Hypothesis

8 Matching Annotations

Last 7 days
www.biorxiv.org www.biorxiv.org

Autophagy activators normalize aberrant Tau proteostasis and rescue synapses in human familial Alzheimer’s disease iPSC-derived cortical organoids

1
1. scibot 09 Apr 2026
  
  in Public
  
  phospho-Tau pT181
  
  DOI: 10.1101/2025.06.25.661453
  
  Resource: (Thermo Fisher Scientific Cat# 701530, RRID:AB_2532491)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:AB_2532491
  
  What is this?
  
  RRID:AB_2532491
Visit annotations in context

Tags

RRID:AB_2532491

Annotators

scibot

URL

biorxiv.org/content/10.1101/2025.06.25.661453v2
Feb 2026
www.sciencedirect.com www.sciencedirect.com

Neuronal PPP2R5C in plasma is a potential biomarker for early diagnosis of Alzheimer’s disease

1
1. scibot 20 Feb 2026
  
  in Public
  
  RRID:AB_2532491
  
  DOI: 10.1016/j.xcrm.2026.102631
  
  Resource: (Thermo Fisher Scientific Cat# 701530, RRID:AB_2532491)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2532491
  
  What is this?
  
  RRID:AB_2532491
Visit annotations in context

Tags

RRID:AB_2532491

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379126000480
Sep 2025
www.sciencedirect.com www.sciencedirect.com

Biomarker-related phospho-tau217 appears in synapses around Aβ plaques prior to tau tangle in cerebral cortex of preclinical Alzheimer’s disease

1
1. scibot 03 Sep 2025
  
  in Public
  
  RRID:AB_2532491
  
  DOI: 10.1016/j.celrep.2025.116203
  
  Resource: (Thermo Fisher Scientific Cat# 701530, RRID:AB_2532491)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2532491
  
  What is this?
  
  RRID:AB_2532491
Visit annotations in context

Tags

RRID:AB_2532491

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112472500974X
May 2025
www.sciencedirect.com www.sciencedirect.com

Differential roles of human tau isoforms in the modulation of inflammation and development of neuropathology

1
1. scibot 18 May 2025
  
  in Public
  
  RRID:AB_2532491
  
  DOI: 10.1016/j.nbd.2025.106942
  
  Resource: (Thermo Fisher Scientific Cat# 701530, RRID:AB_2532491)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2532491
  
  What is this?
  
  RRID:AB_2532491
Visit annotations in context

Tags

RRID:AB_2532491

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0969996125001585
Jun 2022
www.sciencedirect.com www.sciencedirect.com

Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration

1
1. scibot 17 Jun 2022
  
  in Public
  
  RRID:AB_2532491
  
  DOI: 10.1016/j.isci.2022.104519
  
  Resource: (Thermo Fisher Scientific Cat# 701530, RRID:AB_2532491)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2532491
  
  What is this?
  
  RRID:AB_2532491
Visit annotations in context

Tags

RRID:AB_2532491

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004222007908
May 2022
www.sciencedirect.com www.sciencedirect.com

Nde1 is required for heterochromatin compaction and stability in neocortical neurons

1
1. scibot 19 May 2022
  
  in Public
  
  RRID:AB_2532491
  
  DOI: 10.1016/j.isci.2022.104354
  
  Resource: (Thermo Fisher Scientific Cat# 701530, RRID:AB_2532491)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2532491
  
  What is this?
  
  RRID:AB_2532491
Visit annotations in context

Tags

RRID:AB_2532491

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004222006253
Jun 2021
www.jneurosci.org www.jneurosci.org

Cereblon regulates the proteotoxicity of tau by tuning the chaperone activity of DNAJA1

1
1. scibot 29 Jun 2021
  
  in Public
  
  RRID:AB_2532491
  
  DOI: 10.1523/JNEUROSCI.2494-20.2021
  
  Resource: (Thermo Fisher Scientific Cat# 701530, RRID:AB_2532491)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2532491
  
  What is this?
  
  RRID:AB_2532491
Visit annotations in context

Tags

RRID:AB_2532491

Annotators

scibot

URL

jneurosci.org/content/41/24/5138
Jan 2020
www.sciencedirect.com www.sciencedirect.com

IMM-H004 reduced okadaic acid-induced neurotoxicity by inhibiting Tau pathology in vitro and in vivo

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2532491
  
  DOI: 10.1016/j.neuro.2019.09.012
  
  Resource: (Thermo Fisher Scientific Cat# 701530, RRID:AB_2532491)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2532491
  
  What is this?
  
  RRID:AB_2532491 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_2532491

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0161813X19301020