46 Matching Annotations
  1. Jun 2024
  2. www.sciencedirect.com www.sciencedirect.com
    NLRC5 senses NAD+ depletion, forming a PANoptosome and driving PANoptosis and inflammation
    1
    1. scibot 21 Jun 2024
      RRID:AB_2885200

      DOI: 10.1016/j.cell.2024.05.034

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    sciencedirect.com/science/article/pii/S0092867424005786
  3. Apr 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Truncating NFKB1 variants cause combined NLRP3 inflammasome activation and type I interferon signaling and predispose to necrotizing fasciitis
    2
    1. scibot 09 Apr 2024
      RRID:AB_2885200

      DOI: 10.1016/j.xcrm.2024.101503

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    2. scibot 09 Apr 2024
      RRID:AB_2885200

      DOI: 10.1016/j.xcrm.2024.101503

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    sciencedirect.com/science/article/pii/S2666379124001721
  5. Feb 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Disruption of the Na+/K+-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety
    1
    1. scibot 23 Feb 2024
      RRID:AB_2490440

      DOI: 10.1016/j.immuni.2024.01.018

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    sciencedirect.com/science/article/pii/S107476132400044X
  7. Nov 2023
  8. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis
    1
    1. scibot 10 Nov 2023
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      DOI: 10.1016/j.immuni.2023.10.004

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    sciencedirect.com/science/article/pii/S1074761323004442
  9. www.nature.com www.nature.com
    Cryo-electron tomography of NLRP3-activated ASC complexes reveals organelle co-localization
    1
    1. scibot 10 Nov 2023
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      DOI: 10.1038/s41467-023-43180-8

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    nature.com/articles/s41467-023-43180-8
  10. Mar 2023
  11. onlinelibrary.wiley.com onlinelibrary.wiley.com
    NLRP3-directed antisense oligonucleotides reduce microglial immunoactivities in vitro
    1
    1. scibot 30 Mar 2023
      RRID:AB_2490440

      DOI: 10.1111/jnc.15778

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15778
  12. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout
    1
    1. scibot 17 Mar 2023
      RRID:AB_2490440

      DOI: 10.1016/j.celrep.2023.112265

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    pubmed.ncbi.nlm.nih.gov/36930645/
  13. Jan 2023
  14. www.sciencedirect.com www.sciencedirect.com
    The NLRP1 and CARD8 inflammasomes detect reductive stress
    1
    1. scibot 19 Jan 2023
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      DOI: 10.1016/j.celrep.2022.111966

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    sciencedirect.com/science/article/pii/S2211124722018708
  15. www.sciencedirect.com www.sciencedirect.com
    Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation
    1
    1. scibot 11 Jan 2023
      RRID:AB_2490440

      DOI: 10.1016/j.celrep.2022.111941

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    sciencedirect.com/science/article/pii/S2211124722018423
  16. Nov 2022
  17. www.sciencedirect.com www.sciencedirect.com
    Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
    1
    1. scibot 24 Nov 2022
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      DOI: 10.1016/j.celrep.2022.111688

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    sciencedirect.com/science/article/pii/S2211124722015625
  18. www.science.org www.science.org
    Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells
    1
    1. scibot 15 Nov 2022
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      DOI: 10.1126/sciadv.abn9912

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    science.org/doi/10.1126/sciadv.abn9912
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection
    1
    1. scibot 04 Nov 2022
      RRID:AB_2490440

      DOI: 10.1084/jem.20220837

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    ncbi.nlm.nih.gov/pmc/articles/PMC9623368/
  20. Mar 2022
  21. link.springer.com link.springer.com
    Reconstitution System of NLRP3 Inflammasome in HEK293T Cells
    1
    1. scibot 23 Mar 2022
      RRID:AB_2490440

      DOI: 10.1007/978-1-0716-2144-8_8

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    link.springer.com/protocol/10.1007/978-1-0716-2144-8_8
  22. Feb 2022
  23. www.sciencedirect.com www.sciencedirect.com
    Listeria toxin promotes phosphorylation of the inflammasome adaptor ASC through Lyn and Syk to exacerbate pathogen expansion
    1
    1. scibot 23 Feb 2022
      RRID:AB_2490440

      DOI: 10.1016/j.celrep.2022.110414

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    sciencedirect.com/science/article/pii/S2211124722001383
  24. Oct 2021
  25. www.sciencedirect.com www.sciencedirect.com
    Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination
    1
    1. scibot 30 Oct 2021
      RRID:AB_2490440

