57 Matching Annotations
  1. Jul 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Small molecule inhibitor binds to NOD-like receptor family pyrin domain containing 3 and prevents inflammasome activation
    1
    1. scibot 18 Jul 2024
      AB_2490248

      DOI: 10.1016/j.isci.2024.110459

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    sciencedirect.com/science/article/pii/S2589004224016845
  3. Jun 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRC5 senses NAD+ depletion, forming a PANoptosome and driving PANoptosis and inflammation
    1
    1. scibot 21 Jun 2024
      RRID:AB_24902348

      DOI: 10.1016/j.cell.2024.05.034

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    ncbi.nlm.nih.gov/pmc/articles/PMC11283362/
  5. Apr 2024
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation
    2
    1. scibot 09 Apr 2024
      RRID:AB_2755041

      DOI: 10.1016/j.celrep.2024.114070

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    2. scibot 09 Apr 2024
      RRID:AB_2755041

      DOI: 10.1016/j.celrep.2024.114070

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    pmc.ncbi.nlm.nih.gov/articles/PMC11130711/
  7. Feb 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Disruption of the Na+/K+-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety
    1
    1. scibot 23 Feb 2024
      RRID:AB_2490248

      DOI: 10.1016/j.immuni.2024.01.018

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    sciencedirect.com/science/article/pii/S107476132400044X
  9. www.sciencedirect.com www.sciencedirect.com
    SERTAD1 initiates NLRP3-mediated inflammasome activation through restricting NLRP3 polyubiquitination
    2
    1. scibot 13 Feb 2024
      RRID:AB_2490248

      DOI: 10.1016/j.celrep.2024.113752

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    2. scibot 13 Feb 2024
      RRID:AB_2490248

      DOI: 10.1016/j.celrep.2024.113752

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    sciencedirect.com/science/article/pii/S2211124724000809
  10. Jan 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Entrectinib inhibits NLRP3 inflammasome and inflammatory diseases by directly targeting NEK7
    1
    1. scibot 12 Jan 2024
      RRID:AB_2490248

      DOI: 10.1016/j.xcrm.2023.101310

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    ncbi.nlm.nih.gov/pmc/articles/PMC10772347/
  12. www.sciencedirect.com www.sciencedirect.com
    Hepatitis B virus-mediated sodium influx contributes to hepatic inflammation via synergism with intrahepatic danger signals
    1
    1. scibot 11 Jan 2024
      RRID:AB_2490248

      DOI: 10.1016/j.isci.2023.108723

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    sciencedirect.com/science/article/pii/S2589004223028006
  13. Dec 2023
  14. www.sciencedirect.com www.sciencedirect.com
    Emulsion and liposome-based adjuvanted R21 vaccine formulations mediate protection against malaria through distinct immune mechanisms
    1
    1. scibot 02 Dec 2023
      RRID:AB_2490248

      DOI: 10.1016/j.xcrm.2023.101245

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    sciencedirect.com/science/article/pii/S2666379123004226
  15. Sep 2023
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol for in vivo and in vitro activation of NLRP3 inflammasome in mice using monosodium urate
    1
    1. scibot 17 Sep 2023
      RRID:AB_2490248

      DOI: 10.1016/j.xpro.2023.102554

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    ncbi.nlm.nih.gov/pmc/articles/PMC10493585/
  17. Jul 2023
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic combined with transcriptomic analysis of the m6A methylome after spared nerve injury-induced neuropathic pain in mice
    1
    1. scibot 25 Jul 2023
      RRID:AB_2490248

      DOI: 10.4103/1673-5374.371374

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    ncbi.nlm.nih.gov/pmc/articles/PMC10360113/
  19. Mar 2023
  20. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout
    1
    1. scibot 17 Mar 2023
      RRID:AB_2490248

      DOI: 10.1016/j.celrep.2023.112265

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    pubmed.ncbi.nlm.nih.gov/36930645/
  21. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 03 Mar 2023
      RRID:AB_2490248

      DOI: 10.1111/bph.16036

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16036
  22. Jan 2023
  23. www.sciencedirect.com www.sciencedirect.com
    The NLRP1 and CARD8 inflammasomes detect reductive stress
    1
    1. scibot 19 Jan 2023
      RRID:AB_2490248

      DOI: 10.1016/j.celrep.2022.111966

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    sciencedirect.com/science/article/pii/S2211124722018708
  24. www.sciencedirect.com www.sciencedirect.com
    Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation
    1
    1. scibot 11 Jan 2023
      RRID:AB_2490248

