100 Matching Annotations
  1. Sep 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Generation of footprint-free human induced pluripotent stem cell line (SCIKFi001-B) from cGMP grade umbilical cord-derived mesenchymal stem cells (UC-MSCs) using episomal-plasmid based reprogramming approach
    1
    1. scibot 26 Sep 2024
      RRID:AB_2564645

      DOI: 10.1016/j.scr.2024.103566

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    sciencedirect.com/science/article/pii/S1873506124002642
  3. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sex‐dimorphic effects of biogenesis of lysosome‐related organelles complex‐1 deficiency on mouse perinatal brain development
    1
    1. scibot 25 Sep 2024
      RRID:AB_2564645

      DOI: 10.1002/jnr.24620

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24620
  4. www.sciencedirect.com www.sciencedirect.com
    TAG-1 Multifunctionality Coordinates Neuronal Migration, Axon Guidance, and Fasciculation
    1
    1. scibot 25 Sep 2024
      RRID:AB_2313773

      DOI: 10.1016/j.celrep.2019.12.085

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    sciencedirect.com/science/article/pii/S2211124719317504
  5. www.eneuro.org www.eneuro.org
    Nociceptor deletion of Tsc2 enhances axon regeneration by inducing a conditioning injury response in dorsal root ganglia
    1
    1. scibot 25 Sep 2024
      RRID:AB_291637

      DOI: 10.1523/ENEURO.0168-19.2019

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    eneuro.org/content/6/3/ENEURO.0168-19.2019
  6. www.sciencedirect.com www.sciencedirect.com
    miR-92 Suppresses Robo1 Translation to Modulate Slit Sensitivity in Commissural Axon Guidance
    1
    1. scibot 25 Sep 2024
      RRID:AB_2564645

      DOI: 10.1016/j.celrep.2018.08.021

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      Curator: @evieth

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    sciencedirect.com/science/article/pii/S2211124718312750
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deletion of Tsc2 in Nociceptors Reduces Target Innervation, Ion Channel Expression, and Sensitivity to Heat
    1
    1. scibot 25 Sep 2024
      RRID:AB_291637

      DOI: 10.1523/ENEURO.0436-17.2018

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC5952427/
  8. Jul 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Comparative transcriptomic profiling reveals a role for Olig1 in promoting axon regeneration
    1
    1. scibot 17 Jul 2024
      AB_2564645

      DOI: 10.1016/j.celrep.2024.114514

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    sciencedirect.com/science/article/pii/S221112472400843X
  10. Jun 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microphthalmia and disrupted retinal development due to a LacZ knock-in/knock-out allele at the Vsx2 locus
    1
    1. scibot 27 Jun 2024
      AB_2564645

      DOI: 10.1101/2024.06.08.597937

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    ncbi.nlm.nih.gov/pmc/articles/PMC11185793/
  12. www.sciencedirect.com www.sciencedirect.com
    CGG repeats in the human FMR1 gene regulate mRNA localization and cellular stress in developing neurons
    1
    1. scibot 21 Jun 2024
      RRID:AB_2564645

      DOI: 10.1016/j.celrep.2024.114330

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    sciencedirect.com/science/article/pii/S2211124724006582
  13. May 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Nuclear aggregates of NONO/SFPQ and A-to-I-edited RNA in Parkinson’s disease and dementia with Lewy bodies
    1
    1. scibot 21 May 2024
      RRID:AB_2564645

      DOI: 10.1016/j.neuron.2024.05.003

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    sciencedirect.com/science/article/pii/S0896627324003283
  15. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 infection exacerbates the cellular pathology of Parkinson’s disease in human dopaminergic neurons and a mouse model
    1
    1. scibot 16 May 2024
      RRID:AB_2564645

      DOI: 10.1016/j.xcrm.2024.101570

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    sciencedirect.com/science/article/pii/S2666379124002623
  16. www.biorxiv.org www.biorxiv.org
    Mouse α-synuclein fibrils are structurally and functionally distinct from human fibrils associated with Lewy body diseases
    1
    1. scibot 16 May 2024
      RRID:AB_2564645

