105 Matching Annotations
  1. May 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The action mechanism by which C1q/tumor necrosis factor-related protein-6 alleviates cerebral ischemia/reperfusion injury in diabetic mice
    1
    1. scibot 01 May 2024
      RRID:AB_2536530

      DOI: 10.4103/1673-5374.390951

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    ncbi.nlm.nih.gov/pmc/articles/PMC11040306/
  3. Mar 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness
    3
    1. scibot 15 Mar 2024
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      DOI: 10.1016/j.ccell.2024.02.016

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    2. scibot 15 Mar 2024
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      DOI: 10.1016/j.ccell.2024.02.016

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    3. scibot 15 Mar 2024
      RRID:AB_2536530

      DOI: 10.1016/j.ccell.2024.02.016

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    sciencedirect.com/science/article/pii/S1535610824000606
  5. Feb 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Heat stress promotes Arabidopsis AGO1 phase separation and association with stress granule components
    2
    1. scibot 29 Feb 2024
      RRID:AB_2536530

      DOI: 10.1016/j.isci.2024.109151

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    2. scibot 28 Feb 2024
      RRID:AB_2536530

      DOI: 10.1016/j.isci.2024.109151

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    sciencedirect.com/science/article/pii/S2589004224003729
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A small-molecule degrader selectively inhibits the growth of ALK-rearranged lung cancer with ceritinib resistance
    1
    1. scibot 10 Feb 2024
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      DOI: 10.1016/j.isci.2024.109015

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    ncbi.nlm.nih.gov/pmc/articles/PMC10847737/
  8. Jan 2024
  9. www.sciencedirect.com www.sciencedirect.com
    ABCG2 is an itaconate exporter that limits antibacterial innate immunity by alleviating TFEB-dependent lysosomal biogenesis
    1
    1. scibot 11 Jan 2024
      RRID:AB_2536530

      DOI: 10.1016/j.cmet.2023.12.015

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    sciencedirect.com/science/article/pii/S1550413123004655
  10. www.sciencedirect.com www.sciencedirect.com
    Dynamic IL-6R/STAT3 signaling leads to heterogeneity of metabolic phenotype in pancreatic ductal adenocarcinoma cells
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113612

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    sciencedirect.com/science/article/pii/S2211124723016248
  11. Dec 2023
  12. www.sciencedirect.com www.sciencedirect.com
    Phosphoprotein dynamics of interacting T cells and tumor cells by HySic
    1
    1. scibot 29 Dec 2023
      RRID:AB_2536530

      DOI: 10.1016/j.celrep.2023.113598

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    sciencedirect.com/science/article/pii/S2211124723016108
  13. Sep 2023
  14. www.sciencedirect.com www.sciencedirect.com
    Stress response mechanisms in protein misfolding diseases: Profiling a cellular model of Huntington's disease
    1
    1. scibot 19 Sep 2023
      RRID:AB_2536530

      DOI: 10.1016/j.abb.2023.109711

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    sciencedirect.com/science/article/pii/S0003986123002102
  15. Aug 2023
  16. www.sciencedirect.com www.sciencedirect.com
    Functional analogs of mammalian 4E-BPs reveal a role for TOR in global plant translation
    1
    1. scibot 03 Aug 2023
      RRID:AB_2536530

      DOI: 10.1016/j.celrep.2023.112892

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    sciencedirect.com/science/article/pii/S2211124723009038
  17. Jul 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Disruption of neuronal RHEB signaling impairs oligodendrocyte differentiation and myelination through mTORC1-DLK1 axis
    1
    1. scibot 21 Jul 2023
      RRID:AB_2536530

      DOI: 10.1016/j.celrep.2023.112801

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    sciencedirect.com/science/article/pii/S2211124723008124
  19. www.sciencedirect.com www.sciencedirect.com
    The kinesin Kif21b regulates radial migration of cortical projection neurons through a non-canonical function on actin cytoskeleton
    1
    1. scibot 07 Jul 2023
      RRID:AB_2536530