      DOI: 10.1016/j.celrep.2022.111941

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    sciencedirect.com/science/article/pii/S2211124722018423
  25. Nov 2022
  26. www.science.org www.science.org
    Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells
    1
    1. scibot 15 Nov 2022
      RRID:AB_2490248

      DOI: 10.1126/sciadv.abn9912

      Resource: (AdipoGen Cat# AG-20B-0042, RRID:AB_2490248)

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    science.org/doi/10.1126/sciadv.abn9912
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kynurenic acid ameliorates NLRP3 inflammasome activation by blocking calcium mobilization via GPR35
    1
    1. scibot 02 Nov 2022
      RRID:AB_2490248

      DOI: 10.3389/fimmu.2022.1019365

      Resource: (AdipoGen Cat# AG-20B-0042, RRID:AB_2490248)

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    ncbi.nlm.nih.gov/pmc/articles/PMC9606686/
  28. Jul 2022
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of HDAC6 With CAY10603 Ameliorates Diabetic Kidney Disease by Suppressing NLRP3 Inflammasome
    1
    1. scibot 31 Jul 2022
      RRID:AB_2490248

      DOI: 10.3389/fphar.2022.938391

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    ncbi.nlm.nih.gov/pmc/articles/PMC9332914/
  30. www.sciencedirect.com www.sciencedirect.com
    Therapeutic effect of NLRP3 inhibition on hearing loss induced by systemic inflammation in a CAPS-associated mouse model
    1
    1. scibot 27 Jul 2022
      RRID:AB_2490248

      DOI: 10.1016/j.ebiom.2022.104184

      Resource: (AdipoGen Cat# AG-20B-0042, RRID:AB_2490248)

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    sciencedirect.com/science/article/pii/S2352396422003656
  31. Apr 2022
  32. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 28 Apr 2022
      RRID:AB_2490248

      DOI: 10.1111/bph.15838

      Resource: (AdipoGen Cat# AG-20B-0042, RRID:AB_2490248)

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15838
  33. Mar 2022
  34. link.springer.com link.springer.com
    Reconstitution System of NLRP3 Inflammasome in HEK293T Cells
    1
    1. scibot 23 Mar 2022
      RRID:AB_2490248

      DOI: 10.1007/978-1-0716-2144-8_8

      Resource: (AdipoGen Cat# AG-20B-0042, RRID:AB_2490248)

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    link.springer.com/protocol/10.1007/978-1-0716-2144-8_8
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Galvanic current activates the NLRP3 inflammasome to promote Type I collagen production in tendon
    1
    1. scibot 09 Mar 2022
      RRID:AB_2490248

      DOI: 10.7554/eLife.73675

      Resource: (AdipoGen Cat# AG-20B-0042, RRID:AB_2490248)

      Curator: @scibot

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    ncbi.nlm.nih.gov/pmc/articles/PMC8896827/
  36. www.sciencedirect.com www.sciencedirect.com
    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
    1
    1. scibot 04 Mar 2022
      Adipogen cat# AG-20B-0042

      DOI: 10.1016/j.celrep.2022.110354

      Resource: (AdipoGen Cat# AG-20B-0042, RRID:AB_2490248)

      Curator: @sophiastull

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    sciencedirect.com/science/article/pii/S2211124722000705
  37. Feb 2022
  38. www.sciencedirect.com www.sciencedirect.com
    Listeria toxin promotes phosphorylation of the inflammasome adaptor ASC through Lyn and Syk to exacerbate pathogen expansion
    1
    1. scibot 23 Feb 2022
      RRID:AB_2490248

      DOI: 10.1016/j.celrep.2022.110414

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    sciencedirect.com/science/article/pii/S2211124722001383
  39. www.sciencedirect.com www.sciencedirect.com
    Rapid lamellipodial responses by neighbor cells drive epithelial sealing in response to pyroptotic cell death
    1
    1. scibot 02 Feb 2022
      RRID:AB_2490248

      DOI: 10.1016/j.celrep.2022.110316

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    sciencedirect.com/science/article/pii/S2211124722000274
  40. Oct 2021
  41. www.sciencedirect.com www.sciencedirect.com
    Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination
    1
    1. scibot 30 Oct 2021
      RRID:AB_2490248

