74 Matching Annotations
  1. May 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intratumoral virus-like particles containing a TLR9-agonist combined with systemic αPD-1 activate tumor-specific CD8+ T cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13133427/
  3. Apr 2026
  4. www.sciencedirect.com www.sciencedirect.com
    Distinct tissue niches contribute to prostate tissue-resident memory CD8+ T cell differentiation and heterogeneity
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    sciencedirect.com/science/article/pii/S1074761326001147
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    Sulfur partitioning from cysteine controls T cell proliferation and effector function
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    sciencedirect.com/science/article/pii/S0092867426002795
  6. Mar 2026
  7. 54.241.53.176 54.241.53.176
    2026.03.04.709484.full-html.html
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    54.241.53.176/8a248f7e0dd886c3327f74a873bf63f7a69ccf08/2026.03.04.709484.full-html.html
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    HIF-1α+ CD4+ T cells coordinate a tissue-resident immune cell network in the lung
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    sciencedirect.com/science/article/pii/S1074761326000452
  9. Feb 2026
  10. www.sciencedirect.com www.sciencedirect.com
    Immunodominance is a poor predictor of vaccine-induced T follicular helper cell quality
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    sciencedirect.com/science/article/pii/S2352396426000666
  11. www.sciencedirect.com www.sciencedirect.com
    Stochasticity in cancer immunotherapy stems from rare but functionally critical Spark T cells
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    sciencedirect.com/science/article/pii/S0092867425014394
  12. Jan 2026
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glycolysis inhibition functionally reprograms T follicular helper cells and reverses lupus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12812013/
  14. www.biorxiv.org www.biorxiv.org
    NF1 Loss Remodels Tumor Niches for Immune Evasion
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    biorxiv.org/content/10.64898/2026.01.11.698818v1
  15. Dec 2025
  16. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Opposing functions of distinct regulatory T cell subsets in colorectal cancer
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    sciencedirect.com:5037/science/article/pii/S1074761325005163
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RAS(ON) multi-selective inhibition drives antitumor immunity in preclinical models of NRAS-mutant melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12666865/
  18. Nov 2025
  19. www.sciencedirect.com www.sciencedirect.com
    StealTHY: An immunogen-free CRISPR platform to expose concealed metastasis regulators in immunocompetent models
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    sciencedirect.com/science/article/pii/S0092867425011365
  20. Oct 2025
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    Absence of BCAP in myeloid cells abrogates M2 macrophage differentiation and promotes anti-tumor immunity
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    sciencedirect.com/science/article/pii/S2589004225019844
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glucocorticoids unleash immune-dependent melanoma control through inhibition of the GARP/TGF-β axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC7618275/
  23. Sep 2025
  24. www.sciencedirect.com www.sciencedirect.com
    CD7 regulates the persistence of terminally exhausted CD8+ T cells during chronic infection
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    sciencedirect.com/science/article/pii/S2211124725010873
  25. www.sciencedirect.com www.sciencedirect.com
    Glycogen synthase kinase-3 is essential for Treg development and function
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    sciencedirect.com/science/article/pii/S2211124725010277
  26. www.sciencedirect.com www.sciencedirect.com
    Oxidative-stress-induced telomere instability drives T cell dysfunction in cancer
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    sciencedirect.com/science/article/pii/S1074761325003711
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Elevated Transglutaminase-2 in SOX10-Deficient Melanoma Promotes Tumor Onset and Decreases Intratumoral CD4+ T Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12398951/
  28. Aug 2025
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A RAS(ON) Multi-Selective Inhibitor Combination Therapy Triggers Long-term Tumor Control through Senescence-Associated Tumor-Immune Equilibrium in Pancreatic Ductal Adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12319406/
  30. Jul 2025
  31. www.sciencedirect.com www.sciencedirect.com
    Macropinocytosis maintains CAF subtype identity under metabolic stress in pancreatic cancer
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    sciencedirect.com/science/article/pii/S1535610825002715
  32. www.sciencedirect.com www.sciencedirect.com
    The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells
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    sciencedirect.com/science/article/pii/S1074761325002481
  33. www.sciencedirect.com www.sciencedirect.com
    Presentation of immunoregulatory sialoglycans on T cells is divergent between mice and humans
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    sciencedirect.com/science/article/pii/S2211124725007041
  34. Jun 2025
  35. www.sciencedirect.com www.sciencedirect.com
    Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8+ T cells
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    sciencedirect.com/science/article/pii/S1074761325002468
  36. www.sciencedirect.com www.sciencedirect.com
    MET pathway inhibition increases chemo-immunotherapy efficacy in small cell lung cancer
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    sciencedirect.com/science/article/pii/S2666379125002678
  37. May 2025
