Hypothesis

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Aug 2026
aacrjournals.org aacrjournals.org

DNA hypomethylating agents preserve T cell stemness and potentiate the efficacy of CD3-bispecific antibodies

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1. scibot 12 Aug 2026
  
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  AB_2563063
  
  DOI: 10.1158/2326-6066.CIR-25-1420
  
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aacrjournals.org/cancerimmunolres/article/14/8/1322/787178/DNA-Hypomethylating-Agents-Preserve-T-cell
Jul 2026
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AARS1 promotes tumor progression and immune evasion via ATF6 lactylation-mediated tryptophan metabolism in hepatocellular carcinoma

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1. scibot 03 Jul 2026
  
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  RRID:AB_2563063
  
  DOI: 10.1016/j.cmet.2026.06.003
  
  Resource: (BioLegend Cat# 106312, RRID:AB_2563063)
  
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sciencedirect.com/science/article/pii/S1550413126002299
Jan 2026
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Uridine depletion impairs CD8⁺ T cell antitumor activity through N-glycosylation

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1. scibot 06 Jan 2026
  
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  RRID:AB_2563063
  
  DOI: 10.1016/j.cmet.2025.11.016
  
  Resource: (BioLegend Cat# 106312, RRID:AB_2563063)
  
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sciencedirect.com/science/article/pii/S1550413125005303
Dec 2025
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Tumor-produced ammonia is metabolized by regulatory T cells to further impede anti-tumor immunity

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1. scibot 25 Dec 2025
  
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  RRID:AB_2563063
  
  DOI: 10.1016/j.cell.2025.11.034
  
  Resource: (BioLegend Cat# 106312, RRID:AB_2563063)
  
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sciencedirect.com/science/article/pii/S0092867425013698
May 2024
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Immunotherapy-activated T cells recruit and skewlate-stage activated M1-like macrophagesthat are critical for therapeutic efficacy

1
1. scibot 17 May 2024
  
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  RRID:AB_2563063
  
  DOI: 10.1016/j.ccell.2024.04.011
  
  Resource: (BioLegend Cat# 106312, RRID:AB_2563063)
  
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sciencedirect.com/science/article/pii/S1535610824001351
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Original research: Invasive margin tissue-resident macrophages of high CD163 expression impede responses to T cell-based immunotherapy

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1. scibot 18 Mar 2023
  
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  RRID:AB_2563063
  
  DOI: 10.1136/jitc-2022-006433
  
  Resource: (BioLegend Cat# 106312, RRID:AB_2563063)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10016286/
Jul 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Increased Expression of Multiple Co-Inhibitory Molecules on Malaria-Induced CD8+ T Cells Are Associated With Increased Function Instead of Exhaustion

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1. scibot 27 Jul 2022
  
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  AB_2563063
  
  DOI: 10.3389/fimmu.2022.878320
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9301332/
Jun 2022
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Tumor metabolite lactate promotes tumorigenesis by modulating MOESIN lactylation and enhancing TGF-β signaling in regulatory T cells

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1. scibot 22 Jun 2022
  
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  RRID:AB_2563063
  
  DOI: 10.1016/j.celrep.2022.110986
  
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sciencedirect.com/science/article/pii/S2211124722007720
Apr 2021
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Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector Treg Cells

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1. scibot 30 Apr 2021
  
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  RRID:AB_2563063
  
  DOI: 10.1016/j.cmet.2020.10.022
  
  Resource: (BioLegend Cat# 106312, RRID:AB_2563063)
  
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sciencedirect.com/science/article/pii/S155041312030591X
Sep 2020
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Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function

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1. scibot 11 Sep 2020
  
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  RRID:AB_2563063
  
  DOI: 10.1016/j.cmet.2020.03.004
  
  Resource: (BioLegend Cat# 106312, RRID:AB_2563063)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2563063
  
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  RRIDCUR:Validated RRID:AB_2563063
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RRID:AB_2563063

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sciencedirect.com/science/article/pii/S1550413120301194