419 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells
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    1. scibot 19 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724004443
  3. Apr 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lineage-tracing reveals an expanded population of NPY neurons in the inferior colliculus
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  5. 52.53.155.43 52.53.155.43
    elife-92755-v2-html.html
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    Tumor cell-intrinsic epigenetic dysregulation shapes cancer-associated fibroblasts heterogeneity to metabolically support pancreatic cancer
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    sciencedirect.com/science/article/pii/S1535610824000904
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    Microtubule-associated protein MAP7 promotes tubulin posttranslational modifications and cargo transport to enable osmotic adaptation
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    sciencedirect.com/science/article/pii/S1534580724001904
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    NSAID targets SIRT3 to trigger mitochondrial dysfunction and gastric cancer cell death
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    ncbi.nlm.nih.gov/pmc/articles/PMC10972828/
  9. Mar 2024
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    Maladaptation of dentate gyrus mossy cells mediates contextual discrimination deficit after traumatic stress
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    Rho GTPase signaling and mDia facilitate endocytosis via presynaptic actin
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      DOI: 10.7554/eLife.92755

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  12. rupress.org rupress.org
    Rab32 family proteins regulate autophagosomal components recycling
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    rupress.org/jcb/article/223/3/e202306040/276549/Rab32-family-proteins-regulate-autophagosomal
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    The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation
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      DOI: 10.7554/eLife.87386

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    Ankrd26 is a retinoic acid-responsive plasma membrane-binding and -shaping protein critical for proper cell differentiation
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    1. scibot 19 Mar 2024
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    sciencedirect.com/science/article/pii/S2211124724002675
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    Improved detection of colibactin-induced mutations by genotoxic E. coli in organoids and colorectal cancer
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    Protocol to analyze Drosophila intestinal tumor cellular heterogeneity using immunofluorescence imaging and nuclear size quantification
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    C17orf80 binds the mitochondrial genome to promote its replication
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  18. 52.53.155.43 52.53.155.43
    JNEUROSCI.0918-23.2024.full-html.html
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    Pip5k1γ regulates axon formation by limiting Rap1 activity
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      DOI: 10.26508/lsa.202302383

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    ncbi.nlm.nih.gov/pmc/articles/PMC10912816/
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    Mechanisms of HIV-Mediated Blood-Brain Barrier Compromise and Leukocyte Transmigration under the Current Antiretroviral Era.
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    sciencedirect.com/science/article/pii/S2589004224004577
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    In vivo PSC differentiation as a platform to identify factors for improving the engraftability of cultured muscle stem cells
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      DOI: 10.3389/fcell.2024.1362671

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  22. Feb 2024
  23. elifesciences.org elifesciences.org
    Mechanical activation of TWIK-related potassium channel by nanoscopic movement and rapid second messenger signaling
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      DOI: 10.7554/eLife.89465

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    elifesciences.org/articles/89465
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    Spatial transcriptomics suggests that alterations occur in the preneoplastic breast microenvironment of BRCA1/2 mutation carriers
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      DOI: 10.1158/1541-7786.MCR-23-0489

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    aacrjournals.org/mcr/article/22/2/169/733690/Spatial-Transcriptomics-Suggests-That-Alterations
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    Kin17 regulates proper cortical localization of Miranda in Drosophila neuroblasts by regulating Flfl expression
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    DLK signaling in axotomized neurons triggers complement activation and loss of upstream synapses
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    Vibrio cholerae arrests intestinal epithelial proliferation through T6SS-dependent activation of the bone morphogenetic protein pathway
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  28. www.biorxiv.org www.biorxiv.org
    Targeting NGF but not VEGF or BDNF signaling reduces endometriosis-associated pain in mice
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      DOI: 10.1101/2023.12.05.570181

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    3D matrix adhesion feedback controls nuclear force coupling to drive invasive cell migration
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  30. 52.53.155.43 52.53.155.43
    Adrenal Abcg1 controls cholesterol flux and steroidogenesis
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      DOI: 10.1210/endocr/bqae014

