275 Matching Annotations
  1. Last 7 days
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    Accumulation of APP C-terminal fragments causes endolysosomal dysfunction through the dysregulation of late endosome to lysosome-ER contact sites
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    sciencedirect.com/science/article/pii/S1534580724001990
  3. Apr 2024
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    “Heterogeneous subpopulations of GABAAR-responding neurons coexist across neuronal networks scales and developmental stages in health and disease”
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    ncbi.nlm.nih.gov/pmc/articles/PMC10966311/
  5. Mar 2024
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    The RNA binding proteins LARP4A and LARP4B promote sarcoma and carcinoma growth and metastasis
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  7. rupress.org rupress.org
    Medioapical contractile pulses coordinated between cells regulate Drosophila eye morphogenesis
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    Type-I-interferon-responsive microglia shape cortical development and behavior
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    sciencedirect.com/science/article/pii/S0092867424001867
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    Collective cell migration relies on PPP1R15-mediated regulation of the endoplasmic reticulum stress response
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    sciencedirect.com/science/article/pii/S0960982224001568
  10. Feb 2024
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    EHBP1 is critically involved in dendritic arbor formation and is coupled to factors promoting actin filament formation
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    Akt3 activation by R-Ras in an endothelial cell enforces quiescence and barrier stability of neighboring endothelial cells via Jagged1
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    sciencedirect.com/science/article/pii/S2211124724001657
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    Mouse oocytes sequester aggregated proteins in degradative super-organelles
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    Establishment of induced pluripotent stem cell lines derived from Parkinson’s disease Mexican patients: A sporadic (UNAMi002-A) and a familial (UNAMi003-A) case carrying a mutation in PINK1
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    sciencedirect.com/science/article/pii/S1873506124000357
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    Dual roles of CCDC102A in governing centrosome duplication and cohesion
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  16. Jan 2024
  17. www.science.org www.science.org
    Integration of reconfigurable microchannels into aligned three-dimensional neural networks for spatially controllable neuromodulation
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    Multiple reorganizations of the lateral elements of the synaptonemal complex facilitate homolog segregation in Bombyx mori oocytes
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    sciencedirect.com/science/article/pii/S0960982223016731
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    Dynamic palmitoylation of STX11 controls injury-induced fatty acid uptake to promote muscle regeneration
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    Cytoneme signaling provides essential contributions to mammalian tissue patterning
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  21. Dec 2023
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    Kremen1 regulates the regenerative capacity of support cells and mechanosensory hair cells in the zebrafish lateral line
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    sciencedirect.com/science/article/pii/S2589004223027554
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    Nutrient-regulated control of lysosome function by signaling lipid conversion
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    sciencedirect.com/science/article/pii/S0092867423010814
  24. Nov 2023
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    Mapping of neuronal and glial primary cilia contactome and connectome in the human cerebral cortex
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    sciencedirect.com/science/article/abs/pii/S0896627323007195
  26. Oct 2023
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    An activity-based functional test for identifying homologous recombination deficiencies across cancer types in real time
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    sciencedirect.com/science/article/pii/S266637912300424X
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deep learning enables STORM-like superresolution image reconstruction from conventional microscopy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10587619/
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    α-Synuclein-dependent increases in PIP5K1γ drive inositol signaling to promote neurotoxicity
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    sciencedirect.com/science/article/pii/S2211124723012561
  30. www.cell.com www.cell.com
    GABAergic signaling shapes multiple aspects of Drosophila courtship motor behavior
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    cell.com/iscience/abstract/S2589-0042(23)02146-6
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conditional knockdown protocol for studying cellular communication using Drosophila melanogaster wing imaginal disc
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    Dendritic distribution of autophagosomes underlies pathway-selective induction of LTD
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    ncbi.nlm.nih.gov/pmc/articles/PMC10528062/
  33. Sep 2023
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    Hunger- and thirst-sensing neurons modulate a neuroendocrine network to coordinate sugar and water ingestion
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      DOI: 10.7554/eLife.88143

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    Zebrafish functional xenograft vasculature platform identifies PF-502 as a durable vasculature normalization drug
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    ncbi.nlm.nih.gov/pmc/articles/PMC10480778/
  36. Aug 2023
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    Cell-type-specific plasticity shapes neocortical dynamics for motor learning
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    The effects of the NMDAR co-agonist d-serine on the structure and function of optic tectal neurons in the developing visual system
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      DOI: 10.1038/s41598-023-39951-4

