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    Opposing functions of distinct regulatory T cell subsets in colorectal cancer
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    sciencedirect.com:5037/science/article/pii/S1074761325005163
  3. Dec 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RAS(ON) multi-selective inhibition drives antitumor immunity in preclinical models of NRAS-mutant melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12666865/
  5. Nov 2025
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    StealTHY: An immunogen-free CRISPR platform to expose concealed metastasis regulators in immunocompetent models
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    sciencedirect.com/science/article/pii/S0092867425011365
  7. Oct 2025
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    Absence of BCAP in myeloid cells abrogates M2 macrophage differentiation and promotes anti-tumor immunity
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    sciencedirect.com/science/article/pii/S2589004225019844
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    Glucocorticoids unleash immune-dependent melanoma control through inhibition of the GARP/TGF-β axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC7618275/
  10. Sep 2025
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    CD7 regulates the persistence of terminally exhausted CD8+ T cells during chronic infection
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    Glycogen synthase kinase-3 is essential for Treg development and function
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    Oxidative-stress-induced telomere instability drives T cell dysfunction in cancer
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    Elevated Transglutaminase-2 in SOX10-Deficient Melanoma Promotes Tumor Onset and Decreases Intratumoral CD4+ T Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12398951/
  15. Aug 2025
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    A RAS(ON) Multi-Selective Inhibitor Combination Therapy Triggers Long-term Tumor Control through Senescence-Associated Tumor-Immune Equilibrium in Pancreatic Ductal Adenocarcinoma
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  17. Jul 2025
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    Macropinocytosis maintains CAF subtype identity under metabolic stress in pancreatic cancer
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    The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells
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    sciencedirect.com/science/article/pii/S1074761325002481
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    Presentation of immunoregulatory sialoglycans on T cells is divergent between mice and humans
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    sciencedirect.com/science/article/pii/S2211124725007041
  21. Jun 2025
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    Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8+ T cells
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    sciencedirect.com/science/article/pii/S1074761325002468
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    MET pathway inhibition increases chemo-immunotherapy efficacy in small cell lung cancer
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    sciencedirect.com/science/article/pii/S2666379125002678
  24. May 2025
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    Semaphorin7A and PD-L1 cooperatively drive immunosuppression during mammary involution and breast cancer
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    sciencedirect.com/science/article/pii/S2211124725004474
  26. Apr 2025
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    Evolution of tumor stress response during cytoreductive surgery for ovarian cancer
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    Pre-existing intratumoral stem-like CD8+ T cells drive radiotherapy-induced tumor immunity
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    sciencedirect.com/science/article/pii/S2211124725003377
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    Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity
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    Pre-existing intratumoral stem-like CD8+ T-cells drive radiotherapy-induced tumor control
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    Cancer-cell-derived cGAMP limits the activity of tumor-associated CD8+ T cells
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    Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii
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    pmc.ncbi.nlm.nih.gov/articles/PMC11964939/
  33. Mar 2025
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    Inflammatory cytokines mediate the induction of and awakening from metastatic dormancy
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  35. Feb 2025
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    Glycolysis inhibition functionally reprograms T follicular helper cells and reverses lupus
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  37. Jan 2025
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    Maternal Immunoglobulin A regulates the development of the neonatal microbiota and intestinal microbiota-specific CD4+ T cell responses
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    Redirecting glucose flux during in vitro expansion generates epigenetically and metabolically superior T cells for cancer immunotherapy
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  40. Aug 2024
  41. www.cell.com www.cell.com
    Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies
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    41467_2021_22885_MOESM1_ESM (1)-html.html
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  43. Jul 2024
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    Splenic marginal zone B cells restrict Mycobacterium tuberculosis infection by shaping the cytokine pattern and cell-mediated immunity
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    Preclinical study and phase II trial of adapting low-dose radiotherapy to immunotherapy in small cell lung cancer
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    Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors
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  47. Jun 2024
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    A CD36-dependent non-canonical lipid metabolism program promotes immune escape and resistance to hypomethylating agent therapy in AML
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  49. May 2024
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    The latent stage of Toxoplasma gondii is targeted by the immune response and host protective
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    biorxiv.org/content/10.1101/2024.03.05.583527v1
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    Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect
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    ncbi.nlm.nih.gov/pmc/articles/PMC11082451/
