91 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Nuclear RNA homeostasis promotes systems-level coordination of cell fate and senescence
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    sciencedirect.com/science/article/pii/S1934590924000961
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    An RNA-dependent and phase-separated active subnuclear compartment safeguards repressive chromatin domains
    1
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    sciencedirect.com/science/article/pii/S1097276524002259
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intervention with metabolites emulating endogenous cell transitions accelerates muscle regeneration in young and aged mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983034/
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    Modular dual-color BiAD sensors for locus-specific readout of epigenome modifications in single cells
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    sciencedirect.com/science/article/pii/S266723752400064X
  6. Mar 2024
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    Epigenomic tomography for probing spatially defined chromatin state in the brain
    1
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    sciencedirect.com/science/article/pii/S2667237524000638
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    ApoE maintains neuronal integrity via miRNA and H3K27me3-mediated repression.
    2
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    2. scibot 06 Mar 2024
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    sciencedirect.com/science/article/pii/S2589004224004528
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    Synthetic reversed sequences reveal default genomic states
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      DOI: 10.1038/s41586-024-07128-2

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    nature.com/articles/s41586-024-07128-2
  10. www.sciencedirect.com www.sciencedirect.com
    SWI/SNF-dependent genes are defined by their chromatin landscape
    1
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    sciencedirect.com/science/article/pii/S2211124724001839
  11. Feb 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PCID2 dysregulates transcription and viral RNA processing to promote HIV-1 latency
    1
    1. scibot 28 Feb 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10879814/
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    Denaturing purifications demonstrate that PRC2 and other widely reported chromatin proteins do not appear to bind directly to RNA in vivo
    1
    1. scibot 22 Feb 2024
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  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EZH2 Inhibition Promotes Tumor Immunogenicity in Lung Squamous Cell Carcinomas
    1
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  15. link.springer.com link.springer.com
    Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer
    1
    1. scibot 07 Feb 2024
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      DOI: 10.1186/s12935-024-03231-6

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  16. Jan 2024
  17. www.sciencedirect.com www.sciencedirect.com
    XIST directly regulates X-linked and autosomal genes in naive human pluripotent cells
    1
    1. scibot 05 Jan 2024
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      DOI: 10.1016/j.cell.2023.11.033

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    sciencedirect.com/science/article/pii/S0092867423013193
  18. Dec 2023
  19. www.biorxiv.org www.biorxiv.org
    Stem cell quiescence requires PRC2/PRC1-mediated mitochondrial checkpoint
    1
    1. scibot 16 Dec 2023
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      DOI: 10.1101/2021.04.21.440825

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    biorxiv.org/content/10.1101/2021.04.21.440825v1
  20. Oct 2023
  21. www.embopress.org www.embopress.org
    Epigenetic regulation limits competence of pluripotent stem cell-derived oocytes
    1
    1. scibot 20 Oct 2023
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      DOI: 10.15252/embj.2023113955

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    embopress.org/doi/10.15252/embj.2023113955
  22. Sep 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Perturbations in 3D genome organization can promote acquired drug resistance
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113124

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    sciencedirect.com/science/article/pii/S2211124723011361
  24. Aug 2023
  25. www.embopress.org www.embopress.org
    Lineage commitment of dermal fibroblast progenitors is controlled by Kdm6b-mediated chromatin demethylation
    1
    1. scibot 23 Aug 2023
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      DOI: 10.15252/embj.2023113880

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    embopress.org/doi/10.15252/embj.2023113880
  26. 52.53.155.43 52.53.155.43
    Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function
    2
    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112914

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    2. scibot 10 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112914

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  27. Jun 2023
  28. www.sciencedirect.com www.sciencedirect.com
    DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs
    1
    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.cell.2023.05.028

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    sciencedirect.com/science/article/pii/S0092867423005809
  29. May 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Lactobacillus plantarum-derived indole-3-lactic acid ameliorates colorectal tumorigenesis via epigenetic regulation of CD8+ T cell immunity
    1
    1. scibot 17 May 2023
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      DOI: 10.1016/j.cmet.2023.04.015

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    sciencedirect.com/science/article/pii/S1550413123001419
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bidirectional regulation of postmitotic H3K27me3 distributions underlie cerebellar granule neuron maturation dynamics
    1
    1. scibot 16 May 2023
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      DOI: 10.7554/eLife.86273

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    ncbi.nlm.nih.gov/pmc/articles/PMC10181825/
  32. Apr 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Integrative dissection of gene regulatory elements at base resolution
    1
    1. scibot 29 Apr 2023
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      DOI: 10.1016/j.xgen.2023.100318

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    sciencedirect.com/science/article/pii/S2666979X23000861
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    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
    1
    1. scibot 29 Apr 2023
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      DOI: 10.1016/j.molcel.2023.04.005

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    sciencedirect.com/science/article/pii/S1097276523002496
  35. www.sciencedirect.com www.sciencedirect.com
    Evolutionarily distinct and sperm-specific supersized chromatin loops are marked by Helitron transposons in Xenopus tropicalis
    1
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      DOI: 10.1016/j.celrep.2023.112151