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    Chaperone-mediated autophagy in neuronal dendrites utilizes activity-dependent lysosomal exocytosis for protein disposal
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    sciencedirect.com/science/article/pii/S2211124723010094
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    Senescent cells form nuclear foci that contain the 26S proteasome
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    sciencedirect.com/science/article/pii/S2211124723008914
  41. Jul 2023
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    Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens
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  43. 52.53.155.43 52.53.155.43
    A dual hit of α-synuclein internalization and immune challenge leads to formation and maintenance of Lewy body-like inclusions in human dopaminergic neurons
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    Chromatin regulation of transcriptional enhancers and cell fate by the Sotos syndrome gene NSD1
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    sciencedirect.com/science/article/pii/S1097276523004306
  45. Jun 2023
  46. www.embopress.org www.embopress.org
    A phylogenetic profiling approach identifies novel ciliogenesis genes in Drosophila and C. elegans
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      DOI: 10.15252/embj.2023113616

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    embopress.org/doi/10.15252/embj.2023113616
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    Input density tunes Kenyon cell sensory responses in the Drosophila mushroom body
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    sciencedirect.com/science/article/pii/S0960982223007364
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    Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination
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    Deneddylating enzyme SENP8 regulates neuronal development
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      DOI: 10.1111/jnc.15797

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15797
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mating activates neuroendocrine pathways signaling hunger in Drosophila females
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      DOI: 10.7554/eLife.85117

