113 Matching Annotations
  1. Nov 2024
  2. www.jneurosci.org www.jneurosci.org
    A Systematic Structure-Function Characterization of a Human Mutation in Neurexin-3α Reveals an Extracellular Modulatory Sequence That Stabilizes Neuroligin-1 Binding to Enhance the Postsynaptic Properties of Excitatory Synapses
    1
    1. scibot 07 Nov 2024
      RRID:AB_2565006

      DOI: 10.1523/JNEUROSCI.1847-23.2024

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    jneurosci.org/content/44/41/e1847232024
  3. Oct 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels
    1
    1. scibot 05 Oct 2024
      RRID:AB_2565006

      DOI: 10.1016/j.celrep.2024.114428

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    ncbi.nlm.nih.gov/pmc/articles/PMC11441329/
  5. Sep 2024
  6. www.sciencedirect.com www.sciencedirect.com
    The Aspartic Protease Ddi1 Contributes to DNA-Protein Crosslink Repair in Yeast
    1
    1. scibot 25 Sep 2024
      RRID:AB_2565006

      DOI: 10.1016/j.molcel.2019.12.007

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    sciencedirect.com/science/article/pii/S1097276519308986
  7. www.eneuro.org www.eneuro.org
    The Expression of Key Guidance Genes at a Forebrain Axon Turning Point Is Maintained by Distinct Fgfr Isoforms but a Common Downstream Signal Transduction Mechanism
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1523/ENEURO.0086-19.2019

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      Curator comments: Influenza Hemagglutinin Epitope (YPYDVPDYA) Antibody Covance Research Products Inc Cat# MMS-101P

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    eneuro.org/content/6/2/ENEURO.0086-19.2019
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ARL3 GTPases facilitate ODA16 unloading from IFT in motile cilia
    1
    1. scibot 12 Sep 2024
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      DOI: 10.1126/sciadv.adq2950

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    ncbi.nlm.nih.gov/pmc/articles/PMC11373600/
  9. Aug 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphoglycerate kinase is a central leverage point in Parkinson’s disease–driven neuronal metabolic deficits
    1
    1. scibot 23 Aug 2024
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      DOI: 10.1126/sciadv.adn6016

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    ncbi.nlm.nih.gov/pmc/articles/PMC11338267/
  11. www.nature.com www.nature.com
    Distinct active zone protein machineries mediate Ca2+ channel clustering and vesicle priming at hippocampal synapses
    1
    1. scibot 23 Aug 2024
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      DOI: 10.1038/s41593-024-01720-5

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    nature.com/articles/s41593-024-01720-5
  12. www.sciencedirect.com www.sciencedirect.com
    The structure of the Orm2-containing serine palmitoyltransferase complex reveals distinct inhibitory potentials of yeast Orm proteins
    1
    1. scibot 22 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114627

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    sciencedirect.com/science/article/pii/S221112472400977X
  13. www.sciencedirect.com www.sciencedirect.com
    Sestrin2 drives ER-phagy in response to protein misfolding
    1
    1. scibot 18 Aug 2024
      RRID:AB_2565006

      DOI: 10.1016/j.devcel.2024.07.004

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    sciencedirect.com/science/article/pii/S1534580724004416
  14. dx.doi.org dx.doi.org
    The cullin Rtt101 promotes ubiquitin-dependent DNA−protein crosslink repair across the cell cycle
    1
    1. scibot 18 Aug 2024
      RRID:AB_2565006

      DOI: 10.1093/nar/gkae658

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    dx.doi.org/10.1093/nar/gkae658
  15. Jul 2024
  16. www.sciencedirect.com www.sciencedirect.com
    Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer
    1
    1. scibot 25 Jul 2024
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      DOI: 10.1016/j.ccell.2024.06.012

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    sciencedirect.com/science/article/pii/S153561082400237X
  17. May 2024
  18. www.biorxiv.org www.biorxiv.org
    IFIT1 is rapidly evolving and exhibits disparate antiviral activities across 11 mammalian orders
    1
    1. scibot 23 May 2024
      RRID:AB_2565006

      DOI: 10.1101/2024.05.13.593954

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    biorxiv.org/content/10.1101/2024.05.13.593954v1
  19. Apr 2024
  20. www.sciencedirect.com www.sciencedirect.com
    Unprocessed genomic uracil as a source of DNA replication stress in cancer cells
    1
    1. scibot 30 Apr 2024
      BioLegend901501

      DOI: 10.1016/j.molcel.2024.04.004

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    sciencedirect.com/science/article/pii/S109727652400282X
  21. Mar 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors
    1
    1. scibot 27 Mar 2024
      RRID:AB_2565006

