109 Matching Annotations
  1. Last 7 days
  2. 52.53.155.43 52.53.155.43
    2025.08.28.672006v1.full-html.html
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  3. Aug 2025
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    The absence of IL17A favours cytotoxic cell function and improves antigen-specific immunotherapies in pancreatic adenocarcinoma
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    onlinelibrary.wiley.com/doi/10.1002/ctm2.70442
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    41467_2025_56346_MOESM1_ESM-html.html
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    Androgen receptor–mediated assisted loading of the glucocorticoid receptor modulates transcriptional responses in prostate cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12315708/
  7. Jul 2025
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    High PER1 expression is associated with STK11 mutation and clinical biomarkers of immunotherapy resistance in lung adenocarcinoma
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    link.springer.com/article/10.1007/s00432-025-06269-9
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  10. Jun 2025
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    Conformational dynamics of a histidine molecular switch in a cation/proton antiporter
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    sciencedirect.com/science/article/pii/S0005272825000295
  12. May 2025
  13. 52.53.155.43 52.53.155.43
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    High-resolution transcriptional impact of AIRE: effects of pathogenic variants p.Arg257Ter, p.Cys311Tyr, and polygenic risk variant p.Arg471Cys
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    pmc.ncbi.nlm.nih.gov/articles/PMC12053179/
  15. Apr 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effective recognition of double-stranded RNA does not require activation of cellular inflammation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11980852/
  17. Dec 2024
  18. 52.53.155.43 52.53.155.43
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    Probiotics-sensing mechanism in neurons that initiates gut mitochondrial surveillance for pathogen defense
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    sciencedirect.com/science/article/pii/S221112472401372X
  20. Nov 2024
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Calcium-dependent regulation of neuronal excitability is rescued in Fragile X Syndrome by a tat-conjugated N-terminal fragment of FMRP
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    pmc.ncbi.nlm.nih.gov/articles/PMC11112635/
  22. Oct 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Peptidoglycan-Chi3l1 interaction shapes gut microbiota in intestinal mucus layer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11458176/
  24. Sep 2024
  25. academic.oup.com academic.oup.com
    BRAF-induced EHF Expression Affects TERT in Aggressive Papillary Thyroid Cancer
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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgae589/7740915
  26. Aug 2024
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    Functional characterization of the SDR42E1 reveals its role in vitamin D biosynthesis
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    Generation of a ZEB2 deficient human iPSC line (KICRi002A-4)
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    sciencedirect.com/science/article/pii/S1873506124002198
  29. Jul 2024
  30. www.cell.com www.cell.com
    Characterization of a lipid-based jumbo phage compartment as a hub for early phage infection
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    cell.com/cell-host-microbe/abstract/S1931-3128(24)00188-4
  31. May 2024
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    Extracellular matrix stiffness mediates insulin secretion in pancreatic islets via mechanosensitive Piezo1 channel regulated Ca2+ dynamics
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    sciencedirect.com/science/article/pii/S2590028524000085
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    Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation
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  35. Apr 2024
  36. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The early-stage clinical course of anti-pituitary-specific transcription factor-1 hypophysitis diagnosed post-immune checkpoint inhibitor treatment: A case with review of literature
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    onlinelibrary.wiley.com/doi/10.1111/jne.13395
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    A highly optimized human in vitro translation system
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    Bacterial muropeptides promote OXPHOS and suppress mitochondrial stress in mammals
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    sciencedirect.com/science/article/pii/S2211124724003954
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983107/
  40. Mar 2024
  41. www.sciencedirect.com www.sciencedirect.com
    Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness
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  42. Jan 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-molecule imaging of stochastic interactions that drive dynein activation and cargo movement in cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10798859/
  44. Oct 2023
  45. www.embopress.org www.embopress.org
    The HACE1 E3 ligase mediates RAC1-dependent control of mTOR signaling complexes
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    embopress.org/doi/10.15252/embr.202356815
  46. Sep 2023
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CHCHD2 Thr61Ile mutation impairs F1F0-ATPase assembly in in vitro and in vivo models of Parkinson’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC10479855/
  48. May 2023
  49. www.sciencedirect.com www.sciencedirect.com
    Deubiquitinase USP1 influences the dedifferentiation of mouse pancreatic β-cells
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    sciencedirect.com/science/article/pii/S2589004223008489
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    ATR protects centromere identity by promoting DAXX association with PML nuclear bodies
