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An IL-12 partial agonist sustains intratumoral lymphocyte activation and detoxifies systemic IL-12 therapy

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  DOI: 10.1016/j.celrep.2025.116757
  
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sciencedirect.com:5037/science/article/pii/S2211124725015293
Oct 2025
54.241.53.176 54.241.53.176

2025.10.24.684274v1.full-html.html

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  DOI: 10.1101/2025.10.24.684274
  
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54.241.53.176/560b23241d86210770f41b5bc2071167c8b2fca6/2025.10.24.684274v1.full-html.html
Sep 2025
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IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunity

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  DOI: 10.1016/j.cell.2025.08.017
  
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sciencedirect.com/science/article/pii/S0092867425009729
Aug 2025
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Succinate preserves CD8+ T cell fitness to augment antitumor immunity

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  DOI: 10.1016/j.immuni.2025.07.017
  
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sciencedirect.com/science/article/pii/S1074761325003267
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Bifidobacterium animalis suppresses non-small cell lung cancer progression and modulates tumor immunity through indole-3-acetic acid

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sciencedirect.com/science/article/pii/S2211124725009039
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Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression

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sciencedirect.com/science/article/pii/S1535610825003186
Jun 2025
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The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis

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  DOI: 10.1016/j.cell.2025.05.029
  
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sciencedirect.com/science/article/pii/S0092867425006166
May 2025
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Bacteroides fragilis promotes chemoresistance in colorectal cancer, and its elimination by phage VA7 restores chemosensitivity

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  DOI: 10.1016/j.chom.2025.05.004
  
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sciencedirect.com/science/article/pii/S1931312825001830
Apr 2025
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Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity

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  DOI: 10.1016/j.cell.2025.03.017
  
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sciencedirect.com/science/article/pii/S0092867425002909
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Rorγt-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens

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1. scibot 05 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.03.020
  
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sciencedirect.com/science/article/pii/S0092867425002934
52.53.155.43 52.53.155.43

PD-html.html

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  DOI: 10.1101/2025.03.25.645270
  
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52.53.155.43/639914d725a708fad2e0783fbcce6b5221fc6f0d/PD-html.html
Feb 2025
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Mechanistic insight into the induction of liver tissue-resident memory CD8+ T cells by glycolipid-peptide vaccination

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1. scibot 13 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115295
  
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sciencedirect.com/science/article/pii/S221112472500066X
Dec 2024
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Mannose metabolism reshapes T cell differentiation to enhance anti-tumor immunity

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1. scibot 06 Dec 2024
  
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  DOI: 10.1016/j.ccell.2024.11.003
  
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sciencedirect.com/science/article/pii/S1535610824004380
Mar 2024
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Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness

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1. scibot 15 Mar 2024
  
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  DOI: 10.1016/j.ccell.2024.02.016
  
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  DOI: 10.1016/j.ccell.2024.02.016
  
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  RRID:AB_2562100
  
  DOI: 10.1016/j.ccell.2024.02.016
  
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sciencedirect.com/science/article/pii/S1535610824000606
Sep 2023
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Low dietary fiber intake impairs small intestinal Th17 and intraepithelial T cell development over generations

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113140
  
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sciencedirect.com/science/article/pii/S221112472301152X
Aug 2023
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Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection

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1. scibot 12 Aug 2023
  
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  DOI: 10.1016/j.immuni.2023.07.014
  
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sciencedirect.com/science/article/pii/S1074761323003278
Jun 2023
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Loss of PBAF promotes expansion and effector differentiation of CD8+ T cells during chronic viral infection and cancer

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1. scibot 21 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112649
  
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sciencedirect.com/science/article/pii/S2211124723006605
May 2023
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Targeting stromal cell sialylation reverses T cell-mediated immunosuppression in the tumor microenvironment

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1. scibot 11 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112475
  
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sciencedirect.com/science/article/pii/S2211124723004862
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M cell maturation and cDC activation determine the onset of adaptive immune priming in the neonatal Peyer’s patch

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1. scibot 03 May 2023
  
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  DOI: 10.1016/j.immuni.2023.04.002
  
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sciencedirect.com/science/article/pii/S107476132300170X
Sep 2022
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Profiling of Tregs across tissues reveals plasticity in ST2 expression and hierarchies in tissue-specific phenotypes

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  DOI: 10.1016/j.isci.2022.104998
  