      DOI: 10.1016/j.celrep.2021.109904

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    sciencedirect.com/science/article/pii/S2211124721013747
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synthetic amyloid-β oligomers drive early pathological progression of Alzheimer’s disease in nonhuman primates
    1
    1. scibot 28 Oct 2021
      RRID:AB_2490440

      DOI: 10.1016/j.isci.2021.103207

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    ncbi.nlm.nih.gov/pmc/articles/PMC8524197/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sacubitril/Valsartan Alleviates Experimental Autoimmune Myocarditis by Inhibiting Th17 Cell Differentiation Independently of the NLRP3 Inflammasome Pathway
    1
    1. scibot 02 Oct 2021
      AB_2490440

      DOI: 10.3389/fphar.2021.727838

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    ncbi.nlm.nih.gov/pmc/articles/PMC8479108/
  28. Aug 2021
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Shigella OspC3 suppresses murine cytosolic LPS sensing
    1
    1. scibot 19 Aug 2021
      RRID:AB_2490440

      DOI: 10.1016/j.isci.2021.102910

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    ncbi.nlm.nih.gov/pmc/articles/PMC8361271/
  30. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 08 Aug 2021
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      DOI: 10.1016/j.celrep.2018.09.071

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    sciencedirect.com/science/article/pii/S2211124718315316
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 06 Aug 2021
      RRID:AB_2490440

      DOI: 10.1016/j.immuni.2019.02.006

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    ncbi.nlm.nih.gov/pmc/articles/PMC6477154/
  32. Jul 2021
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 31 Jul 2021
      RRID:AB_2490440

      DOI: 10.1016/j.celrep.2019.03.100

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    ncbi.nlm.nih.gov/pmc/articles/PMC6486487/
  34. www.sciencedirect.com www.sciencedirect.com
    The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection
    1
    1. scibot 30 Jul 2021
      RRID:AB_2490440

      DOI: 10.1016/j.cell.2018.09.047

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    sciencedirect.com/science/article/pii/S0092867418312595
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice
    1
    1. scibot 08 Jul 2021
      RRID:AB_2490440

      DOI: 10.7554/eLife.66522

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    ncbi.nlm.nih.gov/pmc/articles/PMC8245129/
  36. May 2021
  37. www.sciencedirect.com www.sciencedirect.com
    Histone Deacetylase 3 Couples Mitochondria to Drive IL-1β-Dependent Inflammation by Configuring Fatty Acid Oxidation
    1
    1. scibot 07 May 2021
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      DOI: 10.1016/j.molcel.2020.08.015

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    sciencedirect.com/science/article/pii/S1097276520305785
  38. www.sciencedirect.com www.sciencedirect.com
    Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis
    1
    1. scibot 06 May 2021
      RRID:AB_2490440

      DOI: 10.1016/j.immuni.2020.04.010

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    sciencedirect.com/science/article/pii/S1074761320301680
  39. www.sciencedirect.com www.sciencedirect.com
    DNA Damage Promotes Epithelial Hyperplasia and Fate Mis-specification via Fibroblast Inflammasome Activation
    1
    1. scibot 05 May 2021
      RRID:AB_2490440

      DOI: 10.1016/j.devcel.2020.09.021

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    sciencedirect.com/science/article/pii/S153458072030753X
  40. Mar 2021
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pin1 Promotes NLRP3 Inflammasome Activation by Phosphorylation of p38 MAPK Pathway in Septic Shock
    1
    1. scibot 13 Mar 2021
      AB_2490440

      DOI: 10.3389/fimmu.2021.620238

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    ncbi.nlm.nih.gov/pmc/articles/PMC7947244/
  42. Feb 2021
  43. www.nature.com www.nature.com
    A comprehensive guide to studying inflammasome activation and cell death
    1
    1. scibot 26 Feb 2021
      RRID:AB_2490440

      DOI: 10.1038/s41596-020-0374-9

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    nature.com/articles/s41596-020-0374-9
  44. onlinelibrary.wiley.com onlinelibrary.wiley.com
    α‐Synuclein evokes NLRP3 inflammasome‐mediated IL‐1β secretion from primary human microglia
    2
    1. scibot 02 Feb 2021
      RRID:AB_2490440

      DOI: 10.1002/glia.23970

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    2. scibot 02 Feb 2021
      RRID:AB_2490440