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  31. Jan 2024
  32. www.sciencedirect.com www.sciencedirect.com
    EXO1 protects BRCA1-deficient cells against toxic DNA lesions
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      DOI: 10.1016/j.molcel.2023.12.039

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    sciencedirect.com/science/article/pii/S1097276523010857
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid β aggregates in vivo in a mouse model of Alzheimer’s disease
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      DOI: 10.1186/s13024-024-00702-2

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  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interaction of PINK1 with nucleotides and kinetin
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      DOI: 10.1126/sciadv.adj7408

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    Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk
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    Predicting gene-level sensitivity to JAK-STAT signaling perturbation using a mechanistic-to-machine learning framework
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  37. www.jneurosci.org www.jneurosci.org
    Two-Step Actions of Testicular Androgens in the Organization of a Male-Specific Neural Pathway from the Medial Preoptic Area to the Ventral Tegmental Area for Modulating Sexually Motivated Behavior
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      DOI: 10.1523/JNEUROSCI.0361-23.2023

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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ULK phosphorylation of STX17 controls autophagosome maturation via FLNA
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      DOI: 10.1083/jcb.202211025

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    ncbi.nlm.nih.gov/pmc/articles/PMC10316704/
  39. Dec 2023
  40. www.sciencedirect.com www.sciencedirect.com
    Cortical circuitry mediating interareal touch signal amplification
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    sciencedirect.com/science/article/pii/S2211124723015449
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    Genome-wide study reveals novel roles for formin-2 in axon regeneration as a microtubule dynamics regulator and therapeutic target for nerve repair
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      DOI: 10.1016/j.neuron.2023.11.011

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      DOI: 10.1016/j.neuron.2023.11.011

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    sciencedirect.com/science/article/pii/S0896627323008851
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    HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function
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    Mucosal and systemic antigen-specific antibody responses correlate with protection against active tuberculosis in nonhuman primates
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      DOI: 10.1016/j.ebiom.2023.104897