  38. www.sciencedirect.com www.sciencedirect.com
    Semaphorin7A and PD-L1 cooperatively drive immunosuppression during mammary involution and breast cancer
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    sciencedirect.com/science/article/pii/S2211124725004474
  39. Apr 2025
  40. www.sciencedirect.com www.sciencedirect.com
    Evolution of tumor stress response during cytoreductive surgery for ovarian cancer
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    sciencedirect.com/science/article/pii/S2589004225005784
  41. www.sciencedirect.com www.sciencedirect.com
    Pre-existing intratumoral stem-like CD8+ T cells drive radiotherapy-induced tumor immunity
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    sciencedirect.com/science/article/pii/S2211124725003377
  42. www.sciencedirect.com www.sciencedirect.com
    Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity
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    sciencedirect.com/science/article/pii/S0092867425002909
  43. 52.53.155.43 52.53.155.43
    Pre-existing intratumoral stem-like CD8+ T-cells drive radiotherapy-induced tumor control
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    52.53.155.43/ecad09cc9eabd42f0fef0391e2d71b5d66664c67/2024.10.16.618635.full-html.html
  44. www.sciencedirect.com www.sciencedirect.com
    Cancer-cell-derived cGAMP limits the activity of tumor-associated CD8+ T cells
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    sciencedirect.com/science/article/pii/S2211124725002815
  45. www.nature.com www.nature.com
    Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii
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    nature.com/articles/s41564-025-01967-z
  46. Mar 2025
  47. www.sciencedirect.com www.sciencedirect.com
    Inflammatory cytokines mediate the induction of and awakening from metastatic dormancy
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    sciencedirect.com/science/article/pii/S2211124725001597
  48. Feb 2025
  49. 52.53.155.43 52.53.155.43
    Glycolysis inhibition functionally reprograms T follicular helper cells and reverses lupus
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    52.53.155.43/e9b86e8ebe54b4f658c79e5de581ec84fce54015/2024.10.15.618563.full-html.html
  50. Jan 2025
  51. 52.53.155.43 52.53.155.43
    Maternal Immunoglobulin A regulates the development of the neonatal microbiota and intestinal microbiota-specific CD4+ T cell responses
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    52.53.155.43/5d9f175a1366852853c2411b63ad8211a7d72182/2024.06.10.598156v1.full-html.html
  52. www.sciencedirect.com www.sciencedirect.com
    Redirecting glucose flux during in vitro expansion generates epigenetically and metabolically superior T cells for cancer immunotherapy
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    sciencedirect.com/science/article/pii/S1550413124004893
  53. Aug 2024
  54. www.cell.com www.cell.com
    Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies
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    cell.com/cell/fulltext/S0092-8674(20)30163-X
  55. 52.53.155.43 52.53.155.43
    41467_2021_22885_MOESM1_ESM (1)-html.html
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    52.53.155.43/d779e06fb55038a9aa2d3318096423be7b35c53c/41467_2021_22885_MOESM1_ESM (1)-html.html
  56. Jul 2024
  57. www.sciencedirect.com www.sciencedirect.com
    Splenic marginal zone B cells restrict Mycobacterium tuberculosis infection by shaping the cytokine pattern and cell-mediated immunity
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    sciencedirect.com/science/article/pii/S2211124724007551
  58. www.sciencedirect.com www.sciencedirect.com
    Preclinical study and phase II trial of adapting low-dose radiotherapy to immunotherapy in small cell lung cancer
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    sciencedirect.com/science/article/pii/S2666634024002484
  59. www.sciencedirect.com www.sciencedirect.com
    Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors
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    sciencedirect.com/science/article/pii/S0092867424006536
  60. Jun 2024
  61. www.sciencedirect.com www.sciencedirect.com
    A CD36-dependent non-canonical lipid metabolism program promotes immune escape and resistance to hypomethylating agent therapy in AML
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    sciencedirect.com/science/article/pii/S2666379124002842
  62. May 2024
  63. www.biorxiv.org www.biorxiv.org
    The latent stage of Toxoplasma gondii is targeted by the immune response and host protective
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    biorxiv.org/content/10.1101/2024.03.05.583527v1
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect
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    ncbi.nlm.nih.gov/pmc/articles/PMC11082451/
  65. www.sciencedirect.com www.sciencedirect.com
    IL-7-primed bystander CD8 tumor-infiltrating lymphocytes optimize the antitumor efficacy of T cell engager immunotherapy
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    sciencedirect.com/science/article/pii/S2666379124002593
  66. Feb 2024
  67. www.sciencedirect.com www.sciencedirect.com
    Selection of epigenetically privileged HIV-1 proviruses during treatment with panobinostat and interferon-α2a
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    sciencedirect.com/science/article/pii/S0092867424001053
  68. www.sciencedirect.com www.sciencedirect.com
    Reversible, tunable epigenetic silencing of TCF1 generates flexibility in the T cell memory decision
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    sciencedirect.com/science/article/pii/S107476132300537X
  69. Nov 2023
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An essential role for miR-15/16 in Treg suppression and restriction of proliferation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10664750/
  71. Aug 2023
  72. www.biorxiv.org www.biorxiv.org
    TIM3 is a context-dependent co-regulator of cytotoxic T cell function
