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42 Matching Annotations

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CRISPR screens identify targets to rescue age-related T cell dysfunction in cancer

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1. scibot 01 Aug 2026
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.cell.2026.07.016
  
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sciencedirect.com/science/article/pii/S0092867426008147
May 2026
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miR-93-mediated PTEN suppression and CNS-specific T cell exhaustion shape the leukemia niche in infant KMT2A::AFF1+ B-ALL

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1. scibot 16 May 2026
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.celrep.2026.117353
  
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sciencedirect.com/science/article/pii/S2211124726004316
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Optimal CXCR5 expression during Tfh maturation involves the Bhlhe40-Pou2af1 axis

1
1. scibot 23 Oct 2025
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.celrep.2025.116470
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12744931/
Aug 2025
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Engineered T cells stimulate dendritic cell recruitment and antigen spreading for potent anti-tumor immunity

1
1. scibot 26 Aug 2025
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.xcrm.2025.102307
  
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sciencedirect.com/science/article/pii/S2666379125003805
Jul 2025
www.cell.com www.cell.com

TET2-mutant myeloid cells mitigate Alzheimer’s disease progression via CNS infiltration and enhanced phagocytosis in mice

1
1. scibot 10 Jul 2025
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.stem.2025.06.006
  
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cell.com/cell-stem-cell/fulltext/S1934-5909(25)00228-0
Jun 2025
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A hypomorphic Il2rb mutant mouse model recapitulates and reveals mechanisms of human T cell immune dysregulation in IL-2Rβ deficiency

1
1. scibot 26 Jun 2025
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.celrep.2025.115902
  
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sciencedirect.com/science/article/pii/S2211124725006734
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ILC3s sense gut microbiota through STING to initiate immune tolerance

1
1. scibot 17 Jun 2025
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.immuni.2025.05.016
  
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sciencedirect.com/science/article/pii/S1074761325002377
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

In vivo models of subclonal oncogenesis and dependency in hematopoietic malignancy

1
1. scibot 20 Nov 2024
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.ccell.2024.10.009
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11561369/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TUMOR-INFILTRATING NOCICEPTOR NEURONS PROMOTE IMMUNOSUPPRESSION

1
1. scibot 18 Sep 2024
  
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  AB_2563485
  
  DOI: 10.1101/2024.08.23.609450
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11382997/
Aug 2024
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LAG-3 sustains TOX expression and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity

1
1. scibot 20 Aug 2024
  
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  AB_2563485
  
  DOI: 10.1016/j.cell.2024.07.018
  
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sciencedirect.com/science/article/pii/S0092867424007785
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LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity

1
1. scibot 20 Aug 2024
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.cell.2024.07.016
  
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sciencedirect.com/science/article/pii/S0092867424007761
Jul 2024
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Notch2 signaling governs activated B cells to form memory B cells

1
1. scibot 12 Jul 2024
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.celrep.2024.114454
  
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sciencedirect.com/science/article/pii/S2211124724007836
May 2024
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The histone lysine methyltransferase MLL1 regulates the activation and functional specialization of regulatory T cells

1
1. scibot 14 May 2024
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.celrep.2024.114222
  
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sciencedirect.com/science/article/pii/S2211124724005503
Dec 2023
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Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18

1
1. scibot 17 Dec 2023
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.celrep.2023.113560
  
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sciencedirect.com/science/article/pii/S2211124723015723
Oct 2023
www.embopress.org www.embopress.org

IL-27 produced during acute malaria infection regulates Plasmodium-specific memory CD4+ T cells

1
1. scibot 20 Oct 2023
  
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  RRID:AB_2563485
  
  DOI: 10.15252/emmm.202317713
  
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embopress.org/doi/10.15252/emmm.202317713
Aug 2023
52.53.155.43 52.53.155.43

Hematopoietic stem and progenitor cells confer cross-protective trained immunity in mouse models

1
1. scibot 18 Aug 2023
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.isci.2023.107596
  
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52.53.155.43/d7b070e8e28224284f601b7e5624dab532af26cc/PIIS2589004223016735-html.html
Jun 2023
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Platelets and mast cells promote pathogenic eosinophil recruitment during invasive fungal infection via the 5-HIAA-GPR35 ligand-receptor system

1
1. scibot 07 Jun 2023
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.immuni.2023.05.006
  
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sciencedirect.com/science/article/pii/S1074761323002236
Mar 2023
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Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer

1
1. scibot 03 Mar 2023
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.ccell.2023.02.004
  
  Resource: (BioLegend Cat# 109841, RRID:AB_2563485)
  
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sciencedirect.com/science/article/pii/S1535610823000326
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

BATF2 promotes HSC myeloid differentiation by amplifying IFN response mediators during chronic infection

1
1. scibot 23 Feb 2023
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.isci.2023.106059
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9942003/
Jan 2023
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Small intestine and colon tissue-resident memory CD8+ T cells exhibit molecular heterogeneity and differential dependence on Eomes