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    IL-7-primed bystander CD8 tumor-infiltrating lymphocytes optimize the antitumor efficacy of T cell engager immunotherapy
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  53. Feb 2024
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    Selection of epigenetically privileged HIV-1 proviruses during treatment with panobinostat and interferon-α2a
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    Reversible, tunable epigenetic silencing of TCF1 generates flexibility in the T cell memory decision
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  56. Nov 2023
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An essential role for miR-15/16 in Treg suppression and restriction of proliferation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10664750/
  58. Aug 2023
  59. www.biorxiv.org www.biorxiv.org
    TIM3 is a context-dependent co-regulator of cytotoxic T cell function
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    biorxiv.org/content/10.1101/2023.08.03.551797v1
  60. Jul 2023
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    CD4+ T cells regulate sickness-induced anorexia and fat wasting during a chronic parasitic infection
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    sciencedirect.com/science/article/pii/S2211124723008252
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    TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation
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    sciencedirect.com/science/article/pii/S1074761323002649
  63. May 2023
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    Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma
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    sciencedirect.com/science/article/pii/S1535610823001368
  65. Apr 2023
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    PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion
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    sciencedirect.com/science/article/pii/S2211124723004473
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    Macrophage CD5L is a target for cancer immunotherapy
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    sciencedirect.com/science/article/pii/S2352396423001202
  68. Mar 2023
  69. www.sciencedirect.com www.sciencedirect.com
    T helper 2 cells control monocyte to tissue-resident macrophage differentiation during nematode infection of the pleural cavity
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    sciencedirect.com/science/article/pii/S1074761323000900
  70. Jan 2023
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    CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor
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    sciencedirect.com/science/article/pii/S1074761322006069
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    Neutrophil-activating therapy for the treatment of cancer
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    sciencedirect.com/science/article/pii/S1535610823000028
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Genome-wide screen identifies PDPK1 as a target to enhance the efficacy of MEK1/2 inhibitors in NRAS mutant melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9298960/
  74. Nov 2022
  75. www.sciencedirect.com www.sciencedirect.com
    Chronic type I interferon signaling promotes lipid-peroxidation-driven terminal CD8+ T cell exhaustion and curtails anti-PD-1 efficacy
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    sciencedirect.com/science/article/pii/S2211124722015182
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    The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity
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    sciencedirect.com/science/article/pii/S1074761322005611
  77. Jan 2022
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    Magnesium sensing via LFA-1 regulates CD8+ T cell effector function
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    sciencedirect.com/science/article/pii/S0092867421015610
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    Adenosine 2A receptor and TIM3 suppress cytolytic killing of tumor cells via cytoskeletal polarization
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    nature.com/articles/s42003-021-02972-8
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    Fine-tuning of MEK signaling is pivotal for limiting B and T cell activation
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    sciencedirect.com/science/article/pii/S2211124721017277
  81. Dec 2021
  82. www.sciencedirect.com www.sciencedirect.com
    Microbiota-specific T follicular helper cells drive tertiary lymphoid structures and anti-tumor immunity against colorectal cancer
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    sciencedirect.com/science/article/pii/S1074761321004945
  83. Aug 2021
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    Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer
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    sciencedirect.com/science/article/pii/S0092867421008886
  85. May 2021
  86. www.sciencedirect.com www.sciencedirect.com
    Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy
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    sciencedirect.com/science/article/pii/S1074761320304003
  87. Apr 2021
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    A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance
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    sciencedirect.com/science/article/pii/S1074761321001321
  89. Mar 2021
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-1 suppresses the maintenance of cell couples between cytotoxic T cells and target tumor cells within the tumor
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    ncbi.nlm.nih.gov/pmc/articles/PMC7784968/
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    Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer
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    sciencedirect.com/science/article/pii/S1535610820306085
  92. Sep 2020
  93. www.cell.com www.cell.com
    Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies
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    cell.com/cell/fulltext/S0092-8674(20)30163-X
  94. Jan 2020
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    Oncolytic Viruses Engineered to Enforce Leptin Expression, Reprogram Tumor-Infiltrating T Cell Metabolism, and Promote Tumor Clearance
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    Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors
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    sciencedirect.com/science/article/pii/S1535610819304829
  97. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection
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    pmc.ncbi.nlm.nih.gov/articles/PMC6920571/
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    Untitled document
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