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    ncbi.nlm.nih.gov/pmc/articles/PMC10229122/
  51. May 2023
  52. www.sciencedirect.com www.sciencedirect.com
    The ultrastructural function of MLN64 in the late endosome–mitochondria membrane contact sites in placental cells
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    The adhesion GPCRs CELSR1–3 and LPHN3 engage G proteins via distinct activation mechanisms
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    Assessment of drug permeability through an ex vivo porcine round window membrane model
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    Table 3 Antibodies
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    Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex
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    Glial progenitor heterogeneity and key regulators revealed by single-cell RNA sequencing provide insight to regeneration in spinal cord injury
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    Neural circuit mechanisms linking courtship and reward in Drosophila males
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    A tubule-sheet continuum model for the mechanism of nuclear envelope assembly
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    Piezo-mediated mechanosensation contributes to stabilizing copulation posture and reproductive success in Drosophila males
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    Coordination of tissue homeostasis and growth by the Scribble-α-Catenin-Septate junction complex
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    Asymmetric mechanotransduction by hair cells of the zebrafish lateral line
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    Coronavirus Subverts ER-phagy by Hijacking FAM134B and ATL3 into p62 Condensates to Facilitate Viral Replication
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    In situ microwave fixation provides an instantaneous snapshot of the brain metabolome
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    Decoding the molecular crosstalk between grafted stem cells and the stroke-injured brain
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    Optineurin provides a mitophagy contact site for TBK1 activation
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    Ablation of palladin in adult heart causes dilated cardiomyopathy associated with intercalated disc abnormalities
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    SOCS1 regulates a subset of NFκB-target genes through direct chromatin binding and defines macrophage functional phenotypes.
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    A cingulate-hippocampal circuit mediates early depressive symptoms in Alzheimer’s disease
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  71. Mar 2023
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    Ribosome-rescuer PELO catalyzes the oligomeric assembly of NOD-like receptor family proteins via activating their ATPase enzymatic activity
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    Physical exercise modulates the microglial complement pathway in mice to relieve cortical circuitry deficits induced by mutant human TDP-43
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    Integration of reconfigurable microchannels into aligned three-dimensional neural networks for spatially controllable neuromodulation
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    Simultaneous activation of Tor and suppression of ribosome biogenesis by TRIM-NHL proteins promotes terminal differentiation
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    The proteome and transcriptome of stress granules and P bodies during human T lymphocyte activation
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    Activation of β-catenin in mesenchymal progenitors leads to muscle mass loss
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    H2-induced transient upregulation of phospholipids with suppression of energy metabolism
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    Kaurenoic Acid Reduces Ongoing Chronic Constriction Injury-Induced Neuropathic Pain: Nitric Oxide Silencing of Dorsal Root Ganglia Neurons
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    EndophilinA-dependent coupling between activity-induced calcium influx and synaptic autophagy is disrupted by a Parkinson-risk mutation
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    Voluntary running exercise modifies astrocytic population and features in the peri-infarct cortex
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    SREBP modulates the NADP+/NADPH cycle to control night sleep in Drosophila
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    Mutations in Parkinsonism-linked endocytic proteins synaptojanin1 and auxilin have synergistic effects on dopaminergic axonal pathology
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    Microtubule nucleation from the fibrous corona by LIC1-pericentrin promotes chromosome congression
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    Excitation-inhibition imbalance disrupts visual familiarity in amyloid and non-pathology conditions
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    Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient
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    Dynamics of endogenous PARP1 and PARP2 during DNA damage revealed by live-cell single-molecule imaging
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    Resolvin D5 (RvD5) Reduces Renal Damage Caused by LPS Endotoxemia in Female Mice
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    The Golgi-resident protein ACBD3 concentrates STING at ER-Golgi contact sites to drive export from the ER
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    Preferential arborization of dendrites and axons of parvalbumin- and somatostatin-positive GABAergic neurons within subregions of the mouse claustrum
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    Super-resolution microscopy reveals nanoscale architecture and regulation of podosome clusters in primary macrophages
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    Atg1 modulates mitochondrial dynamics to promote germline stem cell maintenance in Drosophila
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  97. Nov 2022
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  111. Jun 2022
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    Drosophila gustatory projections are segregated by taste modality and connectivity
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    Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer’s disease risk factor CALM bidirectionally controls synaptic plasticity
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    Plasmodium parasitophorous vacuole membrane-resident protein UIS4 manipulates host cell actin to avoid parasite elimination
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  120. Apr 2022
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    A Conditioned Place Preference for Heroin Is Signaled by Increased Dopamine and Direct Pathway Activity and Decreased Indirect Pathway Activity in the Nucleus Accumbens
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  124. Mar 2022
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  132. Feb 2022
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    Systematic mapping of nuclear domain-associated transcripts reveals speckles and lamina as hubs of functionally distinct retained introns
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    Naegleria’s mitotic spindles are built from unique tubulins and highlight core spindle features
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    R-type voltage-gated Ca2+ channels mediate A-type K+ current regulation of synaptic input in hippocampal dendrites
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  142. Dec 2021
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  144. Nov 2021
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  147. Oct 2021
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    Adult stem cells and niche cells segregate gradually from common precursors that build the adult Drosophila ovary during pupal development
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  151. Sep 2021
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    EAAT2 Expression in the Hippocampus, Subiculum, Entorhinal Cortex and Superior Temporal Gyrus in Alzheimer’s Disease
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    Experience-dependent myelination following stress is mediated by the neuropeptide dynorphin
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    An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens
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    Generation of an hiPSC-1 knock-in line expressing TY1-tagged MNX1-protein together with mScarlet
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  158. Aug 2021
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    Stimulus Feature-Specific Control of Layer 2/3 Subthreshold Whisker Responses by Layer 4 in the Mouse Primary Somatosensory Cortex
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    The 3D architecture and molecular foundations of de novo centriole assembly via bicentrioles
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    Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors
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    Morphological properties of the axon initial segment-like process of AII amacrine cells in the rat retina
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    Pupal behavior emerges from unstructured muscle activity in response to neuromodulation in Drosophila
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    Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage
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  172. Jul 2021
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    17α Estradiol promotes plasticity of spared inputs in the adult amblyopic visual cortex
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    A toolbox of nanobodies developed and validated for use as intrabodies and nanoscale immunolabels in brain neurons
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    Semaphorin 2b Regulates Sleep-Circuit Formation in the Drosophila Central Brain
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    Dynamic Palmitoylation Targets MAP6 to the Axon to Promote Microtubule Stabilization during Neuronal Polarization
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    Four of the six Drosophila rhodopsin‐expressing photoreceptors can mediate circadian entrainment in low light
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    KChIP2 is a core transcriptional regulator of cardiac excitability
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    Dpp dependent Hematopoietic stem cells give rise to Hh dependent blood progenitors in larval lymph gland of Drosophila
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    Striatal low-threshold spiking interneurons locally gate dopamine
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    Functional interdependence of the actin nucleator Cobl and Cobl-like in dendritic arbor development
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    Sustained treatment with an α5 GABA A receptor negative allosteric modulator delays excitatory circuit development while maintaining GABAergic neurotransmission
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    NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism
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    A protocol for representative sampling of solid tumors to improve the accuracy of sequencing results
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  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Arhgef2 regulates neural differentiation in the cerebral cortex through mRNA m6A-methylation of Npdc1 and Cend1
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  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Individual B cells transcribe multiple rearranged immunoglobulin light chains in teleost fish
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  195. elifesciences.org elifesciences.org
    Dopamine differentially modulates the size of projection neuron ensembles in the intact and dopamine-depleted striatum
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  196. www.nature.com www.nature.com
    The SUN1-SPDYA interaction plays an essential role in meiosis prophase I
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  197. May 2021
  198. www.embopress.org www.embopress.org
    NPC1 regulates the distribution of phosphatidylinositol 4-kinases at Golgi and lysosomal membranes
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  199. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Phosphorylation of Collapsin Response Mediator Protein 1 (CRMP1) at Tyrosine 504 residue regulates Semaphorin 3A-induced cortical dendritic growth
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      647- labeled Goat anti-mouse IgG

