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A stroma-sensing TGF-β blockade reprograms CAF-myeloid niches to induce durable tumor immunity

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1. scibot 14 Nov 2026
  
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  DOI: 10.1016/j.ccell.2026.10.007
  
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sciencedirect.com/science/article/pii/S1535610826004733
Nov 2026
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A hyper-IgM2 AID mutation limits IgH break formation but preserves affinity maturation

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1. scibot 05 Nov 2026
  
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  DOI: 10.1016/j.celrep.2026.118221
  
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sciencedirect.com/science/article/pii/S2211124726013008
Oct 2026
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Reversal of the neutrophil barrier for potentiating immune-engineered bacteria therapy in pancreatic cancer

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1. scibot 02 Oct 2026
  
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  DOI: 10.1016/j.xcrm.2026.103082
  
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sciencedirect.com/science/article/pii/S2666379126004994
Sep 2026
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Glutamine metabolism as a rheostat of CD4+ T cell pathogenic function in metabolic dysfunction-associated steatotic liver disease

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1. scibot 24 Sep 2026
  
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  DOI: 10.1016/j.cmet.2026.08.018
  
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sciencedirect.com/science/article/pii/S1550413126003700
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The long non-coding RNA-encoded microprotein MKKS3 drives colorectal cancer chemoresistance

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  DOI: 10.1038/s12276-026-01817-w
  
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  DOI: 10.1038/s12276-026-01817-w
  
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nature.com/articles/s12276-026-01817-w
Aug 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Genetically driven immune microenvironment states associate with therapeutic responses in MYD88 mutant lymphomas

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1. scibot 26 Aug 2026
  
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  DOI: 10.1186/s12943-026-02646-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13501595/
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Space radiation promotes clonal hematopoiesis and hematologic disease upon aging in a driver gene and sex-specific manner

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  DOI: 10.1016/j.isci.2026.116877
  
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sciencedirect.com/science/article/pii/S2589004226022558
Jul 2026
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Investigating the role of baseline gut Akkermansia muciniphila and its co-metabolite palmitoleic acid in BCG vaccine efficacy: a preclinical study

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1. scibot 25 Jul 2026
  
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  DOI: 10.1016/j.ebiom.2026.106404
  
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sciencedirect.com/science/article/pii/S2352396426002884
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A poly(I:C)/QS-21-based in situ vaccine synergizes with anti-PD-1 therapy to overcome tumor immunoresistance

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1. scibot 23 Jul 2026
  
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sciencedirect.com/science/article/pii/S2666379126003496
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RNA exonuclease REXO4 resolves m6A-marked R-loops and suppresses anti-tumor immunity

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1. scibot 21 Jul 2026
  
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  DOI: 10.1016/j.molcel.2026.06.036
  
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sciencedirect.com/science/article/pii/S1097276526004259
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METTL14 Enhances Anti-Tumor Immunity through m6A-dependent loss of PD-1

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1. scibot 11 Jul 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-0065
  
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aacrjournals.org/cancerres/article/85/21/4151/766750/METTL14-Enhances-Antitumor-Immunity-through-m6A
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Loss of SETD8 Impairs Mitochondrial Homeostasis to Suppress Leukemia Stem Cell Function in t(8;21) Acute Myeloid Leukemia

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1. scibot 11 Jul 2026
  
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  DOI: 10.1158/0008-5472.CAN-24-3659
  
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aacrjournals.org/cancerres/article/85/21/4122/766740/Loss-of-SETD8-Impairs-Mitochondrial-Homeostasis-to
May 2026
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Genotoxicity profiling reveals distinct platform-and cell type-specific effects in therapeutic gene editing for genetic hyperinflammation

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1. scibot 14 May 2026
  
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  DOI: 10.1016/j.stem.2026.04.014
  
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sciencedirect.com/science/article/pii/S1934590926001542
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VSIG4 restricts hepatocellular carcinoma control by suppressing tumor-specific CD8+ T cell immunity in the tumor microenvironment

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1. scibot 05 May 2026
  
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  DOI: 10.1158/2326-6066.CIR-25-0836
  
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aacrjournals.org/cancerimmunolres/article/14/5/718/784454/VSIG4-Restricts-Hepatocellular-Carcinoma-Control
Apr 2026
54.241.53.176 54.241.53.176

1-s2.0-S2589004226011764-main-html.html

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1. scibot 22 Apr 2026
  
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  AB_2563057
  
  DOI: 10.1016/j.isci.2026.115801
  
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54.241.53.176/8488015b440db33861248d6c24369f9587bf2f0a/1-s2.0-S2589004226011764-main-html.html
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Engineered oncolytic virus armed with anti-PCSK9 scFv boosts long-term CD8+ T cell immunity via rewiring MHC-I antigen presentation

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1. scibot 02 Apr 2026
  
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  DOI: 10.1016/j.xcrm.2026.102724
  
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sciencedirect.com/science/article/pii/S2666379126001412
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Distinct tissue niches contribute to prostate tissue-resident memory CD8+ T cell differentiation and heterogeneity