      DOI: 10.1016/j.celrep.2021.109904

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    sciencedirect.com/science/article/pii/S2211124721013747
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sacubitril/Valsartan Alleviates Experimental Autoimmune Myocarditis by Inhibiting Th17 Cell Differentiation Independently of the NLRP3 Inflammasome Pathway
    1
    1. scibot 02 Oct 2021
      RRID:AB_2490248

      DOI: 10.3389/fphar.2021.727838

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    ncbi.nlm.nih.gov/pmc/articles/PMC8479108/
  43. Aug 2021
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology
    1
    1. scibot 25 Aug 2021
      RRID:AB_2490248

      DOI: 10.1016/j.isci.2021.102942

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    ncbi.nlm.nih.gov/pmc/articles/PMC8369003/
  45. Jul 2021
  46. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 30 Jul 2021
      RRID:AB_2490248

      DOI: 10.1016/j.celrep.2018.10.103

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    sciencedirect.com/science/article/pii/S221112471831725X
  47. www.sciencedirect.com www.sciencedirect.com
    The TWIK2 Potassium Efflux Channel in Macrophages Mediates NLRP3 Inflammasome-Induced Inflammation
    1
    1. scibot 27 Jul 2021
      RRID: A27351509

      DOI: 10.1016/j.immuni.2018.04.032

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      Curator: @Jmenke

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      RRID:AB_2490248 RRIDCUR:Incorrect
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    sciencedirect.com/science/article/pii/S1074761318302036
  48. www.sciencedirect.com www.sciencedirect.com
    Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome
    1
    1. scibot 27 Jul 2021
      RRID:AB_249024

      DOI: 10.1016/j.chembiol.2017.12.013

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      Curator: @Jmenke

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      RRIDCUR:Incorrect RRIDCUR:Unresolved RRID:AB_2490248
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    sciencedirect.com/science/article/pii/S2451945617304622
  49. May 2021
  50. www.sciencedirect.com www.sciencedirect.com
    Histone Deacetylase 3 Couples Mitochondria to Drive IL-1β-Dependent Inflammation by Configuring Fatty Acid Oxidation
    1
    1. scibot 07 May 2021
      RRID:AB_2490248

      DOI: 10.1016/j.molcel.2020.08.015

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    sciencedirect.com/science/article/pii/S1097276520305785
  51. Apr 2021
  52. www.sciencedirect.com www.sciencedirect.com
    Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases
    1
    1. scibot 14 Apr 2021
      RRID:AB_2490248

      DOI: 10.1016/j.celrep.2021.108998

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      Curator: @Naa003

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      RRIDCUR:Validated RRID:AB_2490248
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    sciencedirect.com/science/article/pii/S2211124721003120
  53. Mar 2021
  54. www.sciencedirect.com www.sciencedirect.com
    Itaconate confers tolerance to late NLRP3 inflammasome activation
    1
    1. scibot 10 Mar 2021
      RRID:AB_2490248

      DOI: 10.1016/j.celrep.2021.108756

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    sciencedirect.com/science/article/pii/S2211124721000693
  55. Feb 2021
  56. www.sciencedirect.com www.sciencedirect.com
    Andrographolide suppresses NLRP3 inflammasome activation in microglia through induction of Parkin-mediated Mitophagy in in-vitro and in-vivo models of Parkinson disease
    1
    1. scibot 27 Feb 2021
      RRID:AB_2490248

      DOI: 10.1016/j.bbi.2020.09.017

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    sciencedirect.com/science/article/pii/S0889159120315804
  57. Dec 2020
  58. www.sciencedirect.com www.sciencedirect.com
    Andrographolide suppresses NLRP3 inflammasome activation in microglia through induction of Parkin-mediated Mitophagy in in-vitro and in-vivo models of Parkinson disease
    1
    1. scibot 17 Dec 2020
      RRID:AB_2490248

      DOI: 10.1016/j.bbi.2020.09.017

      Resource: (AdipoGen Cat# AG-20B-0042, RRID:AB_2490248)

      Curator: @Naa003

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      Curator comments: anti-Caspase-1 (p20) (mouse) mAb (Casper-1) antibody AdipoGen Cat# AG-20B-0042

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    sciencedirect.com/science/article/pii/S0889159120315804
  59. Sep 2020
  60. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Soluble Aβ Oligomers and Protofibrils Induce NLRP3 Inflammasome Activation in Microglia
    1
    1. scibot 23 Sep 2020
      RRID:AB_2490248

      DOI: 10.1111/jnc.14945

      Resource: (AdipoGen Cat# AG-20B-0042, RRID:AB_2490248)

