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54.241.53.176 54.241.53.176

NLRP3 inhibition maintains microglia architecture and enhances behavioral recovery after traumatic brain injury

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1. scibot 09 Apr 2026
  
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  AB_2490248
  
  DOI: 10.1101/2025.06.25.660862
  
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54.241.53.176/dd55ce0c9eb00711762194830ace7e7afcb1033f/2025.06.25.660862.full-html.html
Feb 2026
www.sciencedirect.com www.sciencedirect.com

Hepatocyte PLAGL2 deficiency alleviates MASH through MYD88-licensed inactivation of inflammasome

1
1. scibot 20 Feb 2026
  
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  DOI: 10.1016/j.celrep.2026.116942
  
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sciencedirect.com/science/article/pii/S2211124726000203
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Repression of RIPK1 kinase by INPP5D inhibits expression of diverse proinflammatory mediators and late-onset Alzheimer’s disease risk factors

1
1. scibot 03 Feb 2026
  
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  RRID:AB_2490248
  
  DOI: 10.1016/j.immuni.2026.01.014
  
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sciencedirect.com/science/article/pii/S1074761326000361
Jan 2026
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UBE2O-mediated monoubiquitination licenses NLRP6 inflammasome activation in the intestine

1
1. scibot 09 Jan 2026
  
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  RRID:AB_2490248
  
  DOI: 10.1016/j.chom.2025.12.009
  
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sciencedirect.com/science/article/pii/S1931312825005281
Dec 2025
54.241.53.176 54.241.53.176

1-s2.0-S2589004225026197-main-html.html

1
1. scibot 09 Dec 2025
  
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  RRID:AB_2490248
  
  DOI: 10.1016/j.isci.2025.114358
  
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54.241.53.176/ccfdaea90d00d1e2ad4294448fdfaf1320c55233/1-s2.0-S2589004225026197-main-html.html
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The NOX2-ROS-NLRP3 inflammasome axis in traumatic brain injury

1
1. scibot 01 Nov 2025
  
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  RRID:AB_2755041
  
  DOI: 10.1186/s12974-025-03535-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12560392/
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Circulating FABP5 released by dying macrophages function as a DAMP to exacerbate septic inflammation

1
1. scibot 01 Nov 2025
  
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  RRID:AB_2755041
  
  DOI: 10.1016/j.celrep.2025.116497
  
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sciencedirect.com/science/article/pii/S2211124725012689
Oct 2025
link.springer.com link.springer.com

Microglial NLRP3 inflammasome activation leads to perineuronal net loss in cocultured neurons

1
1. scibot 23 Oct 2025
  
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  RRID:AB_2490248
  
  DOI: 10.1007/s11033-025-11145-3
  
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link.springer.com/article/10.1007/s11033-025-11145-3
Sep 2025
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Pathogenic phosphorylation of linear ubiquitin machinery causes inflammasome sensor degradation

1
1. scibot 13 Sep 2025
  
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  RRID:AB_2755041
  
  DOI: 10.1016/j.celrep.2025.116286
  
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sciencedirect.com/science/article/pii/S2211124725010575
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Delayed administration of Jiuwei Qianghuo Decoction combined with Zhuye Shigao Decoction mitigates the severity of influenza A virus infection by inhibiting cell death and alleviating the subsequent cytokine storm response

1
1. scibot 09 Sep 2025
  
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  RRID:AB_2755041
  
  DOI: 10.1016/j.jep.2025.120572
  
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sciencedirect.com/science/article/pii/S0378874125012644
Aug 2025
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Homocysitaconate controls inflammation through reshaping methionine metabolism and N-homocysteinylation

1
1. scibot 28 Aug 2025
  
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  RRID:AB_2490248
  
  DOI: 10.1016/j.cmet.2025.08.001
  
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sciencedirect.com/science/article/pii/S1550413125003572
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NAIP/NLRC4 inflammasome dynamics in murine enteroids are tuned by NAIP ligand concentration and epithelial cell differentiation

