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Engineering T Cells with a Tumor-Reactive Chimeric T Cell Receptor Reduces Exhaustion and Promotes Persistence to Elicit Enhanced Antitumor Responses

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1. scibot 11 Jul 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-0777
  
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aacrjournals.org/cancerres/article/86/11/2688/785304/Engineering-T-Cells-with-a-Tumor-Reactive-Chimeric
May 2026
www.science.org www.science.org

Disordered protein LAT encodes relative levels of signaling pathways in T cell activation

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1. scibot 08 May 2026
  
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  DOI: 10.1126/science.ads6847
  
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science.org/doi/10.1126/science.ads6847
Apr 2026
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Human immune aging clock identifies RUNX1 as a decelerator of T cell senescence

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1. scibot 16 Apr 2026
  
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  DOI: 10.1016/j.immuni.2026.02.007
  
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sciencedirect.com/science/article/pii/S1074761326000774
Feb 2026
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MafB is a conserved transcriptional regulator of macrophage development and functional identity across tissues and species

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1. scibot 27 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.012
  
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sciencedirect.com/science/article/pii/S1074761326000336
Jan 2026
www.cell.com www.cell.com

Remodeling of skull bone channels regulates immune infiltration into the meninges during neuroinflammation

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1. scibot 06 Jan 2026
  
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  DOI: 10.1016/j.immuni.2025.11.019
  
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cell.com/immunity/abstract/S1074-7613(25)00521-7
Oct 2025
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The transcriptional repressor BLIMP1 enforces TCF-1-dependent and -independent restriction of the memory fate of CD8+ T cells

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1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.immuni.2025.09.008
  
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sciencedirect.com/science/article/pii/S1074761325004194
Jun 2025
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Combined pharmacological targeting of CD9+ progenitors alleviates obesity-induced adipose tissue fibrosis and metabolic impairment

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1. scibot 18 Jun 2025
  
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  DOI: 10.1016/j.xcrm.2025.102197
  
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sciencedirect.com/science/article/pii/S2666379125002708
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis

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1. scibot 11 Jun 2025
  
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  DOI: 10.1158/2159-8290.CD-24-0093
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11611684/
May 2025
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Nociceptor neurons suppress alveolar macrophage-induced Siglec-F+ neutrophil-mediated inflammation to protect against pulmonary fibrosis

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1. scibot 31 May 2025
  
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  DOI: 10.1016/j.immuni.2025.05.002
  
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sciencedirect.com/science/article/pii/S1074761325002213
Apr 2025
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Type I interferons induce guanylate-binding proteins and lysosomal defense in hepatocytes to control malaria

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1. scibot 01 Apr 2025
  
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  DOI: 10.1016/j.chom.2025.03.008
  
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sciencedirect.com/science/article/pii/S1931312825000915
Mar 2025
www.cell.com www.cell.com

Mitochondria sense bacterial lactate and drive release of neutrophil extracellular traps

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1. scibot 07 Mar 2025
  
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  DOI: 10.1016/j.chom.2025.02.003
  
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cell.com/cell-host-microbe/abstract/S1931-3128(25)00051-4
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer’s disease mouse model

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1. scibot 08 Feb 2025
  
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  DOI: 10.1126/sciadv.adq6038
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11797491/
Dec 2023
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KDM5B predicts temozolomide-resistant subclones in glioblastoma

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1. scibot 20 Dec 2023
  
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  RRID:AB_2563202
  
  DOI: 10.1016/j.isci.2023.108596
  
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sciencedirect.com/science/article/pii/S2589004223026731
Oct 2023
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Epithelial restitution in 3D - Revealing biomechanical and physiochemical dynamics in intestinal organoids via fs laser nanosurgery

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1. scibot 17 Oct 2023
  
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  DOI: 10.1016/j.isci.2023.108139
  
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sciencedirect.com/science/article/pii/S2589004223022162
May 2023
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Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity