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    Eclosion muscles secrete ecdysteroids to initiate asymmetric intestinal stem cell division in Drosophila
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    Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy
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    Towards modular engineering of cell signalling: Topographically-textured microparticles induce osteogenesis via activation of canonical hedgehog signalling
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    DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C
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    Linear ubiquitination at damaged lysosomes induces local NF-κB activation and controls cell survival
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    Review Commons Transfer: Schwann cells are axo-protective after injury irrespective of myelination status in mouse Schwann cell–neuron cocultures
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    Establishment of heterozygous and homozygous SHANK3 knockout clonal pluripotent stem cells from the parental hESC line SA001 using CRISPR/Cas9
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    Social recognition memory differences between mouse strains: On the effects of social isolation, adult neurogenesis, and environmental enrichment
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    Pleiotrophin ameliorates age-induced adult hippocampal neurogenesis decline and cognitive dysfunction
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    Heroin Self-Administration and Extinction Increase Prelimbic Cortical Astrocyte–Synapse Proximity and Alter Dendritic Spine Morphometrics That Are Reversed by N-Acetylcysteine
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    Synaptotagmin-1-dependent phasic axonal dopamine release is dispensable for basic motor behaviors in mice
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    Super-resolution imaging unveils the self-replication of tau aggregates upon seeding
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    The Rho1 GTPase controls anillo-septin assembly to facilitate contractile ring closure during cytokinesis
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    Convergence of multiple RNA-silencing pathways on GW182/TNRC6
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    Spd-2 gene duplication reveals cell-type-specific pericentriolar material regulation
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    Golgi satellites are essential for polysialylation of NCAM and expression of LTP at distal synapses
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    FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics
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    CRISPR/Cas9-mediated generation of human embryonic stem cell sub-lines with HPRT1 gene knockout to model Lesch Nyhan disease
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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The septate junction component bark beetle is required for Drosophila intestinal barrier function and homeostasis
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    LRP12 is an endogenous transmembrane inactivator of α4 integrins
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    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
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    Vaccine elicitation and structural basis for antibody protection against alphaviruses
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    Biofilm formation on human immune cells is a multicellular predation strategy of Vibrio cholerae
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    LZTR1 mutation mediates oncogenesis through stabilization of EGFR and AXL
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    Asynchronous transcription and translation of neurotransmitter-related genes characterize the initial stages of neuronal maturation in Drosophila
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    The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins
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    Irisin acts through its integrin receptor in a two-step process involving extracellular Hsp90α
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    Pharyngeal Mechanosensory Neurons Control Food Swallow in Drosophila melanogaster
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  104. May 2023
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    Distinct axo-protective and axo-destructive roles for Schwann cells after injury in a novel compartmentalised mouse myelinating coculture system
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    Phospholipid scramblase Xkr8 is required for developmental axon pruning via phosphatidylserine exposure
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    Unconventional initiation of PINK1/Parkin mitophagy by Optineurin
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    Upregulated GIRK2 counteracts ethanol-induced changes in excitability and respiration in human neurons
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  109. Apr 2023
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    Vascular cells improve functionality of human cardiac organoids
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    Columnar neurons support saccadic bar tracking in Drosophila
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    Nucleation and Dissolution Mechanism Underlying ALS/FTLD-linked FUS Condensates
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    Gαs slow conformational transition upon GTP binding and a novel Gαs regulator
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    Exercise training remodels inguinal white adipose tissue through adaptations in innervation, vascularization, and the extracellular matrix
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    Circadian protein TIMELESS regulates synaptic function and memory by modulating cAMP signaling
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  116. Mar 2023
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    Nuclease activity of Plasmodium falciparum Alba family protein PfAlba3
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    Genetic dissection of mutual interference between two consecutive learning tasks in Drosophila
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    Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid β aggregates in vivo in a mouse model of Alzheimer’s disease
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    A hydraulic feedback loop between mesendoderm cell migration and interstitial fluid relocalization promotes embryonic axis formation in zebrafish
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    Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene induction
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    Bone marrow Adipoq-lineage progenitors are a major cellular source of M-CSF that dominates bone marrow macrophage development, osteoclastogenesis, and bone mass
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    Real-time mechanisms of exacerbated synaptic remodeling by microglia in acute models of systemic inflammation and tauopathy
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    Tumor suppressor p53 regulates heat shock factor 1 protein degradation in Huntington’s disease
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    Bacillus thuringiensis toxins divert progenitor cells toward enteroendocrine fate by decreasing cell adhesion with intestinal stem cells in Drosophila
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  126. Feb 2023
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    GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
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    3D human induced pluripotent stem cell–derived bioengineered skeletal muscles for tissue, disease and therapy modeling
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    Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules
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    Behavioral state-dependent modulation of insulin-producing cells in Drosophila
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    A novel period mutation implicating nuclear export in temperature compensation of the Drosophila circadian clock
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    Characterization of the structure and control of the blood-nerve barrier identifies avenues for therapeutic delivery