1
1. scibot 20 Aug 2025
  
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  RRID:AB_2490248
  
  DOI: 10.1016/j.celrep.2025.116143
  
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sciencedirect.com/science/article/pii/S2211124725009143
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A Potent Inhibitor of Caspase-8 Based on the IL-18 Tetrapeptide Sequence Reveals Shared Specificities between Inflammatory and Apoptotic Initiator Caspases

1
1. scibot 10 Jul 2025
  
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  RRID:AB_2490248
  
  DOI: 10.1021/acsbiomedchemau.4c00146
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12371506/
Jun 2025
www.sciencedirect.com www.sciencedirect.com

RIPK1 senses S-adenosylmethionine scarcity to drive cell death and inflammation

1
1. scibot 26 Jun 2025
  
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  RRID:AB_2490248
  
  DOI: 10.1016/j.cmet.2025.05.014
  
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sciencedirect.com/science/article/pii/S1550413125002943
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Piezo1 senses hyphae and initiates host defense against pathogenic fungi

1
1. scibot 17 Jun 2025
  
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  RRID:AB_2490248
  
  DOI: 10.1016/j.celrep.2025.115839
  
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sciencedirect.com/science/article/pii/S2211124725006102
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Subtilase cytotoxin from Shiga-toxigenic Escherichia coli impairs the inflammasome and exacerbates enteropathogenic bacterial infection

1
1. scibot 14 Jun 2025
  
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  RRID:AB_2755041
  
  DOI: 10.1016/j.isci.2022.104050
  
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sciencedirect.com/science/article/pii/S2589004222003200
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Proliferating Microglia Exhibit Unique Transcriptional and Functional Alterations in Alzheimer’s Disease

1
1. scibot 11 Jun 2025
  
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  RRID:AB_2490248
  
  DOI: 10.1080/17590914.2025.2506406
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12140498/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A bacterial network of T3SS effectors counteracts host pro-inflammatory responses and cell death to promote infection

1
1. scibot 19 May 2025
  
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  RRID:AB_2490248
  
  DOI: 10.1038/s44318-025-00412-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12048508/
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Inflammasome signaling in astrocytes modulates hippocampal plasticity

1
1. scibot 17 May 2025
  
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  RRID:AB_2490248
  
  DOI: 10.1016/j.immuni.2025.04.007
  
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sciencedirect.com/science/article/pii/S1074761325001700
Apr 2025
www.jneurosci.org www.jneurosci.org

Coronin1A regulates the trafficking of alpha synuclein in microglia

1
1. scibot 17 Apr 2025
  
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  RRID:AB_2490248
  
  DOI: 10.1523/JNEUROSCI.1337-24.2025
  
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jneurosci.org/content/45/11/e1337242025
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Type I interferons induce guanylate-binding proteins and lysosomal defense in hepatocytes to control malaria

1
1. scibot 01 Apr 2025
  
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  AB_2490248
  
  DOI: 10.1016/j.chom.2025.03.008
  
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sciencedirect.com/science/article/pii/S1931312825000915
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Pyroptosis of pulmonary fibroblasts and macrophages through NLRC4 inflammasome leads to acute respiratory failure

1
1. scibot 01 Apr 2025
  
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  RRID:AB_2755041
  
  DOI: 10.1016/j.celrep.2025.115479
  
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sciencedirect.com/science/article/pii/S2211124725002505
Mar 2025
www.sciencedirect.com www.sciencedirect.com

The actin and microtubule network regulator WHAMM is identified as a key kidney disease risk gene

1
1. scibot 29 Mar 2025
  
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  RRID:AB_2755041
  
  DOI: 10.1016/j.celrep.2025.115462
  
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sciencedirect.com/science/article/pii/S2211124725002335
Feb 2025
www.sciencedirect.com www.sciencedirect.com

Restraint of inflammasome-driven cytokine responses through the mRNA stability protein TTP