1
1. scibot 28 Jan 2023
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.immuni.2022.12.007
  
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sciencedirect.com/science/article/pii/S1074761322006434
Nov 2022
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Prenatal inflammation perturbs murine fetal hematopoietic development and causes persistent changes to postnatal immunity

1
1. scibot 24 Nov 2022
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.celrep.2022.111677
  
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sciencedirect.com/science/article/pii/S2211124722015510
Oct 2022
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Influenza A virus infection instructs hematopoiesis to megakaryocyte-lineage output

1
1. scibot 05 Oct 2022
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.celrep.2022.111447
  
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sciencedirect.com/science/article/pii/S2211124722012888
Aug 2022
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Rapid GPR183-mediated recruitment of eosinophils to the lung after Mycobacterium tuberculosis infection

1
1. scibot 02 Aug 2022
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.celrep.2022.111144
  
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sciencedirect.com/science/article/pii/S2211124722009536
Jul 2022
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Diverging regulation of Bach2 protein and RNA expression determine cell fate in early B cell response

1
1. scibot 06 Jul 2022
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.celrep.2022.111035
  
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sciencedirect.com/science/article/pii/S2211124722008294
Mar 2022
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Coordinated changes in glycosylation regulate the germinal center through CD22

1
1. scibot 16 Mar 2022
  
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  RRID: AB_2563485
  
  DOI: 10.1016/j.celrep.2022.110512
  
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sciencedirect.com/science/article/pii/S2211124722002480
Feb 2022
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A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells

1
1. scibot 23 Feb 2022
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.molcel.2022.01.022
  
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sciencedirect.com/science/article/pii/S1097276522000879
Jan 2022
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TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures

1
1. scibot 12 Jan 2022
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.immuni.2021.12.007
  
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sciencedirect.com/science/article/pii/S1074761321005434
Sep 2021
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Follicular dendritic cells restrict interleukin-4 availability in germinal centers and foster memory B cell generation

1
1. scibot 23 Sep 2021
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.immuni.2021.08.028
  
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sciencedirect.com/science/article/pii/S1074761321003629
Jul 2021
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The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis

1
1. scibot 28 Jul 2021
  
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  CD45.2 BV605 (clone 104)
  
  DOI: 10.1016/j.immuni.2019.05.022
  
  Resource: (BioLegend Cat# 109841, RRID:AB_2563485)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1074761319302420
Jun 2021
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Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity

1
1. scibot 03 Jun 2021
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.cell.2021.05.021
  
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sciencedirect.com/science/article/pii/S0092867421006516
May 2021
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Chronic infection drives Dnmt3a-loss-of-function clonal hematopoiesis via IFNγ signaling

1
1. scibot 09 May 2021
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.stem.2021.03.002
  
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sciencedirect.com/science/article/pii/S1934590921001089
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Competition for Active TGFβ Cytokine Allows for Selective Retention of Antigen-Specific Tissue- Resident Memory T Cells in the Epidermal Niche

1
1. scibot 07 May 2021
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.immuni.2020.10.022
  
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sciencedirect.com/science/article/pii/S1074761320304635
Apr 2021
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Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis

1
1. scibot 22 Apr 2021
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.ccell.2020.10.012
  
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  Curator: @Naa003
  
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  RRIDCUR:Validated RRID:AB_2563485
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sciencedirect.com/science/article/pii/S1535610820305432
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UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability

1
1. scibot 15 Apr 2021
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.celrep.2021.108966
  
  Resource: (BioLegend Cat# 109841, RRID:AB_2563485)
  
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  RRID:AB_2563485 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124721002801
Feb 2021
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FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

1
1. scibot 27 Feb 2021
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.cell.2020.11.042
  
  Resource: (BioLegend Cat# 109841, RRID:AB_2563485)
  
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sciencedirect.com/science/article/pii/S0092867420316147
Dec 2020
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Interferon Gamma Mediates Hematopoietic Stem Cell Activation and Niche Relocalization through BST2

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1. scibot 23 Dec 2020
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.celrep.2020.108530
  
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sciencedirect.com/science/article/pii/S2211124720315199
Sep 2020
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The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection

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1. scibot 10 Sep 2020
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.celrep.2020.107827
  
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sciencedirect.com/science/article/pii/S2211124720308081
Jan 2020
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Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis

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1. scibot 13 Jan 2020
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.cmet.2019.10.006
  
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  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1550413119305613
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Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity

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1. scibot 13 Jan 2020
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.celrep.2019.09.065
  
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sciencedirect.com/science/article/pii/S2211124719312628
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Keratinocyte-Mediated Activation of the Cytokine TGF-β Maintains Skin Recirculating Memory CD8+ T Cells

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.immuni.2019.03.002
  
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JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells

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1. scibot 13 Jan 2020
  
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  RRID:AB_2563485
  
  DOI: 10.1016/j.ccell.2018.10.008
  
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  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S1535610818304744
Nov 2018
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Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations

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1. scibot 05 Nov 2018
  
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  RRID:AB_2563485
  
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