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Lymphatic constraint of germinal centers optimizes protective antibody responses

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1. scibot 10 Oct 2026
  
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  DOI: 10.1016/j.immuni.2026.09.013
  
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sciencedirect.com/science/article/pii/S1074761326003882
Oct 2026
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ATM safeguards DNA replication by restraining pathological repriming at endogenous base lesions

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1. scibot 01 Oct 2026
  
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  DOI: 10.1016/j.molcel.2026.09.006
  
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sciencedirect.com/science/article/pii/S109727652600626X
Sep 2026
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A scalable, high-throughput glue perturbation screening platform for molecular glue discovery

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1. scibot 24 Sep 2026
  
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  DOI: 10.1016/j.isci.2026.117600
  
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sciencedirect.com/science/article/pii/S2589004226029792
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Role of estrogen-related receptor alpha in osteogenic differentiation

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1. scibot 12 Sep 2026
  
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  DOI: 10.1007/s13577-026-01449-2
  
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link.springer.com/article/10.1007/s13577-026-01449-2
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Long-term stability of the GMP-compliant recombinant BCG vaccine against human RSV under quality control analyses

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1. scibot 11 Sep 2026
  
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  DOI: 10.1016/j.isci.2026.117131
  
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sciencedirect.com/science/article/pii/S2589004226025095
Aug 2026
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An inherited hypomorphic variant in PIEZO2 reveals structural features of mechanotransduction

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1. scibot 27 Aug 2026
  
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  DOI: 10.1016/j.neuron.2026.07.030
  
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sciencedirect.com/science/article/pii/S0896627326005854
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Brain perivascular macrophages regulate endothelial cell function via a cMAF-dependent transcriptional program in mouse and human

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1. scibot 16 Aug 2026
  
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  DOI: 10.1016/j.cell.2026.07.043
  
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sciencedirect.com/science/article/pii/S0092867426008755
May 2026
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ACSS2-mediated MYH9 crotonylation drives Zika virus-induced vascular smooth muscle cell phenotypic switching

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1. scibot 30 May 2026
  
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  DOI: 10.1016/j.celrep.2026.117465
  
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sciencedirect.com/science/article/pii/S2211124726005437
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RNA length and receptor usage define innate immune recognition across species

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1. scibot 28 May 2026
  
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  DOI: 10.64898/2026.05.21.726451
  
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biorxiv.org/content/10.64898/2026.05.21.726451v1
www-cell-com.eproxy.lib.hku.hk www-cell-com.eproxy.lib.hku.hk

Whole-genome doubling drives immune evasion by silencing antigen presentation

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1. scibot 08 May 2026
  
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  DOI: 10.1016/j.ccell.2026.04.007
  
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www-cell-com.eproxy.lib.hku.hk/cancer-cell/fulltext/S1535-6108(26)00218-7
Apr 2026
54.241.53.176 54.241.53.176

2026.03.16.711194.full-html.html

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1. scibot 02 Apr 2026
  
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  DOI: 10.64898/2026.03.16.711194
  
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54.241.53.176/ddd0edef2534ff214426a1e86f16bffcf350fe46/2026.03.16.711194.full-html.html
Mar 2026
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Disturbed mitochondrial maturation in cardiolipin remodeling-deficient cardiomyocytes

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1. scibot 10 Mar 2026
  
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  DOI: 10.1016/j.isci.2026.115111
  
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sciencedirect.com/science/article/pii/S2589004226004864
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Legionella employs the multimodal ubiquitination of Sec22b to modulate SNARE pairing

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1. scibot 11 Feb 2026
  
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  RRID:AB_2533947
  
  DOI: 10.1016/j.isci.2025.114341
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12884507/
Jan 2026
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A guide to selecting high-performing antibodies for GCase (UniProt ID: P04062) for use in western blot, immunoprecipitation, and immunofluorescence

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1. scibot 23 Jan 2026
  
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  AB_2533947
  
  DOI: 10.12688/f1000research.174230.1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12800601/
54.241.53.176 54.241.53.176

2026.01.09.698661v1.full-html.html

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1. scibot 13 Jan 2026
  
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  DOI: 10.64898/2026.01.09.698661
  
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54.241.53.176/229f150d292937106a4e15fcfbf1923f59503af0/2026.01.09.698661v1.full-html.html
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p57 increases immunotherapy efficacy by promoting cGAS-STING-mediated innate sensing in hepatocellular carcinoma

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1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116769
  
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sciencedirect.com/science/article/pii/S2211124725015414
Dec 2025
54.241.53.176 54.241.53.176

