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Generation of antigen-specific paired-chain antibodies using large language models

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1. scibot 05 Nov 2025
  
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  DOI: 10.1016/j.cell.2025.10.006
  
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sciencedirect.com/science/article/pii/S0092867425011353
Oct 2025
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Structure and function of a pair of non-competing monoclonal antibodies against Langya henipavirus attachment glycoprotein

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1. scibot 15 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116407
  
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sciencedirect.com/science/article/pii/S2211124725011787
Aug 2025
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Structurally conserved human anti-A35 antibodies protect mice and macaques from mpox virus infection

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1. scibot 27 Aug 2025
  
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  DOI: 10.1016/j.cell.2025.08.005
  
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sciencedirect.com/science/article/pii/S0092867425009195
Jul 2025
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CD4 T cell counts are inversely correlated with anti-gp120 cluster A antibodies in antiretroviral therapy-treated PLWH

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1. scibot 22 Jul 2025
  
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  DOI: 10.1016/j.ebiom.2025.105856
  
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sciencedirect.com/science/article/pii/S2352396425003007
Jun 2025
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Genetic signatures in the highly virulent subtype B human immunodeficiency virus-1 conferring resistance to broadly neutralizing antibodies

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  DOI: 10.1016/j.isci.2025.112847
  
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sciencedirect.com/science/article/pii/S2589004225011083
May 2025
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A distinctive IGHV3-66 SARS-CoV-2 neutralizing antibody elicited by primary infection with an Omicron variant

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1. scibot 19 May 2025
  
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  DOI: 10.1016/j.str.2025.04.005
  
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sciencedirect.com/science/article/pii/S096921262500139X
Dec 2024
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A multidonor class of highly glycan-dependent HIV-1 gp120-gp41 interface-targeting broadly neutralizing antibodies

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1. scibot 17 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115010
  
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sciencedirect.com/science/article/pii/S2211124724013615
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Botensilimab, an Fc-Enhanced Anti–CTLA-4 Antibody, Is Effective against Tumors Poorly Responsive to Conventional Immunotherapy

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1. scibot 11 Dec 2024
  
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  DOI: 10.1158/2159-8290.CD-24-0190
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11609826/
Jul 2024
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Membrane HIV-1 Envelope Glycoproteins Stabilized More Strongly in a Pretriggered Conformation than Natural Virus Envs

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1. scibot 10 Jul 2024
  
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sciencedirect.com/science/article/pii/S258900422401366X
Mar 2024
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Soluble ACE2 correlates with severe COVID-19 and can impair antibody responses

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1. scibot 08 Mar 2024
  
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  DOI: 10.1016/j.isci.2024.109330
  
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sciencedirect.com/science/article/pii/S2589004224005510
Feb 2024
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Long trimer-immunization interval and appropriate adjuvant reduce immune responses to the soluble HIV-1-envelope trimer base

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1. scibot 08 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.108877
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10839646/
Jul 2023
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HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide

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1. scibot 13 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112755
  
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sciencedirect.com/science/article/pii/S2211124723007660
May 2023
www.cell.com www.cell.com

Omicron BQ.1.1 and XBB.1 unprecedentedly escape broadly neutralizing antibodies elicited by prototype vaccination

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1. scibot 24 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112532
  
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2. scibot 24 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112532
  
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cell.com/cell-reports/fulltext/S2211-1247(23)00543-0
Apr 2023
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Potent anti-viral activity of a trispecific HIV antibody in SHIV-infected monkeys

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1. scibot 18 Apr 2023
  
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  DOI: 10.1016/j.celrep.2021.110199
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8767641/
Jan 2023
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Functional HIV-1/HCV cross-reactive antibodies isolated from a chronically co-infected donor

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1. scibot 28 Jan 2023
  
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  DOI: 10.1016/j.celrep.2023.112044
  
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sciencedirect.com/science/article/pii/S2211124723000554
Nov 2022
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HIV-1 Vpu restricts Fc-mediated effector functions in vivo

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1. scibot 09 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111624
  
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sciencedirect.com/science/article/pii/S2211124722014954
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A key F27I substitution within HCDR1 facilitates the rapid maturation of P2C-1F11-like neutralizing antibodies in a SARS-CoV-2-infected donor

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1. scibot 07 Sep 2022
  
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  DOI: 10.1016/j.celrep.2022.111335
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9395280/
Aug 2022
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Antibodies from primary humoral responses modulate recruitment of naive B cells during secondary responses