      DOI: 10.1002/glia.23970

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    onlinelibrary.wiley.com/doi/10.1002/glia.23970
  45. Nov 2020
  46. www.sciencedirect.com www.sciencedirect.com
    Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity
    1
    1. scibot 24 Nov 2020
      RRID:AB_2490440

      DOI: 10.1016/j.celrep.2020.108381

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    sciencedirect.com/science/article/pii/S221112472031370X
  47. Sep 2020
  48. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Soluble Aβ Oligomers and Protofibrils Induce NLRP3 Inflammasome Activation in Microglia
    1
    1. scibot 23 Sep 2020
      RRID:AB_2490440

      DOI: 10.1111/jnc.14945

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14945
  49. www.sciencedirect.com www.sciencedirect.com
    β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia
    1
    1. scibot 16 Sep 2020
      RRID:AB_2490440

      DOI: 10.1016/j.celrep.2020.02.025

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    sciencedirect.com/science/article/pii/S2211124720301868
  50. www.sciencedirect.com www.sciencedirect.com
    FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells
    1
    1. scibot 15 Sep 2020
      RRID:AB_2490440

      DOI: 10.1016/j.immuni.2020.04.002

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    sciencedirect.com/science/article/pii/S1074761320301606
  51. www.sciencedirect.com www.sciencedirect.com
    An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages
    1
    1. scibot 15 Sep 2020
      RRID:AB_2490440

      DOI: 10.1016/j.celrep.2020.107959

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    sciencedirect.com/science/article/pii/S2211124720309402
  52. Jan 2020
  53. www.sciencedirect.com www.sciencedirect.com
    Adrenergic Signaling in Muscularis Macrophages Limits Infection-Induced Neuronal Loss
    1
    1. scibot 13 Jan 2020
      RRID:AB_2490440

      DOI: 10.1016/j.cell.2019.12.002

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    sciencedirect.com/science/article/pii/S0092867419313285
  54. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2490440

      DOI: 10.1016/j.immuni.2019.02.006

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    sciencedirect.com/science/article/pii/S107476131930072X
  55. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2490440

      DOI: 10.1016/j.celrep.2019.03.100

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    sciencedirect.com/science/article/pii/S2211124719304474
  56. Nov 2018
  57. www.sciencedirect.com www.sciencedirect.com
    Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages
    1
    1. scibot 05 Nov 2018
      RRID:AB_2490440

      Curator: @Jmenke

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      SciCrunch record: RRID:AB_2490440

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      RRID:AB_2490440 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1074761318303844
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Method for the Acute and Rapid Degradation of Endogenous Proteins
    2
    1. scibot 05 Nov 2018
      RRID:AB_2490440

      Curator: @evieth

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      (AdipoGen Cat# AG-25B-0006, RRID:AB_2490440)

      SciCrunch record: RRID:AB_2490440

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      RRID:AB_2490440 RRIDCUR:Validated
    2. scibot 05 Nov 2018
      RRID:AB_2490440

      Curator: @evieth

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      (AdipoGen Cat# AG-25B-0006, RRID:AB_2490440)

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      RRID:AB_2490440 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC5733393/
  59. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Activation of the NLRP3 inflammasome in microglia: the role of ceramide
    1
    1. scibot 05 Nov 2018
      RRID:AB_2490440

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      (AdipoGen Cat# AG-25B-0006, RRID:AB_2490440)

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      RRID:AB_2490440
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14225/full
  60. Nov 2017
  61. www.sciencedirect.com www.sciencedirect.com
    Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function
    1
    1. scibot 08 Nov 2017
      AB_2490440

      Curator: @chewbeccax

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      (AdipoGen Cat# AG-25B-0006, RRID:AB_2490440)

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      RRID:AB_2490440 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1074761317302777
  62. www.sciencedirect.com www.sciencedirect.com
    Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation
    1
    1. scibot 08 Nov 2017
      AB_2490440

      Curator: @gabimpine

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      (AdipoGen Cat# AG-25B-0006, RRID:AB_2490440)

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      RRID:AB_2490440 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867416312296
  63. www.sciencedirect.com www.sciencedirect.com
    IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes
    1
    1. scibot 08 Nov 2017
      AB_2490440

      Curator: @gabimpine

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      (AdipoGen Cat# AG-25B-0006, RRID:AB_2490440)

      SciCrunch record: RRID:AB_2490440

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      RRID:AB_2490440 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867416312454