      DOI: 10.1101/2024.05.09.593334

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    biorxiv.org/content/10.1101/2024.05.09.593334v1
  17. Apr 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Human spinal GABA neurons alleviate spasticity and improve locomotion in rats with spinal cord injury
    1
    1. scibot 30 Apr 2024
      RRID:AB_2564645

      DOI: 10.1016/j.celrep.2021.108889

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    sciencedirect.com/science/article/pii/S2211124721002035
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Olfactory bulb anomalies in KBG syndrome mouse model and patients
    1
    1. scibot 18 Apr 2024
      RRID:AB_2564645

      DOI: 10.1186/s12916-024-03363-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11017579/
  20. www.sciencedirect.com www.sciencedirect.com
    Cnicin promotes functional nerve regeneration
    1
    1. scibot 16 Apr 2024
      RRID:AB_2564645

      DOI: 10.1016/j.phymed.2024.155641

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    sciencedirect.com/science/article/pii/S0944711324003003
  21. www.sciencedirect.com www.sciencedirect.com
    Parasympathetic neurons derived from human pluripotent stem cells model human diseases and development
    1
    1. scibot 12 Apr 2024
      Biolegend802001; RRID: AB_2564645

      DOI: 10.1016/j.stem.2024.03.011

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    sciencedirect.com/science/article/pii/S1934590924000924
  22. www.nature.com www.nature.com
    Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
    1
    1. scibot 05 Apr 2024
      RRID:AB_2564645

      DOI: 10.1038/s41419-024-06534-8

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    nature.com/articles/s41419-024-06534-8
  23. Mar 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TEAD1 is crucial for developmental myelination, Remak bundles, and functional regeneration of peripheral nerves
    1
    1. scibot 27 Mar 2024
      RRID:AB_2564645

      DOI: 10.7554/eLife.87394

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959528/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Local mitochondrial replication in the periphery of neurons requires the eEF1A1 protein and thetranslation of nuclear-encoded proteins
    1
    1. scibot 23 Mar 2024
      RRID:AB_2564645

      DOI: 10.1016/j.isci.2024.109136

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    ncbi.nlm.nih.gov/pmc/articles/PMC10951640/
  26. www.sciencedirect.com www.sciencedirect.com
    Alternative splicing decouples local from global PRC2 activity
    1
    1. scibot 06 Mar 2024
      RRID:AB_2564645

      DOI: 10.1016/j.molcel.2024.02.011

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    sciencedirect.com/science/article/pii/S1097276524001308
  27. Feb 2024
  28. www.sciencedirect.com www.sciencedirect.com
    Neuronal reprogramming of mouse and human fibroblasts using transcription factors involved in suprachiasmatic nucleus development
    2
    1. scibot 29 Feb 2024
      RRID:AB_2564645

      DOI: 10.1016/j.isci.2024.109051

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    2. scibot 28 Feb 2024
      RRID:AB_2564645

      DOI: 10.1016/j.isci.2024.109051

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    sciencedirect.com/science/article/pii/S2589004224002724
  29. Jan 2024
  30. www.sciencedirect.com www.sciencedirect.com
    Protocol for the isolation and culture of microglia, astrocytes, and neurons from the same mouse brain
    1
    1. scibot 18 Jan 2024
      RRID:AB_2564645

      DOI: 10.1016/j.xpro.2023.102804

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    sciencedirect.com/science/article/pii/S2666166723007712
  31. Dec 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Characterization of two human induced pluripotent stem cell lines derived from Batten disease patient fibroblasts harbouring CLN5 mutations
    1
    1. scibot 23 Dec 2023
      AB_2564645

      DOI: 10.1016/j.scr.2023.103291

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    sciencedirect.com/science/article/pii/S1873506123002775
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mir324 knockout regulates the structure of dendritic spines and impairs hippocampal long-term potentiation
    1
    1. scibot 15 Dec 2023
      RRID:AB_2564645

      DOI: 10.1038/s41598-023-49134-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC10713680/
  34. www.sciencedirect.com www.sciencedirect.com
    Phase I clinical trial of intracerebroventricular transplantation of allogeneic neural stem cells in people with progressive multiple sclerosis
    1
    1. scibot 01 Dec 2023
      RRID:AB_2564645

