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Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy

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  DOI: 10.1016/j.cell.2026.02.008
  
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sciencedirect.com/science/article/pii/S009286742600173X
Feb 2026
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Anti-IL-15 treatment reduces acute lentivirus inflammation and signaling in the brain

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sciencedirect.com/science/article/pii/S2666379125006408
Jan 2026
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Advanced human organoid-on-chip with physiological cellular complexity reveals bidirectional secretion patterns

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pmc.ncbi.nlm.nih.gov/articles/PMC12829128/
Jun 2025
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In Vitro Comparison of Two Python‐Based Programs for the Automated Analysis of Tight‐Junction Phenotype in Brain Endothelium During Bacterial Infection

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1. scibot 18 Jun 2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12169080/
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Breaking Barriers: A Protocol to Investigate Intestinal Pathogen Adhesion, Invasion, and Translocation Through In Vitro, In Vivo, and Imaging Technologies

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  DOI: 10.1007/978-1-0716-4627-4_1
  
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link.springer.com/protocol/10.1007/978-1-0716-4627-4_1
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Deficiency in N-cadherin-Akt3 signaling impairs the blood-brain barrier

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cell.com/cell-reports/fulltext/S2211-1247(25)00602-3
Apr 2025
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ARHGAP12 suppresses F-actin assembly to control epithelial tight junction mechanics and paracellular leak pathway permeability

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sciencedirect.com/science/article/pii/S2211124725002827
Mar 2025
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SSAO-mediated decrease of endothelial BDNF release affects neuronal GluA1 and PSD95 expression: a peripheral mechanism inducing NVU and CNS disturbances

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biorxiv.org/content/10.1101/2025.03.04.641410v1
Dec 2024
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Self-organization of the hematopoietic vascular niche and emergent innate immunity on a chip

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sciencedirect.com/science/article/pii/S1934590924004028
Sep 2024
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A living organoid biobank of patients with Crohn’s disease reveals molecular subtypes for personalized therapeutics

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sciencedirect.com/science/article/pii/S2666379124004786
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o-guinn-et-al-2024-fxr-deletion-attenuates-intestinal-barrier-dysfunction-in-murine-acute-intestinal-inflammation-html.html

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1. scibot 06 Sep 2024
  
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  RRID:AB_2533101 DOI:10.1152/ajpgi.00063.2024
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52.53.155.43/38c001291b888dcf9d96e78ed9f3c0ee31989d96/o-guinn-et-al-2024-fxr-deletion-attenuates-intestinal-barrier-dysfunction-in-murine-acute-intestinal-inflammation-html.html
Aug 2024
jneuroinflammation.biomedcentral.com jneuroinflammation.biomedcentral.com

High-fat diet impairs duodenal barrier function and elicits glia-dependent changes along the gut-brain axis that are required for anxiogenic and depressive-like behaviors

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1. scibot 02 Aug 2024
  
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jneuroinflammation.biomedcentral.com/article/10.1186/s12974-021-02164-5/tables/2
May 2024
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Modeling blood-brain barrier formation and cerebral cavernous malformations in human PSC-derived organoids

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sciencedirect.com/science/article/pii/S1934590924001462
Mar 2024
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CRB1-associated retinal degeneration is dependent on bacterial translocation from the gut

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  DOI: 10.1016/j.cell.2024.01.040
  
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sciencedirect.com/science/article/pii/S0092867424001089
Feb 2024
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CRB1-associated retinal degeneration is dependent on bacterial translocation from the gut

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  DOI: 10.1016/j.cell.2024.01.040
  
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sciencedirect.com/science/article/pii/S0092867424001089
Nov 2023
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Structured wound angiogenesis instructs mesenchymal barrier compartments in the regenerating nerve

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1. scibot 18 Nov 2023
  
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  DOI: 10.1016/j.neuron.2023.10.025
  
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sciencedirect.com/science/article/pii/S0896627323008061
Jun 2023
academic.oup.com academic.oup.com

Cadmium-induced Sertoli cell injury through p38-MAPK and related signaling proteins – a study by RNA sequencing

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1. scibot 02 Jun 2023
  
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  DOI: 10.1210/endocr/bqad045
  
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academic.oup.com/endo/article/164/6/bqad045/7079002
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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  DOI: 10.1111/bph.16065
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16065
Dec 2022
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Molecular Indicators of Blood-Brain Barrier Breakdown and Neuronal Injury in Pregnancy Complicated by Fetal Growth Restriction

