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Cooperativity between Ras pathway mutations in colonic tumorigenesis

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1. scibot 10 Sep 2025
  
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  DOI: 10.1101/2025.09.05.673994
  
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biorxiv.org/content/10.1101/2025.09.05.673994v1
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Combining light-induced aggregation and biotin proximity labeling implicates endolysosomal proteins in early α-synuclein oligomerization

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.isci.2025.112823
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12221657/
Apr 2025
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Early A-synuclein aggregation decreases corticostriatal glutamate drive and synapse density

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1. scibot 17 Apr 2025
  
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  DOI: 10.1016/j.nbd.2025.106918
  
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sciencedirect.com/science/article/pii/S0969996125001342
Sep 2024
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Signal flow in the NMDA receptor–dependent phosphoproteome regulates postsynaptic plasticity for aversive learning

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1. scibot 26 Sep 2024
  
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  DOI: 10.1126/scisignal.ado9852
  
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science.org/doi/10.1126/scisignal.ado9852
Jul 2024
www.cell.com www.cell.com

Combination of compound screening with an animal model identifies pentamidine to prevent Chlamydia trachomatis infection

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  DOI: 10.1016/j.xcrm.2024.101643
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00357-4
Jun 2024
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  D. Secondary antibodies used for immunoblotting or confocal imaging
  
  DOI: 10.1101/2022.03.30.486322
  
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May 2024
www.sciencedirect.com www.sciencedirect.com

Direct interrogation of context-dependent GPCR activity with a universal biosensor platform

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1. scibot 22 May 2024
  
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  DOI: 10.1016/j.cell.2024.01.028
  
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sciencedirect.com/science/article/pii/S0092867424000655
Mar 2024
www.nature.com www.nature.com

Clinically-observed FOXA1 mutations upregulate SEMA3C through transcriptional derepression in prostate cancer

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1. scibot 28 Mar 2024
  
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  DOI: 10.1038/s41598-024-57854-w
  
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nature.com/articles/s41598-024-57854-w
Feb 2024
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NMDAR Phosphoproteome Controls Synaptic Growth and Learning

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1. scibot 15 Feb 2024
  
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  DOI: 10.1101/2023.12.15.571360
  
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  DOI: 10.1101/2023.12.15.571360
  
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biorxiv.org/content/10.1101/2023.12.15.571360v1
Nov 2023
journals.physiology.org journals.physiology.org

2022 Cannon lecture: an ode to signal transduction: how the growth hormone pathway revealed insight into height, malignancy, and obesity

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1. scibot 04 Nov 2023
  
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  DOI: 10.1152/ajpendo.00265.2023
  
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journals.physiology.org/doi/10.1152/ajpendo.00265.2023
52.53.155.43 52.53.155.43

2022 Cannon Lecture: An ode to signal transduction - how the growth hormone pathway revealed insight into height, malignancy and obesity

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  DOI: 10.1152/ajpendo.00265.2023
  
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52.53.155.43/ef68857be5878166044b27eea5f2fa3e21ebcf86/carter-su-et-al-2023-2022-cannon-lecture-an-ode-to-signal-transduction-how-the-growth-hormone-pathway-revealed-insight-html.html
Sep 2023
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The C2 domain of calpain 5 contributes to enzyme activation and membrane localization

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1. scibot 23 Sep 2023
  
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  DOI: 10.1016/j.bbamcr.2021.119019
  
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sciencedirect.com/science/article/pii/S0167488921000732
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The Evaluation of Rac1 Signaling as a Potential Therapeutic Target of Alzheimer’s Disease

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1. scibot 16 Aug 2023
  
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  DOI: 10.3390/ijms241511880
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10418761/
Jul 2023
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Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation

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1. scibot 27 Jul 2023
  
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  DOI: 10.1016/j.devcel.2023.07.001
  
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sciencedirect.com/science/article/pii/S1534580723003313
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Oncogenic K-Ras suppresses global miRNA function

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  DOI: 10.1016/j.molcel.2023.06.008
  
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sciencedirect.com/science/article/pii/S109727652300429X
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Plasmodium sporozoites require the protein B9 to invade hepatocytes

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1. scibot 11 Feb 2023
  
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  DOI: 10.1016/j.isci.2023.106056
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9906020/
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SAYSD1 senses UFMylated ribosome to safeguard co-translational protein translocation at the endoplasmic reticulum

