536 Matching Annotations
  1. Aug 2025
  2. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225016840-main-html.html
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  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SMAD4 Deficiency Promotes Pancreatic Cancer Progression and Confers Susceptibility to TGFβ Inhibition
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    pmc.ncbi.nlm.nih.gov/articles/PMC12355175/
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    ER-phagy and proteostasis defects prime pancreatic epithelial state changes in KRAS-mediated oncogenesis
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    sciencedirect.com/science/article/pii/S1534580725004733
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    Dietary-dependent sensitization of neuronal leptin signaling promotes neural repair after injury via cAMP and gene transcription
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    sciencedirect.com/science/article/pii/S0896627325005239
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Plasma hepcidin level is elevated by water immersion‐induced central fatigue via hepatic inflammatory response in male and female rats
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    pmc.ncbi.nlm.nih.gov/articles/PMC12320131/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuronal Reg3β/macrophage TNF-α–mediated positive feedback signaling contributes to pain chronicity in a rat model of CRPS-I
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    pmc.ncbi.nlm.nih.gov/articles/PMC12315989/
  8. www.science.org www.science.org
    Neuronal Reg3β/macrophage TNF-α–mediated positive feedback signaling contributes to pain chronicity in a rat model of CRPS-I
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    science.org/doi/10.1126/sciadv.adu4270
  9. Jul 2025
  10. www.science.org www.science.org
    Distinct adipose progenitor cells emerging with age drive active adipogenesis
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    science.org/doi/10.1126/science.adj0430
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MSN/STAT3 drives cancer stemness and chemoresistance via IL-6/LPAR1 ligand receptor complex in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12281688/
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    Cancer-associated fibroblast-derived fibulin-5 promotes radioresistance in non-small-cell lung cancer
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    sciencedirect.com/science/article/pii/S2211124725007892
  13. 52.53.155.43 52.53.155.43
    Organoid modeling reveals the tumorigenic potential of the alveolar progenitor cell state
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    52.53.155.43/1c70dafeeeda06325918fe95f6455c023d1ce5ae/March-2025-Carla-Kim-li-et-al-2025-organoid-modeling-reveals-the-tumorigenic-potential-of-the-alveolar-progenitor-cell-state-html.html
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    A STAT3/integrin axis accelerates pancreatic cancer initiation and progression
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    sciencedirect.com/science/article/pii/S2211124725007818
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    Targeting Triple-Negative Breast Cancer with Momordicine-I for Therapeutic Gain in Preclinical Models
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    mdpi.com/2072-6694/17/14/2342
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    Augment proteasome inhibitor efficacy activates CD8+ T cell-mediated antitumor immunity in breast cancer
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    sciencedirect.com/science/article/pii/S2666379125002848
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nutritionally Responsive PMv DAT Neurons Are Dynamically Regulated During Pubertal Transition
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    pmc.ncbi.nlm.nih.gov/articles/PMC12204309/
  18. Jun 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An Acrolein-Based Drug Delivery System Enables Tumor-Specific Sphingosine-1-Phosphate Targeting in Breast Cancer without Lymphocytopenia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12174973/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer’s disease through disrupted regulated intramembrane proteolysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12181884/
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    Redundancy of the OST catalytic subunit facilitates therapeutic targeting of N-glycosylation
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    sciencedirect.com/science/article/pii/S2451945625001667
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    Efflux of N1-acetylspermidine from hepatoma fosters macrophage-mediated immune suppression to dampen immunotherapeutic efficacy
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    sciencedirect.com/science/article/pii/S1074761325002274
  23. May 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Indole-3-lactic acid suppresses colorectal cancer via metabolic reprogramming
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    pmc.ncbi.nlm.nih.gov/articles/PMC12118437/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GuBenPeiYuan Formula Inhibits Lung Cancer Metastasis by Suppressing Myeloid-Derived Suppressor Cells and Related Immune Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12035261/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TNF‐α‐Driven Changes in Polarized EGF Receptor Trafficking Facilitate Phosphatidylinositol 3‐Kinase/Protein Kinase B Signaling From the Apical Surface of MDCK Epithelial Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12052438/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Memory T‐Cell Phenotype in Cutaneous T‐Cell Lymphoma Is Modified by Germline Gene Gametocyte Specific Factor 1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12078864/
  28. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel synthesised STAT3 inhibitor exerts potent anti-tumour activity by inducing lysosome-dependent cell death
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70071
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    Genetic biomarker study of sunvozertinib for clinical prognosis and prediction in NSCLC with EGFR exon 20 insertion mutation
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    sciencedirect.com/science/article/pii/S2666379125001946
  30. Apr 2025
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Time Release Ion Matrix Regenerates Dystrophic Skeletal Muscle
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    pmc.ncbi.nlm.nih.gov/articles/PMC11957216/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A leptin receptor mutation which impairs fertility in ewes causes delayed puberty in male and female mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11979093/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lineage Tracing and Single-Cell RNA Sequencing Reveal a Common Transcriptional State in Breast Cancer Tumor–Initiating Cells Characterized by IFN/STAT1 Activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11997551/
