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Krüppel-like factor 2 programs early exhausted T cell states and restrains antiviral immunity

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1. scibot 29 Apr 2026
  
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  DOI: 10.1016/j.immuni.2026.03.029
  
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sciencedirect.com/science/article/pii/S1074761326001408
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MAIT cells egress the thymus at several maturation stages with selective capacity to seed different tissues

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1. scibot 24 Apr 2026
  
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  DOI: 10.1016/j.immuni.2026.03.024
  
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sciencedirect.com/science/article/pii/S1074761326001354
Apr 2026
54.241.53.176 54.241.53.176

1-s2.0-S2589004226009314-main-html.html

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1. scibot 02 Apr 2026
  
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  AB_2562451
  
  DOI: 10.1016/j.isci.2026.115556
  
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54.241.53.176/2c3d384c1047ca69634acbe35bc39827aebb187b/1-s2.0-S2589004226009314-main-html.html
Mar 2026
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Tuft cells promote reactivation of memory Th2 cells and are required for protective immunity to intestinal helminth re-infection

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1. scibot 31 Mar 2026
  
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  DOI: 10.1016/j.immuni.2026.02.022
  
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sciencedirect.com/science/article/pii/S1074761326000920
Feb 2026
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Law-NQO1 redox boosts the pentose phosphate pathway to confer stem-like properties and antitumor durability in effector CD8+ T cells

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1. scibot 26 Feb 2026
  
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  DOI: 10.1016/j.chembiol.2026.02.001
  
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sciencedirect.com/science/article/pii/S2451945626000334
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Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition

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1. scibot 03 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.016
  
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sciencedirect.com/science/article/pii/S1074761326000385
Dec 2025
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Positioning and reversible suppression of CCR7+ dendritic cells in perivascular tumor niches shape cancer immunity

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1. scibot 20 Dec 2025
  
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  DOI: 10.1016/j.immuni.2025.11.020
  
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sciencedirect.com:5037/science/article/pii/S1074761325005229
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Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

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1. scibot 17 Dec 2025
  
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  DOI: 10.1016/j.cell.2025.11.023
  
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sciencedirect.com:5037/science/article/pii/S0092867425013583
Nov 2025
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Developing a therapeutic elastase that stimulates anti-tumor immunity by selectively killing cancer cells

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1. scibot 13 Nov 2025
  
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  DOI: 10.1016/j.xcrm.2025.102446
  
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sciencedirect.com/science/article/pii/S2666379125005191
Oct 2025
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Distinct T cell functions enable efficient immunoediting and prevent tumor emergence of developing sarcomas

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1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.ccell.2025.09.005
  
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sciencedirect.com/science/article/pii/S1535610825003976
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Lrrk2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis

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1. scibot 06 Sep 2025
  
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  DOI: 10.1038/s41531-025-01077-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12397289/
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CD226 identifies effector CD8+ T cells during tuberculosis and costimulates recognition of Mycobacterium tuberculosis-infected macrophages

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116184
  
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sciencedirect.com/science/article/pii/S2211124725009556
Aug 2025
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Polyamines regulate adaptive antitumor immunity by functional specialization of regulatory T cells

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1. scibot 01 Aug 2025
  
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  DOI: 10.1016/j.immuni.2025.07.007
  
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sciencedirect.com/science/article/pii/S1074761325003164
Jul 2025
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The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells

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1. scibot 08 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.001
  
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sciencedirect.com/science/article/pii/S1074761325002481
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Augment proteasome inhibitor efficacy activates CD8+ T cell-mediated antitumor immunity in breast cancer

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1. scibot 02 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102211
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12281435/
Jun 2025
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Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8+ T cells

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.immuni.2025.05.025
  
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sciencedirect.com/science/article/pii/S1074761325002468
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Satb1 directs the differentiation of TH17 cells through suppression of IL-2 expression

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1. scibot 18 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115866
  
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sciencedirect.com/science/article/pii/S2211124725006370
Mar 2025
www.cell.com www.cell.com

Modulation of lipid nanoparticle-formulated plasmid DNA drives innate immune activation promoting adaptive immunity

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1. scibot 24 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.102035
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00108-9
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Unveiling IRF4-steered regulation of context-dependent effector programs in CD4+ T cells under Th17- and Treg-skewing conditions

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1. scibot 11 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115407
  
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sciencedirect.com/science/article/pii/S2211124725001780
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Low-dose irradiation of the gut improves the efficacy of PD-L1 blockade in metastatic cancer patients

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1. scibot 11 Mar 2025
  
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  DOI: 10.1016/j.ccell.2025.02.010
  
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sciencedirect.com/science/article/pii/S1535610825000625
Jan 2025
52.53.155.43 52.53.155.43

Maternal Immunoglobulin A regulates the development of the neonatal microbiota and intestinal microbiota-specific CD4+ T cell responses

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1. scibot 31 Jan 2025
  
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  DOI: 10.1101/2024.06.10.598156
  
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52.53.155.43/5d9f175a1366852853c2411b63ad8211a7d72182/2024.06.10.598156v1.full-html.html
Dec 2024
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Interleukin-2 receptor signaling acts as a checkpoint that influences the distribution of regulatory T cell subsets

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1. scibot 18 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111248
  
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1-s2.0-S2589004224027755-main-html.html

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1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111548
  
