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Safe immunosuppression-resistant pan-cancer immunotherapeutics by velcro-like density-dependent targeting of tumor-associated carbohydrate antigens

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1. scibot 27 Sep 2025
  
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  DOI: 10.1016/j.cell.2025.09.001
  
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sciencedirect.com/science/article/pii/S0092867425010323
Aug 2025
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1-s2.0-S2589004225010338-main-html.html

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1. scibot 12 Aug 2025
  
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  DOI: 10.1016/j.isci.2025.112772
  
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52.53.155.43/8b0897d2d35a8ab9ab351db77e0eeb32b8358112/1-s2.0-S2589004225010338-main-html.html
Jul 2025
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Gasdermin-D-mediated epithelial-immune circuit synchronizes nutrient absorption and host defense in the small intestine

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1. scibot 25 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.019
  
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sciencedirect.com/science/article/pii/S1074761325003097
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CINTER-seq: Chemical profiling reveals interaction-dependent cell landscapes and gene signatures in vivo

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1. scibot 17 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.011
  
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sciencedirect.com/science/article/pii/S1074761325002808
Jun 2025
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A hypomorphic Il2rb mutant mouse model recapitulates and reveals mechanisms of human T cell immune dysregulation in IL-2Rβ deficiency

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115902
  
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sciencedirect.com/science/article/pii/S2211124725006734
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MET pathway inhibition increases chemo-immunotherapy efficacy in small cell lung cancer

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.xcrm.2025.102194
  
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sciencedirect.com/science/article/pii/S2666379125002678
May 2025
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Maternal natural killer cells drive neuroimmune disorders in offspring through aberrant secretion of extracellular granzyme B

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1. scibot 18 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.028
  
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Overcoming NK-mediated rejection by anti-3rd-party central memory veto CD8 T cells through downregulation of DNAM-1 on alloreactive NK cells

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115674
  
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sciencedirect.com/science/article/pii/S2211124725004450
Apr 2025
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KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway

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1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115595
  
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Rorγt-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens

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1. scibot 05 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.03.020
  
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sciencedirect.com/science/article/pii/S0092867425002934
Mar 2025
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Translation dysregulation in cancer as a source for targetable antigens

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1. scibot 28 Mar 2025
  
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  DOI: 10.1016/j.ccell.2025.03.003
  
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sciencedirect.com/science/article/pii/S1535610825000820
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The Nuclear Receptor NR1B1/RARα Arrests the Differentiation of Anti-Tumor Effector Cytotoxic T Cells

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1. scibot 13 Mar 2025
  
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  DOI: 10.1002/advs.202410241
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202410241
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The polyamine-regulating enzyme SSAT1 impairs tissue regulatory T cell function in chronic cutaneous inflammation

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1. scibot 04 Mar 2025
  
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  RRID:AB_2561456
  
  DOI: 10.1016/j.immuni.2025.02.011
  
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sciencedirect.com/science/article/pii/S1074761325000780
Feb 2025
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CV1-secreting sCAR-T cells potentiate the abscopal effect of microwave ablation in heterogeneous tumors

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1. scibot 20 Feb 2025
  
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  RRID:AB_2561456
  
  DOI: 10.1016/j.xcrm.2025.101965
  
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BPS Publications

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1. scibot 07 Feb 2025
  
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  RRID:AB_2561456
  
  DOI: 10.1111/bph.17344
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17344
Jan 2025
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Phenotypic plasticity and increased infiltration of peripheral blood-derived TREM1+ mono-macrophages following radiotherapy in rectal cancer

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1. scibot 14 Jan 2025
  
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  DOI: 10.1016/j.xcrm.2024.101887
  
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Mechanical Force-Induced cGAS Activation in Carcinoma Cells Facilitates Splenocytes into Liver to Drive Metastasis

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1. scibot 11 Jan 2025
  
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  DOI: 10.1002/advs.202401127
  
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onlinelibrary.wiley.com/doi/10.1002/advs.202401127
Dec 2024
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Nucleo-cytosolic acetyl-CoA drives tumor immune evasion by regulating PD-L1 in melanoma

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1. scibot 02 Dec 2024
  
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  RRID:AB_2561456
  
  DOI: 10.1016/j.celrep.2024.115015
  
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sciencedirect.com/science/article/pii/S2211124724013664
Oct 2024
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A High-Content Screen Identifies Drugs That Restrict Tumor Cell Extravasation across the Endothelial Barrier

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1. scibot 02 Oct 2024
  
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  DOI: 10.1158/0008-5472.CAN-19-3911
  
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aacrjournals.org/cancerres/article/81/3/619/648134/A-High-Content-Screen-Identifies-Drugs-That
Apr 2024
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Blocking cGAS-STING pathway promotes post-stroke functional recovery in an extended treatment window via facilitating remyelination

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1. scibot 25 Apr 2024
  
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  DOI: 10.1016/j.medj.2024.03.018
  
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sciencedirect.com/science/article/pii/S2666634024001302
Mar 2024
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Adipose stem cells control obesity-induced T cell infiltration into adipose tissue

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1. scibot 19 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113963
  
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Low-dose Decitabine enhances the efficacy of viral cancer vaccines for immunotherapy.

