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Senescent T cells within the tumor microenvironment are a potent driver for tumor growth, stemness, and chemotherapy resistance

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  DOI: 10.1016/j.xcrm.2026.103141
  
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sciencedirect.com/science/article/pii/S2666379126005586
Oct 2026
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A Full Spectrum Fibroblast Profiling Panel Reveals Phenotypic and Metabolic Heterogeneity of Cancer-Associated Fibroblasts at the Single-Cell Level

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1. scibot 12 Oct 2026
  
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  DOI: 10.64898/2026.09.07.749987
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13622700/
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Induced regulatory B cells stably expressing interleukin-10 reverse central nervous system autoimmunity by targeting myeloid cells

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1. scibot 08 Oct 2026
  
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  DOI: 10.1016/j.immuni.2026.09.006
  
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sciencedirect.com/science/article/pii/S107476132600381X
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In vivo-edited CCR7+IL-7+ DCs reverse T cell exhaustion by promoting T memory stem cell differentiation

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1. scibot 02 Oct 2026
  
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  DOI: 10.1016/j.xcrm.2026.103086
  
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sciencedirect.com/science/article/pii/S2666379126005033
Sep 2026
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Combining pro-resolving therapy with cyclosporine A restores immune homeostasis and reduces toxicity in autoimmune bone marrow failure

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1. scibot 27 Sep 2026
  
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sciencedirect.com/science/article/pii/S266637912600491X
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CD4 T cells convert transient responses to KRAS inhibition to durable remissions in pancreatic cancer

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1. scibot 27 Sep 2026
  
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  DOI: 10.1016/j.cell.2026.08.045
  
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sciencedirect.com/science/article/pii/S0092867426010184
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P2X7R+CD8αβ+ T cells exacerbate postoperative ileus by inducing the loss of enterochromaffin cells

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1. scibot 19 Sep 2026
  
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sciencedirect.com/science/article/pii/S2589004226028701
Aug 2026
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Core activation program and selective regional responsiveness of microglia during aging and parabiosis

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1. scibot 30 Aug 2026
  
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sciencedirect.com/science/article/pii/S2211124726009976
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Moxibustion Promotes Tumor Immune Responses and Vascular Normalization to Enhance Antitumor Effect of Cisplatin in Lewis Lung Carcinoma Mice

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1. scibot 24 Aug 2026
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13498794/
Jul 2026
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A MERTK-Targeting Antibody-Drug Conjugate Selectively Depletes M2 Tumor-Associated Macrophages and MERTK-Expressing Cancer Cells

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1. scibot 12 Jul 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-2998
  
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aacrjournals.org/cancerres/article/86/8/2024/782620/A-MERTK-Targeting-Antibody-Drug-Conjugate
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Protocol for inducing deep vein thrombosis in C57BL/6J mice using the inferior vena cava stenosis model

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1. scibot 07 Jul 2026
  
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  DOI: 10.1016/j.xpro.2026.104665
  
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sciencedirect.com/science/article/pii/S2666166726003187
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Targeting cholesterol esterification sensitizes liver cancer to CD8+ T cell attack by impairing metabolic and redox resilience

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1. scibot 07 Jul 2026
  
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  DOI: 10.1016/j.immuni.2026.06.002
  
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A single Citrobacter rodentium infection in Pink1 knockout and wild-type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss

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1. scibot 03 Jul 2026
  
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  DOI: 10.1371/journal.ppat.1014315
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13318054/
Jun 2026
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NRF2-mediated inhibition of alveolar macrophage MHC II expression during Mycobacterium tuberculosis infection

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1. scibot 05 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117397
  
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sciencedirect.com/science/article/pii/S2211124726004754
May 2026
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Nociceptive innervation limits tertiary lymphoid structures to promote lung cancer

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1. scibot 20 May 2026
  
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  DOI: 10.1016/j.cell.2026.04.038
  
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sciencedirect.com/science/article/pii/S0092867426005052
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Dendritic cell redundancy enables priming of anti-tumor CD4+ T cells in pancreatic cancer

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1. scibot 08 May 2026
  
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  DOI: 10.1016/j.ccell.2026.04.005
  
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sciencedirect.com/science/article/pii/S1535610826002163
Apr 2026
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Innate lymphoid cells integrate sensing and plasticity to control fungal infections

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1. scibot 24 Apr 2026
  
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  DOI: 10.1016/j.celrep.2026.117140
  
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sciencedirect.com/science/article/pii/S2211124726002184
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A Rasa3-Gαi signaling axis orchestrates B lymphocyte trafficking into and through lymphoid organs

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1. scibot 11 Apr 2026
  
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  DOI: 10.1016/j.celrep.2026.117243
  
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sciencedirect.com/science/article/pii/S2211124726003219
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Integrin-dependent neutrophil slowing reduces lung perfusion and supports metastasis in a model of breast cancer

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1. scibot 11 Apr 2026
  
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  DOI: 10.1016/j.celrep.2026.117101
  