      DOI: 10.1016/j.celrep.2023.112744

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    sciencedirect.com/science/article/pii/S2211124723007556
  20. Jun 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Generation of two edited iPSCs lines by CRISPR/Cas9 with point mutations in PKP2 gene for Arrhythmogenic Cardiomyopathy in vitro modeling
    1
    1. scibot 28 Jun 2023
      RRID:AB_2536530

      DOI: 10.1016/j.scr.2023.103157

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    sciencedirect.com/science/article/pii/S1873506123001435
  22. May 2023
  23. www.sciencedirect.com www.sciencedirect.com
    RBM33 is a unique m6A RNA-binding protein that regulates ALKBH5 demethylase activity and substrate selectivity
    1
    1. scibot 31 May 2023
      RRID:AB_2536530

      DOI: 10.1016/j.molcel.2023.05.010

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    sciencedirect.com/science/article/pii/S1097276523003349
  24. www.sciencedirect.com www.sciencedirect.com
    Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR
    1
    1. scibot 05 May 2023
      RRID:AB_2536530

      DOI: 10.1016/j.celrep.2022.111092

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    sciencedirect.com/science/article/pii/S2211124722008944
  25. Apr 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial dynamics define muscle fiber type by modulating cellular metabolic pathways
    1
    1. scibot 26 Apr 2023
      RRID:AB_2536530

      DOI: 10.1016/j.celrep.2023.112434

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    sciencedirect.com/science/article/pii/S221112472300445X
  27. www.sciencedirect.com www.sciencedirect.com
    Cell-type-specific responses to the microbiota across all tissues of the larval zebrafish
    1
    1. scibot 19 Apr 2023
      RRID:AB_2536530

      DOI: 10.1016/j.celrep.2023.112095

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    sciencedirect.com/science/article/pii/S2211124723001067
  28. Mar 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FDA-approved Abl/EGFR/PDGFR kinase inhibitors show potent efficacy against pandemic and seasonal influenza A virus infections of human lung explants
    1
    1. scibot 26 Mar 2023
      RRID:AB_2536530

      DOI: 10.1016/j.isci.2023.106309

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    ncbi.nlm.nih.gov/pmc/articles/PMC10034449/
  30. Jan 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Single-copy locus proteomics of early- and late-firing DNA replication origins identifies a role of Ask1/DASH complex in replication timing control
    1
    1. scibot 27 Jan 2023
      RRID:AB_2536530

      DOI: 10.1016/j.celrep.2023.112045

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    sciencedirect.com/science/article/pii/S2211124723000566
  32. www.sciencedirect.com www.sciencedirect.com
    Genetic screens reveal new targetable vulnerabilities in BAP1-deficient mesothelioma
    1
    1. scibot 19 Jan 2023
      RRID:AB_2536530

      DOI: 10.1016/j.xcrm.2022.100915

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    sciencedirect.com/science/article/pii/S2666379122004943
  33. Dec 2022
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low-dose ganciclovir ameliorates dextran sulfate sodium-induced ulcerative colitis through inhibiting macrophage STING activation in mice
    1
    1. scibot 03 Dec 2022
      RRID:AB_2536530

      DOI: 10.3389/fphar.2022.1020670

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    ncbi.nlm.nih.gov/pmc/articles/PMC9714675/
  35. Nov 2022
  36. link.springer.com link.springer.com
    Hyponatremia-related liver steatofibrosis and impaired spermatogenesis: evidence from a mouse model of the syndrome of inappropriate antidiuresis
    1
    1. scibot 29 Nov 2022
      RRID:AB_2536530

      DOI: 10.1007/s40618-022-01962-9

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    link.springer.com/article/10.1007/s40618-022-01962-9
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disrupted control of origin activation compromises genome integrity upon destabilization of Polε and dysfunction of the TRP53-CDKN1A/P21 axis
    1
    1. scibot 19 Nov 2022
      RRID:AB_2536530

      DOI: 10.1016/j.celrep.2022.110871

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    ncbi.nlm.nih.gov/pmc/articles/PMC9637995/
  38. www.sciencedirect.com www.sciencedirect.com
    Intertwined Wdr47-NTD dimer recognizes a basic-helical motif in Camsap proteins for proper central-pair microtubule formation
    1
    1. scibot 10 Nov 2022
      RRID:AB_2536530