      DOI: 10.1016/j.stem.2023.11.001

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    sciencedirect.com/science/article/pii/S1934590923003934
  35. Nov 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Loss of Baz1b in mice causes perinatal lethality, growth failure, and variable multi-system outcomes
    1
    1. scibot 10 Nov 2023
      RRID:AB_2564645

      DOI: 10.1016/j.ydbio.2023.09.007

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    sciencedirect.com/science/article/pii/S0012160623001616
  37. www.sciencedirect.com www.sciencedirect.com
    APOE4-promoted gliosis and degeneration in tauopathy are ameliorated by pharmacological inhibition of HMGB1 release
    1
    1. scibot 02 Nov 2023
      RRID:AB_2564645

      DOI: 10.1016/j.celrep.2023.113252

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    sciencedirect.com/science/article/pii/S2211124723012640
  38. Oct 2023
  39. www.nature.com www.nature.com
    Chromatin-modifying enzymes as modulators of nuclear size during lineage differentiation
    1
    1. scibot 21 Oct 2023
      RRID:AB_2564645

      DOI: 10.1038/s41420-023-01639-z

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    nature.com/articles/s41420-023-01639-z
  40. www.sciencedirect.com www.sciencedirect.com
    Three-dimensional reconstructions of mechanosensory end organs suggest a unifying mechanism underlying dynamic, light touch
    1
    1. scibot 01 Oct 2023
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      DOI: 10.1016/j.neuron.2023.08.023

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    sciencedirect.com/science/article/pii/S0896627323006347
  41. Sep 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    One-step cell biomanufacturing platform: porous gelatin microcarrier beads promote human embryonic stem cell-derived midbrain dopaminergic progenitor cell differentiation in vitro and survival after transplantation in vivo
    1
    1. scibot 20 Sep 2023
      AB_2564645

      DOI: 10.4103/1673-5374.377412

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    ncbi.nlm.nih.gov/pmc/articles/PMC10503631/
  43. www.sciencedirect.com www.sciencedirect.com
    Human iPS cell-derived sensory neurons can be infected by SARS-CoV-2
    1
    1. scibot 07 Sep 2023
      RRID:AB_2564645

      DOI: 10.1016/j.isci.2023.107690

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    sciencedirect.com/science/article/pii/S2589004223017674
  44. Aug 2023
  45. www.sciencedirect.com www.sciencedirect.com
    DRG afferents that mediate physiologic and pathologic mechanosensation from the distal colon
    1
    1. scibot 04 Aug 2023
      RRID:AB_2564645

      DOI: 10.1016/j.cell.2023.07.007

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    sciencedirect.com/science/article/pii/S0092867423007407
  46. Jul 2023
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Estradiol- and Progesterone-Associated Changes in microRNA-Induced Silencing and Reduced Antiseizure Efficacy of an Antagomir in Female Mice
    1
    1. scibot 27 Jul 2023
      RRID:AB_2564645

      DOI: 10.1523/ENEURO.0047-22.2023

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    ncbi.nlm.nih.gov/pmc/articles/PMC10368146/
  48. Jun 2023
  49. anatomypubs.onlinelibrary.wiley.com anatomypubs.onlinelibrary.wiley.com
    A framework to identify functional interactors that contribute to disrupted early retinal development in Vsx2 ocular retardation J mice
    1
    1. scibot 03 Jun 2023
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      DOI: 10.1002/dvdy.629

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    anatomypubs.onlinelibrary.wiley.com/doi/10.1002/dvdy.629
  50. May 2023
  51. www.sciencedirect.com www.sciencedirect.com
    Prox2 and Runx3 vagal sensory neurons regulate esophageal motility
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    1. scibot 17 May 2023
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      DOI: 10.1016/j.neuron.2023.04.025

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    sciencedirect.com/science/article/pii/S089662732300332X
  52. www.sciencedirect.com www.sciencedirect.com
    Methods for culturing adult CNS neurons reveal a CNS conditioning effect
    1
    1. scibot 05 May 2023
      RRID:AB_2564645

      DOI: 10.1016/j.crmeth.2022.100255

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    sciencedirect.com/science/article/pii/S266723752200128X
  53. Mar 2023
  54. www.sciencedirect.com www.sciencedirect.com
    Generation of a PDGFRB-mCherry knock-in reporter human induced pluripotent stem cell line (KITi001-A-1), using CRISPR/Cas9 nuclease
    1
    1. scibot 28 Mar 2023
      PRID: AB_2564645