      DOI: 10.1083/jcb.202307092

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959120/
  23. www.sciencedirect.com www.sciencedirect.com
    Discovery of SQSTM1/p62-dependent P-bodies that regulate the NLRP3 inflammasome
    2
    1. scibot 12 Mar 2024
      RRID:AB_2565006

      DOI: 10.1016/j.celrep.2024.113935

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    2. scibot 12 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113935

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    sciencedirect.com/science/article/pii/S2211124724002638
  24. www.sciencedirect.com www.sciencedirect.com
    HDAC5 enhances IRF3 activation and is targeted for degradation by protein C6 from orthopoxviruses including Monkeypox virus and Variola virus
    1
    1. scibot 12 Mar 2024
      RRID:AB_2565006

      DOI: 10.1016/j.celrep.2024.113788

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    sciencedirect.com/science/article/pii/S2211124724001165
  25. Feb 2024
  26. www.sciencedirect.com www.sciencedirect.com
    CAG repeat expansions create splicing acceptor sites and produce aberrant repeat-containing RNAs
    1
    1. scibot 02 Feb 2024
      RRID:AB_2565006

      DOI: 10.1016/j.molcel.2024.01.006

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    sciencedirect.com/science/article/pii/S1097276524000078
  27. Jan 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The intracellular C-terminus confers compartment-specific targeting of voltage-gated Ca2+ channels
    1
    1. scibot 18 Jan 2024
      RRID:AB_2565006

      DOI: 10.1101/2023.12.23.573183

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    ncbi.nlm.nih.gov/pmc/articles/PMC10769351/
  29. Dec 2023
  30. www.biorxiv.org www.biorxiv.org
    Neuronal exosomes transport a miRNA/RISC cargo to preserve germline stem cell integrity during energy stress
    1
    1. scibot 01 Dec 2023
      RRID:AB_2565006

      DOI: 10.1101/2023.11.15.567290

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    biorxiv.org/content/10.1101/2023.11.15.567290v1
  31. Nov 2023
  32. www.biorxiv.org www.biorxiv.org
    Molecular definition of distinct active zone protein machineries for Ca2+ channel clustering and synaptic vesicle priming
    1
    1. scibot 10 Nov 2023
      RRID:AB_2565006

      DOI: 10.1101/2023.10.27.564439

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    biorxiv.org/content/10.1101/2023.10.27.564439v1
  33. Oct 2023
  34. www.biorxiv.org www.biorxiv.org
    The Interferon-inducible NAMPT acts as a protein phosphoribosylase to restrict viral infection
    1
    1. scibot 24 Oct 2023
      RRID:AB_2565006

      DOI: 10.1101/2023.10.12.562112

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    biorxiv.org/content/10.1101/2023.10.12.562112v1
  35. Sep 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Hormonal gatekeeping via the blood-brain barrier governs caste-specific behavior in ants
    1
    1. scibot 08 Sep 2023
      RRID:AB_2565006

      DOI: 10.1016/j.cell.2023.08.002

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    sciencedirect.com/science/article/abs/pii/S0092867423008565
  37. www.sciencedirect.com www.sciencedirect.com
    TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation
    1
    1. scibot 07 Sep 2023
      RRID:AB_2565006

      DOI: 10.1016/j.celrep.2023.113070

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    sciencedirect.com/science/article/pii/S2211124723010811
  38. Jun 2023
  39. www.sciencedirect.com www.sciencedirect.com
    ECPAS/Ecm29-mediated 26S proteasome disassembly is an adaptive response to glucose starvation
    1
    1. scibot 29 Jun 2023
      RRID:AB_2565006

      DOI: 10.1016/j.celrep.2023.112701

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    sciencedirect.com/science/article/pii/S221112472300712X
  40. www.sciencedirect.com www.sciencedirect.com
    A functional link between lariat debranching enzyme and the intron-binding complex is defective in non-photosensitive trichothiodystrophy
    1
    1. scibot 28 Jun 2023
      RRID:AB_2565006

      DOI: 10.1016/j.molcel.2023.06.011

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    sciencedirect.com/science/article/pii/S1097276523004331
  41. www.sciencedirect.com www.sciencedirect.com
    Advanced human iPSC-based preclinical model for Parkinson’s disease with optogenetic alpha-synuclein aggregation
    1
    1. scibot 21 Jun 2023
      RRID:AB_2565006

      DOI: 10.1016/j.stem.2023.05.015

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    sciencedirect.com/science/article/pii/S1934590923002114
  42. May 2023
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reprogramming of Iron Metabolism Confers Ferroptosis Resistance in ECM-Detached Cells
    1
    1. scibot 27 May 2023
      RRID:AB_2565006

