90 Matching Annotations
  1. Last 7 days
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    SARS-CoV-2 infection exacerbates the cellular pathology of Parkinson’s disease in human dopaminergic neurons and a mouse model
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    sciencedirect.com/science/article/pii/S2666379124002623
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    Mouse α-synuclein fibrils are structurally and functionally distinct from human fibrils associated with Lewy body diseases
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      DOI: 10.1101/2024.05.09.593334

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    biorxiv.org/content/10.1101/2024.05.09.593334v1
  4. Apr 2024
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    Human spinal GABA neurons alleviate spasticity and improve locomotion in rats with spinal cord injury
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    sciencedirect.com/science/article/pii/S2211124721002035
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    Olfactory bulb anomalies in KBG syndrome mouse model and patients
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    ncbi.nlm.nih.gov/pmc/articles/PMC11017579/
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    Cnicin promotes functional nerve regeneration
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    sciencedirect.com/science/article/pii/S0944711324003003
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    Parasympathetic neurons derived from human pluripotent stem cells model human diseases and development
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    Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
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    nature.com/articles/s41419-024-06534-8
  10. Mar 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TEAD1 is crucial for developmental myelination, Remak bundles, and functional regeneration of peripheral nerves
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      DOI: 10.7554/eLife.87394

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959528/
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    Local mitochondrial replication in the periphery of neurons requires the eEF1A1 protein and thetranslation of nuclear-encoded proteins
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    Alternative splicing decouples local from global PRC2 activity
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    sciencedirect.com/science/article/pii/S1097276524001308
  14. Feb 2024
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    Neuronal reprogramming of mouse and human fibroblasts using transcription factors involved in suprachiasmatic nucleus development
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    sciencedirect.com/science/article/pii/S2589004224002724
  16. Jan 2024
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    Protocol for the isolation and culture of microglia, astrocytes, and neurons from the same mouse brain
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    1. scibot 18 Jan 2024
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      DOI: 10.1016/j.xpro.2023.102804

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    sciencedirect.com/science/article/pii/S2666166723007712
  18. Dec 2023
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    Characterization of two human induced pluripotent stem cell lines derived from Batten disease patient fibroblasts harbouring CLN5 mutations
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    Mir324 knockout regulates the structure of dendritic spines and impairs hippocampal long-term potentiation
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      DOI: 10.1038/s41598-023-49134-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC10713680/
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    Phase I clinical trial of intracerebroventricular transplantation of allogeneic neural stem cells in people with progressive multiple sclerosis
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    sciencedirect.com/science/article/pii/S1934590923003934
  22. Nov 2023
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    Loss of Baz1b in mice causes perinatal lethality, growth failure, and variable multi-system outcomes
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    sciencedirect.com/science/article/pii/S0012160623001616
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    APOE4-promoted gliosis and degeneration in tauopathy are ameliorated by pharmacological inhibition of HMGB1 release
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    sciencedirect.com/science/article/pii/S2211124723012640
  25. Oct 2023
  26. www.nature.com www.nature.com
    Chromatin-modifying enzymes as modulators of nuclear size during lineage differentiation
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    nature.com/articles/s41420-023-01639-z
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    Three-dimensional reconstructions of mechanosensory end organs suggest a unifying mechanism underlying dynamic, light touch
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    sciencedirect.com/science/article/pii/S0896627323006347
  28. Sep 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    One-step cell biomanufacturing platform: porous gelatin microcarrier beads promote human embryonic stem cell-derived midbrain dopaminergic progenitor cell differentiation in vitro and survival after transplantation in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC10503631/
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    Human iPS cell-derived sensory neurons can be infected by SARS-CoV-2
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    1. scibot 07 Sep 2023
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    sciencedirect.com/science/article/pii/S2589004223017674
  31. Aug 2023
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    DRG afferents that mediate physiologic and pathologic mechanosensation from the distal colon
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    sciencedirect.com/science/article/pii/S0092867423007407
  33. Jul 2023
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Estradiol- and Progesterone-Associated Changes in microRNA-Induced Silencing and Reduced Antiseizure Efficacy of an Antagomir in Female Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10368146/
  35. Jun 2023
  36. anatomypubs.onlinelibrary.wiley.com anatomypubs.onlinelibrary.wiley.com
    A framework to identify functional interactors that contribute to disrupted early retinal development in Vsx2 ocular retardation J mice
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      DOI: 10.1002/dvdy.629