      Curator: @ethanbadger

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      RRID:AB_2490248 RRIDCUR:Validated
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14945
  61. www.sciencedirect.com www.sciencedirect.com
    Targeting Macrophage Histone H3 Modification as a Leishmania Strategy to Dampen the NF-κB/NLRP3-Mediated Inflammatory Response
    1
    1. scibot 17 Sep 2020
      RRID:AB_2490248

      DOI: 10.1016/j.celrep.2020.01.030

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    sciencedirect.com/science/article/pii/S2211124720300450
  62. www.sciencedirect.com www.sciencedirect.com
    Non-canonical Caspase-1 Signaling Drives RIP2-Dependent and TNF-α-Mediated Inflammation In Vivo
    1
    1. scibot 16 Sep 2020
      RRID:AB_2490248

      DOI: 10.1016/j.celrep.2020.01.090

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  63. www.sciencedirect.com www.sciencedirect.com
    Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis
    1
    1. scibot 16 Sep 2020
      RRID:AB_2490248

      DOI: 10.1016/j.cell.2020.02.002

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    sciencedirect.com/science/article/pii/S009286742030146X
  64. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 14 Sep 2020
      RRID:AB_2490248

      DOI: 10.1111/bph.15182

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15182
  65. www.sciencedirect.com www.sciencedirect.com
    Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
    1
    1. scibot 14 Sep 2020
      RRID:AB_2490248

      DOI: 10.1016/j.cell.2020.03.040

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    sciencedirect.com/science/article/pii/S0092867420303330
  66. Jan 2020
  67. www.sciencedirect.com www.sciencedirect.com
    Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM
    1
    1. scibot 13 Jan 2020
      RRID:AB_2490248

      DOI: 10.1016/j.immuni.2019.04.005

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    sciencedirect.com/science/article/pii/S1074761319301852
  68. www.sciencedirect.com www.sciencedirect.com
    Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation
    1
    1. scibot 13 Jan 2020
      RRID:AB_2490248

      DOI: 10.1016/j.ccell.2019.04.003

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    sciencedirect.com/science/article/pii/S1535610819301989
  69. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 12 Jan 2020
      RRID:AB_2490248

      DOI: 10.1016/j.cmet.2019.01.014

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    sciencedirect.com/science/article/pii/S1550413119300142
  70. Nov 2018
  71. www.sciencedirect.com www.sciencedirect.com
    Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages
    1
    1. scibot 05 Nov 2018
      2490248

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1074761318303844
  72. www.sciencedirect.com www.sciencedirect.com
    Regulatory Evolution Drives Evasion of Host Inflammasomes by Salmonella Typhimurium
    1
    1. scibot 05 Nov 2018
      RRID:AB_2490248

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S2211124718315389
  73. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis
    1
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      RRID:AB_2490248

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    sciencedirect.com/science/article/pii/S1074761318303261
  74. www.sciencedirect.com www.sciencedirect.com
    Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis
    1
    1. scibot 05 Nov 2018
      RRID:AB_2490248

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    sciencedirect.com/science/article/pii/S1931312818302634
  75. www.sciencedirect.com www.sciencedirect.com
    IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation
    1
    1. scibot 05 Nov 2018
      RRID:AB_2490248

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0092867418302320
  76. www.sciencedirect.com www.sciencedirect.com
    The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages
    1
    1. scibot 05 Nov 2018
      RRID:AB_2490248

      Curator: @evieth

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    sciencedirect.com/science/article/pii/S107476131730568X
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 05 Nov 2018
      RRID:AB_2490248

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC5772169/
  78. Nov 2017
  79. www.sciencedirect.com www.sciencedirect.com
    NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation
    1
    1. scibot 08 Nov 2017
      RRID:AB_2490248

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276517306147
  80. www.sciencedirect.com www.sciencedirect.com
    MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation
    1
    1. scibot 08 Nov 2017
      AB_2490248

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S1074761317302285
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages
    1
    1. scibot 08 Nov 2017
      AB_2490248

      Curator: @gabimpine

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      (AdipoGen Cat# AG-20B-0042, RRID:AB_2490248)

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    ncbi.nlm.nih.gov/pmc/articles/PMC5409825/
  82. www.sciencedirect.com www.sciencedirect.com
    IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes
    1
    1. scibot 08 Nov 2017
      AB_2490248

      Curator: @gabimpine

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      (AdipoGen Cat# AG-20B-0042, RRID:AB_2490248)

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    sciencedirect.com/science/article/pii/S0092867416312454