      DOI: 10.1016/j.isci.2023.106827

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    ncbi.nlm.nih.gov/pmc/articles/PMC10209538/
  44. www.sciencedirect.com www.sciencedirect.com
    Metamorphic proteins at the basis of human autophagy initiation and lipid transfer
    1
    1. scibot 20 May 2023
      AB_2565006

      DOI: 10.1016/j.molcel.2023.04.026

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    sciencedirect.com/science/article/pii/S1097276523003210
  45. www.sciencedirect.com www.sciencedirect.com
    Human papillomavirus E5 suppresses immunity via inhibition of the immunoproteasome and STING pathway
    1
    1. scibot 12 May 2023
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      DOI: 10.1016/j.celrep.2023.112508

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    sciencedirect.com/science/article/pii/S2211124723005193
  46. www.embopress.org www.embopress.org
    Ubx5-Cdc48 assists the protease Wss1 at DNA-protein crosslink sites in yeast
    1
    1. scibot 06 May 2023
      RRID:AB_2565006

      DOI: 10.15252/embj.2023113609

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    embopress.org/doi/10.15252/embj.2023113609
  47. www.nature.com www.nature.com
    SLITRK2 variants associated with neurodevelopmental disorders impair excitatory synaptic function and cognition in mice
    1
    1. scibot 05 May 2023
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      DOI: 10.1038/s41467-022-31566-z

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    nature.com/articles/s41467-022-31566-z
  48. Apr 2023
  49. www.sciencedirect.com www.sciencedirect.com
    Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut
    1
    1. scibot 20 Apr 2023
      RRID:AB_2565006

      DOI: 10.1016/j.chom.2023.03.007

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    sciencedirect.com/science/article/pii/S1931312823001117
  50. Mar 2023
  51. www.sciencedirect.com www.sciencedirect.com
    The P-body protein 4E-T represses translation to regulate the balance between cell genesis and establishment of the postnatal NSC pool
    1
    1. scibot 16 Mar 2023
      RRID:AB_2565006

      DOI: 10.1016/j.celrep.2023.112242

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    sciencedirect.com/science/article/pii/S221112472300253X
  52. www.sciencedirect.com www.sciencedirect.com
    LMAN1 is a receptor for house dust mite allergens
    1
    1. scibot 11 Mar 2023
      RRID:AB_2565006

      DOI: 10.1016/j.celrep.2023.112208

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    sciencedirect.com/science/article/pii/S221112472300219X
  53. www.science.org www.science.org
    Regulation of cargo exocytosis by a Reps1-Ralbp1-RalA module
    1
    1. scibot 02 Mar 2023
      RRID:AB_2565006

      DOI: 10.1126/sciadv.ade2540

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    science.org/doi/10.1126/sciadv.ade2540
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of cargo exocytosis by a Reps1-Ralbp1-RalA module
    1
    1. scibot 02 Mar 2023
      RRID:AB_2565006

      DOI: 10.1126/sciadv.ade2540

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    ncbi.nlm.nih.gov/pmc/articles/PMC9946360/
  55. Feb 2023
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein composition of axonal dopamine release sites in the striatum
    1
    1. scibot 23 Feb 2023
      RRID:AB_2565006

      DOI: 10.7554/eLife.83018

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    ncbi.nlm.nih.gov/pmc/articles/PMC9937654/
  57. Jan 2023
  58. www.sciencedirect.com www.sciencedirect.com
    Unique interface and dynamics of the complex of HSP90 with a specialized cochaperone AIPL1
    1
    1. scibot 19 Jan 2023
      RRID:AB_2565006