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52.53.155.43/db6bd63f509ce2b1671194beaf08c82cb9e01ddc/1-s2.0-S2589004224027755-main-html.html
Nov 2024
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HDAC1 fine-tunes Th17 polarization in vivo to restrain tissue damage in fungal infections

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1. scibot 28 Nov 2024
  
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  DOI: 10.1016/j.celrep.2024.114993
  
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sciencedirect.com/science/article/pii/S2211124724013445
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Combined TLR2/TLR4 activation equip non-mucosal dendritic cells to prime Th1 cells with gut tropism

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1. scibot 16 Nov 2024
  
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  DOI: 10.1016/j.isci.2024.111232
  
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sciencedirect.com/science/article/pii/S258900422402457X
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Macrophage-mediated myelin recycling fuels brain cancer malignancy

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1. scibot 02 Oct 2024
  
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  DOI: 10.1016/j.cell.2024.07.030
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11429458/
Jul 2024
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Metabolic reprogramming and dysregulated IL-17 production impairs CD4 T cell function post sepsis

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1. scibot 19 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110114
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11251092/
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GRP75-dependent mitochondria-ER contacts ensure cell survival during early mouse thymocyte development

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1. scibot 11 Jul 2024
  
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  DOI: 10.1016/j.devcel.2024.06.007
  
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cell.com/developmental-cell/abstract/S1534-5807(24)00385-X
Apr 2024
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Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration

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1. scibot 19 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114114
  
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sciencedirect.com/science/article/pii/S221112472400442X
Dec 2023
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Immunotherapy targeting B cells and long-lived plasma cells effectively eliminates pre-existing donor-specific allo-antibodies

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1. scibot 20 Dec 2023
  
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  DOI: 10.1016/j.xcrm.2023.101336
  
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sciencedirect.com/science/article/pii/S2666379123005530
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NK cells propagate T cell immunity following in situ tumor vaccination

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1. scibot 17 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113556
  
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sciencedirect.com/science/article/pii/S2211124723015681
Jul 2023
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Protocol to expand and CRISPR-Cas9 genomic edit murine MAIT cells for subsequent in vivo studies

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1. scibot 13 Jul 2023
  
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  DOI: 10.1016/j.xpro.2023.102419
  
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sciencedirect.com/science/article/pii/S2666166723003866
Jun 2023
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation

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1. scibot 07 Jun 2023
  
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  DOI: 10.1016/j.immuni.2023.05.010
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10501989/
Mar 2023
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A monoclonal Trd chain supports the development of the complete set of functional γδ T cell lineages

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1. scibot 16 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112253
  
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sciencedirect.com/science/article/pii/S2211124723002644
Feb 2023
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Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer

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1. scibot 24 Feb 2023
  
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  DOI: 10.1016/j.ccell.2023.01.004
  
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Interplay between liver and blood stages of Plasmodium infection dictates malaria severity via γδ T cells and IL-17-promoted stress erythropoiesis

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Role of MR1-driven signals and amphiregulin on the recruitment and repair function of MAIT cells during skin wound healing

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NKG2D signaling shifts the balance of CD8 T cells from single cytokine- to polycytokine-producing effector cells

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IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer

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CD8 memory precursor cell generation is a continuous process

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Lenalidomide bypasses CD28 co-stimulation to reinstate PD-1 immunotherapy by activating Notch signaling

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Mucus sialylation determines intestinal host-commensal homeostasis

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  RRID:AB_2562451
  
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The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer

1
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JAK1 signaling in dendritic cells promotes peripheral tolerance in autoimmunity through PD-L1-mediated regulatory T cell induction

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  DOI: 10.1016/j.celrep.2022.110420
  
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Neutrophil extracellular traps and their histones promote Th17 cell differentiation directly via TLR2

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  DOI: 10.1038/s41467-022-28172-4
  
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Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy

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Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses

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Arthritis flares mediated by tissue-resident memory T cells in the joint

1
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  DOI: 10.1016/j.celrep.2021.109902
  
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In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target

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IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer’s disease

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Aug 2021
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The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

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Untitled document

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May 2021
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Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist

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  Anti-mouse CD44 (IM7) rat monoclonal
  
  DOI: 10.7554/eLife.65777
  
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Apr 2021
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Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector Treg Cells

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  DOI: 10.1016/j.cmet.2020.10.022
  
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Genetically engineered myeloid cells rebalance the core immune suppression program in metastasis

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  DOI: 10.1016/j.cell.2021.02.048
  
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Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells

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  AB_2562451
  
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Feb 2021
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SARS-CoV-2 mRNA Vaccines Foster Potent Antigen-Specific Germinal Center Responses Associated with Neutralizing Antibody Generation

1
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Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade

1
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cell.com/cancer-cell/abstract/S1535-6108(20)30597-3
Oct 2020
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Resolving Fates and Single-Cell Transcriptomes of Hematopoietic Stem Cell Clones by PolyloxExpress Barcoding

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  DOI: 10.1016/j.stem.2020.07.018
  
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cell.com/cell-stem-cell/abstract/S1934-5909(20)30356-8
Sep 2020
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Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1β-Producing Myeloid Cells that Promote Pathogenic T Cells

1
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sciencedirect.com/science/article/pii/S1074761320300297
Jan 2020
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Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors

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  DOI: 10.1016/j.ccell.2019.10.008
  
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Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R−STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2562451
  
  DOI: 10.1016/j.immuni.2018.10.010
  
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