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    Mitochondrial DNA released by senescent tumor cells enhances PMN-MDSC-driven immunosuppression through the cGAS-STING pathway
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    sciencedirect.com/science/article/pii/S1074761325001244
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A single amino acid in the Salmonella effector SarA/SteE triggers supraphysiological activation of STAT3 for anti-inflammatory gene expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12014907/
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    STAT3 signaling enhances tissue expansion during postimplantation mouse development
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    sciencedirect.com/science/article/pii/S2211124725002773
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fatty acid uptake activates an AXL–CAV1–β-catenin axis to drive melanoma progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11960706/
  38. www.nature.com www.nature.com
    Jorunnamycin A induces apoptosis in pancreatic ductal adenocarcinoma cells, spheroids, and patient-derived organoids by modulating KRAS-mediated survival pathways
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    nature.com/articles/s41598-025-95766-5
  39. Mar 2025
  40. www.sciencedirect.com www.sciencedirect.com
    Lactylation of LSD1 is an acquired epigenetic vulnerability of BRAFi/MEKi-resistant melanoma
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    sciencedirect.com/science/article/pii/S1534580725001212
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    Therapeutic activation of IL-22-producing innate lymphoid cells enhances host defenses to Clostridioides difficile infection
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    sciencedirect.com/science/article/pii/S2211124725002098
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pathway-instructed therapeutic selection of ruxolitinib reduces neuroinflammation in fungal postinfectious inflammatory syndrome
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    pmc.ncbi.nlm.nih.gov/articles/PMC11927619/
  43. www.science.org www.science.org
    Pathway-instructed therapeutic selection of ruxolitinib reduces neuroinflammation in fungal postinfectious inflammatory syndrome
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    science.org/doi/10.1126/sciadv.adi9885
  44. 52.53.155.43 52.53.155.43
    Organoid modeling reveals the tumorigenic potential of the alveolar progenitor cell state
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    52.53.155.43/1c70dafeeeda06325918fe95f6455c023d1ce5ae/March-2025-Carla-Kim-li-et-al-2025-organoid-modeling-reveals-the-tumorigenic-potential-of-the-alveolar-progenitor-cell-state-html.html
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IL-24 promotes atopic dermatitis-like inflammation through driving MRSA-induced allergic responses
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    pmc.ncbi.nlm.nih.gov/articles/PMC11892005/
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    Role of clonal inflammatory microglia in histiocytosis-associated neurodegeneration
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    sciencedirect.com/science/article/pii/S0896627325001205
  47. www.sciencedirect.com www.sciencedirect.com
    The pro-inflammatory cytokine IL6 suppresses mitochondrial function via the gp130-JAK1/STAT1/3-HIF1α/ERRα axis
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    sciencedirect.com/science/article/pii/S2211124725001743
  48. 52.53.155.43 52.53.155.43
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    Monocytes from patients with myelodysplastic syndrome inhibit natural killer cell-mediated antitumor function through the CD200/CD200R pathway
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    sciencedirect.com/science/article/pii/S1567576925003844
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    A cellular and molecular basis of leptin resistance
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    sciencedirect.com/science/article/pii/S1550413125000014
  51. Feb 2025
  52. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Taming interleukin-12: Engineering of bispecific antibody-based IL-12 mimetics with biased agonism capacities
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    onlinelibrary.wiley.com/doi/10.1002/pro.70072
  53. dx.doi.org dx.doi.org
    The roles of Growth Hormone dependent JAK-STAT5 and Lyn kinase signalling in determining lifespan and cancer incidence
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    dx.doi.org/10.1210/endocr/bqae136
  54. aacrjournals.org aacrjournals.org
    MerTK Induces Dysfunctional Dendritic Cells by Metabolic Reprogramming
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    aacrjournals.org/cancerimmunolres/article/12/9/1268/747083/MerTK-Induces-Dysfunctional-Dendritic-Cells-by
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    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17463
  56. www.sciencedirect.com www.sciencedirect.com
    Synergistic role of gut-microbial L-ornithine in enhancing ustekinumab efficacy for Crohn’s disease
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    sciencedirect.com/science/article/pii/S1550413125000075
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    GPR37L1 identifies spinal cord astrocytes and protects neuropathic pain after nerve injury
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    sciencedirect.com/science/article/pii/S0896627325000388
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SMAD4 and KRAS Status Shape Cancer Cell-Stromal Crosstalk and Therapeutic Response in Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC7617379/
  59. 52.53.155.43 52.53.155.43
    Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer’s disease through disrupted regulated intramembrane proteolysis
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    52.53.155.43/ccdd8f2b9b0076ccdaf42c273b248e5adbb5da1d/2024.09.09.611621v1.full-html.html
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    Engineered commensals for targeted nose-to-brain drug delivery
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    sciencedirect.com/science/article/pii/S0092867425000467
  61. www.sciencedirect.com www.sciencedirect.com
    Recirculating regulatory T cells mediate thymic regeneration through amphiregulin following damage
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    sciencedirect.com/science/article/pii/S1074761325000317