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1. scibot 02 Apr 2026
  
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  DOI: 10.1016/j.immuni.2026.03.003
  
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sciencedirect.com/science/article/pii/S1074761326001147
Mar 2026
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Regulatory T cell-derived TGF-β signaling governs the differentiation and maintenance of tumor-infiltrating bystander CD8+ T cells

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1. scibot 31 Mar 2026
  
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  DOI: 10.1016/j.celrep.2026.117189
  
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sciencedirect.com/science/article/pii/S2211124726002676
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Radiotherapy synergizes with an inducible AAV-based immunotherapy platform to program local and systemic antitumor immunity

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1. scibot 24 Mar 2026
  
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  DOI: 10.1016/j.ccell.2026.02.013
  
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Cancer cell-derived sialylated IgG interacting with Siglec-7/9/10 is a potential immunotherapeutic target in pancreatic cancer

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1. scibot 20 Mar 2026
  
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  DOI: 10.1016/j.xcrm.2026.102660
  
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sciencedirect.com/science/article/pii/S2666379126000777
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Oncolytic virotherapy potentiates chemo-PD-1 immunotherapy by engaging chemo-resistant bystander CD8+ T cells

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1. scibot 11 Mar 2026
  
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  DOI: 10.1136/jitc-2026-014897
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12970110/
Jan 2026
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MITA/STING-driven CD38 induction in Siglec-Flow macrophages promotes regulatory T cell survival and non-small cell lung cancer progression

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1. scibot 13 Jan 2026
  
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  DOI: 10.1016/j.devcel.2025.12.007
  
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DF6215, an α-optimized IL-2-Fc fusion, expands immune effectors and drives robust preclinical anti-tumor activity

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1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.xcrm.2025.102518
  
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sciencedirect.com/science/article/pii/S2666379125005919
Dec 2025
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Clonal persistence dominates homeostatic intestinal IgA responses

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1. scibot 04 Dec 2025
  
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  DOI: 10.1016/j.immuni.2025.11.005
  
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sciencedirect.com:5037/science/article/pii/S1074761325005072
Sep 2025
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Phenotypic pleiotropy of missense variants in human B cell confinement receptor P2RY8

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1. scibot 11 Sep 2025
  
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  DOI: 10.1016/j.xgen.2025.100981
  
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sciencedirect.com/science/article/pii/S2666979X2500237X
Aug 2025
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DNASE1L3-expressing dendritic cells promote CD8+ T cell function and anti-PD-(L)1 therapy efficacy by degrading neutrophil extracellular traps

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1. scibot 15 Aug 2025
  
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  DOI: 10.1016/j.ccell.2025.07.014
  
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cell.com/cancer-cell/abstract/S1535-6108(25)00320-4
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CD138 and APRIL regulate plasma cell survival, competition, and retention in the bone marrow niche

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1. scibot 06 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116123
  
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Polyamines regulate adaptive antitumor immunity by functional specialization of regulatory T cells

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  DOI: 10.1016/j.immuni.2025.07.007
  
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sciencedirect.com/science/article/pii/S1074761325003164
Jun 2025
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Targeting the CD40 costimulatory receptor to improve virotherapy efficacy in diffuse midline gliomas

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.xcrm.2025.102204
  
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sciencedirect.com/science/article/pii/S2666379125002770
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Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis

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1. scibot 11 Jun 2025
  
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  DOI: 10.1084/jem.20240109
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12139521/
May 2025
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Somatic hypermutation unlocks antibody specificities beyond the primary repertoire

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.014
  
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sciencedirect.com/science/article/pii/S1074761325001773
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Age-related impairment of intestinal inflammation resolution through an eicosanoid-immune-microbiota axis

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.chom.2025.04.014
  
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sciencedirect.com/science/article/pii/S1931312825001477
Apr 2025
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Protocol for investigating the impact of transcription regulator deficiency on tumor-specific CD8+ T cell responses via adoptive cell transfer

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1. scibot 03 Apr 2025
  
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  RRID:AB_2563057
  
  DOI: 10.1016/j.xpro.2025.103703
  
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sciencedirect.com/science/article/pii/S2666166725001091
Feb 2025
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NFAT single-deficient murine T cells reduce the risk of aGvHD while controlling cytomegalovirus infection

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1. scibot 13 Feb 2025
  
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  DOI: 10.1016/j.isci.2025.111937
  
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sciencedirect.com/science/article/pii/S258900422500197X
Jan 2025
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NFE2-driven neutrophil polarization promotes pancreatic cancer liver metastasis progression

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Targeting the mevalonate pathway potentiates NUAK1 inhibition-induced immunogenic cell death and antitumor immunity

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Targeted localization of the mother centrosome in CD8+ T cells undergoing asymmetric cell division promotes memory formation

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cir-24-0324-html.html

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A subset of neutrophils activates anti-tumor immunity and inhibits non-small-cell lung cancer progression

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A shorter splicing isoform antagonizes ZBP1 to modulate cell death and inflammatory responses

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The transcription regulator ID3 maintains tumor-specific memory CD8+ T cells in draining lymph nodes during tumorigenesis