1
1. scibot 25 Feb 2025
  
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  RRID:AB_2490248
  
  DOI: 10.1016/j.celrep.2025.115340
  
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sciencedirect.com/science/article/pii/S2211124725001111
Jan 2025
www.sciencedirect.com www.sciencedirect.com

A cis-regulatory element controls expression of histone deacetylase 9 to fine-tune inflammasome-dependent chronic inflammation in atherosclerosis

1
1. scibot 30 Jan 2025
  
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  RRID:AB_2490248
  
  DOI: 10.1016/j.immuni.2025.01.003
  
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sciencedirect.com/science/article/pii/S1074761325000263
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Plasticity of cell death pathways ensures GSDMD activation during Yersinia pseudotuberculosis infection

1
1. scibot 17 Jan 2025
  
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  RRID:AB_2490248
  
  DOI: 10.1016/j.celrep.2024.115216
  
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sciencedirect.com/science/article/pii/S2211124724015675
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Transplantation of gasdermin pores by extracellular vesicles propagates pyroptosis to bystander cells

1
1. scibot 03 Jan 2025
  
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  RRID:AB_2490248
  
  DOI: 10.1016/j.cell.2024.11.018
  
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sciencedirect.com/science/article/pii/S0092867424013345
Jul 2024
www.sciencedirect.com www.sciencedirect.com

Small molecule inhibitor binds to NOD-like receptor family pyrin domain containing 3 and prevents inflammasome activation

1
1. scibot 18 Jul 2024
  
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  AB_2490248
  
  DOI: 10.1016/j.isci.2024.110459
  
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sciencedirect.com/science/article/pii/S2589004224016845
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

NLRC5 senses NAD+ depletion, forming a PANoptosome and driving PANoptosis and inflammation

1
1. scibot 21 Jun 2024
  
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  RRID:AB_24902348
  
  DOI: 10.1016/j.cell.2024.05.034
  
  Resource: (AdipoGen Cat# AG-20B-0042, RRID:AB_2490248)
  
  Curator: @abever99
  
  SciCrunch record: RRID:AB_2490248
  
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  RRIDCUR:Unresolved RRID:AB_2490248
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ncbi.nlm.nih.gov/pmc/articles/PMC11283362/
Apr 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation

2
1. scibot 09 Apr 2024
  
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  RRID:AB_2755041
  
  DOI: 10.1016/j.celrep.2024.114070
  
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  RRID:AB_2490248
2. scibot 09 Apr 2024
  
  in Public
  
  RRID:AB_2755041
  
  DOI: 10.1016/j.celrep.2024.114070
  
  Resource: (AdipoGen Cat# AG-20B-0042, RRID:AB_2490248)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11130711/
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Disruption of the Na+/K+-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety

1
1. scibot 23 Feb 2024
  
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  RRID:AB_2490248
  
  DOI: 10.1016/j.immuni.2024.01.018
  
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sciencedirect.com/science/article/pii/S107476132400044X
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SERTAD1 initiates NLRP3-mediated inflammasome activation through restricting NLRP3 polyubiquitination

2
1. scibot 13 Feb 2024
  
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  RRID:AB_2490248
  
  DOI: 10.1016/j.celrep.2024.113752
  
  Resource: (AdipoGen Cat# AG-20B-0042, RRID:AB_2490248)
  
  Curator: @scibot
  
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  RRID:AB_2490248
2. scibot 13 Feb 2024
  
  in Public
  
  RRID:AB_2490248
  
  DOI: 10.1016/j.celrep.2024.113752
  
  Resource: (AdipoGen Cat# AG-20B-0042, RRID:AB_2490248)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2490248
  
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sciencedirect.com/science/article/pii/S2211124724000809
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Entrectinib inhibits NLRP3 inflammasome and inflammatory diseases by directly targeting NEK7

