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Glioblastoma stem cell growth requires DOT1L-MED23 control of enhancer accessibility

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1. scibot 06 Jul 2026
  
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  DOI: 10.1016/j.celrep.2026.117647
  
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sciencedirect.com/science/article/pii/S2211124726007254
Jul 2026
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journal.pgen.1011387.s009-html.html

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  DOI: 10.1371/journal.pgen.1011387
  
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54.241.53.176/6baf3e6a8c7a828ab95a4371c54a0422dad9c85f/journal.pgen.1011387.s009-html.html
Jun 2026
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Tracking mobilization uncovers an evolutionarily conserved mechanism in suppressing mobile genetic elements

1
1. scibot 23 Jun 2026
  
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  DOI: 10.1016/j.molcel.2026.05.022
  
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sciencedirect.com/science/article/pii/S1097276526003461
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SETDB1 and HUSH modulate Xist RNA levels during establishment of X chromosome inactivation

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1. scibot 10 Jun 2026
  
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  DOI: 10.1038/s41467-026-71569-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13243529/
Apr 2026
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TORC1-dependent translation drives chromatin remodeling during the germ-cell-to-maternal transition in Drosophila

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1. scibot 01 Apr 2026
  
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  DOI: 10.1038/s44318-026-00697-0
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12953698/
Mar 2026
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Multi-omic analyses reveal a differential contribution of chromatin-associated PP1 holoenzymes to mitotic exit and G1 re-establishment

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1. scibot 20 Mar 2026
  
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  DOI: 10.1016/j.devcel.2026.02.016
  
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A feedback loop between heterochromatin and the nucleopore complex controls germ-cell to oocyte transition during Drosophila oogenesis

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1. scibot 13 Mar 2026
  
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  DOI: 10.1016/j.devcel.2023.08.014
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11301765/
Feb 2026
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Minimizing far-extending chromatin perturbation in genome editing preserves stem cell identity

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1. scibot 26 Feb 2026
  
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  DOI: 10.1016/j.stem.2026.01.015
  
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sciencedirect.com/science/article/pii/S193459092600038X
Dec 2025
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DROSHA, DICER, and damage-induced long ncRNA control BMI1-dependent transcriptional repression at DNA double-strand break

1
1. scibot 13 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116605
  
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sciencedirect.com:5037/science/article/pii/S2211124725013774
Nov 2025
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CUT&Tag overcomes biases of ChIP and establishes chromatin patterns for repetitive genomic loci

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1. scibot 19 Nov 2025
  
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  DOI: 10.1016/j.isci.2025.113757
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12605858/
Oct 2025
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N6-methyladenosine on L1PA governs the trans-silencing of LTRs and restrains totipotency in naive human embryonic stem cells

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1. scibot 30 Oct 2025
  
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  DOI: 10.1016/j.stem.2025.10.003
  
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sciencedirect.com/science/article/pii/S1934590925003716
Sep 2025
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Cancer cells subvert the primate-specific KRAB zinc finger protein ZNF93 to control APOBEC3B

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1. scibot 06 Sep 2025
  
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  DOI: 10.1073/pnas.2505021122
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12403153/
Aug 2025
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Composite transposons with bivalent histone marks function as RNA-dependent enhancers in cell fate regulation

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1. scibot 07 Aug 2025
  
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  DOI: 10.1016/j.cell.2025.07.014
  
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sciencedirect.com/science/article/pii/S0092867425008037
Jul 2025
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Multi-omics analysis reveals single-cell meiotic hotspot dynamics and epigenomic regulations in female mammals

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1. scibot 30 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116082
  
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sciencedirect.com/science/article/pii/S2211124725008538
May 2025
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KDM3A and KDM3B regulate alternative splicing in mouse pluripotent stem cells

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1. scibot 29 May 2025
  
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  DOI: 10.1016/j.isci.2025.112612
  
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sciencedirect.com/science/article/pii/S2589004225008739
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TORC1-driven translation of Nucleoporin44A promotes chromatin remodeling and germ cell-to-maternal transition in Drosophila

1
1. scibot 20 May 2025
  
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  AB_2532132
  
  DOI: 10.1101/2025.03.14.643309
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11952567/
Feb 2025
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KMT2C/KMT2D-dependent H3K4me1 mediates changes in DNA replication timing and origin activity during a cell fate transition

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1. scibot 06 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115272
  
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sciencedirect.com/science/article/pii/S2211124725000439
Dec 2024
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DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states

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1. scibot 05 Dec 2024
  
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  DOI: 10.1016/j.molcel.2024.11.009
  
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sciencedirect.com/science/article/pii/S1097276524009146
Oct 2024
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The chromodomain protein CDYL confers forebrain identity to human cortical organoids by inhibiting neuronatin

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1. scibot 09 Oct 2024
  
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  DOI: 10.1016/j.celrep.2024.114814
  
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2. scibot 09 Oct 2024
  
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  DOI: 10.1016/j.celrep.2024.114814
  
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sciencedirect.com/science/article/pii/S2211124724011653
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Multiplexed chromatin immunoprecipitation sequencing for quantitative study of histone modifications and chromatin factors

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1. scibot 08 Oct 2024
  
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  DOI: 10.1038/s41596-024-01058-z
  
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link.springer.com/article/10.1038/s41596-024-01058-z
Sep 2024
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Clusters of lineage-specific genes are anchored by ZNF274 in repressive perinucleolar compartments

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1. scibot 27 Sep 2024
  
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  DOI: 10.1126/sciadv.ado1662
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11397430/
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Nuclear actin is a critical regulator of Drosophila female germline stem cell maintenance