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Application of a bespoke monoclonal antibody panel to characterize immune cell populations in cave nectar bats

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Lack of canonical thyroid hormone receptor α signaling changes regulatory T cell phenotype in female mice

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Spatiotemporal single-cell analysis decodes cellular dynamics underlying different responses to immunotherapy in colorectal cancer

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Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity

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The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation

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Claudin-2 upregulation enhances intestinal permeability, immune activation, dysbiosis, and mortality in sepsis

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Streptococcus agalactiae and Escherichia coli Induce Distinct Effector γδ T Cell Responses During Neonatal Sepsis

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QDPR deficiency drives immune suppression in pancreatic cancer

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Viral infection and spread are inhibited by the polyubiquitination and downregulation of TRPV2 channel by the interferon-stimulated gene TRIM21

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NR4a1/2 deletion promotes accumulation of TCF1+ stem-like precursors of exhausted CD8+ T cells in the tumor microenvironment

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Disruption of MerTK increases the efficacy of checkpoint inhibitor by enhancing ferroptosis and immune response in hepatocellular carcinoma

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Inflammatory dendritic cells restrain CD11b+CD4+ CTLs via CD200R in human NSCLC

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Peripheral MC1R Activation Modulates Immune Responses and is Neuroprotective in a Mouse Model of Parkinson’s Disease

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CD70-induced differentiation of proinflammatory Th1/17/22/GM lymphocytes associated with disease progression and immune reconstitution during HIV infection

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Resident regulatory T cells reflect the immune history of individual lymph nodes

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CD70-induced differentiation of proinflammatory Th1/17/22/GM lymphocytes associated with disease progression and immune reconstitution during HIV infection

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Protocol for cytokine and uterine immune cell characterization in a mouse model of LPS-induced preterm birth

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The dual lipid desaturase/hydroxylase DEGS2 controls phytoceramide levels necessary to counter intestinal inflammation

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CD39 inhibition and VISTA blockade may overcome radiotherapy resistance by targeting exhausted CD8+ T cells and immunosuppressive myeloid cells

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Jul 2023
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Lymph node medulla regulates the spatiotemporal unfolding of resident dendritic cell networks

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SSRN-id4411416-html.html

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Constitutively active autophagy in macrophages dampens inflammation through metabolic and post-transcriptional regulation of cytokine production

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Airway dysbiosis accelerates lung function decline in chronic obstructive pulmonary disease

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Asymmetric cell division safeguards memory CD8 T cell development

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BAFF and APRIL counterregulate susceptibility to inflammation-induced preterm birth

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Mar 2023
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A monoclonal Trd chain supports the development of the complete set of functional γδ T cell lineages

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NFATc1 induction by an intronic enhancer restricts NKT γδ cell formation

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Pregnancy-induced changes to the gut microbiota drive macrophage pyroptosis and exacerbate septic inflammation

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Small intestine and colon tissue-resident memory CD8+ T cells exhibit molecular heterogeneity and differential dependence on Eomes

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Neutrophil-activating therapy for the treatment of cancer

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In vivo G-CSF treatment activates the GR-SOCS1 axis to suppress IFN-γ secretion by natural killer cells

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Quantitative Increase in T Regulatory Cells Enhances Bone Remodeling in Osteogenesis Imperfecta

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Protocol to assess the tolerogenic properties of adoptively transferred dendritic cells during murine experimental autoimmune encephalomyelitis

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Optimal target saturation of ligand-blocking anti-GITR antibody IBI37G5 dictates FcγR-independent GITR agonism and antitumor activity

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Unravelling the sex-specific diversity and functions of adrenal gland macrophages

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Lymph node colonization induces tumor-immune tolerance to promote distant metastasis

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Negative Immune Checkpoint Protein, VISTA, Regulates the CD4+ Treg Population During Sepsis Progression to Promote Acute Sepsis Recovery and Survival

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JAK1 signaling in dendritic cells promotes peripheral tolerance in autoimmunity through PD-L1-mediated regulatory T cell induction

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The interplay between BAX and BAK tunes apoptotic pore growth to control mitochondrial-DNA-mediated inflammation

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Two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS-CoV-2 challenge

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Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation

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A TLR7 antagonist restricts interferon-dependent and -independent immunopathology in a mouse model of severe influenza

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Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection

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GPR34-mediated sensing of lysophosphatidylserine released by apoptotic neutrophils activates type 3 innate lymphoid cells to mediate tissue repair

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High Amount of Transcription Factor IRF8 Engages AP1-IRF Composite Elements in Enhancers to Direct Type 1 Conventional Dendritic Cell Identity

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Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity

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A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance

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Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy

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A Genome-wide CRISPR Screen Reveals a Role for the Non-Canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function

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Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) and Heptad Repeat (HR) of SARS-CoV-2 Elicit Robust Protective Immune Responses

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Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics

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Isotype Switching Converts Anti-CD40 Antagonism to Agonism to Elicit Potent Antitumor Activity

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Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population

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Untitled document

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Untitled document

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The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis-Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation

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KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity

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