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1. scibot 24 Jan 2023
  
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  DOI: 10.1016/j.celrep.2023.112028
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10010011/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Rho-Kinase/ROCK Phosphorylates PSD-93 Downstream of NMDARs to Orchestrate Synaptic Plasticity

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1. scibot 11 Jan 2023
  
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  DOI: 10.3390/ijms24010404
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9820267/
Dec 2022
52.53.155.43 52.53.155.43

R17C Mutation in Photoreceptor Disc-Specific Protein, PRCD, Results in Additional Lipidation Altering Protein Stability and Subcellular Localization

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1. scibot 06 Dec 2022
  
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  DOI: 10.3390/ijms231810802
  
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52.53.155.43/80acc487fd025450db10f23a12357f3c613cec01/ijms-23-10802-v2-html.html
Aug 2022
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Increasing cell size remodels the proteome and promotes senescence

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1. scibot 22 Aug 2022
  
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  DOI: 10.1016/j.molcel.2022.07.017
  
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sciencedirect.com/science/article/pii/S1097276522007134
May 2022
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Rho–Rho-Kinase Regulates Ras-ERK Signaling Through SynGAP1 for Dendritic Spine Morphology

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1. scibot 28 May 2022
  
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  DOI: 10.1007/s11064-022-03623-y
  
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link.springer.com/article/10.1007/s11064-022-03623-y
Mar 2022
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Regulation of GTPase function by autophosphorylation

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  DOI: 10.1016/j.molcel.2022.02.011
  
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sciencedirect.com/science/article/pii/S1097276522001162
Feb 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease

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1. scibot 11 Feb 2022
  
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  DOI: 10.1016/j.cels.2022.01.005
  
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2. scibot 11 Feb 2022
  
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  DOI: 10.1016/j.cels.2022.01.005
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9317655/
Jan 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

KANPHOS: A Database of Kinase-Associated Neural Protein Phosphorylation in the Brain

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1. scibot 13 Jan 2022
  
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  DOI: 10.3390/cells11010047
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8750479/
Dec 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Muscarinic signaling regulates voltage-gated potassium channel KCNQ2 phosphorylation in the nucleus accumbens via protein kinase C for aversive learning

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1. scibot 22 Dec 2021
  
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  DOI: 10.1111/jnc.15555
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15555
Nov 2021
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Rescue of α-synuclein aggregation in Parkinson’s patient neurons by synergistic enhancement of ER proteostasis and protein trafficking

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1. scibot 18 Nov 2021
  
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  DOI: 10.1016/j.neuron.2021.10.032
  
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sciencedirect.com/science/article/pii/S089662732100862X
Aug 2021
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ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency

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  DOI: 10.1016/j.molcel.2021.07.018
  
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sciencedirect.com/science/article/pii/S1097276521005876
Jul 2021
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F-Actin Interactome Reveals Vimentin as a Key Regulator of Actin Organization and Cell Mechanics in Mitosis

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1. scibot 31 Jul 2021
  
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  Alexa Fluor 680
  
  DOI: 10.1016/j.devcel.2019.12.011
  
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sciencedirect.com/science/article/pii/S1534580719310329
www.cell.com www.cell.com

Neuron-Specific Genome Modification in the Adult Rat Brain Using CRISPR-Cas9 Transgenic Rats

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1. scibot 31 Jul 2021
  
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  DOI: 10.1016/j.neuron.2019.01.035
  
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cell.com/neuron/fulltext/S0896-6273(19)30062-5
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Effects of Withdrawal from Cocaine Self-Administration on Rat Orbitofrontal Cortex Parvalbumin Neurons Expressing Cre recombinase: Sex-Dependent Changes in Neuronal Function and Unaltered Serotonin Signaling

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1. scibot 13 Jul 2021
  
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  A21058
  
  DOI: 10.1523/ENEURO.0017-21.2021
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8266218/
Apr 2021
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Discovery of an Inhibitor for Bacterial 3-Mercaptopyruvate Sulfurtransferase that Synergistically Controls Bacterial Survival

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1. scibot 28 Apr 2021
  
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  DOI: 10.1016/j.chembiol.2020.10.012
  
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sciencedirect.com/science/article/pii/S2451945620304281
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The C2 domain of calpain 5 contributes to enzyme activation and membrane localization

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1. scibot 03 Apr 2021
  
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  DOI: 10.1016/j.bbamcr.2021.119019
  
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sciencedirect.com/science/article/pii/S0167488921000732
Mar 2021
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Detection of pathological alpha-synuclein aggregates in human iPSC-derived neurons and tissue