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    sciencedirect.com/science/article/pii/S2211124723001626
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lineage Commitment of Dermal Fibroblast Progenitors is Mediated by Chromatin De-Repression
    1
    1. scibot 12 Apr 2023
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      DOI: 10.1101/2023.03.07.531478

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    ncbi.nlm.nih.gov/pmc/articles/PMC10028926/
  37. Feb 2023
  38. www.sciencedirect.com www.sciencedirect.com
    Bat pluripotent stem cells reveal unusual entanglement between host and viruses
    1
    1. scibot 23 Feb 2023
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      DOI: 10.1016/j.cell.2023.01.011

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    sciencedirect.com/science/article/pii/S0092867423000417
  39. Jan 2023
  40. www.cell.com www.cell.com
    Glucose dissociates DDX21 dimers to regulate mRNA splicing and tissue differentiation
    1
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      DOI: 10.1016/j.cell.2022.12.004

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    cell.com/cell/fulltext/S0092-8674(22)01517-3
  41. Dec 2022
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antifungal mechanisms of silver nanoparticles on mycotoxin producing rice false smut fungus
    1
    1. scibot 30 Dec 2022
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      DOI: 10.1016/j.isci.2022.105763

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    ncbi.nlm.nih.gov/pmc/articles/PMC9793317/
  43. aacrjournals.org aacrjournals.org
    BAF complex maintains glioma stem cells in pediatric H3K27M-glioma
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      DOI: 10.1158/2159-8290.CD-21-1491

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    aacrjournals.org/cancerdiscovery/article/12/12/2880/711164/BAF-Complex-Maintains-Glioma-Stem-Cells-in
  44. Oct 2022
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prdm14 promotes mouse ESC self-renewal and PGCLC specification through enhancement of Stat3 activity
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      DOI: 10.1016/j.isci.2022.105293

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    ncbi.nlm.nih.gov/pmc/articles/PMC9589213/
  46. May 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Nde1 is required for heterochromatin compaction and stability in neocortical neurons
    1
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      DOI: 10.1016/j.isci.2022.104354

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    sciencedirect.com/science/article/pii/S2589004222006253
  48. Apr 2022
  49. www.sciencedirect.com www.sciencedirect.com
    L3MBTL2-mediated CGA transcriptional suppression promotes pancreatic cancer progression through modulating autophagy
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      DOI: 10.1016/j.isci.2022.104249

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  50. Mar 2022
  51. www.sciencedirect.com www.sciencedirect.com
    The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes
    1
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      DOI: 10.1016/j.celrep.2022.110524

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    sciencedirect.com/science/article/pii/S2211124722002601
  52. www.sciencedirect.com www.sciencedirect.com
    dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region
    1
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      DOI: 10.1016/j.celrep.2022.110457

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    sciencedirect.com/science/article/pii/S221112472200184X
  53. www.sciencedirect.com www.sciencedirect.com
    An Inducible CRISPR/Cas9 Screen Identifies DTX2 as a Transcriptional Regulator of Human Telomerase
    1
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      DOI: 10.1016/j.isci.2022.103813

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    sciencedirect.com/science/article/pii/S2589004222000839
  54. Feb 2022
  55. www.sciencedirect.com www.sciencedirect.com
    Interferons reshape the 3D conformation and accessibility of macrophage chromatin
    1
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      DOI: 10.1016/j.isci.2022.103840

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    sciencedirect.com/science/article/pii/S2589004222001109
  56. Jan 2022
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Establishment of developmental gene silencing by ordered polycomb complex recruitment in early zebrafish embryos
    1
    1. scibot 26 Jan 2022
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      DOI: 10.7554/eLife.67738

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    ncbi.nlm.nih.gov/pmc/articles/PMC8769650/
  58. Dec 2021
  59. elifesciences.org elifesciences.org
    5-Hydroxymethylcytosine-mediated active demethylation is required for mammalian neuronal differentiation and function
    2
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      DOI: 10.7554/eLife.66973

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    2. scibot 22 Dec 2021
      RRID:AB_2561020Active

      DOI: 10.7554/eLife.66973

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    Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State
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    The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain
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    Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses
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    Genetic Intersection of Tsix and Hedgehog Signaling during the Initiation of X-Chromosome Inactivation
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    An endosiRNA-Based Repression Mechanism Counteracts Transposon Activation during Global DNA Demethylation in Embryonic Stem Cells
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    Multiscale 3D Genome Rewiring during Mouse Neural Development
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  113. europepmc.org europepmc.org
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  114. Nov 2017
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    The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis
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    Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation
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    Metazoan Nuclear Pores Provide a Scaffold for Poised Genes and Mediate Induced Enhancer-Promoter Contacts
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    Destabilization of B2 RNA by EZH2 Activates the Stress Response
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    CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression
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    Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons
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    Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons
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    A Multi-step Transcriptional and Chromatin State Cascade Underlies Motor Neuron Programming from Embryonic Stem Cells
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