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    biorxiv.org/content/10.1101/2023.08.03.551797v1
  73. Jul 2023
  74. www.sciencedirect.com www.sciencedirect.com
    CD4+ T cells regulate sickness-induced anorexia and fat wasting during a chronic parasitic infection
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    sciencedirect.com/science/article/pii/S2211124723008252
  75. www.sciencedirect.com www.sciencedirect.com
    TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation
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    sciencedirect.com/science/article/pii/S1074761323002649
  76. May 2023
  77. www.sciencedirect.com www.sciencedirect.com
    Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma
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    sciencedirect.com/science/article/pii/S1535610823001368
  78. Apr 2023
  79. www.sciencedirect.com www.sciencedirect.com
    PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion
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    sciencedirect.com/science/article/pii/S2211124723004473
  80. www.sciencedirect.com www.sciencedirect.com
    Macrophage CD5L is a target for cancer immunotherapy
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    sciencedirect.com/science/article/pii/S2352396423001202
  81. Mar 2023
  82. www.sciencedirect.com www.sciencedirect.com
    T helper 2 cells control monocyte to tissue-resident macrophage differentiation during nematode infection of the pleural cavity
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    sciencedirect.com/science/article/pii/S1074761323000900
  83. Jan 2023
  84. www.sciencedirect.com www.sciencedirect.com
    CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor
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    sciencedirect.com/science/article/pii/S1074761322006069
  85. www.sciencedirect.com www.sciencedirect.com
    Neutrophil-activating therapy for the treatment of cancer
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    sciencedirect.com/science/article/pii/S1535610823000028
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Genome-wide screen identifies PDPK1 as a target to enhance the efficacy of MEK1/2 inhibitors in NRAS mutant melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9298960/
  87. Nov 2022
  88. www.sciencedirect.com www.sciencedirect.com
    Chronic type I interferon signaling promotes lipid-peroxidation-driven terminal CD8+ T cell exhaustion and curtails anti-PD-1 efficacy
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    sciencedirect.com/science/article/pii/S2211124722015182
  89. www.sciencedirect.com www.sciencedirect.com
    The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity
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    sciencedirect.com/science/article/pii/S1074761322005611
  90. Jan 2022
  91. www.sciencedirect.com www.sciencedirect.com
    Magnesium sensing via LFA-1 regulates CD8+ T cell effector function
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    sciencedirect.com/science/article/pii/S0092867421015610
  92. www.nature.com www.nature.com
    Adenosine 2A receptor and TIM3 suppress cytolytic killing of tumor cells via cytoskeletal polarization
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    nature.com/articles/s42003-021-02972-8
  93. www.sciencedirect.com www.sciencedirect.com
    Fine-tuning of MEK signaling is pivotal for limiting B and T cell activation
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    sciencedirect.com/science/article/pii/S2211124721017277
  94. Dec 2021
  95. www.sciencedirect.com www.sciencedirect.com
    Microbiota-specific T follicular helper cells drive tertiary lymphoid structures and anti-tumor immunity against colorectal cancer
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    sciencedirect.com/science/article/pii/S1074761321004945
  96. Aug 2021
  97. www.sciencedirect.com www.sciencedirect.com
    Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer
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    sciencedirect.com/science/article/pii/S0092867421008886
  98. May 2021
  99. www.sciencedirect.com www.sciencedirect.com
    Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy
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    sciencedirect.com/science/article/pii/S1074761320304003
  100. Apr 2021
  101. www.sciencedirect.com www.sciencedirect.com
    A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance
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    sciencedirect.com/science/article/pii/S1074761321001321
  102. Mar 2021
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-1 suppresses the maintenance of cell couples between cytotoxic T cells and target tumor cells within the tumor
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    ncbi.nlm.nih.gov/pmc/articles/PMC7784968/
  104. www.sciencedirect.com www.sciencedirect.com
    Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer
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    sciencedirect.com/science/article/pii/S1535610820306085
  105. Sep 2020
  106. www.cell.com www.cell.com
    Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies
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    cell.com/cell/fulltext/S0092-8674(20)30163-X
  107. Jan 2020
  108. www.sciencedirect.com www.sciencedirect.com
    Oncolytic Viruses Engineered to Enforce Leptin Expression, Reprogram Tumor-Infiltrating T Cell Metabolism, and Promote Tumor Clearance
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    sciencedirect.com/science/article/pii/S107476131930319X
  109. www.sciencedirect.com www.sciencedirect.com
    Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors
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    sciencedirect.com/science/article/pii/S1535610819304829
  110. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection
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    pmc.ncbi.nlm.nih.gov/articles/PMC6920571/
  111. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S1074761319301864