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1. scibot 09 Mar 2021
  
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  DOI: 10.1016/j.xpro.2021.100372
  
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sciencedirect.com/science/article/pii/S2666166721000794
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Genome-wide CRISPR Screen Reveals a Role for the Non-Canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function

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  DOI: 10.1016/j.immuni.2020.06.011
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7341821/
Oct 2020
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Persistent DNA Damage and Senescence in the Placenta Impacts Developmental Outcomes of Embryos

1
1. scibot 16 Oct 2020
  
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  RRID:AB_2535724
  
  DOI: 10.1016/j.devcel.2020.05.025
  
  Resource: (Thermo Fisher Scientific Cat# A-21058, RRID:AB_2535724)
  
  Curator: @evieth
  
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  RRIDCUR:Validated RRID:AB_2535724
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sciencedirect.com/science/article/pii/S1534580720304147
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Transferrin Receptor Is a Specific Ferroptosis Marker

1
1. scibot 23 Sep 2020
  
  in Public
  
  RRID:AB_2535724
  
  DOI: 10.1016/j.celrep.2020.02.049
  
  Resource: (Thermo Fisher Scientific Cat# A-21058, RRID:AB_2535724)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7172030/
www.nature.com www.nature.com

High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening

1
1. scibot 06 Sep 2020
  
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  RRID:AB_2535724
  
  DOI: 10.1038/s41467-020-17209-1
  
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nature.com/articles/s41467-020-17209-1
Jan 2020
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The E3 Ubiquitin Ligase Mind Bomb 1 Controls Adenovirus Genome Release at the Nuclear Pore Complex

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2535724
  
  DOI: 10.1016/j.celrep.2019.11.064
  
  Resource: (Thermo Fisher Scientific Cat# A-21058, RRID:AB_2535724)
  
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sciencedirect.com/science/article/pii/S2211124719315554
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Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer’s Disease

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2535724
  
  DOI: 10.1016/j.celrep.2019.08.104
  
  Resource: (Thermo Fisher Scientific Cat# A-21058, RRID:AB_2535724)
  
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sciencedirect.com/science/article/pii/S2211124719311660
journals.plos.org journals.plos.org

Inflammatory monocytes provide a niche for Salmonella expansion in the lumen of the inflamed intestine

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2535724
  
  DOI: 10.1371/journal.ppat.1007847
  
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journals.plos.org/plospathogens/article
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Phosphorylation of Npas4 by MAPK Regulates Reward-Related Gene Expression and Behaviors

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2535724
  
  DOI: 10.1016/j.celrep.2019.10.116
  
  Resource: (Thermo Fisher Scientific Cat# A-21058, RRID:AB_2535724)
  
  Curator: @ethanbadger
  
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  RRID:AB_2535724 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719314494
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Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D

1
1. scibot 13 Jan 2020
  
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  AB_2535724
  
  DOI: 10.1016/j.celrep.2019.07.026
  
  Resource: (Thermo Fisher Scientific Cat# A-21058, RRID:AB_2535724)
  
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  RRID:AB_2535724 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719309234
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Stress-Induced Cellular Clearance Is Mediated by the SNARE Protein ykt6 and Disrupted by α-Synuclein

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2535724
  
  DOI: 10.1016/j.neuron.2019.09.001
  
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  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S0896627319307743
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_2535724
  
  DOI: 10.1016/j.celrep.2018.12.041
  
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  Curator: @evieth
  
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sciencedirect.com/science/article/pii/S2211124718319715
www.cell.com www.cell.com

Neuron-Specific Genome Modification in the Adult Rat Brain Using CRISPR-Cas9 Transgenic Rats

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2535724
  
  DOI: 10.1016/j.neuron.2019.01.035
  
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cell.com/neuron/fulltext/S0896-6273(19)30062-5
Nov 2018
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Astrocyte-Secreted Chordin-like 1 Drives Synapse Maturation and Limits Plasticity by Increasing Synaptic GluA2 AMPA Receptors

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2535724
  
  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S0896627318308456
Nov 2017
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Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways

1
1. scibot 08 Nov 2017
  
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  AB_2535724
  
  Curator: @Zeljana_Babic
  
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sciencedirect.com/science/article/pii/S1097276517300564
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Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules

1
1. scibot 08 Nov 2017
  
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  AB_2535724
  
  Curator: @Jmenke
  
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  RRID:AB_2535724 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867416316075