48 Matching Annotations
  1. Jun 2024
  2. www.sciencedirect.com www.sciencedirect.com
    A cis-regulatory module underlies retinal ganglion cell genesis and axonogenesis
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    1. scibot 04 Jun 2024
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      DOI: 10.1016/j.celrep.2024.114291

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    sciencedirect.com/science/article/pii/S2211124724006193
  3. Jan 2024
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    XIST directly regulates X-linked and autosomal genes in naive human pluripotent cells
    1
    1. scibot 05 Jan 2024
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      DOI: 10.1016/j.cell.2023.11.033

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    sciencedirect.com/science/article/pii/S0092867423013193
  5. Dec 2023
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    AA2P-mediated DNA demethylation synergizes with stem cell agonists to promote expansion of hematopoietic stem cells
    3
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      DOI: 10.1016/j.crmeth.2023.100663

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    2. scibot 17 Dec 2023
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    3. scibot 17 Dec 2023
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      DOI: 10.1016/j.crmeth.2023.100663

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    sciencedirect.com/science/article/pii/S2667237523003405
  7. Nov 2023
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    RNA polymerase II dynamics and mRNA stability feedback scale mRNA amounts with cell size
    1
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      DOI: 10.1016/j.cell.2023.10.012

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    sciencedirect.com/science/article/pii/S0092867423011285
  9. www.biorxiv.org www.biorxiv.org
    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
    1
    1. scibot 03 Nov 2023
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      DOI: 10.1101/2023.10.24.563645

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    biorxiv.org/content/10.1101/2023.10.24.563645v1
  10. Sep 2023
  11. link.springer.com link.springer.com
    SMYD2 regulates vascular smooth muscle cell phenotypic switching and intimal hyperplasia via interaction with myocardin
    1
    1. scibot 07 Sep 2023
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      DOI: 10.1007/s00018-023-04883-9

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    link.springer.com/article/10.1007/s00018-023-04883-9
  12. May 2023
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    Mechanical pressure-induced dedifferentiation of myofibroblasts inhibits scarring via SMYD3/ITGBL1 signaling
    1
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      DOI: 10.1016/j.devcel.2023.04.014

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    sciencedirect.com/science/article/pii/S1534580723001909
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMYD2 Regulates Vascular Smooth Muscle Cell Phenotypic Switching and Intimal Hyperplasia via Interaction with Myocardin
    1
    1. scibot 04 May 2023
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      DOI: 10.21203/rs.3.rs-2721176/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10120764/
  15. Apr 2023
  16. www.sciencedirect.com www.sciencedirect.com
    NSD1 deposits histone H3 lysine 36 dimethylation to pattern non-CG DNA methylation in neurons
    1
    1. scibot 26 Apr 2023
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      DOI: 10.1016/j.molcel.2023.04.001

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    sciencedirect.com/science/article/pii/S1097276523002459
  17. 52.53.155.43 52.53.155.43
    NSD1 deposits histone H3 lysine 36 dimethylation to pattern non-CG DNA methylation in neurons
    1
    1. scibot 11 Apr 2023
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      DOI: 10.1101/2023.02.17.528965

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    52.53.155.43/72c21091426cf476389c237a780c517f6de065b6/2023.02.17.528965v1.full-html.html
  18. Nov 2022
  19. 52.53.155.43 52.53.155.43
    Loss of the Ash2l subunit of histone H3K4 methyltransferase complexes promotes chromatin compaction at promoters
    1
    1. scibot 03 Nov 2022
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      DOI: 10.21203/rs.3.rs-1992778/v1

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  20. Jul 2022
  21. academic.oup.com academic.oup.com
    Induction of senescence upon loss of the Ash2l core subunit of H3K4 methyltransferase complexes
    1
    1. scibot 13 Jul 2022
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      DOI: 10.1093/nar/gkac591

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac591/6640223
  22. Jun 2022
  23. www.sciencedirect.com www.sciencedirect.com
    Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells
    1
    1. scibot 22 Jun 2022
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      DOI: 10.1016/j.chembiol.2022.05.006

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    sciencedirect.com/science/article/pii/S2451945622001982
  24. May 2022
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Binary outcomes of enhancer activity underlie stable random monoallelic expression
    1
    1. scibot 28 May 2022
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      DOI: 10.7554/eLife.74204

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    ncbi.nlm.nih.gov/pmc/articles/PMC9135403/
  26. Apr 2022
  27. aacrjournals.org aacrjournals.org
    Hotspot ESR1 mutations are multimodal and contextual modulators of breast cancer metastasis
    1
    1. scibot 05 Apr 2022
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      DOI: 10.1158/0008-5472.CAN-21-2576

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    aacrjournals.org/cancerres/article/82/7/1321/694048/Hotspot-ESR1-Mutations-Are-Multimodal-and
  28. Dec 2021
  29. www.sciencedirect.com www.sciencedirect.com
    TRACE generates fluorescent human reporter cell lines to characterize epigenetic pathways
    1
    1. scibot 28 Dec 2021
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      DOI: 10.1016/j.molcel.2021.11.035

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    sciencedirect.com/science/article/pii/S1097276521010376
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sumoylation of the human histone H4 tail inhibits p300-mediated transcription by RNA polymerase II in cellular extracts
    1
    1. scibot 01 Dec 2021
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      DOI: 10.7554/eLife.67952

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    ncbi.nlm.nih.gov/pmc/articles/PMC8626089/
  31. Oct 2021
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenomic and Transcriptomic Dynamics During Human Heart Organogenesis
    1
    1. scibot 13 Oct 2021
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      DOI: 10.1161/CIRCRESAHA.120.316704