      DOI: 10.1016/j.celrep.2022.111589

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    sciencedirect.com/science/article/pii/S2211124722014541
  39. Oct 2022
  40. www.sciencedirect.com www.sciencedirect.com
    Two independent respiratory chains adapt OXPHOS performance to glycolytic switch
    1
    1. scibot 05 Oct 2022
      RRID:AB_2536530

      DOI: 10.1016/j.cmet.2022.09.005

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    sciencedirect.com/science/article/pii/S1550413122003953
  41. Sep 2022
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
    1
    1. scibot 02 Sep 2022
      RRID:AB_2536530

      DOI: 10.1158/2159-8290.CD-21-1077

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    ncbi.nlm.nih.gov/pmc/articles/PMC8904298/
  43. www.sciencedirect.com www.sciencedirect.com
    Convergent cerebrospinal fluid proteomes and metabolic ontologies in humans and animal models of Rett syndrome
    1
    1. scibot 01 Sep 2022
      RRID:AB_2536530

      DOI: 10.1016/j.isci.2022.104966

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    sciencedirect.com/science/article/pii/S258900422201238X
  44. Aug 2022
  45. www.sciencedirect.com www.sciencedirect.com
    APOE4 drives inflammation in human astrocytes via TAGLN3 repression and NF-κB activation
    1
    1. scibot 17 Aug 2022
      RRID:AB_2536530

      DOI: 10.1016/j.celrep.2022.111200

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    sciencedirect.com/science/article/pii/S2211124722010178
  46. Jul 2022
  47. link.springer.com link.springer.com
    Upregulation of Nox4 induces a pro-survival Nrf2 response in cancer-associated fibroblasts that promotes tumorigenesis and metastasis, in part via Birc5 induction
    1
    1. scibot 15 Jul 2022
      RRID:AB_2536530

      DOI: 10.1186/s13058-022-01548-6

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    link.springer.com/article/10.1186/s13058-022-01548-6
  48. May 2022
  49. www.sciencedirect.com www.sciencedirect.com
    All-viral tracing of monosynaptic inputs to single birthdate-defined neurons in the intact brain
    1
    1. scibot 26 May 2022
      RRID:AB_2536530

      DOI: 10.1016/j.crmeth.2022.100221

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    sciencedirect.com/science/article/pii/S2667237522000844
  50. www.sciencedirect.com www.sciencedirect.com
    Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway
    1
    1. scibot 13 May 2022
      RRID:AB_2536530

      DOI: 10.1016/j.celrep.2022.110790

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    sciencedirect.com/science/article/pii/S2211124722005575
  51. Apr 2022
  52. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Serotonin 5-HT7 receptor overexpression in the raphe nuclei area produces antidepressive effect and affects brain serotonin system in male mice
    1
    1. scibot 21 Apr 2022
      RRID:AB_2536530

      DOI: 10.1002/jnr.25055

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    onlinelibrary.wiley.com/doi/10.1002/jnr.25055
  53. www.sciencedirect.com www.sciencedirect.com
    The Arabidopsis F-box protein FBW2 targets AGO1 for degradation to prevent spurious loading of illegitimate small RNA
    1
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      RRID:AB_2536530

      DOI: 10.1016/j.celrep.2022.110671

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    sciencedirect.com/science/article/pii/S2211124722004235
  54. www.nature.com www.nature.com
    Genetic instability from a single S phase after whole-genome duplication
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      RRID:AB_2536530

      DOI: 10.1038/s41586-022-04578-4

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    nature.com/articles/s41586-022-04578-4
  55. elifesciences.org elifesciences.org
    Evolutionary conservation of centriole rotational asymmetry in the human centrosome
    1
    1. scibot 07 Apr 2022
      RRID:AB_2536530

      DOI: 10.7554/eLife.72382

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    elifesciences.org/articles/72382
  56. Mar 2022
  57. www.sciencedirect.com www.sciencedirect.com
    Fungal sensing enhances neutrophil metabolic fitness by regulating antifungal Glut1 activity
    1
    1. scibot 26 Mar 2022
      RRID:AB_2536530