      DOI: 10.1016/j.scr.2023.103081

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    sciencedirect.com/science/article/pii/S1873506123000673
  55. www.sciencedirect.com www.sciencedirect.com
    The P-body protein 4E-T represses translation to regulate the balance between cell genesis and establishment of the postnatal NSC pool
    1
    1. scibot 16 Mar 2023
      RRID:AB_2564645

      DOI: 10.1016/j.celrep.2023.112242

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  56. Feb 2023
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    Generation of telomeric repeat binding factor 1 (TRF1)-knockout human embryonic stem cell lines, KRIBBe010-A-95, KRIBBe010-A-96, and KRIBBe010-A-97, using CRISPR/Cas9 technology
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  58. Jan 2023
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    Epiblast-like stem cells established by Wnt/β-catenin signaling manifest distinct features of formative pluripotency and germline competence
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    Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons
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    Brain-derived neurotrophic factor (BDNF) induces antagonistic action to Nogo signaling by the upregulation of lateral olfactory tract usher substance (LOTUS) expression
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    Human cortical interneurons optimized for grafting specifically integrate, abort seizures, and display prolonged efficacy without over-inhibition
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    Culture Protocol and Transcriptomic Analysis of Murine SVZ NPCs and OPCs
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  64. Dec 2022
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    Generation of human elongating multi-lineage organized cardiac gastruloids
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    Establishment of a human embryonic stem cell line, WAe009-A-99, with constitutive expression of the dCas9-p300 fusion protein
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  67. Nov 2022
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    Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis
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  69. Oct 2022
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    Targeting RTN4/NoGo-Receptor reduces levels of ALS protein ataxin-2
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  71. Sep 2022
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    Analysis of neuronal injury transcriptional response identifies CTCF and YY1 as co-operating factors regulating axon regeneration
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  73. Aug 2022
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    Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer’s disease
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  75. Jul 2022
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    Pharmacotherapy alleviates pathological changes in human direct reprogrammed neuronal cell model of myotonic dystrophy type 1
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  77. Jun 2022
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    Overlapping transcriptional programs promote survival and axonal regeneration of injured retinal ganglion cells
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    Cholesterol and matrisome pathways dysregulated in astrocytes and microglia
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    A Combined Human Gastruloid Model of Cardiogenesis and Neurogenesis
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    Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons
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  82. May 2022
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    Impact of Raptor and Rictor Deletion on Hippocampal Pathology Following Status Epilepticus
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  84. Mar 2022
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    Hepatoma Derived Growth Factor Enhances Oligodendrocyte Genesis from Subventricular Zone Precursor Cells - Yutong Li, Nicole Leanne Dittmann, Adrianne Eve Scovil Watson, Monique Marylin Alves de Almeida, Tim Footz, Anastassia Voronova, 2022
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    A protocol to differentiate nociceptors, mechanoreceptors, and proprioceptors from human pluripotent stem cells
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    Human cerebral organoids reveal progenitor pathology in EML1-linked cortical malformation
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  88. Jan 2022
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    Fully Characterized Mature Human iPS- and NMP-Derived Motor Neurons Thrive Without Neuroprotection in the Spinal Contusion Cavity
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  90. Nov 2021
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    Rescue of α-synuclein aggregation in Parkinson’s patient neurons by synergistic enhancement of ER proteostasis and protein trafficking
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  92. Oct 2021
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    Generation of human induced pluripotent stem cell line, KRIBBi003-A, from urinary cells of a patient with glycogen storage disease type IXa
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    Rheb-regulated mitochondrial pyruvate metabolism of Schwann cells linked to axon stability
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  95. Sep 2021
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    Generation of an ACTA2-EGFP reporter human induced pluripotent stem cell line, KITi001-C-41, using CRISPR/Cas9-mediated homologous recombination
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  97. Aug 2021
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    Transplantable human motor networks as a neuron-directed strategy for spinal cord injury
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    Ephrin-A3 Is Required for Tonotopic Map Precision and Auditory Functions in the Mouse Auditory Brainstem