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  DOI: 10.3390/ijms232213798
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9695431/
Sep 2022
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An in vitro model of glucose transporter 1 deficiency syndrome at the blood-brain barrier using induced pluripotent stem cells

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  DOI: 10.1111/jnc.15684
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15684
Aug 2022
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FYN regulates cell adhesion at the blood-testis barrier and the apical ectoplasmic specialization via its effect on Arp3 in the mouse testis

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ncbi.nlm.nih.gov/pmc/articles/PMC9396411/
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A microengineered Brain-Chip to model neuroinflammation in humans

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sciencedirect.com/science/article/pii/S2589004222010859
Jun 2022
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Cholesterol and matrisome pathways dysregulated in astrocytes and microglia

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  DOI: 10.1016/j.cell.2022.05.017
  
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sciencedirect.com/science/article/pii/S0092867422006481
Mar 2022
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Urolithin A alleviates blood-brain barrier disruption and... : Neural Regeneration Research

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  DOI: 10.4103/1673-5374.335163
  
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journals.lww.com/nrronline/Fulltext/2022/17090/Urolithin_A_alleviates_blood_brain_barrier.32.aspx
Jan 2022
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BPS Publications

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  DOI: 10.1111/bph.15739
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15739
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Abeta Peptides Disrupt the Barrier Integrity and Glucose Metabolism of Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells

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sciencedirect.com/science/article/pii/S0161813X22000158
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Blood-brain barrier-restricted translocation of Toxoplasma gondii from cortical capillaries

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  DOI: 10.7554/eLife.69182
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8700292/
Nov 2021
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Identification of a gut microbiota member that ameliorates DSS-induced colitis in intestinal barrier enhanced Dusp6-deficient mice

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  DOI: 10.1016/j.celrep.2021.110016
  
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sciencedirect.com/science/article/pii/S2211124721014984
pubs.rsc.org pubs.rsc.org

Dihydroquercetin supplement alleviates colonic inflammation potentially through improved gut microbiota community in mice

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  DOI: 10.1039/D1FO01422F
  
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pubs.rsc.org/en/content/articlehtml/2021/fo/d1fo01422f
Oct 2021
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PerfuPul—A Versatile Perfusable Platform to Assess Permeability and Barrier Function of Air Exposed Pulmonary Epithelia

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  DOI: 10.3389/fbioe.2021.743236
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8526933/
Sep 2021
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Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19

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  DOI: 10.7554/eLife.66417
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8463074/
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Synthetic VSMCs induce BBB disruption mediated by MYPT1 in ischemic stroke

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  DOI: 10.1016/j.isci.2021.103047
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8441154/
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Tumor-induced disruption of the blood-brain barrier promotes host death

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  DOI: 10.1016/j.devcel.2021.08.010
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8511098/
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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  DOI: 10.1016/j.ebiom.2017.12.011
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5828370/
Jul 2021
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Untitled document

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  RRID:AB_2533101
  
  DOI: 10.1016/j.ebiom.2017.12.011
  
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ebiomedicine.com/article/S2352-3964(17)30492-9/abstract
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Human iPSC-Derived Blood-Brain Barrier Chips Enable Disease Modeling and Personalized Medicine Applications

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1. scibot 28 Jul 2021
  
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  RRID: AB_2533101
  
  DOI: 10.1016/j.stem.2019.05.011
  
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sciencedirect.com/science/article/pii/S1934590919302152
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  DOI: 10.1016/j.celrep.2018.10.097
  
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sciencedirect.com/science/article/pii/S2211124718317182
Jun 2021
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Neonatal susceptibility to meningitis results from the immaturity of epithelial barriers and gut microbiota

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  RRID:AB_2533101
  
  DOI: 10.1016/j.celrep.2021.109319
  
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sciencedirect.com/science/article/pii/S2211124721006951
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Interleukin-22 signaling attenuates necrotizing enterocolitis by promoting epithelial cell regeneration

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  RRID:AB_2533101
  
  DOI: 10.1016/j.xcrm.2021.100320
  
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sciencedirect.com/science/article/pii/S2666379121001634
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Desmosomes polarize and integrate chemical and mechanical signaling to govern epidermal tissue form and function

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  DOI: 10.1016/j.cub.2021.05.021
  
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sciencedirect.com/science/article/pii/S0960982221006801
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Differentiation of human pluripotent stem cells to brain microvascular endothelial cell-like cells suitable to study immune cell interactions