      DOI: 10.1016/j.chom.2022.02.017

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    sciencedirect.com/science/article/pii/S1931312822001032
  58. Feb 2022
  59. www.sciencedirect.com www.sciencedirect.com
    CASCADE: high-throughput characterization of regulatory complex binding altered by non-coding variants
    2
    1. scibot 11 Feb 2022
      RRID:AB_2536530

      DOI: 10.1016/j.xgen.2022.100098

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    2. scibot 11 Feb 2022
      RRID:AB_2536530

      DOI: 10.1016/j.xgen.2022.100098

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    sciencedirect.com/science/article/pii/S2666979X22000155
  60. www.sciencedirect.com www.sciencedirect.com
    Enhanced immunoprecipitation techniques for the identification of RNA binding protein partners: IGF2BP1 interactions in mammary epithelial cells
    1
    1. scibot 04 Feb 2022
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      DOI: 10.1016/j.jbc.2022.101649

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    A M1 muscarinic acetylcholine receptor positive allosteric modulator improves pathology and cognitive deficits in female APPswe/PSEN1ΔE9 mice
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    Mitochondrial retrograde signaling through UCP1-mediated inhibition of the plant oxygen-sensing pathway
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  63. Dec 2021
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    IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer
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  65. Nov 2021
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    Nde1 is a Rab9 effector for loading late endosomes to cytoplasmic dynein motor complex
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  68. Oct 2021
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    CWI pathway participated in vegetative growth and pathogenicity through a downstream effector AflRlm1 in Aspergillus flavus
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    PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation
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    Nitrate signaling promotes plant growth by upregulating gibberellin biosynthesis and destabilization of DELLA proteins
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    Generation of two gene corrected human isogenic iPSC lines (NCATS-CL6104 and NCATS-CL6105) from a patient line (NCATS-CL6103) carrying a homozygous p.R401X mutation in the NGLY1 gene using CRISPR/Cas9
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  73. Sep 2021
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    Brain adiponectin signaling controls peripheral insulin response in Drosophila
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    SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 to direct pro-inflammatory signaling in TLR-activated macrophages
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  76. Aug 2021
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    HIV-1 Nef interacts with the cyclin K/CDK13 complex to antagonize SERINC5 for optimal viral infectivity
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    miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to impact proteotoxicity and muscle function during aging
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The long non-coding RNA Cerox1 is a post transcriptional regulator of mitochondrial complex I catalytic activity
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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  83. Jul 2021
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    Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo
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    Centromere Dysfunction Compromises Mitotic Spindle Pole Integrity
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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response
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    Retrofusion of intralumenal MVB membranes parallels viral infection and coexists with exosome release
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  89. Jun 2021
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    Generation of genetically modified human induced pluripotent stem cell lines harboring haploinsufficient or dominant negative variants in the FBN1 gene
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  91. May 2021
  92. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Mechanical overload-induced muscle-derived extracellular vesicles promote adipose tissue lipolysis
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      DOI: 10.1096/fj.202100242R

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    Generation of two human induced pluripotent stem cell (hiPSC) lines derived from unrelated Marfan Syndrome patients
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    Axonal generation of amyloid-β from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes
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    HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis
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    Actin-Membrane Release Initiates Cell Protrusions
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  97. Apr 2021
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    Scribble sub-cellular localization modulates recruitment of YES1 to regulate YAP1 phosphorylation
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional interpretation of ATAD3A variants in neuro-mitochondrial phenotypes
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      DOI: 10.1186/s13073-021-00873-3

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  100. Mar 2021
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    The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-Mediated Immune Responses
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  102. Feb 2021
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    JNK signaling regulates oviposition in the malaria vector Anopheles gambiae
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      DOI: 10.1038/s41598-020-71291-5

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  104. Jan 2021
  105. www.sciencedirect.com www.sciencedirect.com
    The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway
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    Establishing a human embryonic stem cell clone with a heterozygous mutation in the DGCR8 gene
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  107. Sep 2020
  108. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Heterogeneity in VEGF Receptor-2 Mobility and Organization on the Endothelial Cell Surface Leads to Diverse Models of Activation by VEGF
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  109. www.eneuro.org www.eneuro.org
    Grp94 regulates the recruitment of aneural AChR clusters for the assembly of postsynaptic specializations by modulating ADF/cofilin activity and turnover
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      DOI: 10.1523/ENEURO.0025-20.2020