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1. scibot 27 May 2023
  
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  DOI: 10.1016/j.ccell.2023.04.016
  
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sciencedirect.com/science/article/pii/S1535610823001423
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cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity

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1. scibot 11 May 2023
  
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  DOI: 10.1016/j.immuni.2023.04.005
  
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sciencedirect.com/science/article/pii/S1074761323001735
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950

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1. scibot 20 Apr 2023
  
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  RRID:AB_2563202
  
  DOI: 10.1158/2767-9764.CRC-22-0310
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10112292/
Nov 2022
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The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity

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1. scibot 15 Nov 2022
  
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  RRID:AB_2563202
  
  DOI: 10.1016/j.immuni.2022.10.020
  
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sciencedirect.com/science/article/pii/S1074761322005611
Apr 2022
www.embopress.org www.embopress.org

Astrogenesis in the murine dentate gyrus is a life-long and dynamic process

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1. scibot 23 Apr 2022
  
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  DOI: 10.15252/embj.2021110409
  
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embopress.org/doi/abs/10.15252/embj.2021110409
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Quiescent cancer cells resist T cell attack by forming an immunosuppressive niche

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1. scibot 21 Apr 2022
  
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  DOI: 10.1016/j.cell.2022.03.033
  
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sciencedirect.com/science/article/pii/S0092867422003439
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Brown adipose tissue involution associated with progressive restriction in progenitor competence

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1. scibot 14 Apr 2022
  
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  AB_2563202
  
  DOI: 10.1016/j.celrep.2022.110575
  
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sciencedirect.com/science/article/pii/S2211124722003199
Nov 2021
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Effective chimeric antigen receptor T-cells (CAR-Ts) against SARS-CoV-2

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1. scibot 18 Nov 2021
  
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  DOI: 10.1016/j.isci.2021.103295
  
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sciencedirect.com/science/article/pii/S2589004221012645
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MiR-552-3p promotes malignant progression of gallbladder carcinoma by reactivating the Akt/β-catenin signaling pathway due to inhibition of the tumor suppressor gene RGMA

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1. scibot 05 Nov 2021
  
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  RRID:AB_2563202
  
  DOI: 10.21037/atm-21-2013
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8506546/
Jul 2021
bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com

Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types

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1. scibot 29 Jul 2021
  
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  RRID:AB_2563202
  
  DOI: 10.1186/s12915-018-0527-2
  
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  RRID:AB_2563202 RRIDCUR:Validated
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bmcbiol.biomedcentral.com/articles/10.1186/s12915-018-0527-2
May 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2

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1. scibot 27 May 2021
  
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  Cat#: 406414
  
  DOI: 10.1016/j.immuni.2021.05.006
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8106883/
Mar 2021
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Blockade of 6-phosphogluconate dehydrogenase generates CD8+ effector T cells with enhanced anti-tumor function

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1. scibot 10 Mar 2021
  
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  DOI: 10.1016/j.celrep.2021.108831
  
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sciencedirect.com/science/article/pii/S2211124721001455
Feb 2021
elifesciences.org elifesciences.org

The kinase PDK1 is critical for promoting T follicular helper cell differentiation

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1. scibot 25 Feb 2021
  
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  RRID:AB_2563202
  
  DOI: 10.7554/eLife.61406
  
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elifesciences.org/articles/61406
Jan 2020
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miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival

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1. scibot 13 Jan 2020
  
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  RRID:AB_2563202
  
  DOI: 10.1016/j.celrep.2019.07.064
  
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sciencedirect.com/science/article/pii/S2211124719309684
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IL-10-Dependent Crosstalk between Murine Marginal Zone B Cells, Macrophages, and CD8α+ Dendritic Cells Promotes Listeria monocytogenes Infection

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.immuni.2019.05.011
  
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sciencedirect.com/science/article/pii/S1074761319302316
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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.02.024
  
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sciencedirect.com/science/article/pii/S2211124719301949