1
1. scibot 18 Sep 2024
  
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  DOI: 10.1101/2024.08.27.609996
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11383290/
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Promoter DNA methylation and transcription factor condensation are linked to transcriptional memory in mammalian cells

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1. scibot 10 Sep 2024
  
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  DOI: 10.1016/j.cels.2024.08.007
  
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sciencedirect.com/science/article/pii/S2405471224002370
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GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant

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1. scibot 04 Sep 2024
  
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  DOI: 10.1016/j.ccell.2024.08.006
  
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sciencedirect.com/science/article/pii/S1535610824003052
Aug 2024
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Mapping the dynamics of epigenetic adaptation in S. pombe during heterochromatin misregulation

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1. scibot 18 Aug 2024
  
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  DOI: 10.1016/j.devcel.2024.07.006
  
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Mrc1 regulates parental histone segregation and heterochromatin inheritance

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  DOI: 10.1016/j.molcel.2024.07.002
  
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sciencedirect.com/science/article/pii/S1097276524005732
Jul 2024
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CircARAP2 controls sMICA-induced NK cell desensitization by erasing CTCF/PRC2-induced suppression in early endosome marker RAB5A

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1. scibot 30 Jul 2024
  
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  DOI: 10.1007/s00018-024-05285-1
  
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link.springer.com/article/10.1007/s00018-024-05285-1
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TULIPs decorate the three-dimensional genome of PFA ependymoma

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1. scibot 12 Jul 2024
  
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  DOI: 10.1016/j.cell.2024.06.023
  
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2. scibot 11 Jul 2024
  
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  DOI: 10.1016/j.cell.2024.06.023
  
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cell.com/cell/abstract/S0092-8674(24)00697-4
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Genome organization regulates nuclear pore complex formation and promotes differentiation during Drosophila oogenesis

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1. scibot 09 Jul 2024
  
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  DOI: 10.1101/gad.351402.123
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11216175/
May 2024
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An unscheduled switch to endocycles induces a reversible senescent arrest that impairs growth of the Drosophila wing disc

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1. scibot 29 May 2024
  
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  DOI: 10.1101/2024.03.14.585098
  
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  DOI: 10.1101/2024.03.14.585098
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10980049/
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Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration

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1. scibot 03 May 2024
  
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  DOI: 10.1016/j.cell.2024.04.005
  
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sciencedirect.com/science/article/pii/S0092867424004008
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MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons

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1. scibot 02 May 2024
  
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  DOI: 10.1016/j.neuron.2024.04.007
  
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sciencedirect.com/science/article/pii/S0896627324002459
Mar 2024
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Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma

2
1. scibot 29 Mar 2024
  
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  DOI: 10.1016/j.xcrm.2024.101468
  
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A Cluster of Evolutionarily Recent KRAB Zinc Finger Proteins Protects Cancer Cells from Replicative Stress-Induced Inflammation

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DNMT3B PWWP mutations cause hypermethylation of heterochromatin

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Enhancer-promoter interactions are reconfigured through the formation of long-range multiway hubs as mouse ES cells exit pluripotency

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MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors

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Genome organization regulates nuclear pore complex formation and promotes differentiation during Drosophila oogenesis

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RNA mis-splicing drives viral mimicry response after DNMTi therapy in SETD2-mutant kidney cancer

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Loss of epigenetic information as a cause of mammalian aging

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Functional partitioning of transcriptional regulators by patterned charge blocks

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Methionine metabolism controls the B cell EBV epigenome and viral latency

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SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression

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Stage-specific H3K9me3 occupancy ensures retrotransposon silencing in human pre-implantation embryos

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MYC and MIZ1-dependent vesicular transport of double-strand RNA controls immune evasion in pancreatic ductal adenocarcinoma

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Distal and proximal cis-regulatory elements sense X chromosome dosage and developmental state at the Xist locus

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Ago1 controls myogenic differentiation by regulating eRNA-mediated CBP-guided epigenome reprogramming

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Maternally inherited piRNAs direct transient heterochromatin formation at active transposons during early Drosophila embryogenesis

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A Robust Transposon-Endogenizing Response from Germline Stem Cells

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The Drosophila speciation factor HMR localizes to genomic insulator sites

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Suv4-20h2 protects against influenza virus infection by suppression of chromatin loop formation

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A spontaneous genetically induced epiallele at a retrotransposon shapes host genome function

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Dux-Mediated Corrections of Aberrant H3K9ac during 2-Cell Genome Activation Optimize Efficiency of Somatic Cell Nuclear Transfer

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Dimerisation of the PICTS complex via LC8/Cut-up drives co-transcriptional transposon silencing in Drosophila

1
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The INO80 Complex Regulates Epigenetic Inheritance of Heterochromatin

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Large domains of heterochromatin direct the formation of short mitotic chromosome loops

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KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage

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Nucleome Dynamics during Retinal Development

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Epigenetic Compensation Promotes Liver Regeneration

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Broad Heterochromatic Domains Open in Gonocyte Development Prior to De Novo DNA Methylation

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  DOI: 10.1016/j.devcel.2019.07.023
  
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Untitled document

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Untitled document

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  DOI: 10.1016/j.molcel.2019.02.009
  
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sciencedirect.com/science/article/pii/S1097276519300991
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Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses

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Lineage-Determining Transcription Factor TCF-1 Initiates the Epigenetic Identity of T Cells

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Nov 2017
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FXR1 regulates transcription and is required for growth of human cancer cells with TP53/FXR2 homozygous deletion

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LTR-Retrotransposon Control by tRNA-Derived Small RNAs

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The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis

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