferation in Olfactory Epithelia
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    academic.oup.com/chemse/advance-article/doi/10.1093/chemse/bjz075/5679498
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TUBB4A mutations result in both glial and neuronal degeneration in an H-ABC leukodystrophy mouse model
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    ncbi.nlm.nih.gov/pmc/articles/PMC7255805/
  104. Jan 2020
  105. www.sciencedirect.com www.sciencedirect.com
    SPARC dependent collagen deposition and gemcitabine delivery in a genetically engineered mouse model of pancreas cancer
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    sciencedirect.com/science/article/pii/S2352396419306280
  106. www.sciencedirect.com www.sciencedirect.com
    Conversion of Astrocytes and Fibroblasts into Functional Noradrenergic Neurons
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    sciencedirect.com/science/article/pii/S2211124719308150
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fractionated head and neck irradiation impacts taste progenitors, differentiated taste cells, and Wnt/β-catenin signaling in adult mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC6884601/
  108. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S1534580719302849
  109. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S1550413119300026
  112. Nov 2018
  113. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S2211124718315808
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ApoE Regulates the Development of Adult Newborn Hippocampal Neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC6072333/
  115. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Hypoxia negatively affects senescence in osteoclasts and delays osteoclastogenesis
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    onlinelibrary.wiley.com/doi/full/10.1002/jcp.26511
  116. dev.biologists.org dev.biologists.org
    Sonic hedgehog from both nerves and epithelium is a key trophic factor for taste bud maintenance
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    dev.biologists.org/content/144/17/3054
  117. www.sciencedirect.com www.sciencedirect.com
    Postnatal Exocrine Pancreas Growth by Cellular Hypertrophy Correlates with a Shorter Lifespan in Mammals
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    sciencedirect.com/science/article/pii/S1534580718304179
  118. www.sciencedirect.com www.sciencedirect.com
    Epithelial Sodium Channel Regulates Adult Neural Stem Cell Proliferation in a Flow-Dependent Manner
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    sciencedirect.com/science/article/pii/S1934590918301784
  119. www.sciencedirect.com www.sciencedirect.com
    A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment
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    sciencedirect.com/science/article/pii/S1535610818301259
  120. www.sciencedirect.com www.sciencedirect.com
    Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency
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    sciencedirect.com/science/article/pii/S1535610817303483
  121. Nov 2017
  122. europepmc.org europepmc.org
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    europepmc.org/articles/PMC5591015/
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    Human iPSC Glial Mouse Chimeras Reveal Glial Contributions to Schizophrenia
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    sciencedirect.com/science/article/pii/S1934590917302382
  124. elifesciences.org elifesciences.org
    Arid1b haploinsufficient mice reveal neuropsychiatric phenotypes and reversible causes of growth impairment
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    elifesciences.org/articles/25730
  125. www.sciencedirect.com www.sciencedirect.com
    MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer
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    Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS
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    sciencedirect.com/science/article/pii/S1535610817302027
  127. www.sciencedirect.com www.sciencedirect.com
    An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice
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    sciencedirect.com/science/article/pii/S1934590917300942