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    anatomypubs.onlinelibrary.wiley.com/doi/10.1002/dvdy.629
  37. May 2023
  38. www.sciencedirect.com www.sciencedirect.com
    Prox2 and Runx3 vagal sensory neurons regulate esophageal motility
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      DOI: 10.1016/j.neuron.2023.04.025

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    sciencedirect.com/science/article/pii/S089662732300332X
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    Methods for culturing adult CNS neurons reveal a CNS conditioning effect
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      DOI: 10.1016/j.crmeth.2022.100255

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    sciencedirect.com/science/article/pii/S266723752200128X
  40. Mar 2023
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    Generation of a PDGFRB-mCherry knock-in reporter human induced pluripotent stem cell line (KITi001-A-1), using CRISPR/Cas9 nuclease
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    sciencedirect.com/science/article/pii/S1873506123000673
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    The P-body protein 4E-T represses translation to regulate the balance between cell genesis and establishment of the postnatal NSC pool
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      DOI: 10.1016/j.celrep.2023.112242

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    sciencedirect.com/science/article/pii/S221112472300253X
  43. Feb 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Generation of telomeric repeat binding factor 1 (TRF1)-knockout human embryonic stem cell lines, KRIBBe010-A-95, KRIBBe010-A-96, and KRIBBe010-A-97, using CRISPR/Cas9 technology
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    sciencedirect.com/science/article/pii/S1873506123000314
  45. Jan 2023
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    Epiblast-like stem cells established by Wnt/β-catenin signaling manifest distinct features of formative pluripotency and germline competence
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    sciencedirect.com/science/article/pii/S2211124723000323
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    Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons
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    sciencedirect.com/science/article/pii/S1934590922004945
  48. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Brain-derived neurotrophic factor (BDNF) induces antagonistic action to Nogo signaling by the upregulation of lateral olfactory tract usher substance (LOTUS) expression
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      DOI: 10.1111/jnc.15732

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15732
  49. www.sciencedirect.com www.sciencedirect.com
    Human cortical interneurons optimized for grafting specifically integrate, abort seizures, and display prolonged efficacy without over-inhibition
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      DOI: 10.1016/j.neuron.2022.12.014

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    sciencedirect.com/science/article/pii/S089662732201087X
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    Culture Protocol and Transcriptomic Analysis of Murine SVZ NPCs and OPCs
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      DOI: 10.1007/s12015-022-10492-z

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    link.springer.com/article/10.1007/s12015-022-10492-z
  51. Dec 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Generation of human elongating multi-lineage organized cardiac gastruloids
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      DOI: 10.1016/j.xpro.2022.101898

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    sciencedirect.com/science/article/pii/S266616672200778X
  53. www.sciencedirect.com www.sciencedirect.com
    Establishment of a human embryonic stem cell line, WAe009-A-99, with constitutive expression of the dCas9-p300 fusion protein
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    1. scibot 01 Dec 2022
      RRID:AB_2564645Millipore

      DOI: 10.1016/j.scr.2022.102986

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    sciencedirect.com/science/article/pii/S187350612200335X
  54. Nov 2022
  55. www.sciencedirect.com www.sciencedirect.com
    Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis
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    1. scibot 16 Nov 2022
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      DOI: 10.1016/j.neuron.2022.10.028

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    sciencedirect.com/science/article/pii/S0896627322009618
  56. Oct 2022
  57. www.sciencedirect.com www.sciencedirect.com
    Targeting RTN4/NoGo-Receptor reduces levels of ALS protein ataxin-2
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    1. scibot 26 Oct 2022
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      DOI: 10.1016/j.celrep.2022.111505

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    sciencedirect.com/science/article/pii/S2211124722013559
  58. Sep 2022
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of neuronal injury transcriptional response identifies CTCF and YY1 as co-operating factors regulating axon regeneration
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      DOI: 10.3389/fnmol.2022.967472