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sciencedirect.com/science/article/pii/S2211124726001798
Mar 2026
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Reshaping the progranulin/sortilin interaction for targeted degradation of extracellular proteins

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1. scibot 31 Mar 2026
  
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  DOI: 10.1016/j.chembiol.2026.03.002
  
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sciencedirect.com/science/article/pii/S2451945626000723
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Insufficient erythrocyte-derived S1P: A pathogenic driver and diagnostic biolipid for tumor progression

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1. scibot 24 Mar 2026
  
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  DOI: 10.1016/j.isci.2026.115216
  
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sciencedirect.com/science/article/pii/S2589004226005912
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GPX4 Inhibitor Resistance and Metastatic Features in Triple-Negative Breast Cancer

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1. scibot 05 Mar 2026
  
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  DOI: 10.1002/advs.202523198
  
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advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202523198
Feb 2026
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dzierlega-et-al-2026-neutrophil-derived-reactive-oxygen-species-mediate-doxorubicin-induced-cardiotoxicity-and-skeletal-html.html

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1. scibot 26 Feb 2026
  
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  DOI: 10.17632/2d8stp2tpg.1
  
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54.241.53.176/5c0cd9870eff9fe6eac9da642db1e945f1461ca7/dzierlega-et-al-2026-neutrophil-derived-reactive-oxygen-species-mediate-doxorubicin-induced-cardiotoxicity-and-skeletal-html.html
Jan 2026
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Aromatic microbial metabolite hippuric acid enhances inflammatory responses in macrophages via TLR-MyD88 signaling and lipid remodeling

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  DOI: 10.1016/j.celrep.2025.116749
  
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sciencedirect.com/science/article/pii/S2211124725015219
Dec 2025
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Tumor-produced ammonia is metabolized by regulatory T cells to further impede anti-tumor immunity

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1. scibot 25 Dec 2025
  
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  RRID:AB_B433930
  
  DOI: 10.1016/j.cell.2025.11.034
  
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Dysplastic epithelial repair promotes the tissue residence of lymphocytes to inhibit alveolar regeneration post viral infection

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1. scibot 23 Dec 2025
  
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  DOI: 10.1016/j.stem.2025.12.005
  
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sciencedirect.com/science/article/pii/S1934590925004394
Oct 2025
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Cannabidivarin directly targets the immunosuppressive activity of regulatory myeloid cells in tumors

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1. scibot 28 Oct 2025
  
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  DOI: 10.1016/j.biopha.2025.118697
  
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sciencedirect.com/science/article/pii/S0753332225008911
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Local delivery of IL-15 and anti-PD-L1 nanobody by in vitro-transcribed circILNb elicits superior antitumor immunity in cold tumors

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1. scibot 11 Oct 2025
  
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  DOI: 10.1016/j.xcrm.2025.102413
  
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sciencedirect.com/science/article/pii/S2666379125004860
Aug 2025
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Fibroblast bioelectric signaling drives hair growth

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1. scibot 19 Aug 2025
  
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  DOI: 10.1016/j.cell.2025.07.035
  
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sciencedirect.com/science/article/pii/S0092867425008578
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Scavenger Receptor CD36 in Tumor-Associated Macrophages Promotes Cancer Progression by Dampening Type I Interferon Signaling

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1. scibot 05 Aug 2025
  
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  DOI: 10.1158/0008-5472.CAN-23-4027
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11788022/
Jul 2025
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Targeting Triple-Negative Breast Cancer with Momordicine-I for Therapeutic Gain in Preclinical Models

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1. scibot 22 Jul 2025
  
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  DOI: 10.3390/cancers17142342
  
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mdpi.com/2072-6694/17/14/2342
Jun 2025
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VISTA immune checkpoint blunts radiotherapy-induced antitumor immune response

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115893
  
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sciencedirect.com/science/article/pii/S2211124725006643
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FGF21 promotes longevity in diet-induced obesity through metabolic benefits independent of growth suppression

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1. scibot 17 Jun 2025
  
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  DOI: 10.1016/j.cmet.2025.05.011
  
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sciencedirect.com/science/article/pii/S1550413125002670
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Major-depressive-disorder-associated dysregulation of ZBTB7A in orbitofrontal cortex promotes astrocyte-mediated stress susceptibility

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1. scibot 14 Jun 2025
  
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  RRID:AB_2564383
  
  DOI: 10.1016/j.neuron.2025.05.023
  
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cell.com/neuron/fulltext/S0896-6273(25)00394-0
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Trametinib potentiates anti-PD-1 efficacy in tumors established from chemotherapy-primed pancreatic cancer cells

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1. scibot 11 Jun 2025
  
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  RRID:AB_2564383
  
  DOI: 10.1158/1535-7163.MCT-23-0833
  
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Glucose-1-phosphate promotes compartmentalization of glycogen with the pentose phosphate pathway in CD8+ memory T cells

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Preferential tumor targeting of HER2 by iPSC-derived CAR T cells engineered to overcome multiple barriers to solid tumor efficacy