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    ncbi.nlm.nih.gov/pmc/articles/PMC7554226/
  33. Sep 2021
  34. www.sciencedirect.com www.sciencedirect.com
    Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia
    1
    1. scibot 22 Sep 2021
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      DOI: 10.1016/j.celrep.2021.109725

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    sciencedirect.com/science/article/pii/S2211124721011748
  35. www.sciencedirect.com www.sciencedirect.com
    Reshaping of the androgen-driven chromatin landscape in normal prostate cells by early cancer drivers and effect on therapeutic sensitivity
    1
    1. scibot 08 Sep 2021
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      DOI: 10.1016/j.celrep.2021.109625

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    sciencedirect.com/science/article/pii/S2211124721010639
  36. Aug 2021
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 13 Aug 2021
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      DOI: 10.1016/j.neuron.2017.04.022

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    ncbi.nlm.nih.gov/pmc/articles/PMC5508517/
  38. Jul 2021
  39. www.sciencedirect.com www.sciencedirect.com
    Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer
    1
    1. scibot 30 Jul 2021
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      DOI: 10.1016/j.cell.2018.09.051

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    sciencedirect.com/science/article/pii/S0092867418312637
  40. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transcriptional profiling of human neural precursors post alcohol exposure reveals impaired neurogenesis via dysregulation of ERK signaling and miR‐145
    1
    1. scibot 28 Jul 2021
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      DOI: 10.1111/jnc.14155

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14155
  41. www.sciencedirect.com www.sciencedirect.com
    LSD1 Inhibition Promotes Epithelial Differentiation through Derepression of Fate-Determining Transcription Factors
    1
    1. scibot 27 Jul 2021
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      DOI: 10.1016/j.celrep.2019.07.058

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    sciencedirect.com/science/article/pii/S2211124719309623
  42. www.sciencedirect.com www.sciencedirect.com
    Asymmetric nuclear division in neural stem cells generates sibling nuclei that differ in size, envelope composition, and chromatin organization
    1
    1. scibot 23 Jul 2021
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      DOI: 10.1016/j.cub.2021.06.063

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    sciencedirect.com/science/article/pii/S0960982221008927
  43. Jun 2021
  44. www.sciencedirect.com www.sciencedirect.com
    Protocol for using heterologous spike-ins to normalize for technical variation in chromatin immunoprecipitation
    1
    1. scibot 17 Jun 2021
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      DOI: 10.1016/j.xpro.2021.100609

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    sciencedirect.com/science/article/pii/S2666166721003166
  45. May 2021
  46. www.sciencedirect.com www.sciencedirect.com
    UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex
    1
    1. scibot 09 May 2021
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      DOI: 10.1016/j.stem.2020.12.002

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    sciencedirect.com/science/article/pii/S1934590920305865
  47. www.sciencedirect.com www.sciencedirect.com
    Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in vivo cell engraftment
    1
    1. scibot 05 May 2021
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      DOI: 10.1016/j.celrep.2021.109088

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    sciencedirect.com/science/article/pii/S2211124721004216
  48. Mar 2021
  49. elifesciences.org elifesciences.org
    HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration
    1
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      DOI: 10.7554/eLife.61531

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    elifesciences.org/articles/61531
  50. Feb 2021
  51. www.sciencedirect.com www.sciencedirect.com
    The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers
    1
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      DOI: 10.1016/j.celrep.2021.108742

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    sciencedirect.com/science/article/pii/S2211124721000553
  52. Jan 2020
  53. www.sciencedirect.com www.sciencedirect.com
    Nucleome Dynamics during Retinal Development
    1
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      DOI: 10.1016/j.neuron.2019.08.002

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    sciencedirect.com/science/article/pii/S0896627319306865
  54. www.sciencedirect.com www.sciencedirect.com
    Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS
    1
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      DOI: 10.1016/j.molcel.2019.10.013

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    sciencedirect.com/science/article/pii/S1097276519307919
  55. www.sciencedirect.com www.sciencedirect.com
    Histone Recycling by FACT and Spt6 during Transcription Prevents the Scrambling of Histone Modifications
    1
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      DOI: 10.1016/j.celrep.2019.06.097

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    sciencedirect.com/science/article/pii/S2211124719308836
  56. academic.oup.com academic.oup.com
    Developmental programming: Contribution of Epigenetic Enzymes to Antral Follicular Defects in the Sheep Model of PCOS
    1
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      DOI: 10.1210/en.2019-00389

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    academic.oup.com/endo/article/160/10/2471/5539982
  57. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      DOI: 10.1016/j.ccell.2019.03.001

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    sciencedirect.com/science/article/pii/S1535610819301102
  58. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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      DOI: 10.1111/jnc.14655

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14655
  59. Nov 2018
  60. www.sciencedirect.com www.sciencedirect.com
    Examining the Roles of H3K4 Methylation States with Systematically Characterized Antibodies
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    sciencedirect.com/science/article/pii/S1097276518306750
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    Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate
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    Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses
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    Crystal Structure of the COMPASS H3K4 Methyltransferase Catalytic Module
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    Marked Diversity of Unique Cortical Enhancers Enables Neuron-Specific Tools by Enhancer-Driven Gene Expression
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  66. Nov 2017
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    Loss of TET1 facilitates DLD1 colon cancer cell migration via H3K27me3‐mediated down‐regulation of E‐cadherin
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    The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis
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    PHB Associates with the HIRA Complex to Control an Epigenetic-Metabolic Circuit in Human ESCs
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    A Multi-step Transcriptional and Chromatin State Cascade Underlies Motor Neuron Programming from Embryonic Stem Cells
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