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ARAP2 regulates responses to interferon-gamma by restricting SOCS1

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  DOI: 10.1016/j.celrep.2025.116667
  
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sciencedirect.com:5037/science/article/pii/S2211124725014391
Sep 2025
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ZBP1 pathway promotes tumor immunogenicity in the combination of anti-HER2 therapy and epigenetic therapy

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  DOI: 10.1016/j.celrep.2025.116314
  
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sciencedirect.com/science/article/pii/S221112472501085X
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Elevated Transglutaminase-2 in SOX10-Deficient Melanoma Promotes Tumor Onset and Decreases Intratumoral CD4+ T Cells

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  DOI: 10.1158/0008-5472.CAN-24-3267
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12398951/
Aug 2025
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Tumor cell-intrinsic Decr2 regulates ferroptosis and immunotherapy efficacy

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  DOI: 10.1158/2326-6066.CIR-24-0519
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12314507/
Jul 2025
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Gasdermin-D-mediated epithelial-immune circuit synchronizes nutrient absorption and host defense in the small intestine

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  DOI: 10.1016/j.immuni.2025.06.019
  
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sciencedirect.com/science/article/pii/S1074761325003097
Jun 2025
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PDF-html.html

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52.53.155.43/b476b28c82bb83bd9fe4ec113cb042cd5e05e58b/PDF-html.html
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De-coupling immune parameters and toxicity associated with IL-12 agonism

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sciencedirect.com/science/article/pii/S2211124725006114
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Developmental epigenetic programming by Tet1/3 determines peripheral CD8 T cell fate

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  DOI: 10.1038/s44319-025-00439-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12116802/
Apr 2025
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Mitochondrial DNA released by senescent tumor cells enhances PMN-MDSC-driven immunosuppression through the cGAS-STING pathway

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CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cells

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1. scibot 08 Apr 2025
  
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  DOI: 10.7554/eLife.103417
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11970909/
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Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii

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  DOI: 10.1038/s41564-025-01967-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11964939/
Mar 2025
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Targeting tumor monocyte-intrinsic PD-L1 by rewiring STING signaling and enhancing STING agonist therapy

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1. scibot 11 Mar 2025
  
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  DOI: 10.1016/j.ccell.2025.02.014
  
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sciencedirect.com/science/article/pii/S1535610825000662
Feb 2025
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Tumor cell–intrinsic Piezo2 drives radioresistance by impairing CD8+ T cell stemness maintenance

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1. scibot 26 Feb 2025
  
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  DOI: 10.1084/jem.20231486
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11338319/
Dec 2024
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Deep profiling deconstructs features associated with memory CD8+ T cell tissue residence

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.007
  
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sciencedirect.com/science/article/pii/S1074761324005223
Nov 2024
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A modified BPaL regimen for tuberculosis treatment replaces linezolid with inhaled spectinamides

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1. scibot 07 Nov 2024
  
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  DOI: 10.7554/eLife.96190
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11460978/
Sep 2024
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H3K9 lactylation in malignant cells facilitates CD8+ T cell dysfunction and poor immunotherapy response

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1. scibot 04 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114686
  
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sciencedirect.com/science/article/pii/S2211124724010374
Aug 2024
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Application of a bespoke monoclonal antibody panel to characterize immune cell populations in cave nectar bats

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1. scibot 30 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114703
  
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sciencedirect.com/science/article/pii/S2211124724010544
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The acetyltransferase KAT7 is required for thymic epithelial cell expansion, expression of AIRE target genes, and thymic tolerance

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1. scibot 02 Aug 2024
  
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  DOI: 10.1126/sciimmunol.abb6032
  
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41467_2021_22885_MOESM1_ESM (1)-html.html

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  DOI: 10.1038/s41467-021-22885-8
  
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52.53.155.43/d779e06fb55038a9aa2d3318096423be7b35c53c/41467_2021_22885_MOESM1_ESM (1)-html.html
Jul 2024
www.cell.com www.cell.com

Anti-tumor efficacy of HRS-4642 and its potential combination with proteasome inhibition in KRAS G12D-mutant cancer

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cell.com/cancer-cell/abstract/S1535-6108(24)00226-5
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GRP75-dependent mitochondria-ER contacts ensure cell survival during early mouse thymocyte development

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  DOI: 10.1016/j.devcel.2024.06.007
  
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cell.com/developmental-cell/abstract/S1534-5807(24)00385-X
May 2024
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The latent stage of Toxoplasma gondii is targeted by the immune response and host protective

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  DOI: 10.1101/2024.03.05.583527
  
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biorxiv.org/content/10.1101/2024.03.05.583527v1
Feb 2024
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Unique immune profiles in Collaborative Cross mice linked to survival and viral clearance upon infection.

