472 Matching Annotations
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    STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair
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    Biased cell adhesion organizes the Drosophila visual motion integration circuit
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    sciencedirect.com/science/article/pii/S1534580724006385
  4. Nov 2024
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SNARE protein SNAP25 regulates the chloride-transporter KCC2 in neurons
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  6. Oct 2024
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    Mitochondria remodeling during endometrial stromal cell decidualization
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    Dual regulation of IP3 receptors by IP3 and PIP2 controls the transition from local to global Ca2+ signals
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    sciencedirect.com/science/article/pii/S1097276524007421
  9. Sep 2024
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    Impact of O-GlcNAcylation elevation on mitophagy and glia in the dentate gyrus
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    biorxiv.org/content/10.1101/2024.09.19.613771v1
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    Muscle-derived IL-1β regulates EcSOD expression via the NBR1-p62-Nrf2 pathway in muscle during cancer cachexia
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    Extracellular vesicle-mediated trafficking of molecular cues during human brain development
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    sciencedirect.com/science/article/pii/S2211124724011069
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    Intestinal immunity in C. elegans is activated by pathogen effector-triggered aggregation of the guard protein TIR-1 on lysosome-related organelles
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    sciencedirect.com/science/article/pii/S1074761324004126
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    The LMTK1—TBC1D9B—Rab11A cascade regulates dendritic spine formation via endosome trafficking
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    Functional Regeneration of the Sensory Root via Axonal Invasion
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    Clearing the JUNQ: the molecular machinery for sequestration, localization, and degradation of the JUNQ compartment
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    Spastin regulates ER-mitochondrial contact sites and mitochondrial homeostasis
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    The function of juvenile–adult transition axis in female sexual receptivity of Drosophila melanogaster
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    TGF-β and RAS jointly unmask primed enhancers to drive metastasis
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    Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy
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    Thyroid hormone remodels cortex to coordinate body-wide metabolism and exploration
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    Non-canonical function of ADAM10 in presynaptic plasticity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11335265/
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    Astrocyte Gi-GPCR signaling corrects compulsive-like grooming and anxiety-related behaviors in Sapap3 knockout mice
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    sciencedirect.com/science/article/pii/S0896627324005415
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    Acetate enables metabolic fitness and cognitive performance during sleep disruption
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    sciencedirect.com/science/article/pii/S1550413124002900
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    The divergent effects of G3BP orthologs on human stress granule assembly imply a centric role for the core protein interaction network
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    sciencedirect.com/science/article/pii/S2211124724009677
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    Protocol to establish a demyelinated animal model to study hippocampal neurogenesis and cognitive function in adult rodents
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    sciencedirect.com/science/article/pii/S2666166724004076
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    A multidimensional atlas of human glioblastoma-like organoids reveals highly coordinated molecular networks and effective drugs
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    SERINC proteins potentiate antiviral type I IFN production and proinflammatory signaling pathways
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    Phosphorylation of H3-Thr3 by Haspin Is Required for Primary Cilia Regulation
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  31. Jul 2024
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    Social play behavior is driven by glycine-dependent mechanisms
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    Modulation of a critical period for motor development in Drosophila by BK potassium channels
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    Very long-chain fatty acids control peroxisome dynamics via a feedback loop in intestinal stem cells during gut regeneration
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    sciencedirect.com/science/article/pii/S1534580724003988
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    pLxIS-containing domains are biochemically flexible regulators of interferons and metabolism
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    Piezo regulates epithelial topology and promotes precision in organ size control
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    The SASP factor IL-6 sustains cell-autonomous senescent cells via a cGAS-STING-NFκB intracrine senescent noncanonical pathway
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      DOI: 10.1111/acel.14258

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    onlinelibrary.wiley.com/doi/10.1111/acel.14258
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    Establishment of an iPSC line from a NDD patient with a heterozygous mutation in the CTNNB1 gene
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    sciencedirect.com/science/article/pii/S1873506124001855
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    A REM-active basal ganglia circuit that regulates anxiety