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Myeloperoxidase impacts vascular function by altering perivascular adipocytes’ secretome and phenotype in obesity

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PDF-html.html

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Interferon-gamma receptor signaling regulates innate immunity during Staphylococcus aureus craniotomy infection

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Trained immunity is regulated by T cell-induced CD40-TRAF6 signaling

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An inducible genetic tool to track and manipulate specific microglial states reveals their plasticity and roles in remyelination

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EGFR-driven lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth

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Targeting branched N-glycans and fucosylation sensitizes ovarian tumors to immune checkpoint blockade

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Gut epithelial Interleukin-17 receptor A signaling can modulate distant tumors growth through microbial regulation

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Staphylococcus epidermidis activates keratinocyte cytokine expression and promotes skin inflammation through the production of phenol-soluble modulins

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Myeloid-intrinsic cell cycle-related kinase drives immunosuppression to promote tumorigenesis

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CTLA-4 blockade induces CD4+ T cell IFNγ-driven microglial phagocytosis and anti-tumor function in glioblastoma

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CD4+ T cells regulate sickness-induced anorexia and fat wasting during a chronic parasitic infection

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SFTSV infection is associated with transient overproliferation of monoclonal lambda-type plasma cells

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EGFR+ lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth

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Original research: Targeting tumor vasculature to improve antitumor activity of T cells armed ex vivo with T cell engaging bispecific antibody

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IFNγ is a central node of cancer immune equilibrium

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Adipocyte-Secreted IL-6 Sensitizes Macrophages to IL-4 Signaling

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KDM5A Inhibits Antitumor Immune Responses Through Downregulation of the Antigen-Presentation Pathway in Ovarian Cancer

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Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria

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The matricellular protein SPARC induces inflammatory interferon-response in macrophages during aging

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Rapid GPR183-mediated recruitment of eosinophils to the lung after Mycobacterium tuberculosis infection

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cir-22-0088-html.html

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The SETDB1–TRIM28 complex suppresses antitumor immunity

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Inhibition of CDK4/6 promotes CD8 T cell memory formation

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Mar 2022
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Mucus sialylation determines intestinal host-commensal homeostasis

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Blood-brain barrier-restricted translocation of Toxoplasma gondii from cortical capillaries

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Dec 2021
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Macrophages transfer mitochondria to sensory neurons to resolve inflammatory pain

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Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis

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Modulating tumor infiltrating myeloid cells to enhance bispecific antibody-driven T cell infiltration and anti-tumor response

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IL-33 causes thermogenic failure in aging by expanding dysfunctional adipose ILC2

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Jul 2021
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Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice

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1. scibot 08 Jul 2021
  
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  RRID:AB_2564383
  
  DOI: 10.7554/eLife.66522
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8245129/
Jun 2021
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors

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1. scibot 08 Jun 2021
  
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  RRID:AB_2564383
  
  DOI: 10.1016/j.immuni.2021.05.003
  
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pmc.ncbi.nlm.nih.gov/articles/PMC9273026/
Apr 2021
www.cell.com www.cell.com

Diet Diurnally Regulates Small Intestinal Microbiome-Epithelial-Immune Homeostasis and Enteritis

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1. scibot 24 Apr 2021
  
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  RRID:AB_2564383
  
  DOI: 10.1016/j.cell.2020.08.027
  
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cell.com/cell/fulltext/S0092-8674(20)31069-2
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Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis

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1. scibot 11 Apr 2021
  
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  RRID:AB_2564383
  
  DOI: 10.1016/j.cell.2021.01.049
  
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sciencedirect.com/science/article/pii/S0092867421000921
Nov 2020
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Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity

1
1. scibot 24 Nov 2020
  
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  Brilliant Violet 711 anti-mouse CD45 Antibody (clone 30F11)
  
  DOI: 10.1016/j.celrep.2020.108381
  
  Resource: (BioLegend Cat# 103147, RRID:AB_2564383)
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S221112472031370X
Sep 2020
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Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1β-Producing Myeloid Cells that Promote Pathogenic T Cells

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1. scibot 16 Sep 2020
  
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  RRID:AB_2564383
  
  DOI: 10.1016/j.immuni.2020.01.002
  
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  RRIDCUR:Validated RRID:AB_2564383
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sciencedirect.com/science/article/pii/S1074761320300297
Jan 2020
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Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence

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1. scibot 13 Jan 2020
  
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  RRID:AB_2564383
  
  DOI: 10.1016/j.cell.2019.08.012
  
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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge

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1. scibot 13 Jan 2020
  
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  RRID:AB_2564383
  
  DOI: 10.1016/j.immuni.2019.10.010
  
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pmc.ncbi.nlm.nih.gov/articles/PMC6892583/
Nov 2018
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T Cells in Nonlymphoid Tissues Give Rise to Lymph-Node-Resident Memory T Cells

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1. scibot 05 Nov 2018
  
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  RRID:AB_2564383
  
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sciencedirect.com/science/article/pii/S1074761318300360

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