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1. scibot 12 Mar 2024
  
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  DOI: 10.1016/j.omton.2024.200766
  
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52.53.155.43/8c6eb3b4d009a4f511a3160975bf106d9641ff9c/1-s2.0-S2950329924000080-main-html.html
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Maternal inflammation regulates fetal emergency myelopoiesis

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1. scibot 01 Mar 2024
  
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  DOI: 10.1016/j.cell.2024.02.002
  
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  DOI: 10.1016/j.cell.2024.02.002
  
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Feb 2024
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Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies

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1. scibot 22 Feb 2024
  
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  DOI: 10.1038/s41467-024-45854-3
  
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nature.com/articles/s41467-024-45854-3
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Revealing splenectomy-driven microRNA hsa-7b-5p’s role in pancreatic cancer progression

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1. scibot 16 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.109045
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10864800/
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Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche

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  DOI: 10.1038/s41467-024-45471-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10844594/
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Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells

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1. scibot 06 Feb 2024
  
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  DOI: 10.1016/j.cmet.2024.01.005
  
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Jan 2024
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Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors

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1. scibot 19 Jan 2024
  
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  DOI: 10.1016/j.xcrm.2023.101374
  
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Dec 2023
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Apoptosis releases hydrogen sulfide to inhibit Th17 cell differentiation

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1. scibot 19 Dec 2023
  
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  DOI: 10.1016/j.cmet.2023.11.012
  
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sciencedirect.com/science/article/pii/S1550413123004448
Oct 2023
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Lipid accumulation-mediated histone hypoacetylation drives persistent NK cell dysfunction in anti-tumor immunity

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113211
  
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sciencedirect.com/science/article/pii/S2211124723012238
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Enhancing CAR T-cell Therapy Using Fab-Based Constitutively Heterodimeric Cytokine Receptors

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1. scibot 07 Sep 2023
  
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  DOI: 10.1158/2326-6066.CIR-22-0640
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10472109/
Aug 2023
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A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells

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1. scibot 16 Aug 2023
  
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  DOI: 10.1016/j.xcrm.2023.101154
  
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Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection

1
1. scibot 12 Aug 2023
  
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  DOI: 10.1016/j.immuni.2023.07.014
  
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sciencedirect.com/science/article/pii/S1074761323003278
Jul 2023
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A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity

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1. scibot 13 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112813
  
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sciencedirect.com/science/article/pii/S2211124723008240
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Enhanced bypass of PD-L1 translation reduces the therapeutic response to mTOR kinase inhibitors

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1. scibot 08 Jul 2023
  
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Rebalancing liver-infiltrating CCR3+ and CD206+ monocytes improves diet-induced NAFLD

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Vectored immunoprophylaxis and treatment of SARS-CoV-2 infection in a preclinical model

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Mar 2023
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Hematopoietic stem cells preferentially traffic misfolded proteins to aggresomes and depend on aggrephagy to maintain protein homeostasis

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Feb 2023
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TNFR2+ regulatory T cells protect against bacteremic pneumococcal pneumonia by suppressing IL-17A-producing γδ T cells in the lung

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The loss of epithelial Smad4 drives immune evasion via CXCL1 while displaying vulnerability to combinatorial immunotherapy in gastric cancer

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Protocol to assess the antitumor efficacy of an immunotherapeutic peptide in syngeneic orthotopic glioma mouse models

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Lymphatic vessels in bone support regeneration after injury

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Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes

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MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors

1
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METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism

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Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop

1
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Oct 2022
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Cbl-b Restrains Priming of Pathogenic Th17 Cells via the Inhibition of IL-6 Production by Macrophages

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Sep 2022
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IRE1α overexpression in malignant cells limits tumor progression by inducing an anti-cancer immune response

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Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment

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Nanocarriers based on bacterial membrane materials for cancer vaccine delivery

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Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells

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Amino acid catabolism regulates hematopoietic stem cell proteostasis via a GCN2-eIF2α axis

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Viral infection engenders bona fide and bystander subsets of lung-resident memory B cells through a permissive mechanism

1
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Unravelling the sex-specific diversity and functions of adrenal gland macrophages

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Poroptosis: a form of cell death depending on plasma membrane nanopores formation

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Maladaptive innate immune training of myelopoiesis links inflammatory comorbidities

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ILC precursors differentiate into metabolically distinct ILC1-like cells during Mycobacterium tuberculosis infection

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Type 1 innate lymphoid cells regulate the onset of Toxoplasma gondii-induced neuroinflammation

1
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Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells

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Notch-mediated lactate metabolism regulates MDSC development through the Hes1/MCT2/c-Jun axis

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Interferon gamma constrains type 2 lymphocyte niche boundaries during mixed inflammation

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Macrophages transfer mitochondria to sensory neurons to resolve inflammatory pain

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Myeloid cell subsets that express latency-associated peptide promote cancer growth by modulating T cells

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Indoleamine 2,3-dioxygenase 1 is essential for sustaining durable antibody responses

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A non-classical monocyte-derived macrophage subset provides a splenic replication niche for intracellular Salmonella

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MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function

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Arthritis flares mediated by tissue-resident memory T cells in the joint

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BPS Publications

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  DOI: 10.1111/bph.15652
  
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Sep 2021
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Cognate recognition of microbial antigens defines constricted CD4+ T cell receptor repertoires in the inflamed colon

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A TLR7 antagonist restricts interferon-dependent and -independent immunopathology in a mouse model of severe influenza

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  DOI: 10.1084/jem.20201631
  
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Methods for Studying Mouse and Human Invariant Natural Killer T Cells

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  DOI: 10.1007/978-1-0716-1775-5_4
  
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B19-VLPs as an effective delivery system for tumour antigens to induce humoral and cellular immune responses against triple negative breast cancer

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  DOI: 10.1016/j.imlet.2021.09.002
  
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Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes

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  DOI: 10.1016/j.celrep.2021.109608
  
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Hsf1 promotes hematopoietic stem cell fitness and proteostasis in response to ex vivo culture stress and aging

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  DOI: 10.1016/j.stem.2021.07.009
  
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Untitled document

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  DOI: 10.1016/j.immuni.2018.10.008
  
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May 2021
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Invariant natural killer T cells coordinate removal of senescent cells

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  DOI: 10.1016/j.medj.2021.04.014
  
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A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation

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1. scibot 22 Apr 2021
  
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  DOI: 10.1016/j.ccell.2021.02.003
  
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Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis

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  DOI: 10.1016/j.cell.2021.01.049
  
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sciencedirect.com/science/article/pii/S0092867421000921
Mar 2021
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Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy

1
1. scibot 09 Mar 2021
  
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  DOI: 10.1016/j.cell.2020.10.045
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7927154/
Feb 2021
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IL-17A Activated by Toll-Like Receptor 9 Contributes to Development of Septic Acute Kidney Injury

1
1. scibot 24 Feb 2021
  
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  DOI: 10.1152/ajprenal.00313.2019
  
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physiology.org/doi/abs/10.1152/ajprenal.00313.2019
Dec 2020
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BPS Publications

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1. scibot 07 Dec 2020
  
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  RRID:AB_2561456
  
  DOI: 10.1111/bph.15216
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15216
Sep 2020
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Visualization of T Cell Migration in the Spleen Reveals a Network of Perivascular Pathways that Guide Entry into T Zones

1
1. scibot 23 Sep 2020
  
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  RRID:AB_2561456
  
  DOI: 10.1016/j.immuni.2020.03.010
  
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CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b−CD103+ DCs

1
1. scibot 17 Sep 2020
  
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  AB_2561456
  
  DOI: 10.1016/j.celrep.2020.02.103
  
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CD49a Regulates Cutaneous Resident Memory CD8+ T Cell Persistence and Response

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1. scibot 16 Sep 2020
  
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  RRID:AB_2561456
  
  DOI: 10.1016/j.celrep.2020.108085
  
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ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis

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1. scibot 10 Sep 2020
  
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  RRID:AB_2561456
  
  DOI: 10.1016/j.ccell.2020.02.006
  
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Neutrophil elastase triggers the development of autoimmune diabetes by exacerbating innate immune responses in pancreatic islets of non-obese diabetic mice

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1. scibot 06 Sep 2020
  
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  RRID:AB_2561456
  
  DOI: 10.1042/CS20200021
  
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portlandpress.com/clinsci/article/134/13/1679/225508/Neutrophil-elastase-triggers-the-development-of
Jan 2020
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The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis

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  DOI: 10.1016/j.celrep.2019.06.007
  
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An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer

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  DOI: 10.1016/j.ccell.2019.08.008
  
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Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity

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  DOI: 10.1016/j.celrep.2019.09.065
  
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NIX-Mediated Mitophagy Promotes Effector Memory Formation in Antigen-Specific CD8+ T Cells

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2561456
  
  DOI: 10.1016/j.celrep.2019.10.032
  
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Untitled document

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  DOI: 10.1016/j.immuni.2019.01.021
  
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Nov 2018
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Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity

1
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Untitled document

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ncbi.nlm.nih.gov/pmc/articles/PMC5896201/
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Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S193459091830119X
Nov 2017
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Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells

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ncbi.nlm.nih.gov/pmc/articles/PMC5510238/
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Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells

1
1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S0092867416314660

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