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    sciencedirect.com/science/article/pii/S2211124723005065
  51. Apr 2023
  52. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis
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    ITK degradation to block T cell receptor signaling and overcome therapeutic resistance in T cell lymphomas
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    sciencedirect.com/science/article/pii/S2451945623000867
  54. Mar 2023
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Linoleic acid improves PIEZO2 dysfunction in a mouse model of Angelman Syndrome
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    ncbi.nlm.nih.gov/pmc/articles/PMC9977963/
  56. Feb 2023
  57. www.sciencedirect.com www.sciencedirect.com
    Illuminating cellular and extracellular vesicle-mediated communication via a split-Nanoluc reporter in vitro and in vivo
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    sciencedirect.com/science/article/pii/S2667237523000231
  58. Jan 2023
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    Genetic screens reveal new targetable vulnerabilities in BAP1-deficient mesothelioma
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  60. Dec 2022
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    Structurally distinct PARP7 inhibitors provide new insights into the function of PARP7 in regulating nucleic acid-sensing and IFN-β signaling
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    sciencedirect.com/science/article/pii/S2451945622004184
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    Allosteric regulation of DNA binding and target residence time drive the cytotoxicity of phthalazinone-based PARP-1 inhibitors
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    sciencedirect.com/science/article/pii/S2451945622004123
  63. Nov 2022
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    A tick C1q protein alters infectivity of the Lyme disease agent by modulating interferon γ
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    sciencedirect.com/science/article/pii/S2211124722015479
  65. Oct 2022
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    Targeting RTN4/NoGo-Receptor reduces levels of ALS protein ataxin-2
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    sciencedirect.com/science/article/pii/S2211124722013559
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    Two distinct compartments of a ctenophore comb plate provide structural and functional integrity for the motility of giant multicilia
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    sciencedirect.com/science/article/pii/S0960982222016037
  68. journals.lww.com journals.lww.com
    Siponimod exerts neuroprotective effects on the retina and... : Neural Regeneration Research
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  69. Sep 2022
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cannabidiol counters the effects of a dominant-negative pathogenic Kv7.2 variant
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    ncbi.nlm.nih.gov/pmc/articles/PMC9490039/
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    The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction
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    sciencedirect.com/science/article/pii/S1931312822004073
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    Functional rewiring of G protein-coupled receptor signaling in human labor
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    sciencedirect.com/science/article/pii/S2211124722011421
  73. Aug 2022
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EAAT1-dependent slc1a3 Transcriptional Control depends on the Substrate Translocation Process
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    ncbi.nlm.nih.gov/pmc/articles/PMC9340397/
  75. Jul 2022
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    A salivary factor binds a cuticular protein and modulates biting by inducing morphological changes in the mosquito labrum
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  77. Jun 2022
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    Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice
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  79. May 2022
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    Immortalized human choroid plexus endothelial cells enable an advanced endothelial-epithelial two-cell type in vitro model of the choroid plexus
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  81. Feb 2022
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    Whi3 mnemon association with endoplasmic reticulum membranes confines the memory of deceptive courtship to the yeast mother cell
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  83. Jan 2022
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    scDART-seq reveals distinct m6A signatures and mRNA methylation heterogeneity in single cells
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    sciencedirect.com/science/article/pii/S1097276521011436
  85. www.cell.com www.cell.com
    Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect pre-mRNA processing
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    cell.com/molecular-cell/fulltext/S1097-2765(21)01085-6
  86. Dec 2021
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sensory Afferent Renal Nerve Activated Gαi2 Subunit Proteins Mediate the Natriuretic, Sympathoinhibitory and Normotensive Responses to Peripheral Sodium Challenges
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    ncbi.nlm.nih.gov/pmc/articles/PMC8669768/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of extracellular vesicle-associated MMP2 abrogates intercellular hepatic miR-122 transfer to liver macrophages and curtails inflammation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8633982/
  89. Nov 2021
  90. www.sciencedirect.com www.sciencedirect.com
    Crystal structure of the Tspan15 LEL domain reveals a conserved ADAM10 binding site
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    sciencedirect.com/science/article/pii/S0969212621003750
  91. Oct 2021
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    ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes