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    CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performance
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    Distinct niche structures and intrinsic programs of fallopian tube and ovarian surface epithelial cells
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    The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice
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  140. Dec 2022
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    The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities
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    Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis
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    In vitro-derived medium spiny neurons recapitulate human striatal development and complexity at single-cell resolution
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    Structurally distinct PARP7 inhibitors provide new insights into the function of PARP7 in regulating nucleic acid-sensing and IFN-β signaling
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    Generation of a homozygous FIS1 knockout human embryonic stem cell line GIBHe015-B by CRISPR/Cas9 system
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    A novel function for the sperm adhesion protein IZUMO1 in cell–cell fusion
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    Antiviral function and viral antagonism of the rapidly evolving dynein activating adaptor NINL
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    Membrane phosphoinositides regulate GPCR-β-arrestin complex assembly and dynamics
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    Physical confinement promotes mesenchymal trans-differentiation of invading transformed cells in vivo
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    HIV-1 Vpu restricts Fc-mediated effector functions in vivo
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    Dual anti-angiogenic and anti-metastatic activity of myriocin synergistically enhances the anti-tumor activity of cisplatin
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    Identification of proteomic landscape of drug-binding proteins in live cells by proximity-dependent target ID
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    Sleep need-dependent changes in functional connectivity facilitate transmission of homeostatic sleep drive
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    A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration
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    Photoreceptors generate neuronal diversity in their target field through a Hedgehog morphogen gradient in Drosophila
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    Neural crest cell-placodal neuron interactions are mediated by Cadherin-7 and N-cadherin during early chick trigeminal ganglion assembly
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    Generation of iPSC lines from hereditary spastic paraplegia 56 (SPG56) patients and family members carrying CYP2U1 mutations
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    Robust genome editing via modRNA-based Cas9 or base editor in human pluripotent stem cells
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    Negative autoregulation mitigates collateral RNase activity of repeat-targeting CRISPR-Cas13d in mammalian cells
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    ARHGEF9 regulates melanoma morphogenesis in environments with diverse geometry and elasticity by promoting filopodial-driven adhesion
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    An inhibitory brainstem input to dopamine neurons encodes nicotine aversion
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    Role of Constitutive STAR in Mitochondrial Structure and Function in MA-10 Leydig Cells
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    EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks
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  181. Jun 2022
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    Robust anti-SARS-CoV2 single domain antibodies cross neutralize multiple viruses
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    MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression
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  187. May 2022
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    Regionally defined proteomic profiles of human cerebral tissue and organoids reveal conserved molecular modules of neurodevelopment
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    Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis
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    Acute (R,S)-Ketamine Administration Induces Sex-Specific Behavioral Effects in Adolescent but Not Aged Mice
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    Retinoic acid-induced protein 14 controls dendritic spine dynamics associated with depressive-like behaviors
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  193. elifesciences.org elifesciences.org
    MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior
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  194. Apr 2022
  195. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    RBPMS is an RNA-binding protein that mediates cardiomyocyte binucleation and cardiovascular development
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    Age-Dependent Increase in Schmidt-Lanterman Incisures and a Cadm4-Associated Membrane Skeletal Complex in Fatty Acid 2-hydroxylase Deficient Mice: a Mouse Model of Spastic Paraplegia SPG35
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    Secreted NF-κB suppressive microbial metabolites modulate gut inflammation
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    Force-dependent intercellular adhesion strengthening underlies asymmetric adherens junction contraction
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    Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease
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  201. Mar 2022
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    Lipid-mediated phase separation of AGO proteins on the ER controls nascent-peptide ubiquitination
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    Endosomal phosphatidylinositol 3-phosphate controls synaptic vesicle cycling and neurotransmission
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    The transcription factor Xrp1 orchestrates both reduced translation and cell competition upon defective ribosome assembly or function
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    Pathways for memory, cognition and emotional context: hippocampal, subgenual area 25 and amygdalar axons show unique interactions in the primate thalamic Reuniens Nucleus
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    Isogenic human SNCA gene dosage induced pluripotent stem cells to model Parkinson’s disease
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    Cholesterol biosynthesis defines oligodendrocyte precursor heterogeneity between brain and spinal cord
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  210. Feb 2022
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    Fat3 acts through independent cytoskeletal effectors to coordinate asymmetric cell behaviors during polarized circuit assembly
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  213. Jan 2022
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    The lateral posterior clock neurons (LPN) of Drosophila melanogaster express three neuropeptides and have multiple connections within the circadian clock network and beyond
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    Human induced pluripotent stem cells generated from epilepsy patients for use as in vitro models for drug screening
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  216. Dec 2021
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    The balance of mitochondrial fission and fusion in cortical axons depends on the kinases SadA and SadB
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    Myelination Deficits in the Auditory Brainstem of a Mouse Model of Fragile X Syndrome
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  219. Nov 2021
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    Differential impact of Kv8.2 loss on rod and cone signaling and degeneration
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    Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction
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