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    Disease-causing mutated ATLASTIN 3 is excluded from distal axons and reduces axonal autophagy
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    Apical intercalated cell cluster: A distinct sensory regulator in the amygdala
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    VEGF counteracts amyloid-β-induced synaptic dysfunction
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    G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD
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    Two Brain Pathways Initiate Distinct Forward Walking Programs in Drosophila
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    Loss of TAX1BP1-Directed Autophagy Results in Protein Aggregate Accumulation in the Brain
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    Filopodium-derived vesicles produced by MIM enhance the migration of recipient cells
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    Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains
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    Mitotic ER Exit Site Disassembly and Reassembly Are Regulated by the Phosphorylation Status of TANGO1
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  209. Apr 2021
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    Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons
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    Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C
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    Immunogenomic Landscape of Hematological Malignancies
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  213. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endoplasmic reticulum oxidoreductase 1 alpha modulates prostate cancer hallmarks
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  214. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Modulating local S1P receptor signaling as a regenerative immunotherapy after volumetric muscle loss injury
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    The mechanistic basis of protection by non-neutralizing anti-alphavirus antibodies
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    A well plate–based multiplexed platform for incorporation of organoids into an organ-on-a-chip system with a perfusable vasculature
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    Neddylation is required for presynaptic clustering of mGlu7 and maturation of presynaptic terminals
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  218. Mar 2021
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    Astrocyte-derived small extracellular vesicles promote synapse formation via fibulin-2-mediated TGF-β signaling
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    Ppargc1a Controls Ciliated Cell Development by Regulating Prostaglandin Biosynthesis
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    Comparative Cell Surface Proteomic Analysis of the Primary Human T Cell and Monocyte Responses to Type I Interferon
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    ER-directed TREX1 limits cGAS activation at micronuclei
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    Recombinant human growth hormone activates neuroprotective growth factors in hypoxic brain injury in neonatal mice
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  224. Feb 2021
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    Activation of MAP3K DLK and LZK in Purkinje cells causes rapid and slow degeneration depending on signaling strength
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    A switch in pdgfrb+ cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord
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    The Interplay Between Beta-Amyloid 1–42 (Aβ1–42)-Induced Hippocampal Inflammatory Response, p-tau, Vascular Pathology, and Their Synergistic Contributions to Neuronal Death and Behavioral Deficits
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    Combined kinesin-1 and kinesin-3 activity drives axonal trafficking of TrkB receptors in Rab6 carriers
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    Ctdnep1 and Eps8L2 regulate dorsal actin cables for nuclear positioning during cell migration
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  230. Jan 2021
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    Small Molecule SARM1 Inhibitors Recapitulate the SARM1−/− Phenotype and Allow Recovery of a Metastable Pool of Axons Fated to Degenerate
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  232. Dec 2020
  233. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytosolic calcium regulates cytoplasmic accumulation of TDP-43 through Calpain-A and Importin α3
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  234. www.cell.com www.cell.com
    Sensory Discrimination of Blood and Floral Nectar by Aedes aegypti Mosquitoes
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      Goat anti-mouse Alexa Fluor 647

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    Survival and Motor Phenotypes in FVB C9-500 ALS/FTD BAC Transgenic Mice Reproduced by Multiple Labs
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  236. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    3D in situ imaging of the female reproductive tract reveals molecular signatures of fertilizing spermatozoa in mice
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