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    sciencedirect.com/science/article/pii/S0960982224007620
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    A transient transcriptional activation governs unpolarized-to-polarized morphogenesis during embryo implantation
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  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterising replisome disassembly in human cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11269944/
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    The versatile binding landscape of the TAAR1 pocket for LSD and other antipsychotic drug molecules
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    sciencedirect.com/science/article/pii/S2211124724008349
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GLOMERULUS-SELECTIVE REGULATION OF A CRITICAL PERIOD FOR INTERNEURON PLASTICITY IN THE DROSOPHILA ANTENNAL LOBE
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      DOI: 10.1523/JNEUROSCI.2192-19.2020

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    ncbi.nlm.nih.gov/pmc/articles/PMC7363474/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KRAP regulates mitochondrial Ca2+ uptake by licensing IP3 receptor activity and stabilizing ER–mitochondrial junctions
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      DOI: 10.1242/jcs.261728

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    ncbi.nlm.nih.gov/pmc/articles/PMC11234384/
  45. Jun 2024
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Substrate mechanics unveil early structural and functional pathology in iPSC micro-tissue models of hypertrophic cardiomyopathy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11141149/
  47. 52.53.155.43 52.53.155.43
    elife-92755-v2-html.html
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      DOI: 10.7554/elife.92755

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    Adrenal Abcg1 controls cholesterol flux and steroidogenesis
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  91. Jan 2024
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    EXO1 protects BRCA1-deficient cells against toxic DNA lesions
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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid β aggregates in vivo in a mouse model of Alzheimer’s disease
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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interaction of PINK1 with nucleotides and kinetin
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    Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk
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    Predicting gene-level sensitivity to JAK-STAT signaling perturbation using a mechanistic-to-machine learning framework
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    Two-Step Actions of Testicular Androgens in the Organization of a Male-Specific Neural Pathway from the Medial Preoptic Area to the Ventral Tegmental Area for Modulating Sexually Motivated Behavior
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  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ULK phosphorylation of STX17 controls autophagosome maturation via FLNA
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  99. Dec 2023
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    Cortical circuitry mediating interareal touch signal amplification
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    Genome-wide study reveals novel roles for formin-2 in axon regeneration as a microtubule dynamics regulator and therapeutic target for nerve repair
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    HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function
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    Mucosal and systemic antigen-specific antibody responses correlate with protection against active tuberculosis in nonhuman primates
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    Eclosion muscles secrete ecdysteroids to initiate asymmetric intestinal stem cell division in Drosophila
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    Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy
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    Hypoxia potentiates the inflammatory fibroblast phenotype promoted by pancreatic cancer cell-derived cytokines
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    Generation of an NSD2-deficient human embryonic stem cell line using CRISPR/Cas9 technology
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  111. Nov 2023
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    Transcription factor NFYa controls cardiomyocyte metabolism and proliferation during mouse fetal heart development
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    Structural and signaling mechanisms of TAAR1 enabled preferential agonist design
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    Systemic and intrinsic functions of ATRX in glial cell fate and CNS myelination in male mice
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    GABAergic-like dopamine synapses in the brain
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    The roles of the native cell differentiation program aberrantly recapitulated in Drosophila intestinal tumors
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    Piezo regulates epithelial topology and promotes precision in organ size control
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    Epithelial restitution in 3D - Revealing biomechanical and physiochemical dynamics in intestinal organoids via fs laser nanosurgery
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    Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8
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    Towards modular engineering of cell signalling: Topographically-textured microparticles induce osteogenesis via activation of canonical hedgehog signalling
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    High-throughput identification of Toxoplasma gondii effector proteins that target host cell transcription
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    DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C
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    Linear ubiquitination at damaged lysosomes induces local NF-κB activation and controls cell survival
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    Review Commons Transfer: Schwann cells are axo-protective after injury irrespective of myelination status in mouse Schwann cell–neuron cocultures