  62. Jan 2025
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acquired resistance to PD-L1 inhibition enhances a type I IFN-regulated secretory program in tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11772817/
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hyperleptinemia contributes to antipsychotic drug-associated obesity and metabolic disorders
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    pmc.ncbi.nlm.nih.gov/articles/PMC11755893/
  65. www.sciencedirect.com www.sciencedirect.com
    Clonally expanded, targetable, natural killer-like NKG7 T cells seed the aged spinal cord to disrupt myeloid-dependent wound healing
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    sciencedirect.com/science/article/pii/S0896627324009115
  66. www.sciencedirect.com www.sciencedirect.com
    Neutrophil extracellular traps promote pre-metastatic niche formation in the omentum by expanding innate-like B cells that express IL-10
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    sciencedirect.com/science/article/pii/S1535610824004793
  67. Dec 2024
  68. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
    Chronic sleep deprivation disturbs energy balance modulated by suprachiasmatic nucleus efferents in mice
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    bmcbiol.biomedcentral.com/articles/10.1186/s12915-024-02097-4
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Direct Effects of the Janus Kinase Inhibitor Baricitinib on Sensory Neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC11593535/
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    MAPK14/p38α shapes the molecular landscape of endometrial cancer and promotes tumorigenic characteristics
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    sciencedirect.com/science/article/pii/S2211124724014554
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    A glucocorticoid spike derails muscle repair to heterotopic ossification after spinal cord injury
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    sciencedirect.com/science/article/pii/S2666379124006207
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    Genetic and microenvironmental evolution of colorectal liver metastases under chemotherapy
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    sciencedirect.com/science/article/pii/S2666379124006098
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    Campylobacter jejuni-derived cytolethal distending toxin promotes colorectal cancer metastasis
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    sciencedirect.com/science/article/pii/S1931312824004372
  75. www.biorxiv.org www.biorxiv.org
    Epstein-Barr viral product-containing exosome facilitates LIF-associated immunosuppressive polarization of macrophage in nasopharyngeal carcinoma
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    biorxiv.org/content/10.1101/2024.11.25.625317v1
  76. Nov 2024
  77. www.biorxiv.org www.biorxiv.org
    Tumor-intrinsic LKB1-LIF signaling axis establishes a myeloid niche to promote immune evasion and tumor growth
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    biorxiv.org/content/10.1101/2023.07.15.549147v1
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deciphering the composition and key driver genes of breast invasive micropapillary carcinoma by multi-omics analysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11549989/
  79. www.sciencedirect.com www.sciencedirect.com
    Integrated multiomic analysis identifies TRIP13 as a mediator of alveolar epithelial type II cell dysfunction in idiopathic pulmonary fibrosis
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    sciencedirect.com/science/article/pii/S0925443924005660
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    β2-integrins control HIF1α activation in human neutrophils
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    pmc.ncbi.nlm.nih.gov/articles/PMC11513320/
  81. Oct 2024
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Local glycolysis supports injury-induced axonal regeneration
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    ncbi.nlm.nih.gov/pmc/articles/PMC11451009/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hydroxyproline metabolism enhances IFN-γ-induced PD-L1 expression and inhibits autophagic flux
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    ncbi.nlm.nih.gov/pmc/articles/PMC11426993/
  84. www.nature.com www.nature.com
    QSOX2 Deficiency-induced short stature, gastrointestinal dysmotility and immune dysfunction
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    nature.com/articles/s41467-024-52587-w
  85. Sep 2024
  86. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Brown adipose tissue-derived exosomes improve polycystic ovary syndrome in mice via STAT3/GPX4 signaling pathway
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202401346R
  87. www.sciencedirect.com www.sciencedirect.com
    An ILK/STAT3 pathway controls glioblastoma stem cell plasticity
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    sciencedirect.com/science/article/pii/S1534580724005318
  88. www.sciencedirect.com www.sciencedirect.com
    CXCR4 orchestrates the TOX-programmed exhausted phenotype of CD8+ T cells via JAK2/STAT3 pathway
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    sciencedirect.com/science/article/pii/S2666979X24002702
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    IL-22 resolves MASLD via enterocyte STAT3 restoration of diet-perturbed intestinal homeostasis
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    sciencedirect.com/science/article/pii/S1550413124003644
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of resistance mechanisms to small-molecule inhibition of TEAD-regulated transcription
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    ncbi.nlm.nih.gov/pmc/articles/PMC11387499/
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PDIA3 orchestrates effector T cell program by serving as a chaperone to facilitate the non-canonical nuclear import of STAT1 and PKM2
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    ncbi.nlm.nih.gov/pmc/articles/PMC11405166/
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FNIP1 suppresses colorectal cancer progression through inhibiting STAT3 phosphorylation and nuclear translocation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11389550/
  93. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mcam stabilizes a luminal progenitor-like breast cancer cell state via Ck2 control and Src/Akt/Stat3 attenuation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11401886/
  95. www.sciencedirect.com www.sciencedirect.com
    H3K9 lactylation in malignant cells facilitates CD8+ T cell dysfunction and poor immunotherapy response
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