A K27-linked Ubiquitin Checkpoint Controls NOTCH Homeostasis

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1. scibot 23 Dec 2025
  
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  RRID:AB_2533947
  
  DOI: 10.64898/2025.12.18.695023
  
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54.241.53.176/4017c0bf441a0c93b25bb7d3207bac083a93d59a/2025.12.18.695023v1.full-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A guide to selecting high-performing antibodies for Heterogeneous nuclear ribonucleoproteins A2/B1(hnRNP A2/B1) (UniProt ID: P22626) for use in western blot, immunoprecipitation, and immunofluorescence

1
1. scibot 05 Dec 2025
  
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  AB_2533947
  
  DOI: 10.12688/f1000research.170886.1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12669976/
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Oxytocin treatment reduces cancer cachexia in a pre-clinical model

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1. scibot 04 Dec 2025
  
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  DOI: 10.1016/j.biopha.2025.118825
  
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sciencedirect.com:5037/science/article/pii/S0753332225010194
Oct 2025
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A guide to selecting high-performing antibodies for VCP (UniProt ID: P55072) for use in western blot, immunoprecipitation, and immunofluorescence

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1. scibot 25 Oct 2025
  
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  AB_2533947
  
  DOI: 10.12688/f1000research.169502.1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12547379/
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Limited activation interdependence and differing patterns of the in vivo effects of IKK1 and IKK2 downstream of NIK

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1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116404
  
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sciencedirect.com/science/article/pii/S2211124725011751
Sep 2025
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Safe immunosuppression-resistant pan-cancer immunotherapeutics by velcro-like density-dependent targeting of tumor-associated carbohydrate antigens

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1. scibot 27 Sep 2025
  
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  DOI: 10.1016/j.cell.2025.09.001
  
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52.53.155.43 52.53.155.43

2025.08.28.672006v1.full-html.html

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1. scibot 03 Sep 2025
  
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  RRID:AB_2533947
  
  DOI: 10.1101/2025.08.28.672006
  
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52.53.155.43/1c78deaa12ef1065bee04217bb87fcbf90d61c87/2025.08.28.672006v1.full-html.html
Aug 2025
onlinelibrary.wiley.com onlinelibrary.wiley.com

The absence of IL17A favours cytotoxic cell function and improves antigen-specific immunotherapies in pancreatic adenocarcinoma

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1. scibot 21 Aug 2025
  
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  DOI: 10.1002/ctm2.70442
  
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onlinelibrary.wiley.com/doi/10.1002/ctm2.70442
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41467_2025_56346_MOESM1_ESM-html.html

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1. scibot 15 Aug 2025
  
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  AB_2533947
  
  DOI: 10.1038/s41467-025-56346-3
  
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52.53.155.43/0cdd1395338fbad58a2c837457ae32b83153d0d5/41467_2025_56346_MOESM1_ESM-html.html
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Androgen receptor–mediated assisted loading of the glucocorticoid receptor modulates transcriptional responses in prostate cancer cells

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1. scibot 05 Aug 2025
  
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  RRID:AB_2533947
  
  DOI: 10.1101/gr.280224.124
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12315708/
Jul 2025
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High PER1 expression is associated with STK11 mutation and clinical biomarkers of immunotherapy resistance in lung adenocarcinoma

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1. scibot 29 Jul 2025
  
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  DOI: 10.1007/s00432-025-06269-9
  
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link.springer.com/article/10.1007/s00432-025-06269-9
52.53.155.43 52.53.155.43

41467_2025_56346_MOESM1_ESM (1)-html.html

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1. scibot 19 Jul 2025
  
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  DOI: 10.1038/s41467-025-56346-3
  
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52.53.155.43/1761484a67730362675820c7685649e27bb2d182/41467_2025_56346_MOESM1_ESM (1)-html.html
Jun 2025
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Conformational dynamics of a histidine molecular switch in a cation/proton antiporter

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  DOI: 10.1016/j.bbabio.2025.149563
  
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sciencedirect.com/science/article/pii/S0005272825000295
May 2025
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PDF-html.html

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  DOI: 10.1210/jendso/bvaf097
  
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52.53.155.43/aebe30c09b7d7ea93f09928e25b9120d82e96eb9/PDF-html.html
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High-resolution transcriptional impact of AIRE: effects of pathogenic variants p.Arg257Ter, p.Cys311Tyr, and polygenic risk variant p.Arg471Cys

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1. scibot 21 May 2025
  
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  DOI: 10.3389/fimmu.2025.1572789
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12053179/
Apr 2025
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Effective recognition of double-stranded RNA does not require activation of cellular inflammation