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    Unannotated microprotein EMBOW regulates the interactome and chromatin and mitotic functions of WDR5
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    Establishment of heterozygous and homozygous SHANK3 knockout clonal pluripotent stem cells from the parental hESC line SA001 using CRISPR/Cas9
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    Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
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    A subclass of evening cells promotes the switch from arousal to sleep at dusk
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    Organization of Purkinje cell development by neuronal MEGF11 in cerebellar granule cells
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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTT (huntingtin) and RAB7 co-migrate retrogradely on a signaling LAMP1-containing late endosome during axonal injury
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  135. Aug 2023
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    Social recognition memory differences between mouse strains: On the effects of social isolation, adult neurogenesis, and environmental enrichment
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    Pleiotrophin ameliorates age-induced adult hippocampal neurogenesis decline and cognitive dysfunction
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    Chaperone-mediated autophagy in neuronal dendrites utilizes activity-dependent lysosomal exocytosis for protein disposal
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    Heroin Self-Administration and Extinction Increase Prelimbic Cortical Astrocyte–Synapse Proximity and Alter Dendritic Spine Morphometrics That Are Reversed by N-Acetylcysteine
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  140. Jul 2023
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    A Proximity Labeling Strategy Enables Proteomic Analysis of Inter-organelle Membrane Contacts
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    Synaptotagmin-1-dependent phasic axonal dopamine release is dispensable for basic motor behaviors in mice
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    Centrosome amplification fine tunes tubulin acetylation to differentially control intracellular organization
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    Generation of vascularized human cardiac organoids for 3D in vitro modeling
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    Super-resolution imaging unveils the self-replication of tau aggregates upon seeding
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  146. Jun 2023
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    The Rho1 GTPase controls anillo-septin assembly to facilitate contractile ring closure during cytokinesis
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    Convergence of multiple RNA-silencing pathways on GW182/TNRC6
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    Spd-2 gene duplication reveals cell-type-specific pericentriolar material regulation
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    Golgi satellites are essential for polysialylation of NCAM and expression of LTP at distal synapses
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    FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics
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    CRISPR/Cas9-mediated generation of human embryonic stem cell sub-lines with HPRT1 gene knockout to model Lesch Nyhan disease
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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The septate junction component bark beetle is required for Drosophila intestinal barrier function and homeostasis
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    LRP12 is an endogenous transmembrane inactivator of α4 integrins
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    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
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    Vaccine elicitation and structural basis for antibody protection against alphaviruses
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    Biofilm formation on human immune cells is a multicellular predation strategy of Vibrio cholerae
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    LZTR1 mutation mediates oncogenesis through stabilization of EGFR and AXL
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    Asynchronous transcription and translation of neurotransmitter-related genes characterize the initial stages of neuronal maturation in Drosophila
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    The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins
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    Irisin acts through its integrin receptor in a two-step process involving extracellular Hsp90α
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    Pharyngeal Mechanosensory Neurons Control Food Swallow in Drosophila melanogaster
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    Medulloblastoma and high-grade glioma organoids for drug screening, lineage tracing, co-culture and in vivo assay
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  164. May 2023
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    Distinct axo-protective and axo-destructive roles for Schwann cells after injury in a novel compartmentalised mouse myelinating coculture system
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    Phospholipid scramblase Xkr8 is required for developmental axon pruning via phosphatidylserine exposure
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    Unconventional initiation of PINK1/Parkin mitophagy by Optineurin
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    Upregulated GIRK2 counteracts ethanol-induced changes in excitability and respiration in human neurons
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  169. Apr 2023
  170. www.sciencedirect.com www.sciencedirect.com
    Vascular cells improve functionality of human cardiac organoids
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    Columnar neurons support saccadic bar tracking in Drosophila
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    Nucleation and Dissolution Mechanism Underlying ALS/FTLD-linked FUS Condensates
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    Gαs slow conformational transition upon GTP binding and a novel Gαs regulator