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  DOI: 10.1016/j.isci.2024.109103
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10867580/
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Combined blockade of VEGF, Angiopoietin-2, and PD1 reprograms glioblastoma endothelial cells into quasi-antigen-presenting cells

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1. scibot 14 Feb 2024
  
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  DOI: 10.1101/2022.09.03.506476
  
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52.53.155.43/ed5ac003e0303d13fddfbb7e3e68d91d0475a989/2022.09.03.506476v1.full-html.html
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Cell-intrinsic PD-L1 ablation sustains effector CD8+ T cell responses and promotes antitumor T cell therapy

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  DOI: 10.1016/j.celrep.2024.113712
  
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sciencedirect.com/science/article/pii/S2211124724000408
Jan 2024
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Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells

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sciencedirect.com/science/article/pii/S1534580723003945
Dec 2023
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Machine learning analysis of the T cell receptor repertoire identifies sequence features of self-reactivity

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sciencedirect.com/science/article/pii/S2405471223003277
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Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure

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sciencedirect.com/science/article/pii/S1074761323004879
Oct 2023
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Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation

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1. scibot 28 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113323
  
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NFAT5-dependent transcriptional stress control of endothelial cells prevents maladaptive remodeling of pulmonary arterioles in the hypoxic lung

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  DOI: 10.1101/2023.10.18.563022
  
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biorxiv.org/content/10.1101/2023.10.18.563022v1
Sep 2023
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STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1+ NK cells

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1. scibot 16 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113108
  
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sciencedirect.com/science/article/pii/S2211124723011191
Aug 2023
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Adrenergic nerves regulate intestinal regeneration through IL-22 signaling from type 3 innate lymphoid cells

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1. scibot 29 Aug 2023
  
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  DOI: 10.1016/j.stem.2023.07.013
  
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sciencedirect.com/science/article/pii/S1934590923002588
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Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells

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1. scibot 25 Aug 2023
  
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sciencedirect.com/science/article/pii/S1534580723003945
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Characterizing CD4 T cell differentiation in mouse small intestine using T cell transfer, lamina propria preparation, and flow cytometry

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1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.xpro.2023.102485
  
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Transplantation elicits a clonally diverse CD8+ T cell response that is comprised of potent CD43+ effectors

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Early immune pressure initiated by tissue-resident memory T cells sculpts tumor evolution in non-small cell lung cancer

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Accumulation of branched-chain amino acids reprograms glucose metabolism in CD8+ T cells with enhanced effector function and anti-tumor response

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A preclinical randomized controlled multi-centre trial of anti-interleukin-17A treatment for acute ischaemic stroke

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cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory

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IL-18BP mediates the balance between protective and pathological immune responses to Toxoplasma gondii

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GOT1 regulates CD8+ effector and memory T cell generation

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Mucosal exposure to non-tuberculous mycobacteria elicits B cell-mediated immunity against pulmonary tuberculosis

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Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells

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CEACAM1 is a direct SOX10 target and inhibits melanoma immune infiltration and stemness

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IgA deficiency destabilizes immunological homeostasis towards intestinal microbiota and increases the risk of systemic immune dysregulation

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Sep 2022
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Design, construction, and in vivo augmentation of a complex gut microbiome

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Dysbiosis in imiquimod-induced psoriasis alters gut immunity and exacerbates colitis development

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Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment

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Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer

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Mucosal chemokine adjuvant enhances synDNA vaccine-mediated responses to SARS-CoV-2 and provides heterologous protection in vivo

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Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity

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Nt5e deficiency does not affect post-stroke inflammation and lesion size in a murine ischemia/reperfusion stroke model

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Pre-existing chromatin accessibility and gene expression differences among naive CD4+ T cells influence effector potential

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Arthritis flares mediated by tissue-resident memory T cells in the joint

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Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis

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Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity

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Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer

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Untitled document

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May 2021
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Role of nuclear localization in the regulation and function of T-bet and Eomes in exhausted CD8 T cells

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Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector Treg Cells

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In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer

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Mar 2021
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Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer

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Temporal Analysis of Brd4 Displacement in the Control of B Cell Survival, Proliferation, and Differentiation

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Altered Immunity of Laboratory Mice in the Natural Environment Is Associated with Fungal Colonization

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FOXD3 Regulates VISTA Expression in Melanoma

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Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms

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Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity

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Rewilding Nod2 and Atg16l1 Mutant Mice Uncovers Genetic and Environmental Contributions to Microbial Responses and Immune Cell Composition

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Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4+ T Cells

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TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision

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1. scibot 13 Jan 2020
  
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  RRID:AB_2563056
  
  DOI: 10.1016/j.immuni.2019.09.013
  
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Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb

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1. scibot 13 Jan 2020
  
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  RRID:AB_2563056
  
  DOI: 10.1016/j.immuni.2019.10.001
  
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Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R−STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity

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1. scibot 13 Jan 2020
  
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  RRID:AB_2563056
  
  DOI: 10.1016/j.immuni.2018.10.010
  
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  Curator: @Jmenke
  
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The Chemoattractant Receptor Ebi2 Drives Intranodal Naive CD4+ T Cell Peripheralization to Promote Effective Adaptive Immunity

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1. scibot 13 Jan 2020
  
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  RRID:AB_2563056
  
  DOI: 10.1016/j.immuni.2019.04.001
  
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Nov 2018
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Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity

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1. scibot 05 Nov 2018
  
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Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR

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1. scibot 05 Nov 2018
  
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  RRID:AB_2563056
  
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Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2563056
  
  Curator: @evieth
  
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