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1. scibot 16 Apr 2025
  
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  DOI: 10.1126/sciadv.ads6498
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11980852/
Dec 2024
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 29 Dec 2024
  
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  DOI: 10.1101/2024.12.20.629634
  
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52.53.155.43/8a7c3f6b8aff86a064d8132c6cfc5572d2ac9598/PDF-html.html
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Probiotics-sensing mechanism in neurons that initiates gut mitochondrial surveillance for pathogen defense

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115021
  
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sciencedirect.com/science/article/pii/S221112472401372X
Nov 2024
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Calcium-dependent regulation of neuronal excitability is rescued in Fragile X Syndrome by a tat-conjugated N-terminal fragment of FMRP

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Peptidoglycan-Chi3l1 interaction shapes gut microbiota in intestinal mucus layer

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Sep 2024
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BRAF-induced EHF Expression Affects TERT in Aggressive Papillary Thyroid Cancer

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Functional characterization of the SDR42E1 reveals its role in vitamin D biosynthesis

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Generation of a ZEB2 deficient human iPSC line (KICRi002A-4)

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Characterization of a lipid-based jumbo phage compartment as a hub for early phage infection

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May 2024
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Extracellular matrix stiffness mediates insulin secretion in pancreatic islets via mechanosensitive Piezo1 channel regulated Ca2+ dynamics

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Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation

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JNEUROSCI.0136-24.2024.full-html.html

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Apr 2024
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The early-stage clinical course of anti-pituitary-specific transcription factor-1 hypophysitis diagnosed post-immune checkpoint inhibitor treatment: A case with review of literature

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A highly optimized human in vitro translation system

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Bacterial muropeptides promote OXPHOS and suppress mitochondrial stress in mammals

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STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma

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Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness

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Single-molecule imaging of stochastic interactions that drive dynein activation and cargo movement in cells

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The HACE1 E3 ligase mediates RAC1-dependent control of mTOR signaling complexes

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Sep 2023
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CHCHD2 Thr61Ile mutation impairs F1F0-ATPase assembly in in vitro and in vivo models of Parkinson’s disease

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May 2023
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Deubiquitinase USP1 influences the dedifferentiation of mouse pancreatic β-cells

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ATR protects centromere identity by promoting DAXX association with PML nuclear bodies

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Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis

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ITK degradation to block T cell receptor signaling and overcome therapeutic resistance in T cell lymphomas

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Mar 2023
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Linoleic acid improves PIEZO2 dysfunction in a mouse model of Angelman Syndrome

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Feb 2023
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Illuminating cellular and extracellular vesicle-mediated communication via a split-Nanoluc reporter in vitro and in vivo

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Genetic screens reveal new targetable vulnerabilities in BAP1-deficient mesothelioma

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Structurally distinct PARP7 inhibitors provide new insights into the function of PARP7 in regulating nucleic acid-sensing and IFN-β signaling

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Allosteric regulation of DNA binding and target residence time drive the cytotoxicity of phthalazinone-based PARP-1 inhibitors

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A tick C1q protein alters infectivity of the Lyme disease agent by modulating interferon γ

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Targeting RTN4/NoGo-Receptor reduces levels of ALS protein ataxin-2

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Two distinct compartments of a ctenophore comb plate provide structural and functional integrity for the motility of giant multicilia

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Siponimod exerts neuroprotective effects on the retina and... : Neural Regeneration Research

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Sep 2022
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Cannabidiol counters the effects of a dominant-negative pathogenic Kv7.2 variant

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The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction

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Functional rewiring of G protein-coupled receptor signaling in human labor

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EAAT1-dependent slc1a3 Transcriptional Control depends on the Substrate Translocation Process

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A salivary factor binds a cuticular protein and modulates biting by inducing morphological changes in the mosquito labrum

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Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice

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Immortalized human choroid plexus endothelial cells enable an advanced endothelial-epithelial two-cell type in vitro model of the choroid plexus

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Whi3 mnemon association with endoplasmic reticulum membranes confines the memory of deceptive courtship to the yeast mother cell

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scDART-seq reveals distinct m6A signatures and mRNA methylation heterogeneity in single cells

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Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect pre-mRNA processing

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Sensory Afferent Renal Nerve Activated Gαi2 Subunit Proteins Mediate the Natriuretic, Sympathoinhibitory and Normotensive Responses to Peripheral Sodium Challenges

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Inhibition of extracellular vesicle-associated MMP2 abrogates intercellular hepatic miR-122 transfer to liver macrophages and curtails inflammation