1
1. scibot 12 Jan 2024
  
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  RRID:AB_2490248
  
  DOI: 10.1016/j.xcrm.2023.101310
  
  Resource: (AdipoGen Cat# AG-20B-0042, RRID:AB_2490248)
  
  Curator: @scibot
  
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Hepatitis B virus-mediated sodium influx contributes to hepatic inflammation via synergism with intrahepatic danger signals

1
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  DOI: 10.1016/j.isci.2023.108723
  
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Emulsion and liposome-based adjuvanted R21 vaccine formulations mediate protection against malaria through distinct immune mechanisms

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  DOI: 10.1016/j.xcrm.2023.101245
  
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Protocol for in vivo and in vitro activation of NLRP3 inflammasome in mice using monosodium urate

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  DOI: 10.1016/j.xpro.2023.102554
  
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Epigenetic combined with transcriptomic analysis of the m6A methylome after spared nerve injury-induced neuropathic pain in mice

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  DOI: 10.4103/1673-5374.371374
  
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CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout

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  DOI: 10.1016/j.celrep.2023.112265
  
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BPS Publications

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  RRID:AB_2490248
  
  DOI: 10.1111/bph.16036
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16036
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The NLRP1 and CARD8 inflammasomes detect reductive stress

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  DOI: 10.1016/j.celrep.2022.111966
  
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Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation

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Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells

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  DOI: 10.1126/sciadv.abn9912
  
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Kynurenic acid ameliorates NLRP3 inflammasome activation by blocking calcium mobilization via GPR35

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  DOI: 10.3389/fimmu.2022.1019365
  
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Jul 2022
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Inhibition of HDAC6 With CAY10603 Ameliorates Diabetic Kidney Disease by Suppressing NLRP3 Inflammasome

1
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  DOI: 10.3389/fphar.2022.938391
  
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Therapeutic effect of NLRP3 inhibition on hearing loss induced by systemic inflammation in a CAPS-associated mouse model

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  DOI: 10.1016/j.ebiom.2022.104184
  
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BPS Publications

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  DOI: 10.1111/bph.15838
  
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Reconstitution System of NLRP3 Inflammasome in HEK293T Cells

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  DOI: 10.1007/978-1-0716-2144-8_8
  
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Galvanic current activates the NLRP3 inflammasome to promote Type I collagen production in tendon

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K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy

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  DOI: 10.1016/j.celrep.2022.110354
  
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Listeria toxin promotes phosphorylation of the inflammasome adaptor ASC through Lyn and Syk to exacerbate pathogen expansion

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  DOI: 10.1016/j.celrep.2022.110414
  
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Rapid lamellipodial responses by neighbor cells drive epithelial sealing in response to pyroptotic cell death

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  DOI: 10.1016/j.celrep.2022.110316
  
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Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination

1
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  DOI: 10.1016/j.celrep.2021.109904
  
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Sacubitril/Valsartan Alleviates Experimental Autoimmune Myocarditis by Inhibiting Th17 Cell Differentiation Independently of the NLRP3 Inflammasome Pathway

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  DOI: 10.3389/fphar.2021.727838
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8479108/
Aug 2021
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BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology

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  DOI: 10.1016/j.isci.2021.102942
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8369003/
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Untitled document

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  DOI: 10.1016/j.celrep.2018.10.103
  
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The TWIK2 Potassium Efflux Channel in Macrophages Mediates NLRP3 Inflammasome-Induced Inflammation

1
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  RRID: A27351509
  
  DOI: 10.1016/j.immuni.2018.04.032
  
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Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome

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  DOI: 10.1016/j.chembiol.2017.12.013
  
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sciencedirect.com/science/article/pii/S2451945617304622
May 2021
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Histone Deacetylase 3 Couples Mitochondria to Drive IL-1β-Dependent Inflammation by Configuring Fatty Acid Oxidation

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  DOI: 10.1016/j.molcel.2020.08.015
  
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Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases

1
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  DOI: 10.1016/j.celrep.2021.108998
  