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    Exercise training remodels inguinal white adipose tissue through adaptations in innervation, vascularization, and the extracellular matrix
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    Circadian protein TIMELESS regulates synaptic function and memory by modulating cAMP signaling
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  176. Mar 2023
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    Nuclease activity of Plasmodium falciparum Alba family protein PfAlba3
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic dissection of mutual interference between two consecutive learning tasks in Drosophila
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  179. www.biorxiv.org www.biorxiv.org
    Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid β aggregates in vivo in a mouse model of Alzheimer’s disease
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    A hydraulic feedback loop between mesendoderm cell migration and interstitial fluid relocalization promotes embryonic axis formation in zebrafish
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    Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene induction
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    Bone marrow Adipoq-lineage progenitors are a major cellular source of M-CSF that dominates bone marrow macrophage development, osteoclastogenesis, and bone mass
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    Real-time mechanisms of exacerbated synaptic remodeling by microglia in acute models of systemic inflammation and tauopathy
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    Tumor suppressor p53 regulates heat shock factor 1 protein degradation in Huntington’s disease
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bacillus thuringiensis toxins divert progenitor cells toward enteroendocrine fate by decreasing cell adhesion with intestinal stem cells in Drosophila
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  186. Feb 2023
  187. 52.53.155.43 52.53.155.43
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    GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
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    3D human induced pluripotent stem cell–derived bioengineered skeletal muscles for tissue, disease and therapy modeling
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    Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules
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  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A dedicate sensorimotor circuit enables fine texture discrimination by active touch
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  192. Jan 2023
  193. www.sciencedirect.com www.sciencedirect.com
    Behavioral state-dependent modulation of insulin-producing cells in Drosophila
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    A novel period mutation implicating nuclear export in temperature compensation of the Drosophila circadian clock
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  195. www.nature.com www.nature.com
    Annelid functional genomics reveal the origins of bilaterian life cycles
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    Characterization of the structure and control of the blood-nerve barrier identifies avenues for therapeutic delivery
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    CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performance
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    Distinct niche structures and intrinsic programs of fallopian tube and ovarian surface epithelial cells
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  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice
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  200. Dec 2022
  201. link.springer.com link.springer.com
    The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities
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    Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis
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    In vitro-derived medium spiny neurons recapitulate human striatal development and complexity at single-cell resolution
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    Structurally distinct PARP7 inhibitors provide new insights into the function of PARP7 in regulating nucleic acid-sensing and IFN-β signaling
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    USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
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  206. Nov 2022
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    Generation of a homozygous FIS1 knockout human embryonic stem cell line GIBHe015-B by CRISPR/Cas9 system
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    A novel function for the sperm adhesion protein IZUMO1 in cell–cell fusion
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    Antiviral function and viral antagonism of the rapidly evolving dynein activating adaptor NINL
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    Membrane phosphoinositides regulate GPCR-β-arrestin complex assembly and dynamics
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    Physical confinement promotes mesenchymal trans-differentiation of invading transformed cells in vivo
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    HIV-1 Vpu restricts Fc-mediated effector functions in vivo
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    Dual anti-angiogenic and anti-metastatic activity of myriocin synergistically enhances the anti-tumor activity of cisplatin
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  214. Oct 2022
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    Identification of proteomic landscape of drug-binding proteins in live cells by proximity-dependent target ID
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  216. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sleep need-dependent changes in functional connectivity facilitate transmission of homeostatic sleep drive
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  217. Sep 2022
  218. www.sciencedirect.com www.sciencedirect.com
    A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration
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    Photoreceptors generate neuronal diversity in their target field through a Hedgehog morphogen gradient in Drosophila
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      DOI: 10.7554/eLife.78093

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