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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MACF1 controls skeletal muscle function through the microtubule-dependent localization of extra-synaptic myonuclei and mitochondria biogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8500715/
  94. Aug 2021
  95. www.sciencedirect.com www.sciencedirect.com
    Recombinant antibodies recognize conformation-dependent epitopes of the leucine zipper of misfolding-prone myocilin
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    sciencedirect.com/science/article/pii/S002192582100870X
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    Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention
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    Untitled document
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    biorxiv.org/content/10.1101/612911v1
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    Epitope mapping of commercial antibodies that detect myocilin
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    ncbi.nlm.nih.gov/pmc/articles/PMC6186009/
  99. Jul 2021
  100. www.sciencedirect.com www.sciencedirect.com
    Structural basis for the constitutive activity and immunomodulatory properties of the Epstein-Barr virus-encoded G protein-coupled receptor BILF1
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    sciencedirect.com/science/article/pii/S1074761321002454
  101. Jun 2021
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    A PGE2-MEF2A axis enables context-dependent control of inflammatory gene expression
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  103. May 2021
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC1 SUMOylation promotes Argonaute-directed transcriptional silencing in C. elegans
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    ncbi.nlm.nih.gov/pmc/articles/PMC8131101/
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PIE-1 SUMOylation promotes germline fates and piRNA-dependent silencing in C. elegans
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    ncbi.nlm.nih.gov/pmc/articles/PMC8131105/
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor-associated autoantibodies from mouse breast cancer models are found in serum of breast cancer patients
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    ncbi.nlm.nih.gov/pmc/articles/PMC8113561/
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    Pre-clinical evaluation of a whole-parasite vaccine to control human babesiosis
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    sciencedirect.com/science/article/pii/S1931312821001840
  108. Apr 2021
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    The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis
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    Serotypic evolution of measles virus is constrained by multiple co-dominant B cell epitopes on its surface glycoproteins
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    sciencedirect.com/science/article/pii/S2666379121000410
  111. Mar 2021
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    The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolism
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  113. Feb 2021
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pathway-specific dysregulation of striatal excitatory synapses by LRRK2 mutations
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    ncbi.nlm.nih.gov/pmc/articles/PMC7609054/
  115. www.jbc.org www.jbc.org
    Stable calcium-free myocilin olfactomedin domain variants reveal challenges in differentiating between benign and glaucoma-causing mutations
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    jbc.org/content/294/34/12717.long
  116. www.sciencedirect.com www.sciencedirect.com
    ALS-causing SOD1 mutants regulate occludin phosphorylation/ubiquitination and endocytic trafficking via the ITCH/Eps15/Rab5 axis
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    sciencedirect.com/science/article/pii/S0969996121000644
  117. Jan 2021
  118. academic.oup.com academic.oup.com
    Two cases of anti-PIT-1 hypophysitis exhibited as a form of paraneoplastic syndrome not associated with thymoma
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    academic.oup.com/jes/article/5/3/bvaa194/6056675
  119. Dec 2020
  120. www.cell.com www.cell.com
    Fungal Wound Healing through Instantaneous Protoplasmic Gelation
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    cell.com/current-biology/abstract/S0960-9822(20)31520-7
  121. Nov 2020
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    CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion
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  123. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2
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    pubmed.ncbi.nlm.nih.gov/33160446/
  124. Oct 2020
  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer
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    ncbi.nlm.nih.gov/pmc/articles/PMC7560607/
  126. onlinelibrary.wiley.com onlinelibrary.wiley.com
    PKC‐ and PKA‐dependent phosphorylation modulates TREK‐1 function in naïve and neuropathic rats
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15204
  127. onlinelibrary.wiley.com onlinelibrary.wiley.com
    TRPV4 activity regulates nuclear Ca2+ and transcriptional functions of β‐catenin in a renal epithelial cell model
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    onlinelibrary.wiley.com/doi/10.1002/jcp.30096
  128. Sep 2020
  129. www.sciencedirect.com www.sciencedirect.com
    Shifts in Ribosome Engagement Impact Key Gene Sets in Neurodevelopment and Ubiquitination in Rett Syndrome
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    sciencedirect.com/science/article/pii/S2211124720302886
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    Legionella Manipulates Non-canonical SNARE Pairing Using a Bacterial Deubiquitinase
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  131. advances.sciencemag.org advances.sciencemag.org
    Emilin 2 promotes the mechanical gradient of the cochlear basilar membrane and resolution of frequencies in sound
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