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  33-1500
  
  DOI: 10.1016/j.xpro.2021.100563
  
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sciencedirect.com/science/article/pii/S2666166721002707
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The Mammalian Crumbs Complex Defines a Distinct Polarity Domain Apical of Epithelial Tight Junctions

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  DOI: 10.1016/j.cub.2020.05.032
  
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sciencedirect.com/science/article/pii/S0960982220306710
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Presence of a mutation in PSEN1 or PSEN2 gene is associated with an impaired brain endothelial cell phenotype in vitro

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  AB_2533101
  
  DOI: 10.1186/s12987-020-00235-y
  
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link.springer.com/article/10.1186/s12987-020-00235-y
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A Novel Tri‐culture Model for Neuroinflammation

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  DOI: 10.1111/jnc.15171
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15171
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ALS-causing SOD1 mutants regulate occludin phosphorylation/ubiquitination and endocytic trafficking via the ITCH/Eps15/Rab5 axis

1
1. scibot 25 Feb 2021
  
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  occludin
  
  DOI: 10.1016/j.nbd.2021.105315
  
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sciencedirect.com/science/article/pii/S0969996121000644
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Downregulation of uPAR promotes urokinase translocation into the nucleus and epithelial to mesenchymal transition in neuroblastoma

1
1. scibot 24 Feb 2021
  
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  RRID:AB_2533101
  
  DOI: 10.1002/jcp.29555
  
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onlinelibrary.wiley.com/doi/10.1002/jcp.29555
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Neurolysin substrates bradykinin, neurotensin and substance P enhance brain microvascular permeability in a human in vitro model

1
1. scibot 09 Feb 2021
  
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  AB_2533101
  
  DOI: 10.1111/jne.12931
  
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onlinelibrary.wiley.com/doi/full/10.1111/jne.12931
Dec 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Association of Hyperuricemia With Immune Disorders and Intestinal Barrier Dysfunction

1
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  RRID:AB_2533101
  
  DOI: 10.3389/fphys.2020.524236
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7729003/
Oct 2020
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Uric acid drives intestinal barrier dysfunction through TSPO-mediated NLRP3 inflammasome activation

1
1. scibot 27 Oct 2020
  
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  RRID:AB_2533101
  
  DOI: 10.1007/s00011-020-01409-y
  
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link.springer.com/article/10.1007/s00011-020-01409-y
Sep 2020
www.jci.org www.jci.org

Inactivation of paracellular cation-selective claudin-2 channels attenuates immune-mediated experimental colitis in mice

1
1. scibot 17 Sep 2020
  
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  RRID:AB_2533101
  
  DOI: 10.1172/JCI138697
  
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jci.org/articles/view/138697
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Herpes Simplex Virus 1-Induced Blood-Brain Barrier Damage Involves Apoptosis Associated With GM130-Mediated Golgi Stress

1
1. scibot 17 Sep 2020
  
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  RRID:AB_2533101
  
  DOI: 10.3389/fnmol.2020.00002
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6992570/
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Interplay between Extracellular Matrix Stiffness and JAM-A Regulates Mechanical Load on ZO-1 and Tight Junction Assembly

1
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  DOI: 10.1016/j.celrep.2020.107924
  
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sciencedirect.com/science/article/pii/S2211124720309050
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microRNA‐9‐5p alleviates blood‐brain barrier damage and neuroinflammation after traumatic brain injury

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1. scibot 03 Sep 2020
  
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  DOI: 10.1111/jnc.14963
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.14963
Aug 2020
onlinelibrary.wiley.com onlinelibrary.wiley.com

Transplantation of iPS‐derived vascular endothelial cells improves white matter ischemic damage

1
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  DOI: 10.1111/jnc.14949
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.14949
Jan 2020
www.cell.com www.cell.com

Roseburia Spp. Abundance Associates with Alcohol Consumption in Humans and Its Administration Ameliorates Alcoholic Fatty Liver in Mice

1
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  RRID:AB_2533101
  
  DOI: 10.1016/j.chom.2019.11.001
  
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cell.com/cell-host-microbe/fulltext/S1931-3128(19)30583-9
elifesciences.org elifesciences.org

Low wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice

1
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  DOI: 10.7554/eLife.43818
  
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elifesciences.org/articles/43818
Nov 2018
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Single Particle Imaging of Polarized Hepatoma Organoids upon Hepatitis C Virus Infection Reveals an Ordered and Sequential Entry Process

1
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HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model

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sciencedirect.com/science/article/pii/S2352396417304929