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sciencedirect.com/science/article/pii/S2211124721003120
Mar 2021
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Itaconate confers tolerance to late NLRP3 inflammasome activation

1
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  DOI: 10.1016/j.celrep.2021.108756
  
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sciencedirect.com/science/article/pii/S2211124721000693
Feb 2021
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Andrographolide suppresses NLRP3 inflammasome activation in microglia through induction of Parkin-mediated Mitophagy in in-vitro and in-vivo models of Parkinson disease

1
1. scibot 27 Feb 2021
  
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  DOI: 10.1016/j.bbi.2020.09.017
  
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sciencedirect.com/science/article/pii/S0889159120315804
Dec 2020
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Andrographolide suppresses NLRP3 inflammasome activation in microglia through induction of Parkin-mediated Mitophagy in in-vitro and in-vivo models of Parkinson disease

1
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  DOI: 10.1016/j.bbi.2020.09.017
  
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sciencedirect.com/science/article/pii/S0889159120315804
Sep 2020
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Soluble Aβ Oligomers and Protofibrils Induce NLRP3 Inflammasome Activation in Microglia

1
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  DOI: 10.1111/jnc.14945
  
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Targeting Macrophage Histone H3 Modification as a Leishmania Strategy to Dampen the NF-κB/NLRP3-Mediated Inflammatory Response

1
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  DOI: 10.1016/j.celrep.2020.01.030
  
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sciencedirect.com/science/article/pii/S2211124720300450
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Non-canonical Caspase-1 Signaling Drives RIP2-Dependent and TNF-α-Mediated Inflammation In Vivo

1
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  DOI: 10.1016/j.celrep.2020.01.090
  
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Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis

1
1. scibot 16 Sep 2020
  
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  DOI: 10.1016/j.cell.2020.02.002
  
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BPS Publications

1
1. scibot 14 Sep 2020
  
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  RRID:AB_2490248
  
  DOI: 10.1111/bph.15182
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15182
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Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense

1
1. scibot 14 Sep 2020
  
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  RRID:AB_2490248
  
  DOI: 10.1016/j.cell.2020.03.040
  
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sciencedirect.com/science/article/pii/S0092867420303330
Jan 2020
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Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2490248
  
  DOI: 10.1016/j.immuni.2019.04.005
  
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Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation

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1. scibot 13 Jan 2020
  
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  RRID:AB_2490248
  
  DOI: 10.1016/j.ccell.2019.04.003
  
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sciencedirect.com/science/article/pii/S1535610819301989
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Untitled document

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1. scibot 12 Jan 2020
  
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  RRID:AB_2490248
  
  DOI: 10.1016/j.cmet.2019.01.014
  
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sciencedirect.com/science/article/pii/S1550413119300142
Nov 2018
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Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages

1
1. scibot 05 Nov 2018
  
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  2490248
  
  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S1074761318303844
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Regulatory Evolution Drives Evasion of Host Inflammasomes by Salmonella Typhimurium

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1. scibot 05 Nov 2018
  
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  Curator: @Jmenke
  
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Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis

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1. scibot 05 Nov 2018
  
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  RRID:AB_2490248
  
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sciencedirect.com/science/article/pii/S1074761318303261
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Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1931312818302634
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IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2490248
  
  Curator: @Jmenke
  
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The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2490248
  
  Curator: @evieth
  
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Untitled document

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1. scibot 05 Nov 2018
  
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  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5772169/
Nov 2017
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NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation

1
1. scibot 08 Nov 2017
  
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MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation

1
1. scibot 08 Nov 2017
  
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  AB_2490248
  
  Curator: @chewbeccax
  
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A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages

1
1. scibot 08 Nov 2017
  
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  AB_2490248
  
  Curator: @gabimpine
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5409825/
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IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes

1
1. scibot 08 Nov 2017
  
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  AB_2490248
  
  Curator: @gabimpine
  
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sciencedirect.com/science/article/pii/S0092867416312454

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