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    11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma
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    The Cys-Arg/N-End Rule Pathway Is a General Sensor of Abiotic Stress in Flowering Plants
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      DOI: 10.1016/j.cub.2017.09.006

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    ATF7-Dependent Epigenetic Changes Are Required for the Intergenerational Effect of a Paternal Low-Protein Diet
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      DOI: 10.1016/j.molcel.2020.02.028

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  113. www.sciencedirect.com www.sciencedirect.com
    Butyrophilin-2A1 Directly Binds Germline-Encoded Regions of the Vγ9Vδ2 TCR and Is Essential for Phosphoantigen Sensing
    1
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      RRID:AB_2536530

      DOI: 10.1016/j.immuni.2020.02.014

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  114. www.sciencedirect.com www.sciencedirect.com
    An Insulin-Sensitive Circular RNA that Regulates Lifespan in Drosophila
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      DOI: 10.1016/j.molcel.2020.06.011

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  115. advances.sciencemag.org advances.sciencemag.org
    Emilin 2 promotes the mechanical gradient of the cochlear basilar membrane and resolution of frequencies in sound
    1
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      DOI: 10.1126/sciadv.aba2634

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  116. Aug 2020
  117. journals.physiology.org journals.physiology.org
    Ca2+ dependency of limb muscle fiber contractile mechanics in young and older adults | American Journal of Physiology-Cell Physiology
    1
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      DOI: 10.1152/ajpcell.00575.2019

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  118. Jan 2020
  119. www.sciencedirect.com www.sciencedirect.com
    Differences in Mitotic Spindle Architecture in Mammalian Neural Stem Cells Influence Mitotic Accuracy during Brain Development
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      DOI: 10.1016/j.cub.2019.07.061

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  120. www.sciencedirect.com www.sciencedirect.com
    Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay
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      DOI: 10.1016/j.molcel.2019.06.001

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  121. www.sciencedirect.com www.sciencedirect.com
    Beneficial effects of sound exposure on auditory cortex development in a mouse model of Fragile X Syndrome
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      DOI: 10.1016/j.nbd.2019.104622

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  122. www.sciencedirect.com www.sciencedirect.com
    In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8–16-mer Oligomer Species
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      RRID:AB_2536530

      DOI: 10.1016/j.celrep.2019.10.089

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  123. www.sciencedirect.com www.sciencedirect.com
    Centromere Dysfunction Compromises Mitotic Spindle Pole Integrity
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      DOI: 10.1016/j.cub.2019.07.052

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  124. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
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      DOI: 10.1186/s12915-018-0616-2

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  125. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo
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      DOI: 10.1016/j.celrep.2019.04.033

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  126. Nov 2018
  127. www.sciencedirect.com www.sciencedirect.com
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  128. www.sciencedirect.com www.sciencedirect.com
    POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication
    1
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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Basal mitophagy is widespread in Drosophila but minimally affected by loss of Pink1 or parkin
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  130. www.sciencedirect.com www.sciencedirect.com
    Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis
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  131. www.sciencedirect.com www.sciencedirect.com
    A C9orf72 ALS/FTD Ortholog Acts in Endolysosomal Degradation and Lysosomal Homeostasis
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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe
    2
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    ncbi.nlm.nih.gov/pmc/articles/PMC5786504/
  133. www.sciencedirect.com www.sciencedirect.com
    A Distinct Class of Genome Rearrangements Driven by Heterologous Recombination
    1
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    sciencedirect.com/science/article/pii/S1097276517309668
  134. www.sciencedirect.com www.sciencedirect.com
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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC5783719/
  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5668231/
  137. Nov 2017
  138. www.sciencedirect.com www.sciencedirect.com
    Transcription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage Responses
    1
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0092867417308796
  139. www.sciencedirect.com www.sciencedirect.com
    Eye Absence Does Not Regulate Planarian Stem Cells during Eye Regeneration
    1
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      Curator: @Zeljana_Babic

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    sciencedirect.com/science/article/pii/S1534580717300710
  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adenosine Kinase Deficiency in the Brain Results in Maladaptive Synaptic Plasticity
    1
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