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sciencedirect.com/science/article/pii/S2589004222012706
May 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Functional assessment of the cell-autonomous role of NADase CD38 in regulating CD8+ T cell exhaustion

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1. scibot 21 May 2022
  
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  DOI: 10.1016/j.isci.2022.104347
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9117873/
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Mycobacterium tuberculosis impedes CD40-dependent notch signaling to restrict Th17 polarization during infection

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  DOI: 10.1016/j.isci.2022.104305
  
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sciencedirect.com/science/article/pii/S2589004222005752
Jan 2022
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CRISPitope: A generic platform to model target antigens for adoptive T cell transfer therapy in mouse tumor models

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1. scibot 08 Jan 2022
  
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  DOI: 10.1016/j.xpro.2021.101038
  
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sciencedirect.com/science/article/pii/S2666166721007449
Dec 2021
www-sciencedirect-com.proxy.uchicago.edu www-sciencedirect-com.proxy.uchicago.edu

Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses

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1. scibot 01 Dec 2021
  
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  DOI: 10.1016/j.cell.2021.11.007
  
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www-sciencedirect-com.proxy.uchicago.edu/science/article/pii/S0092867421013222
Oct 2021
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Attenuation of apoptotic cell detection triggers thymic regeneration after damage

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1. scibot 06 Oct 2021
  
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  DOI: 10.1016/j.celrep.2021.109789
  
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sciencedirect.com/science/article/pii/S2211124721012481
Jul 2021
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Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING

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sciencedirect.com/science/article/pii/S2211124721008251
May 2021
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DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T cells

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1. scibot 08 May 2021
  
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  DOI: 10.1016/j.molcel.2021.01.038
  
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sciencedirect.com/science/article/pii/S1097276521000587
Apr 2021
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Adrenergic regulation of the vasculature impairs leukocyte interstitial migration and suppresses immune responses

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  DOI: 10.1016/j.immuni.2021.03.025
  
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sciencedirect.com/science/article/pii/S1074761321001370
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Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade

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  DOI: 10.1016/j.molcel.2021.03.037
  
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sciencedirect.com/science/article/pii/S109727652100232X
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Long-term evolution and short-term adaptation of microbiota strains and sub-strains in mice

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1. scibot 19 Apr 2021
  
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  DOI: 10.1016/j.chom.2021.02.001
  
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sciencedirect.com/science/article/pii/S1931312821000470
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Self-renewal of double-negative 3 early thymocytes enables thymus autonomy but compromises the β-selection checkpoint

1
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  DOI: 10.1016/j.celrep.2021.108967
  
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sciencedirect.com/science/article/pii/S2211124721002813
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Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis

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1. scibot 11 Apr 2021
  
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  DOI: 10.1016/j.cell.2021.01.049
  
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sciencedirect.com/science/article/pii/S0092867421000921
Feb 2021
elifesciences.org elifesciences.org

The gut microbiota is a transmissible determinant of skeletal maturation

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1. scibot 28 Feb 2021
  
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  DOI: 10.7554/eLife.64237
  
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elifesciences.org/articles/64237
Sep 2020
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Cell Competition, the Kinetics of Thymopoiesis, and Thymus Cellularity Are Regulated by Double-Negative 2 to 3 Early Thymocytes

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1. scibot 03 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107910
  
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  RRID:AB_2562100 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720308913
Jan 2020
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Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors

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1. scibot 13 Jan 2020
  
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  RRID:AB_2562100
  
  DOI: 10.1016/j.ccell.2019.05.004
  
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  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2562100
  
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  RRID:AB_2562100 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_2562100

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scibot

URL

sciencedirect.com/science/article/pii/S1535610819302429
Nov 2018
www.sciencedirect.com www.sciencedirect.com

CD8+ T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T Cells that Seed a Large and Flexible Niche in the Liver

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2562100
  
  Curator: @evieth
  
  Resource used:
  
  (BioLegend Cat# 100748, RRID:AB_2562100)
  
  SciCrunch record: RRID:AB_2562100
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2562100 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_2562100

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scibot

URL

sciencedirect.com/science/article/pii/S221112471831413X
www.sciencedirect.com www.sciencedirect.com

Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2562100
  
  Resource used:
  
  (BioLegend Cat# 100748, RRID:AB_2562100)
  
  SciCrunch record: RRID:AB_2562100
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2562100
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RRID:AB_2562100

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scibot

URL

sciencedirect.com/science/article/pii/S1074761317304235