      DOI: 10.1016/j.str.2022.12.014

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    sciencedirect.com/science/article/pii/S0969212622005238
  59. Dec 2022
  60. www.sciencedirect.com www.sciencedirect.com
    IL-17/CXCL5 signaling within the oligovascular niche mediates human and mouse white matter injury
    1
    1. scibot 24 Dec 2022
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  61. Nov 2022
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    Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation
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    PI(4,5)P 2-stimulated positive feedback drives the recruitment of Dishevelled to Frizzled in Wnt-β-catenin signaling
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    A synthetic biology approach reveals diverse and dynamic CDK response profiles via multisite phosphorylation of NLS-NES modules
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  65. Oct 2022
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    PI(4,5)P 2-stimulated positive feedback drives the recruitment of Dishevelled to Frizzled in Wnt-β-catenin signaling
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  67. Aug 2022
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    A synthetic biology approach reveals diverse and dynamic CDK response profiles via multisite phosphorylation of NLS-NES modules
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  69. Jul 2022
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    A RET::GRB2 fusion in pheochromocytoma defies the classic paradigm of RET oncogenic fusions
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  71. Jun 2022
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    14-3-3θ does not protect against behavioral or pathological deficits in Alzheimer's disease mouse models
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    Melanomas with concurrent BRAF non-p.V600 and NF1 loss-of-function mutations are targetable by BRAF/MEK inhibitor combination therapy
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    BMI-1 regulates DNA end resection and homologous recombination repair
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    AP-4-mediated axonal transport controls endocannabinoid production in neurons
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    The role of Even-skipped in Drosophila larval somatosensory circuit assembly
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  79. Feb 2022
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    Transgenerational inheritance of sexual attractiveness via small RNAs enhances evolvability in C. elegans
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  82. Jan 2022
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    STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses
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  84. Nov 2021
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    SUMO orchestrates multiple alternative DNA-protein crosslink repair pathways
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    Kr-h1 maintains distinct caste-specific neurotranscriptomes in response to socially regulated hormones
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  87. Oct 2021
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    Aberrant RNA methylation triggers recruitment of an alkylation repair complex
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    Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis
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  90. Sep 2021
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    Endosomal trafficking and DNA damage checkpoint kinases dictate survival to replication stress by regulating amino acid uptake and protein synthesis
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    The RNA-binding protein Musashi controls axon compartment-specific synaptic connectivity through ptp69D mRNA poly(A)-tailing
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    Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter
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    Alleviation of neuropathic pain by over-expressing a soluble colony-stimulating factor 1 receptor to suppress microgliosis and macrophage accumulation
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  95. Aug 2021
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    Golgi-independent secretory trafficking through recycling endosomes in neuronal dendrites and spines
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  100. Jul 2021
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    Vaccinia Virus Ankyrin-Repeat/F-Box Protein Targets Interferon-Induced IFITs for Proteasomal Degradation
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      Mouse monoclonal anti-HA (clone 16B12)

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    Impaired axonal retrograde trafficking of the retromer complex augments lysosomal deficits in Alzheimer’s disease neurons
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    A Brucella Type IV Effector Targets the COG Tethering Complex to Remodel Host Secretory Traffic and Promote Intracellular Replication
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    Temporal Cohorts of Lineage-Related Neurons Perform Analogous Functions in Distinct Sensorimotor Circuits
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    Action potential-coupled Rho GTPase signaling drives presynaptic plasticity
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  108. www.nature.com www.nature.com
    FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates
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  109. Jun 2021
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    Gating and modulation of a hetero-octameric AMPA glutamate receptor
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    PKC-phosphorylation of Liprin-α3 triggers phase separation and controls presynaptic active zone structure
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  112. May 2021
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    Toxoplasma gondii secreted effectors co-opt host repressor complexes to inhibit necroptosis
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  115. Apr 2021
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    Distinct PRC2 subunits regulate maintenance and establishment of Polycomb repression during differentiation
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    Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
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  119. Mar 2021
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  121. www.embopress.org www.embopress.org
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  122. Feb 2021
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    The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma
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  125. Nov 2020
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    Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry
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    LAR-RPTPs Directly Interact with Neurexins to Coordinate Bidirectional Assembly of Molecular Machineries
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  128. Sep 2020
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    Proline-Rich Motifs Control G2-CDK Target Phosphorylation and Priming an Anchoring Protein for Polo Kinase Localization
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    Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining
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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cholinergic Synaptic Homeostasis Is Tuned by an NFAT-Mediated α7 nAChR-Kv4/Shal Coupled Regulatory System
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    Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12
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  134. Jan 2020
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    Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation
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    Poly(ADP-Ribose) Polymerase 2 Recruits Replication Protein A to Sites of LINE-1 Integration to Facilitate Retrotransposition
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    AAGAB Controls AP2 Adaptor Assembly in Clathrin-Mediated Endocytosis
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  139. elifesciences.org elifesciences.org
    Nedd4 E3 ligase and beta-arrestins regulate ubiquitination, trafficking, and stability of the mGlu7 receptor
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    How prolonged expression of Hunchback, a temporal transcription factor, re-wires locomotor circuits
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    Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase
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    CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1
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  144. Nov 2018
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    Inheritance of CENP-A Nucleosomes during DNA Replication Requires HJURP
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    Neuropilin-2/PlexinA3 Receptors Associate with GluA1 and Mediate Sema3F-Dependent Homeostatic Scaling in Cortical Neurons
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  148. europepmc.org europepmc.org
    A versatile genetic tool for post-translational control of gene expression in Drosophila melanogaster.
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  149. Nov 2017
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    cTag-PAPERCLIP Reveals Alternative Polyadenylation Promotes Cell-Type Specific Protein Diversity and Shifts Araf Isoforms with Microglia Activation
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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct Akt phosphorylation states are required for insulin regulated Glut4 and Glut1-mediated glucose uptake
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    BTBD18 Regulates a Subset of piRNA-Generating Loci through Transcription Elongation in Mice
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