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Crystal structure of the Tspan15 LEL domain reveals a conserved ADAM10 binding site

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ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes

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MACF1 controls skeletal muscle function through the microtubule-dependent localization of extra-synaptic myonuclei and mitochondria biogenesis

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Recombinant antibodies recognize conformation-dependent epitopes of the leucine zipper of misfolding-prone myocilin

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Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention

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Untitled document

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Epitope mapping of commercial antibodies that detect myocilin

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Structural basis for the constitutive activity and immunomodulatory properties of the Epstein-Barr virus-encoded G protein-coupled receptor BILF1

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A PGE2-MEF2A axis enables context-dependent control of inflammatory gene expression

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HDAC1 SUMOylation promotes Argonaute-directed transcriptional silencing in C. elegans

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PIE-1 SUMOylation promotes germline fates and piRNA-dependent silencing in C. elegans

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Tumor-associated autoantibodies from mouse breast cancer models are found in serum of breast cancer patients

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Pre-clinical evaluation of a whole-parasite vaccine to control human babesiosis

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The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis

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Serotypic evolution of measles virus is constrained by multiple co-dominant B cell epitopes on its surface glycoproteins

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The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolism

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Pathway-specific dysregulation of striatal excitatory synapses by LRRK2 mutations

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Stable calcium-free myocilin olfactomedin domain variants reveal challenges in differentiating between benign and glaucoma-causing mutations

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ALS-causing SOD1 mutants regulate occludin phosphorylation/ubiquitination and endocytic trafficking via the ITCH/Eps15/Rab5 axis

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Two cases of anti-PIT-1 hypophysitis exhibited as a form of paraneoplastic syndrome not associated with thymoma

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Fungal Wound Healing through Instantaneous Protoplasmic Gelation

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CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion

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Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2

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Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer

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PKC‐ and PKA‐dependent phosphorylation modulates TREK‐1 function in naïve and neuropathic rats

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TRPV4 activity regulates nuclear Ca2+ and transcriptional functions of β‐catenin in a renal epithelial cell model

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Shifts in Ribosome Engagement Impact Key Gene Sets in Neurodevelopment and Ubiquitination in Rett Syndrome

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Legionella Manipulates Non-canonical SNARE Pairing Using a Bacterial Deubiquitinase

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Emilin 2 promotes the mechanical gradient of the cochlear basilar membrane and resolution of frequencies in sound

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Cofilin is required for polarization of tension in stress fiber networks during migration

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Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity

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Development of Potent, Selective Surrogate WNT Molecules and Their Application in Defining Frizzled Requirements

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NO mediates the effect of the synthetic natriuretic peptide NPCdc on kidney and aorta in nephrectomised rats

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Extended low-resolution structure of a Leptospira antigen offers high bactericidal antibody accessibility amenable to vaccine design

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  DOI: 10.7554/eLife.30051
  
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Stable calcium-free myocilin olfactomedin domain variants reveal challenges in differentiating between benign and glaucoma-causing mutations

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Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy

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High specificity of widely used phospho‐tau antibodies validated using a quantitative whole‐cell based assay

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CTENO64 Is Required for Coordinated Paddling of Ciliary Comb Plate in Ctenophores

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Naringenin attenuates the progression of liver fibrosis via inactivation of hepatic stellate cells and profibrogenic pathways

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Do BDNF and NT‐4/5 exert synergistic or occlusive effects on corticostriatal transmission in a male mouse model of Huntington's disease?

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PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells

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Generation of a PARK2 homozygous knockout induced pluripotent stem cell line (GIBHi002-A-1) with two common isoforms abolished

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The Ubiquitin-Editing Enzyme A20 Regulates Synapse Remodeling and Efficacy

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Untitled document

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  DOI: 10.1523/JNEUROSCI.1350-18.2018
  
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Untitled document

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Untitled document

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  DOI: 10.1016/j.celrep.2018.11.092
  
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Cyclophilin D regulates neuronal activity‐induced filopodiagenesis by fine‐tuning dendritic mitochondrial calcium dynamics

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  DOI: 10.1111/jnc.14484
  
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Vasoactive intestinal peptide shapes first‐trimester placenta trophoblast, vascular, and immune cell cooperation

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Epitope mapping of commercial antibodies that detect myocilin

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Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transducer IRE1α

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Identification of piRNA Binding Sites Reveals the Argonaute Regulatory Landscape of the C. elegans Germline

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Untitled document

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ncbi.nlm.nih.gov/pmc/articles/PMC5749957/
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The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species

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