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1. scibot 26 Aug 2022
  
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  DOI: 10.1016/j.immuni.2022.07.020
  
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sciencedirect.com/science/article/pii/S1074761322003557
Jun 2022
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B cells expressing IgM B cell receptors of HIV-1 neutralizing antibodies discriminate antigen affinities by sensing binding association rates

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1. scibot 29 Jun 2022
  
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  DOI: 10.1016/j.celrep.2022.111021
  
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sciencedirect.com/science/article/pii/S2211124722008105
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Structural dynamics reveal isolate-specific differences at neutralization epitopes on HIV Env

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1. scibot 09 Jun 2022
  
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  DOI: 10.1016/j.isci.2022.104449
  
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sciencedirect.com/science/article/pii/S2589004222007209
Apr 2022
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Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site

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1. scibot 13 Apr 2022
  
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  DOI: 10.1016/j.str.2022.03.012
  
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sciencedirect.com/science/article/pii/S0969212622000934
Feb 2022
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Protocol to identify and monitor key mutations of broadly neutralizing antibody lineages following sequential immunization of Ig-humanized mice

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1. scibot 23 Feb 2022
  
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  DOI: 10.1016/j.xpro.2022.101180
  
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sciencedirect.com/science/article/pii/S2666166722000600
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Cryo-ET of Env on intact HIV virions reveals structural variation and positioning on the Gag lattice

2
1. scibot 11 Feb 2022
  
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  DOI: 10.1016/j.cell.2022.01.013
  
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  DOI: 10.1016/j.cell.2022.01.013
  
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sciencedirect.com/science/article/pii/S009286742200071X
Jan 2022
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PID controls: the forgotten bioprocess parameters

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1. scibot 28 Jan 2022
  
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  DOI: 10.1007/s43938-022-00008-z
  
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link.springer.com/article/10.1007/s43938-022-00008-z
Nov 2021
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Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies

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1. scibot 03 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.109922
  
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sciencedirect.com/science/article/pii/S2211124721013954
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 07 Aug 2021
  
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  DOI: 10.1016/j.celrep.2019.03.039
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6458978/
Jul 2021
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Untitled document

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1. scibot 30 Jul 2021
  
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  DOI: 10.1016/j.immuni.2018.10.015
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6303191/
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Untitled document

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  DOI: 10.1016/j.immuni.2018.10.015
  
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sciencedirect.com/science/article/pii/S1074761318304801
Jun 2021
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A diverse collection of B cells responded to HIV infection in infant BG505

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  DOI: 10.1016/j.xcrm.2021.100314
  
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sciencedirect.com/science/article/pii/S2666379121001579
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Different evolutionary pathways of HIV-1 between fetus and mother perinatal transmission pairs indicate unique immune selection in fetuses

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  DOI: 10.1016/j.xcrm.2021.100315
  
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sciencedirect.com/science/article/pii/S2666379121001580
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Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions

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1. scibot 11 Jun 2021
  
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  DOI: 10.1016/j.xcrm.2021.100313
  
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sciencedirect.com/science/article/pii/S2666379121001567
May 2021
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Mining HIV controllers for broad and functional antibodies to recognize and eliminate HIV-infected cells

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1. scibot 26 May 2021
  
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  DOI: 10.1016/j.celrep.2021.109167
  
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sciencedirect.com/science/article/pii/S221112472100509X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies

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1. scibot 12 May 2021
  
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  DOI: 10.7554/eLife.65005
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8084527/
Apr 2021
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Fusion peptide priming reduces immune responses to HIV-1 envelope trimer base

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1. scibot 07 Apr 2021
  
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  DOI: 10.1016/j.celrep.2021.108937
  
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Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike

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Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth

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Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral Response

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Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens

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Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody

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Automated Design by Structure-Based Stabilization and Consensus Repair to Achieve Prefusion-Closed Envelope Trimers in a Wide Variety of HIV Strains

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Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies

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Untitled document

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Untitled document

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Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization

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Glycan Masking Focuses Immune Responses to the HIV-1 CD4-Binding Site and Enhances Elicitation of VRC01-Class Precursor Antibodies

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Interdomain Stabilization Impairs CD4 Binding and Improves Immunogenicity of the HIV-1 Envelope Trimer

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Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop

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