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  60. Aug 2022
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    Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer’s disease
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  62. Jul 2022
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    Pharmacotherapy alleviates pathological changes in human direct reprogrammed neuronal cell model of myotonic dystrophy type 1
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  64. Jun 2022
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    Overlapping transcriptional programs promote survival and axonal regeneration of injured retinal ganglion cells
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    Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons
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  69. May 2022
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    Impact of Raptor and Rictor Deletion on Hippocampal Pathology Following Status Epilepticus
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  71. Mar 2022
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    Hepatoma Derived Growth Factor Enhances Oligodendrocyte Genesis from Subventricular Zone Precursor Cells - Yutong Li, Nicole Leanne Dittmann, Adrianne Eve Scovil Watson, Monique Marylin Alves de Almeida, Tim Footz, Anastassia Voronova, 2022
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    A protocol to differentiate nociceptors, mechanoreceptors, and proprioceptors from human pluripotent stem cells
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    Human cerebral organoids reveal progenitor pathology in EML1-linked cortical malformation
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  75. Jan 2022
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    Fully Characterized Mature Human iPS- and NMP-Derived Motor Neurons Thrive Without Neuroprotection in the Spinal Contusion Cavity
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  77. Nov 2021
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    Rescue of α-synuclein aggregation in Parkinson’s patient neurons by synergistic enhancement of ER proteostasis and protein trafficking
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  79. Oct 2021
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    Generation of human induced pluripotent stem cell line, KRIBBi003-A, from urinary cells of a patient with glycogen storage disease type IXa
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    Rheb-regulated mitochondrial pyruvate metabolism of Schwann cells linked to axon stability
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  82. Sep 2021
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    Generation of an ACTA2-EGFP reporter human induced pluripotent stem cell line, KITi001-C-41, using CRISPR/Cas9-mediated homologous recombination
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  84. Aug 2021
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    Transplantable human motor networks as a neuron-directed strategy for spinal cord injury
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  86. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Ephrin-A3 Is Required for Tonotopic Map Precision and Auditory Functions in the Mouse Auditory Brainstem
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    A Translational Repression Complex in Developing Mammalian Neural Stem Cells that Regulates Neuronal Specification
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  88. Jul 2021
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    Reduced synchroneity of intra-islet Ca2+ oscillations in vivo in Robo-deficient β cells
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    ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function
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  92. Jun 2021
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    The CTNNBIP1-CLSTN1 fusion transcript regulates human neocortical development
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    SORL1 deficiency in human excitatory neurons causes APP-dependent defects in the endolysosome-autophagy network
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  95. May 2021
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    Spatiotemporal mapping of sensory and motor innervation of the embryonic and postnatal mouse urinary bladder.
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    Deconstructing Stepwise Fate Conversion of Human Fibroblasts to Neurons by MicroRNAs
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  98. Mar 2021
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    Human spinal GABA neurons alleviate spasticity and improve locomotion in rats with spinal cord injury
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  100. Feb 2021
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    A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages
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    Lymph nodes are innervated by a unique population of sensory neurons with immunomodulatory potential
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    Familial Alzheimer’s Disease Mutations in PSEN1 Lead to Premature Human Stem Cell Neurogenesis
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    Nogo receptor antagonist LOTUS exerts suppression on axonal growth‐inhibiting receptor PIR‐B
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  105. Dec 2020
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    Establishment human induced pluripotent stem cell line from idiopathic non-familial Parkinson’s Disease patient using self-replicating RNA vector
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  107. Oct 2020
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    A CRISPR-strategy for the generation of a detectable fluorescent hESC reporter line (WAe009-A-37) for the subpallial determinant GSX2
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  109. Sep 2020
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    Generation of RNA-based human induced pluripotent stem cell line from Alzheimer’s Disease patient with PSEN2 N141I mutation
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    Adaptive Thermogenesis in Mice Is Enhanced by Opsin 3-Dependent Adipocyte Light Sensing
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    Axon-dependent expression of YAP/TAZ mediates Schwann cell remyelination but not proliferation after nerve injury
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  113. www.eneuro.org www.eneuro.org
    Collapsin response mediator protein 4 (CRMP4) facilitates Wallerian degeneration and axon regeneration following sciatic nerve injury
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    PI3K isoform-selective inhibition in neuron-specific PTEN-deficient mice rescues molecular defects and reduces epilepsy-associated phenotypes
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  115. Jan 2020
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease
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    Pum2 Shapes the Transcriptome in Developing Axons through Retention of Target mRNAs in the Cell Body
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    Direct Reprogramming of Human Neurons Identifies MARCKSL1 as a Pathogenic Mediator of Valproic Acid-Induced Teratogenicity
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    MicroRNA inhibition upregulates hippocampal A-type potassium current and reduces seizure frequency in a mouse model of epilepsy
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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  122. Nov 2018
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    iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications
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    Tau Does Not Stabilize Axonal Microtubules but Rather Enables Them to Have Long Labile Domains
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    The Soluble Form of LOTUS inhibits Nogo Receptor-Mediated Signaling by Interfering with the Interaction Between Nogo Receptor Type 1 and p75 Neurotrophin Receptor
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    Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian Brain
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    Generation of a PXR reporter human induced pluripotent stem cell line (PXR-mCherry hiPSC) using the CRISPR/Cas9 system
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  128. Nov 2017
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    Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian Brain
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