247 Matching Annotations
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    2025.08.17.670702v1.full-html.html
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  3. Aug 2025
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    Enhancer remodeling by OTX2 directs specification and patterning of mammalian definitive endoderm
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    Identification and characterization of early human photoreceptor states and cell-state-specific retinoblastoma-related features
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    elifesciences.org/articles/101918
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    Live imaging endogenous transcription factor dynamics reveals mechanisms of epiblast and primitive endoderm fate segregation
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  7. Jul 2025
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    Inside‐Out IP 3‐Mediated G Protein‐Coupled Receptor Activation Drives Intercellular Ca2+ Signaling in the Vascular Endothelium
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    Generation of germinal-vesicle oocytes from mouse embryonic stem cells under an ovarian soma-free condition
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    Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids
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  11. Jun 2025
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    Ethanol inhibits dorsomedial striatum acetylcholine release
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    Generation of Human Naïve Pluripotent Stem Cell-Derived Blastoids in Thermoformed Microwell Platforms
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    TBX3 advances the developmental chromatin landscape toward the hepatic fate
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    Characterization of a mouse model of osteoarticular infection using clinical isolates of Staphylococcus aureus
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    Rapid generation of functional vascular organoids via simultaneous transcription factor activation of endothelial and mural lineages
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    Collapse of late endosomal pH elicits a rapid Rab7 response via the V-ATPase and RILP
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  18. May 2025
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    Disrupted endosomal trafficking of the Vangl-Celsr polarity complex underlies congenital anomalies in Xenopus trachea-esophageal morphogenesis
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    Microglia overexpressing brain-derived neurotrophic factor promote vascular repair and functional recovery in mice after spinal cord injury
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    Viral-mediated Pou5f1 (Oct4) overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Müller glia
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    Collapse of late endosomal pH elicits a rapid Rab7 response via the V-ATPase and RILP
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    Neuroendocrine Differentiation in Prostate Cancer Requires ASCL1
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    CSP ubiquitylation favours Plasmodium berghei survival during early liver stage infection
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  25. Apr 2025
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    A cost- and time-efficient method for high-throughput cryoprocessing and tissue analysis using multiplexed tissue molds
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    GABAAR-δ-subunit mediates increased GABAergic inhibition in cardiac DMV neurons after high-fat diet
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    KRIT1 heterozygous mutations are sufficient to induce a pathological phenotype in patient-derived iPSC models of cerebral cavernous malformation
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    Ciliary marginal zone of the developing human retina maintains retinal progenitor cells until late gestational stages
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  32. Mar 2025
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    Morphology and connectivity of retinal horizontal cells in two avian species
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    Protective ApoE variants support neuronal function by extracting peroxidated lipids
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  38. Feb 2025
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  40. Jan 2025
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  43. Dec 2024
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    CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells
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    A multiplexed, single-cell sequencing screen identifies compounds that increase neurogenic reprogramming of murine Muller glia
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    Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer
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  50. Nov 2024
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    AMPK regulates Bcl2-L-13-mediated mitophagy induction for cardioprotection
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    Granulins rescue inflammation, lysosome dysfunction, lipofuscin, and neuropathology in a mouse model of progranulin deficiency
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    Spatial transcriptomic landscape unveils immunoglobin-associated senescence as a hallmark of aging
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  54. Oct 2024
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  56. Sep 2024
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    Control of epigenomic landscape and development of fetal male germ cells through L-serine metabolism
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    MTSS1 Regulation of Actin-Nucleating Formin DAAM1 in Dendritic Filopodia Determines Final Dendritic Configuration of Purkinje Cells
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  61. Aug 2024
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    Neuroepithelial bodies and terminal bronchioles are niches for distinctive club cells that repair the airways following acute notch inhibition
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    BDNF-dependent nano-organization of Neogenin and the WAVE Regulatory Complex promotes actin remodelling in dendritic spines
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    Generation of two isogenic patient-derived human-induced pluripotent stem cell clones with 6q27 deletion
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    Neuron type-specific proteomics reveals distinct Shank3 proteoforms in iPSNs and dSPNs lead to striatal synaptopathy in Shank3B–/– mice
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    Serum Amyloid A1/Toll-Like Receptor-4 Axis, an Important Link between Inflammation and Outcome of TBI Patients
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  67. Jul 2024
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    Protocol for mapping cell lineage and cell-type identity of clonally-related cells in situ using MADM-CloneSeq
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    Macrophages preserve endothelial cell specialization in the adrenal gland to modulate aldosterone secretion and blood pressure
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    Protocol for iterative indirect immunofluorescence imaging in cultured cells, tissue sections, and metaphase chromosome spreads
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    A three-dimensional tissue-engineered rostral migratory stream as an in vitro platform for subventricular zone-derived cell migration
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  73. Jun 2024
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    The Aging Lacrimal Gland of Female C57BL/6J Mice Exhibits Multinucleate Macrophage Infiltration Associated With Lipid Dysregulation
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    Inhibition of HDAC activity directly reprograms murine embryonic stem cells to trophoblast stem cells
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  77. May 2024
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    The first two blastomeres contribute unequally to the human embryo
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    Systemic Phospho-Defective and Phospho-Mimetic Drp1 Mice Exhibit Normal Growth and Development with Altered Anxiety-like Behavior
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    ARID1B controls transcriptional programs of axon projection in an organoid model of the human corpus callosum
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    Vascular architecture regulates mesenchymal stromal cell heterogeneity via P53-PDGF signaling in the mouse incisor
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    Astrocytic Slc4a4 regulates blood-brain barrier integrity in healthy and stroke brains via a CCL2-CCR2 pathway and NO dysregulation
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    Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Parkinson’s disease
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  85. Apr 2024
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    Mannose controls mesoderm specification and symmetry breaking in mouse gastruloids
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    Ptch1 is essential for cochlear marginal cell differentiation and stria vascularis formation
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  88. Mar 2024
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    Pten regulates endocytic trafficking of cell adhesion and Wnt signaling molecules to pattern the retina
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    Mechanisms of HIV-Mediated Blood-Brain Barrier Compromise and Leukocyte Transmigration under the Current Antiretroviral Era.
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    Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury
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  92. Feb 2024
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    Dorsal motor vagal neurons can elicit bradycardia and reduce anxiety-like behavior
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    The HRI branch of the integrated stress response selectively triggers mitophagy
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    Generation of human induced pluripotent stem cell line derived from Becker muscular dystrophy patient with CRISPR/Cas9-mediated correction of DMD gene mutation
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  96. Jan 2024
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Notch receptor-ligand binding facilitates extracellular vesicle-mediated neuron-to-neuron communication
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    Human conjunctiva organoids to study ocular surface homeostasis and disease
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    Renal macrophages monitor and remove particles from urine to prevent tubule obstruction
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    CHTOP Alleviates Cerebral Ischemia/Reperfusion-Induced Injury by Regulating RNA Alternative Splicing
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    Human fetal brain self-organizes into long-term expanding organoids
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  102. Dec 2023
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    Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection
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    Multipotent progenitors instruct ontogeny of the superior colliculus
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  105. Nov 2023
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    Spatial memory requires hypocretins to elevate medial entorhinal gamma oscillations
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