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    A Translational Repression Complex in Developing Mammalian Neural Stem Cells that Regulates Neuronal Specification
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  101. Jul 2021
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    Reduced synchroneity of intra-islet Ca2+ oscillations in vivo in Robo-deficient β cells
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    ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function
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  105. Jun 2021
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    The CTNNBIP1-CLSTN1 fusion transcript regulates human neocortical development
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    SORL1 deficiency in human excitatory neurons causes APP-dependent defects in the endolysosome-autophagy network
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  108. May 2021
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    Spatiotemporal mapping of sensory and motor innervation of the embryonic and postnatal mouse urinary bladder.
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    Deconstructing Stepwise Fate Conversion of Human Fibroblasts to Neurons by MicroRNAs
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  111. Mar 2021
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    Human spinal GABA neurons alleviate spasticity and improve locomotion in rats with spinal cord injury
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  113. Feb 2021
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    A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages
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    Lymph nodes are innervated by a unique population of sensory neurons with immunomodulatory potential
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  116. www.sciencedirect.com www.sciencedirect.com
    Familial Alzheimer’s Disease Mutations in PSEN1 Lead to Premature Human Stem Cell Neurogenesis
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  117. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Nogo receptor antagonist LOTUS exerts suppression on axonal growth‐inhibiting receptor PIR‐B
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  118. Dec 2020
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    Establishment human induced pluripotent stem cell line from idiopathic non-familial Parkinson’s Disease patient using self-replicating RNA vector
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  120. Oct 2020
  121. www.sciencedirect.com www.sciencedirect.com
    A CRISPR-strategy for the generation of a detectable fluorescent hESC reporter line (WAe009-A-37) for the subpallial determinant GSX2
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  122. Sep 2020
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    Generation of RNA-based human induced pluripotent stem cell line from Alzheimer’s Disease patient with PSEN2 N141I mutation
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    Adaptive Thermogenesis in Mice Is Enhanced by Opsin 3-Dependent Adipocyte Light Sensing
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  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Axon-dependent expression of YAP/TAZ mediates Schwann cell remyelination but not proliferation after nerve injury
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  126. www.eneuro.org www.eneuro.org
    Collapsin response mediator protein 4 (CRMP4) facilitates Wallerian degeneration and axon regeneration following sciatic nerve injury
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  127. www.sciencedirect.com www.sciencedirect.com
    PI3K isoform-selective inhibition in neuron-specific PTEN-deficient mice rescues molecular defects and reduces epilepsy-associated phenotypes
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  128. Jan 2020
  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease
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  130. www.sciencedirect.com www.sciencedirect.com
    Pum2 Shapes the Transcriptome in Developing Axons through Retention of Target mRNAs in the Cell Body
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  131. www.sciencedirect.com www.sciencedirect.com
    Direct Reprogramming of Human Neurons Identifies MARCKSL1 as a Pathogenic Mediator of Valproic Acid-Induced Teratogenicity
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  132. www.sciencedirect.com www.sciencedirect.com
    MicroRNA inhibition upregulates hippocampal A-type potassium current and reduces seizure frequency in a mouse model of epilepsy
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  134. www.sciencedirect.com www.sciencedirect.com
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  135. Nov 2018
  136. www.sciencedirect.com www.sciencedirect.com
    iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications
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  137. www.sciencedirect.com www.sciencedirect.com
    Tau Does Not Stabilize Axonal Microtubules but Rather Enables Them to Have Long Labile Domains
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  138. www.jneurosci.org www.jneurosci.org
    The Soluble Form of LOTUS inhibits Nogo Receptor-Mediated Signaling by Interfering with the Interaction Between Nogo Receptor Type 1 and p75 Neurotrophin Receptor
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  139. www.cell.com www.cell.com
    Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian Brain
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  140. www.sciencedirect.com www.sciencedirect.com
    Generation of a PXR reporter human induced pluripotent stem cell line (PXR-mCherry hiPSC) using the CRISPR/Cas9 system
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  141. Nov 2017
  142. www.sciencedirect.com www.sciencedirect.com
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  143. www.sciencedirect.com www.sciencedirect.com
    Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian Brain
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